Drug & supplement interaction

Agaricus Mushroom + Infliximab

Infliximab brand name: Remicade.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Agaricus Mushroom and Infliximab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Agaricus Mushroom and Infliximab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Infliximab and Agaricus Mushroom in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Agaricus Mushroom safety at a glance

Agaricus Mushroom overall Use caution Generally tolerated as a food, but supplement safety and long-term effects are not well established.
Pregnancy Avoid Not enough safety data, so it is best to avoid supplement doses during pregnancy.
Breastfeeding Avoid Not enough safety data, so avoid supplement doses while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Infliximab and Agaricus Mushroom? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Keep it in perspective

Agaricus Mushroom Does Interact With Other Medications

Agaricus Mushroom has 86 moderate known drug interactions in our database — Infliximab isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Infliximab)
Taking anything else?

Check Another of Your Medications Against Agaricus Mushroom

Covers the 2,830 medications we’ve checked against Agaricus Mushroom. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Agaricus Mushroom and Infliximab May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Agaricus Mushroom

    “An allergic reaction has been reported in a female who took a specific agaricus powder product (Sen-Sei-Ro Powder Gold, Kyowa Wellness Co., Ltd.) 1.8 grams daily by mouth for 2 months. The patient developed an urticarial papular rash which resolved when the product was discontinued. Allergic contact cheilitis was also reported in a patient taking a homemade agaricus mushroom extract orally.”

    Agaricus Mushroom · Natural Medicines adverse-effect record, reported in cheilitis.

    2 sources cited
    1. 17185. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
    2. 94720. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.

    Infliximab

    Listed in the ADVERSE REACTIONS section of the FDA label for Infliximab. Read the label on DailyMed ›

Reported for Agaricus Mushroom but not commonly for Infliximab: stomach upset, an allergic reaction, liver problems and diarrhea.

Effects for Infliximab come from the ADVERSE REACTIONS section of its FDA label; effects for Agaricus Mushroom come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Infliximab Is Prescribed For, and What Agaricus Mushroom Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Infliximab is a prescription medicine with approved uses on its FDA label. Agaricus Mushroom is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Infliximab is prescribed for: Infliximab injection is used to treat several serious inflammatory conditions. It treats moderately to severely active Crohn's disease (including fistulizing disease) and ulcerative colitis in adults, and in children ages 6 and older. It also treats moderately to severely active rheumatoid arthritis (in combination with methotrexate), ankylosing spondylitis (a type of spinal arthritis), psoriatic arthritis, and chronic severe plaque psoriasis in adults. Infliximab is intended for patients whose disease has not responded well enough to conventional therapies.

Read the rest of what Infliximab is prescribed for

It is available under the brand names INFLECTRA, Remicade, and Renflexis, all given by intravenous (IV) infusion.

Agaricus Mushroom has been studied for:

  • Ulcerative colitis studied, not established Agaricus Mushroom has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Agaricus Mushroom for ulcerative colitis

    It is unclear if oral agaricus mushroom is beneficial for ulcerative colitis.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Infliximab on your own; if you are taking Agaricus Mushroom for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

One more smart check

Taking Agaricus Mushroom as Part of a Dietary Supplement Product? Check It for Interactions

We hold 671 real supplement products containing Agaricus Mushroom, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Agaricus Mushroom. Even though Agaricus Mushroom itself has no known interaction with Infliximab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Agaricus Mushroom and Infliximab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Agaricus Mushroom
Top half

#419 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Infliximab
Steady interest

#1,709 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Agaricus Mushroom reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Agaricus Mushroom and Infliximab records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Agaricus Mushroom

What is Agaricus Mushroom?

  • Immune support
  • General wellness and antioxidant
  • Adjunct interest during cancer care
  • Blood sugar support
  • Cholesterol and heart health

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not strong enough to recommend it for treating any disease. If you want to try it, talk with your pharmacist or doctor first, especially if you have a health condition or take other medicines.

Agaricus subrufescens · Agaricaceae · Fruiting body (mushroom), sometimes mycelium · Capsules, tablets, powders, dried mushroom, liquid extracts, teas

An interaction check asks whether these two react with each other — it does not ask whether Agaricus Mushroom is a good idea for someone in your situation. Here is what our Agaricus Mushroom record says about it on its own.

Agaricus Mushroom: dosing

There is no established standard dose for Agaricus mushroom supplements. Studies have used different products and amounts, so it is hard to recommend one specific dose.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount. Choosing products from reputable companies that test for purity is wise, since supplements are not tightly regulated.

From our Agaricus Mushroom monograph — the full record covers uses, side effects and every documented interaction.

Read the full Agaricus Mushroom monograph & all interactions
Medication

About Infliximab Injection

What Is Infliximab Injection Used For?

Brand name: Remicade

Infliximab injection is used to treat several serious inflammatory conditions. It treats moderately to severely active Crohn's disease (including fistulizing disease) and ulcerative colitis in adults, and in children ages 6 and older. It also treats moderately to severely active rheumatoid arthritis (in combination with methotrexate), ankylosing spondylitis (a type of spinal arthritis), psoriatic arthritis, and chronic severe plaque psoriasis in adults.

Infliximab is intended for patients whose disease has not responded well enough to conventional therapies. It is available under the brand names INFLECTRA, Remicade, and Renflexis, all given by intravenous (IV) infusion.

See full Infliximab Injection drug information
Keep checking

Other Drugs & Agaricus Mushroom

Browse every other medication we’ve checked against Agaricus Mushroom — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Agaricus Mushroom page.

No interaction 2,743 drugs checked — show the list

We also checked Agaricus Mushroom against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Agaricus Mushroom list.

See the full Agaricus Mushroom interactions page
See every supplement checked against Infliximab, ranked by severity
Evidence & sources

Agaricus Mushroom References

The 5 references that drive our Agaricus Mushroom monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Hsu CH, Liao YL, Lin SC, et al. The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med 2
  2. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol 2006;36:808-10. PubMed
  3. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
  4. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.
  5. Iwai N, Okuda T, Sawada R, et al. Interstitial lung disease associated with Agaricus blazei Murill in a patient with pancreatic ductal adenocarcinoma receiving gemcitabine-based therapy. Case Rep Gastroenterol 2022;16(1):229-234.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Agaricus Mushroom and Infliximab Together: Common Questions

Is it safe to take Agaricus Mushroom with Infliximab?
We do not list a known interaction between Agaricus Mushroom and Infliximab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Agaricus Mushroom and Infliximab have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Agaricus Mushroom and Infliximab used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Agaricus Mushroom in each. That is a conversation for your prescriber, especially if Infliximab is being adjusted to a target.
Does Agaricus Mushroom interact with any other medications?
Yes. Agaricus Mushroom has 86 documented drug interactions in our database — Infliximab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Agaricus Mushroom monograph Uses, safety profile, and every drug interaction in one place Infliximab Injection drug information The full plain-English guide to this medication Infliximab supplement interactions Every supplement checked against Infliximab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Infliximab and Agaricus Mushroom?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.