Drug & supplement interaction

Damiana + Lurasidone

Lurasidone brand name: Latuda.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Damiana and Lurasidone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Lurasidone states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Damiana and Lurasidone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lurasidone and Damiana in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Damiana safety at a glance

Damiana overall Use caution Likely fine in food/tea amounts for most adults, but human safety data are limited.
Pregnancy Avoid Not enough safety data; avoid during pregnancy.
Breastfeeding Avoid Not enough safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lurasidone and Damiana? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Lurasidone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Lurasidone is filed under 4 classifications — including antipsychotic drugs, seizure threshold lowering drugs, cytochrome p450 3a4 (cyp3a4) substrates. Damiana has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Lurasidone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Damiana Does Interact With Other Medications

Damiana has 86 moderate known drug interactions in our database — Lurasidone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Lurasidone)
Taking anything else?

Check Another of Your Medications Against Damiana

Covers the 2,830 medications we’ve checked against Damiana. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Damiana and Lurasidone May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Seizures Worth acting on Additional detail

    Damiana

    “Orally, 200 grams of damiana extract has caused tetanus-like convulsions and paroxysms resulting in symptoms similar to rabies or strychnine poisoning (4).”

    Damiana · Natural Medicines adverse-effect record, reported in poisoning.

    1 source cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

    Lurasidone

    Listed in the ADVERSE REACTIONS section of the FDA label for Lurasidone. Read the label on DailyMed ›

Effects for Lurasidone come from the ADVERSE REACTIONS section of its FDA label; effects for Damiana come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Lurasidone Products Have a Food Rule — Damiana Should Not Break It

At least one FDA label for a product containing Lurasidone says to take it with food. If you take Damiana on an empty stomach out of habit, keep them separate — and take Lurasidone with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Lurasidone products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION LATUDA should be taken with food (at least 350 calories).

From the Dosage and Administration section of the FDA label we read for Lurasidone — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Overlapping uses

What Lurasidone Is Prescribed For, and What Damiana Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Lurasidone is a prescription medicine with approved uses on its FDA label. Damiana is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Lurasidone is prescribed for: Lurasidone hydrochloride tablets are approved to treat schizophrenia in adults and adolescents aged 13 to 17, and to treat depressive episodes associated with bipolar I disorder (bipolar depression) in adults and children aged 10 to 17. Latuda is one of the brand names under which lurasidone is available as a tablet. For bipolar depression, lurasidone can be used on its own (monotherapy) in adults and pediatric patients aged 10 to 17, or used alongside lithium or valproate (adjunctive therapy) in adults.

Damiana has been studied for:

  • Depression studied, not established Damiana has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Damiana for depression

    Although there has been interest in using oral damiana for depression, there is insufficient reliable information about the clinical effects of damiana for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Lurasidone on your own; if you are taking Damiana for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Damiana or Lurasidone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Damiana or Lurasidone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Lurasidone

This page covers Damiana only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lurasidone page lists 149 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Indian Snakeroot (major), Rauvolfia Vomitoria (major) and St. John's Wort (major).

By severity: 5 major · 104 moderate · 40 minor.

From our pharmacist’s overview on the Lurasidone page

“Supplements deserve real scrutiny alongside lurasidone (Latuda), a medication for schizophrenia and bipolar depression that relies almost entirely on one liver enzyme, CYP3A4, to clear it. Grapefruit blocks that enzyme and can push lurasidone levels high enough to worsen side effects, while St.”

Reviewed by 2 · Jul 18, 2026

Open the Lurasidone interaction page

One more smart check

Taking Damiana as Part of a Dietary Supplement Product? Check It for Interactions

We hold 881 real supplement products containing Damiana, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Damiana. Even though Damiana itself has no known interaction with Lurasidone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Damiana and Lurasidone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Damiana
Top 25%

#213 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lurasidone
Top half

#1,386 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Damiana reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Damiana and Lurasidone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Damiana

What is Damiana?

Damiana
  • Low libido / aphrodisiac
  • Anxiety and stress
  • Mood and mild low energy
  • Digestive upset
  • Headache and general tonic

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small amounts found in teas, but quality studies are lacking, so talk with your pharmacist or doctor before using it—especially if you are pregnant, breastfeeding, or have a health condition.

Turnera diffusa · Passifloraceae · Leaves (and sometimes stems) · Tea, capsules, tinctures, liquid extracts, dried leaf

An interaction check asks whether these two react with each other — it does not ask whether Damiana is a good idea for someone in your situation. Here is what our Damiana record says about it on its own.

Damiana: dosing

There is no well-established standard dose for damiana. The amount people use varies widely depending on the form—tea, capsule, or tincture.The safest approach is to follow the directions on the product label and not exceed the recommended amount. Because strength differs from product to product, a pharmacist can help you decide whether a particular product and dose make sense for you.If you try damiana, start low, watch how you feel, and stop if you notice side effects.

From our Damiana monograph — the full record covers uses, side effects and every documented interaction.

Read the full Damiana monograph & all interactions
Medication

About Lurasidone

What Is Lurasidone Used For?

Brand name: Latuda

Lurasidone hydrochloride tablets are approved to treat schizophrenia in adults and adolescents aged 13 to 17, and to treat depressive episodes associated with bipolar I disorder (bipolar depression) in adults and children aged 10 to 17. Latuda is one of the brand names under which lurasidone is available as a tablet.

For bipolar depression, lurasidone can be used on its own (monotherapy) in adults and pediatric patients aged 10 to 17, or used alongside lithium or valproate (adjunctive therapy) in adults.

See full Lurasidone drug information
Keep checking

Other Drugs & Damiana

Browse every other medication we’ve checked against Damiana — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Damiana page.

No interaction 2,743 drugs checked — show the list

We also checked Damiana against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Damiana list.

See the full Damiana interactions page
See every supplement checked against Lurasidone, ranked by severity
Evidence & sources

Damiana References

The 2 references that drive our Damiana monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Damiana and Lurasidone Together: Common Questions

Is it safe to take Damiana with Lurasidone?
We do not list a known interaction between Damiana and Lurasidone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Damiana and Lurasidone have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Damiana and Lurasidone at the same time of day?
At least one FDA label for a product containing Lurasidone says to take it with food. If you take Damiana on an empty stomach out of habit, keep them separate and take Lurasidone with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Lurasidone products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Are Damiana and Lurasidone used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Damiana in each. That is a conversation for your prescriber, especially if Lurasidone is being adjusted to a target.
How was the Damiana and Lurasidone combination checked?
Interactions in our licensed database are recorded against drug classes. Lurasidone is filed under 4 classifications, and Damiana has documented interactions with 1 drug class — none of Lurasidone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Damiana interact with any other medications?
Yes. Damiana has 86 documented drug interactions in our database — Lurasidone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Lurasidone interact with any supplements?
Yes. Lurasidone has documented interactions with 149 supplements in our database — Damiana is not one of them. The Lurasidone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Damiana monograph Uses, safety profile, and every drug interaction in one place Lurasidone drug information The full plain-English guide to this medication Lurasidone supplement interactions Every supplement checked against Lurasidone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lurasidone and Damiana?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.