Deanol - Diclegis (Doxylamine Succinate, Pyridoxine Hydrochloride) Interaction
Herbal: Deanol
Also Known As: 2-Dimethyl Aminoethanol, Cyclohexylpropionate de Déanol, Deaner, Deanol Aceglumate, Deanol Acetamidobenzoate, Deanol Benzilate, Deanol Bisorcate, Deanol Cyclohexylpropionate, Deanol Hemisuccinate, Deanol Tartrate, Dimethylaminoethanol, DMAE
Drug: Doxylamine Succinate, Pyridoxine Hydrochloride
Brand names:
Diclegis, Bonjesta
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
Doxylamine Succinate, Pyridoxine Hydrochloride is classified as belonging to the following category: Anticholinergic Drugs
Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.
Interaction Rating
Likelihood of Occurrence
UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
References
- Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
Deanol Overview
Deanol, also known as 2-(dimethylamino)ethanol or DMAE, is a chemical compound that is found naturally in the brain and is also available as a dietary supplement. It is purported to have a number of potential health benefits, including cognitive and mood-enhancing effects.
Deanol is a precursor to choline and is thought to work by increasing the production of acetylcholine, a neurotransmitter that plays a role in memory, learning, and other cognitive functions. It is most often used as a natural remedy for anxiety, depression, and other mental health conditions, although it is important to note that the effectiveness of deanol for these purposes has not been established.
Doxylamine Succinate, Pyridoxine Hydrochloride Overview
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The combination of doxylamine and pyridoxine is used to treat nausea and vomiting in pregnant women whose symptoms have not improved after changing their diet or using other non-medicine treatments. Doxylamine is in a class of medications called antihistamines. It works by blocking the action of certain natural substances in the body that may contribute to nausea and vomiting. Pyridoxine (vitamin B6) is a vitamin. It is given because a lack of pyridoxine in the body may also be a factor in causing nausea and vomiting during pregnancy.
Deanol - More Interactions
Deanol interacts with 216 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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