Fever Bark - Marplan (Isocarboxazid) Interaction

Interaction Details

Isocarboxazid is classified as belonging to the following category: Monoamine Oxidase Inhibitors (Maois)

Concomitant use of MAOIs with fever bark can result in additive effects.
Yohimbine, a constituent of fever bark, has MAO inhibitory effects. At high doses, yohimbine is a non-selective inhibitor of MAO. It is not known if this would occur with fever bark.

Interaction Rating

Likelihood of Occurrence

Well-controlled human studies have demonstrated the likely existence of this interaction

References

• Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
• McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Isocarboxazid Overview

• Isocarboxazid is used to treat depression in people who have not been helped by other antidepressants. Isocarboxazid is in a class of medications called monoamine oxidase (MAO) inhibitors. It works by increasing the amounts of certain natural substances in the brain that help maintain mental balance.

Fever Bark - More Interactions

Fever Bark interacts with 790 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.