Green Tea + Drospirenone, Estetrol
Drospirenone, Estetrol brand name: Nextstellis.
Drospirenone, Estetrol falls into 6 drug categories that Green Tea can interact with; the most serious is rated moderate. Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full interaction reportGreen Tea and Drospirenone, Estetrol
These two interact in 6 distinct ways. Each one is explained separately below.
Why Are There 6 Interactions?
Green Tea interacts with whole categories of medication. Drospirenone, Estetrol falls into 6 of those categories, so it can interact with Green Tea in 6 different ways. We’ve listed each one below — your overall risk is driven by the most serious of them (Moderate).
HEPATOTOXIC DRUGS
1 of 6Why this applies to Drospirenone, Estetrol
Drospirenone, Estetrol falls under HEPATOTOXIC DRUGS — the group Green Tea interacts with.
Green tea extract supplements have been linked to several cases of hepatotoxicity and might have additive hepatotoxic effects with other drugs..
Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans..
Here's the gist with Nextstellis (drospirenone and estetrol) and green tea. This isn't about green tea changing your birth control's hormone levels or making it stronger or weaker. The concern is simply that both can, in rare cases, be tough on the liver. Hormone-based birth control pills carry a small liver risk on their own, and concentrated green tea extract supplements (not your morning cup) have been tied to a handful of liver injury cases too. Stacking two things that may stress the liver is the theoretical worry here.
To be honest, this is graded as unlikely and rests on anecdotal reports, so I wouldn't lose sleep over a normal tea habit. High-dose extracts are the real question. If you notice yellowing skin or eyes, dark urine, belly pain, or unusual fatigue, check in with your doctor. And chat with your pharmacist before starting any green tea supplement.
- Bonkovsky HL. Hepatotoxicity associated with supplements containing Chinese green tea (Camellia sinensis). Ann Intern Med 2006;144:68-71.
- Gloro R, Hourmand-Ollivier I, Mosquet B, et al. Fulminant hepatitis during self-medication with hydroalcoholic extract of green tea. Eur J Gastroenterol Hepatol 2005;17:1135-7. PubMed
- Jimenez-Saenz M, Martinez-Sanchez, MDC. Acute hepatitis associated with the use of green tea infusions. J Hepatol 2006;44:616-9. PubMed
- Javaid, A. and Bonkovsky, H. L. Hepatotoxicity due to extracts of Chinese green tea (Camellia sinensis): a growing concern. J Hepatol 2006;45(2):334-335. PubMed
- Martinez-Sierra, C., Rendon, Unceta P., and Martin, Herrera L. [Acute hepatitis after green tea ingestion]. Med Clin (Barc.) 6-17-2006;127(3):119.
- Molinari, M., Watt, K. D., Kruszyna, T., Nelson, R., Walsh, M., Huang, W. Y., Nashan, B., and Peltekian, K. Acute liver failure induced by green tea extracts: case report and review of the literature. Liver Transpl. 2006;12(12):1892-1895. PubMed
- Federico, A., Tiso, A., and Loguercio, C. A case of hepatotoxicity caused by green tea. Free Radic.Biol Med 8-1-2007;43(3):474. PubMed
- Sarma, D. N., Barrett, M. L., Chavez, M. L., Gardiner, P., Ko, R., Mahady, G. B., Marles, R. J., Pellicore, L. S., Giancaspro, G. I., and Low, Dog T. Safety of green tea extracts : a systematic review by the US Pharmacopeia. Drug Saf 2008;31(6):469-484. PubMed
- Rohde, J., Jacobsen, C., and Kromann-Andersen, H. [Toxic hepatitis triggered by green tea]. Ugeskr.Laeger 1-17-2011;173(3):205-206.
- Yellapu, R. K., Mittal, V., Grewal, P., Fiel, M., and Schiano, T. Acute liver failure caused by 'fat burners' and dietary supplements: a case report and literature review. Can.J.Gastroenterol. 2011;25(3):157-160. PubMed
- Health Canada. Health Product Info Watch. October 2016; 5-6. Available at: http://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/hpiw-ivps_2016-10-eng.php#a15.
- Oketch-Rabah HA, Roe AL, Rider CV, et al. United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts. Toxicol Rep. 2020;7:386-402. PubMed
- Pochet S, Lechon AS, Lescrainier C, et al. Herb-anticancer drug interactions in real life based on VigiBase, the WHO global database. Sci Rep 2022;12(1):14178. PubMed
CYTOCHROME P450 1A2 (CYP1A2) INHIBITORS
2 of 6Drospirenone, Estetrol also falls under CYTOCHROME P450 1A2 (CYP1A2) INHIBITORS.
Green tea contains caffeine. Caffeine is metabolized by cytochrome P450 1A2 (CYP1A2),. Theoretically, drugs that inhibit CYP1A2 may decrease the clearance rate of caffeine from green tea and increase caffeine levels.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's a twist that surprises a lot of people: in this case it's your birth control pill (Nextstellis, which combines drospirenone and estetrol) that may slow down the caffeine in green tea, not the other way around. The estrogen part can gently block a liver enzyme called CYP1A2, which is the main one that clears caffeine. So caffeine may hang around a bit longer than usual.
In real life, that might mean the caffeine from green tea hits you a little harder. Think jitteriness, a racing or pounding heart, trouble sleeping, or feeling wired. This is only a theoretical concern based on how these enzymes work, not strong proof, and an occasional cup is unlikely to cause trouble. If you notice caffeine bothering you more, simply cutting back usually helps. Concentrated green tea extracts are worth running by your pharmacist first.
- Weisburger JH. Tea and health: the underlying mechanisms. Proc Soc Exp Biol Med 1999;220:271-5. PubMed
- Hagg S, Spigset O, Mjorndal T, Dahlqvist R. Effect of caffeine on clozapine pharmacokinetics in healthy volunteers. Br J Clin Pharmacol 2000;49:59-63. PubMed
- Carrillo JA, Benitez J. Clinically significant pharmacokinetic interactions between dietary caffeine and medications. Clin Pharmacokinet 2000;39:127-53. PubMed
- Kot, M. and Daniel, W. A. Effect of diethyldithiocarbamate (DDC) and ticlopidine on CYP1A2 activity and caffeine metabolism: an in vitro comparative study with human cDNA-expressed CYP1A2 and liver microsomes. Pharmacol Rep. 2009;61(6):1216-1220. PubMed
- Wojcikowski, J. and Daniel, W. A. Perazine at therapeutic drug concentrations inhibits human cytochrome P450 isoenzyme 1A2 (CYP1A2) and caffeine metabolism--an in vitro study. Pharmacol Rep. 2009;61(5):851-858. PubMed
- Wang, X. and Yeung, J. H. Effects of the aqueous extract from Salvia miltiorrhiza Bunge on caffeine pharmacokinetics and liver microsomal CYP1A2 activity in humans and rats. J Pharm Pharmacol 2010;62(8):1077-1083.
- Kot M, Daniel WA. Caffeine as a marker substrate for testing cytochrome P450 activity in human and rat. Pharmacol Rep 2008;60:789-97.
- Kjaerstad MB, Nielsen F, Nohr-Jensen L, et al. Systemic uptake of miconazole during vaginal suppository use and effect on CYP1A2 and CYP3A4 associated enzyme activities in women. Eur J Clin Pharmacol 2010;66:1189-97. PubMed
- Goh BC, Reddy NJ, Dandamudi UB, et al. An evaluation of the drug interaction potential of pazopanib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, using a modified Cooperstown 5+1 cocktail in patients with advanced solid t
- Chen Y, Kang Z, Yan J, et al. Liu wei di huang wan, a well-known traditional Chinese medicine induces CYP1A2 while suppressing CYP2A6 and N-acetyltransferase 2 acivities in man. J Ethnopharmacol 2010;132:213-8.
- Suzuki S, Murayama Y, Sugiyama E, et al. Estimating pediatric doses of drugs metabolized by cytochrome P450 (CYP) isozymes, based on physiological liver development and serum protein levels. Yakugaku Zasshi 2010;130:613-20. PubMed
- Chien CF, Wu YT, Lee WC, et al. Herb-drug interaction of Andrographis paniculata extract and andrographolide on the pharmacokinetics of theophylline in rats. Chem Biol Interact 2010;184:458-65. PubMed
- Mills BM, Zaya MJ, Walters RR, et al. Current cytochrome P450 phenotyping methods applied to metabolic drug -drug interaction prediction in dogs. Drug Metab Dispos 2010;38:396-404. PubMed
- Turpault S, Brian W, Van Horn R, et al. Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6, and 3A. Br J Clin Pharmacol 2009;68:928-35. PubMed
- Filimonova AA, Ziganshina LE, Ziganshin AU, Chichirov AA. On the possibility of patient phenotyping on the basis of cytochrome p-450 1A2 isoenzyme activity using caffeine as the test substrate. Eksp Klin Farmakol 2009;72:61-5.
- Jenkins J, Williams D, Deng Y, et al. Eltrombopag, an oral thrombopoietin receptor agonist, has no impact on the pharmacokinetic profile of probe drugs for cytochrome P450 isoenzymes CYP3A4, CYP1A2, CYP2C9 and CYP2C19 in healthy men: a cocktail analysis.
- Perera, V., Gross, A. S., and McLachlan, A. J. Caffeine and paraxanthine HPLC assay for CYP1A2 phenotype assessment using saliva and plasma. Biomed.Chromatogr. 2010;24(10):1136-1144. PubMed
- Izzo, A. A. and Ernst, E. Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs 2009;69(13):1777-1798. PubMed
ESTROGENS
3 of 6Drospirenone, Estetrol also falls under ESTROGENS.
Green tea contains caffeine. Estrogen inhibits caffeine metabolism.
Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..
Here's a twist worth knowing: this interaction isn't really about your birth control getting weaker or stronger. It runs the other direction. The estrogen part of Nextstellis (estetrol) can slow down how your body clears caffeine, and green tea naturally contains caffeine. So the caffeine from your tea may hang around longer than usual.
In plain terms, you might feel more of caffeine's usual effects: a little jittery, a racing or pounding heart, trouble sleeping, or an uneasy stomach. This is mostly a concern with regular tea drinking, and a single cup probably won't be a big deal for most people. If you notice you're more sensitive to caffeine than before, ease up a bit or chat with your pharmacist. Nothing here means you should stop your pill.
- Pollock BG, Wylie M, Stack JA, et al. Inhibition of caffeine metabolism by estrogen replacement therapy in postmenopausal women. J Clin Pharmacol 1999;39:936-40. PubMed
P-GLYCOPROTEIN SUBSTRATES
4 of 6Drospirenone, Estetrol also falls under P-GLYCOPROTEIN SUBSTRATES.
In vitro research and case reports suggest that green tea inhibits drug efflux by P-gp, potentially increasing serum levels of P-gp substrates. Case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking green tea and certain P-gp substrates.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's the gist for your Nextstellis (drospirenone and estetrol) birth control pill. There's a small body of evidence that green tea can block a transporter called P-glycoprotein, which acts like a pump that helps move certain medicines out of your body. If that pump slows down, a bit more of the hormone could stay in your system. In theory, that might nudge up the usual hormone side effects, things like breast tenderness, nausea, bloating, headache, or mood changes.
Honestly though, this is based on lab studies and scattered case reports, not solid trials, so it's a weak signal. A normal cup or two of green tea is very unlikely to cause trouble. Concentrated green tea extract pills are more of a question mark. If you take those regularly, just run it by your pharmacist or doctor.
- Pochet S, Lechon AS, Lescrainier C, et al. Herb-anticancer drug interactions in real life based on VigiBase, the WHO global database. Sci Rep 2022;12(1):14178. PubMed
CONTRACEPTIVE DRUGS
5 of 6Drospirenone, Estetrol also falls under CONTRACEPTIVE DRUGS.
Green tea contains caffeine. Oral contraceptives can decrease caffeine clearance by 40% to 65%.
Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..
Here's a fun twist with this pairing: it's not your Nextstellis (drospirenone/estetrol) that gets thrown off, it's the caffeine in the green tea. Birth control pills like this one can slow down how fast your body clears caffeine, sometimes by 40% to 65%. So the cup of green tea you've always tolerated may now hit a little harder and stick around longer.
In real life that can mean feeling more jittery, a racing heart, trouble sleeping, or an upset stomach. This is mostly a concern with concentrated green tea extracts or several strong cups a day, not a single light cup. Your contraceptive still works the same. If you notice these effects, just ease back on the caffeine and mention it to your pharmacist or doctor.
- Haller CA, Jacob P 3rd, Benowitz NL. Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use. Clin Pharmacol Ther 2002;71:421-32. PubMed
CYTOCHROME P450 3A4 (CYP3A4) SUBSTRATES
6 of 6Drospirenone, Estetrol also falls under CYTOCHROME P450 3A4 (CYP3A4) SUBSTRATES.
In vitro and in vivo research suggests that green tea can inhibit intestinal CYP3A and induce hepatic CYP3A4 enzymes. However, this effect is unlikely to be clinically significant, as green tea does not appear to affect CYP3A4 activity in humans.
Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans..
Good news here: your birth control pill Nextstellis (drospirenone with estetrol) is partly processed by a liver enzyme called CYP3A4, and green tea can tug on that enzyme a little in lab tests. But the key word is lab. In actual people, drinking green tea doesn't seem to meaningfully change how this enzyme works, so it's very unlikely to weaken your pill or make side effects worse.
In plain terms, enjoying your usual cups of green tea shouldn't affect how well Nextstellis prevents pregnancy or cause new issues like breast tenderness or breakthrough bleeding. If you're thinking about concentrated green tea extract pills rather than the drink, just run that by your pharmacist first.
- Donovan JL, Chavin KD, Devane CL, et al. Green tea (Camellia sinensis) extract does not alter cytochrome P450 3A4 or 2D6 activity in healthy volunteers. Drug Metab Dispos 2004;32:906-8. PubMed
- Nishikawa, M., Ariyoshi, N., Kotani, A., Ishii, I., Nakamura, H., Nakasa, H., Ida, M., Nakamura, H., Kimura, N., Kimura, M., Hasegawa, A., Kusu, F., Ohmori, S., Nakazawa, K., and Kitada, M. Effects of continuous ingestion of green tea or grape seed extrac
- Chow, H. H., Hakim, I. A., Vining, D. R., Crowell, J. A., Cordova, C. A., Chew, W. M., Xu, M. J., Hsu, C. H., Ranger-Moore, J., and Alberts, D. S. Effects of repeated green tea catechin administration on human cytochrome P450 activity. Cancer Epidemiol.B PubMed
- Engdal, S. and Nilsen, O. G. In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients. Phytother.Res. 2009;23(7):906-912.
- Schönthal AH. Adverse effects of concentrated green tea extracts. Mol Nutr Food Res. 2011 Jun;55(6):874-85. PubMed
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Green Tea Also Interacts With Other Medications
Green Tea has 13 major, 904 moderate, 375 minor known drug interactions in our database — the Drospirenone, Estetrol one above is among them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Green Tea
We haven’t checked that one against Green Tea yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Green Tea. Pick one to open its full report.
Questions About Green Tea or Drospirenone, Estetrol
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Green Tea or Drospirenone, Estetrol, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Drospirenone, Estetrol
This page covers Green Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Drospirenone, Estetrol page lists 245 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).
By severity: 6 major · 200 moderate · 39 minor.
From our pharmacist’s overview on the Drospirenone, Estetrol page
“The stakes with Nextstellis (drospirenone and estetrol) are the ones that come with any birth control pill, because an interaction that lowers its hormone levels can mean an unplanned pregnancy, and I would treat this list with genuine seriousness. Most of what is here changes how the body handles the hormones.”
Reviewed by 2 · Jul 18, 2026
Taking Green Tea as Part of a Dietary Supplement Product? Check It for Interactions
We hold 9,084 real supplement products containing Green Tea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Green Tea. Your product may carry other ingredients that interact with Drospirenone, Estetrol too, on top of Green Tea — and those would not show on this page. Find your product and we’ll check every ingredient on its label:
Where Green Tea and Drospirenone, Estetrol Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#27 of 1,452 supplements looked up here in the last 7 days
#934 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Green Tea
What is Green Tea?
- Antioxidant support
- Weight loss
- Heart health
- Mental alertness
- Cancer risk reduction
Green tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people. Concentrated green tea extracts are a different story—they may help modestly with weight or heart health for some, but high doses have been linked to rare liver problems. Talk to your pharmacist or doctor before taking green tea supplements, especially if you have liver concerns or are pregnant.
Other Drugs & Green Tea
Browse every other medication we’ve checked against Green Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
13 interactions
- Nadolol ›
- Atorvastatin ›
- Atorvastatin Calcium ›
- Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate ›
- Ephedrine, Guaifenesin (otc Drug) ›
- Ephedrine, Hydroxyzine, Theophylline ›
- Ephedrine, Phenobarbital, Potassium Iodide, Theophylline ›
- Aminophylline, Amobarbital, Ephedrine ›
- Bendroflumethiazide, Nadolol ›
- Dyphylline, Ephedrine, Guaifenesin, Phenobarbital ›
- Ephedrine, Guaifenesin, Phenobarbital, Theophylline ›
- Ephedrine, Phenobarbital, Theophylline ›
- Ezetimibe, Atorvastatin ›
904 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Theophylline ›
- Nifedipine ›
- Ibuprofen ›
- Salbutamol Sulfate ›
- Phentermine ›
- Aspirin ›
- Hydrocortisone ›
- Methylphenidate ›
- Naproxen ›
- Doxycycline ›
- Erythromycin ›
- Estradiol ›
- Minocycline ›
- Tetracycline ›
- Ranitidine ›
- Amoxicillin ›
- Hydrochlorothiazide ›
- Norethindrone ›
- Testosterone ›
- Verapamil ›
- Fenofibrate ›
- Levonorgestrel ›
- Phenylpropanolamine ›
- Prednisone ›
- Quinidine ›
- Cyclosporine ›
- Dexamethasone ›
- Glyburide ›
- Methyltestosterone ›
- Ciprofloxacin ›
- Colchicine ›
- Nicotine ›
- Phenytoin ›
- Prednisolone ›
- Triamcinolone ›
- Allopurinol ›
- Apomorphine ›
- Carbamazepine ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Doxorubicin ›
- Morphine Sulfate ›
- Phenylephrine ›
- Pseudoephedrine ›
- Acetaminophen ›
- Albuterol ›
- Amphetamine ›
- Conjugated Estrogens ›
- Diethylpropion ›
- Everolimus ›
- Ivermectin ›
- Ketoprofen ›
- Methotrexate ›
- Nitrofurantoin ›
- Ofloxacin ›
- Propoxyphene ›
- Rifampin ›
- Selegiline ›
Showing 60 of 904 moderate interactions — see all 904 on the Green Tea page.
375 interactions
- Insulin (rdna) ›
- Lidocaine ›
- Insulin (pork) ›
- Triazolam ›
- Zopiclone ›
- Fentanyl ›
- Oxybutynin ›
- Tacrolimus ›
- Temazepam ›
- Budesonide ›
- Clindamycin ›
- Dextromethorphan ›
- Fluticasone ›
- Insulin (human) ›
- Miconazole ›
- Buprenorphine ›
- Diazepam ›
- Ivabradine ›
- Medroxyprogesterone ›
- Medroxyprogesterone Acetate ›
- Aripiprazole ›
- Ciclesonide ›
- Clonazepam ›
- Cyclobenzaprine ›
- Fluphenazine ›
- Fluticasone Propionate ›
- Hydroxyzine ›
- Insulin Glargine ›
- Midazolam ›
- Nicardipine ›
- Pantoprazole ›
- Progesterone (prescription Drug) ›
- Semaglutide ›
- Tramadol ›
- Zolpidem ›
- Almotriptan ›
- Alprazolam ›
- Aprepitant ›
- Aripiprazole Lauroxil ›
- Budenoside ›
- Buprenorphine Hydrochloride ›
- Busulfan ›
- Cabazitaxel ›
- Chlorpheniramine ›
- Chlorpromazine ›
- Clomipramine ›
- Dasatinib ›
- Dexchlorpheniramine ›
- Dihydroergotamine ›
- Disopyramide Phosphate ›
- Dronabinol ›
- Ergotamine Tartrate (prescription Drug) ›
- Exenatide ›
- Felodipine ›
- Finasteride ›
- Fluticasone Furoate ›
- Fosamprenavir ›
- Fosaprepitant ›
- Galantamine ›
- Glipizide ›
Showing 60 of 375 minor interactions — see all 375 on the Green Tea page.
No interaction 1,537 drugs checked — show the list
We also checked Green Tea against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Metoprolol ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Propranolol ›
- Bupropion ›
- Bendamustine ›
- Acyclovir ›
- Fluoxetine ›
- Lamotrigine ›
- Pregabalin ›
- Azithromycin ›
- Gabapentin ›
- Isotretinoin ›
- Methylene Blue ›
- Bisoprolol ›
- Levothyroxine, Liothyronine ›
- Candesartan Cilexetil ›
- Cephalexin ›
- Cyclopentolate ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Roxithromycin ›
- Pegunigalsidase Alfa-iwxj ›
- Levetiracetam ›
- Daptomycin ›
- Ezetimibe ›
- Levothyroxine Sodium ›
- Valsartan ›
- Hexobarbitone ›
- Phentermine, Topiramate ›
- Thyroid Hormone ›
- Carbidopa, Levodopa ›
- Factor 7a ›
- Levodopa ›
- Mitomycin ›
- Minoxidil ›
- Cefaclor ›
- Venlafaxine ›
- Azelaic Acid ›
- Codeine Sulfate ›
- Nortriptyline ›
- Hydroxychloroquine ›
- Dirithromycin ›
- Vancomycin ›
- Pizotifen ›
- Bentoquatam ›
- Triptorelin ›
- Procainamide ›
- Dextrothyroxine ›
- Tocainide ›
- Ropinirole ›
- Rocuronium ›
- Telmisartan ›
- Mitomycin C ›
- Flecainide ›
- Digitoxin ›
- Lomustine ›
- Chenodiol ›
Showing the 60 most looked-up of 1,537 medications checked with no known interaction — see the full Green Tea list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drospirenone, Estetrol Is Linked to Lower Levels of 7 Nutrients
Natural Medicines records Drospirenone, Estetrol as a medicine that can lower these. This is not an interaction with Green Tea — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Drospirenone, Estetrol nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Green Tea and Drospirenone, Estetrol Together: Common Questions
Can you take Green Tea with Drospirenone, Estetrol?
Why are there 6 interactions listed for Green Tea and Drospirenone, Estetrol?
How serious is the Green Tea and Drospirenone, Estetrol interaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Still Have a Question About Drospirenone, Estetrol and Green Tea?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.