Drug & supplement interaction

Padang Cassia + Colestipol

Colestipol brand name: Colestid.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Padang Cassia and Colestipol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Colestipol states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Padang Cassia and Colestipol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Colestipol and Padang Cassia in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Padang Cassia safety at a glance

Padang Cassia overall Use caution Generally safe as a food spice, but cassia cinnamons contain coumarin that may harm the liver in large or long-term supplement doses.
Pregnancy Use caution Food amounts are likely fine, but avoid concentrated supplement doses during pregnancy without medical advice.
Breastfeeding Use caution Food amounts are likely fine, but there is little safety data on supplement-level doses while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Colestipol and Padang Cassia? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Colestipol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Colestipol is filed under 2 classifications — bile acid sequestrants, oral drugs. Padang Cassia has documented interactions with 3 drug classes — the most serious being antidiabetes drugs (moderate), cytochrome p450 3a4 (cyp3a4) substrates (moderate) and hepatotoxic drugs (moderate) — and none of Colestipol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Padang Cassia Does Interact With Other Medications

Padang Cassia has 934 moderate known drug interactions in our database — Colestipol isn’t one of them. If you take anything else, check it against the full list below.

Moderate 934 No known interaction 1,896 (incl. Colestipol)
Taking anything else?

Check Another of Your Medications Against Padang Cassia

Covers the 2,830 medications we’ve checked against Padang Cassia. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Padang Cassia and Colestipol May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A fast or pounding heartbeat / Stomach upset Additional detail

    Padang Cassia

    “Orally, Padang cassia appears to be well tolerated. No adverse effects have been reported in clinical trials when Padang cassia is used alone. When Padang cassia extract is used with banaba leaf extract in a specific combination product (Inlacin, Dexa Medica), adverse effects reported in clinical trials have included dizziness, headache, tremor, palpitations, weakness, diaphoresis, and stomach upset.”

    Padang Cassia · Natural Medicines adverse-effect record, reported in cirrhosis.

    6 sources cited
    1. 93117. Kort DH, Lobo RA. Preliminary evidence that cinnamon improves menstrual cyclicity in women with polycystic ovary syndrome: a randomized controlled trial. Am J Obstet Gynecol 2014;211(5):487.e1-6. PubMed
    2. 93147. Ziegenfuss TN, Hofheins JE, Mendel RW, et al. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr 2006;3:45-53. PubMed
    3. 92848. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
    4. 92849. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple
    5. 93121. Wang R, Wang R, Yan B. Extraction of essential oils from five cinnamon leaves and identification of their volatile compound compositions. Innovative Food Science and Emerging Technologies 2009;10:289-92. DOI
    6. 93122. Wang YH, Avula B, Nanayakkara NP, et al. Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States. J Agric Food Chem 2013;61(18):4470-6. PubMed

    Colestipol

    Listed in the ADVERSE REACTIONS section of the FDA label for Colestipol. Read the label on DailyMed ›

  • Dizziness / Headache Additional detail

    Padang Cassia

    “Orally, a specific product containing extracts of Padang cassia and banaba leaf (Inlacin, Dexa Medica) has been reported to cause dizziness, headache, tremor, and weakness. However, it is unclear if these adverse effects were caused by Padang cassia extract, banaba leaf extract, or the combination.”

    Padang Cassia · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 92848. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
    2. 92849. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple

    Colestipol

    Listed in the ADVERSE REACTIONS section of the FDA label for Colestipol. Read the label on DailyMed ›

Reported for Padang Cassia but not commonly for Colestipol: liver problems, sweating and tremor or shakiness.

Effects for Colestipol come from the ADVERSE REACTIONS section of its FDA label; effects for Padang Cassia come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Colestipol Products Have a Food Rule — Padang Cassia Should Not Break It

At least one FDA label for a product containing Colestipol says to take it on an empty stomach. Most supplements — Padang Cassia included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Colestipol on its own and move Padang Cassia to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Colestipol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Patients should take other drugs at least one hour before or four hours after colestipol hydrochloride tablets to minimize possible interference with their absorption.

From the Dosage and Administration section of the FDA label we read for Colestipol — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Padang Cassia or Colestipol

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Padang Cassia or Colestipol, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Colestipol

This page covers Padang Cassia only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Colestipol page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 8 moderate · 9 minor.

From our pharmacist’s overview on the Colestipol page

“Take colestipol (Colestid), a cholesterol drug that works by trapping bile acids in your gut, and nearly every one of the 18 supplement interactions on file comes down to absorption. Only one rates major, activated charcoal, and it belongs at the top of your reading.”

Reviewed by 2 · Jul 18, 2026

Open the Colestipol interaction page

How much people look this up

Where Padang Cassia and Colestipol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Padang Cassia
Steady interest

#816 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Colestipol
Steady interest

#1,991 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Padang Cassia reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Padang Cassia and Colestipol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Padang Cassia

What is Padang Cassia?

  • Adding flavor to food
  • Digestive upset
  • Blood sugar support
  • Antimicrobial purposes
  • Antioxidant support

Padang Cassia is a type of cinnamon (Indonesian or Korintje cinnamon) grown mainly in Indonesia and used widely as a kitchen spice. As a supplement, evidence for health benefits like blood sugar control is limited and mixed, and like other cassia cinnamons it naturally contains coumarin, which can be harmful to the liver in large amounts. Use food amounts freely, but talk to a pharmacist or doctor before taking concentrated cinnamon supplements.

Cinnamomum burmannii · Lauraceae · Inner bark (and bark-derived essential oil) · Ground spice, dried bark sticks (quills), capsules, powder, extract, essential oil, tea

An interaction check asks whether these two react with each other — it does not ask whether Padang Cassia is a good idea for someone in your situation. Here is what our Padang Cassia record says about it on its own.

Padang Cassia: dosing

There is no official, standardized dose of Padang Cassia for any health condition. Amounts used in studies vary widely and are not specific to this species.If you choose to use a cinnamon supplement, follow the directions on the product label and do not exceed the recommended amount. Because cassia cinnamons are higher in coumarin, it is wise to keep concentrated supplement doses low and to avoid taking them every day for long periods.Using Padang Cassia as a normal cooking spice is a low-risk way to enjoy it.

From our Padang Cassia monograph — the full record covers uses, side effects and every documented interaction.

Read the full Padang Cassia monograph & all interactions
Medication

About Colestipol

What Is Colestipol Used For?

Brand name: Colestid

Colestipol — available as oral suspension and tablets under brands including Colestid, Flavored Colestid, and Colestipol Hydrochloride — is used as part of a broader treatment plan (including diet) to lower elevated LDL cholesterol in adults with primary hypercholesterolemia (a condition where LDL cholesterol stays high despite dietary changes).

It is not a standalone fix. Diet, weight management, and other lifestyle changes come first, and colestipol is added when those steps alone aren't enough to reach target LDL levels.

See full Colestipol drug information
Keep checking

Other Drugs & Padang Cassia

Browse every other medication we’ve checked against Padang Cassia — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
934Moderate
0Minor
1,895No known interaction
934 Moderate 1,895 No interaction
Moderate

934 interactions

Showing 60 of 934 moderate interactions — see all 934 on the Padang Cassia page.

No interaction 1,895 drugs checked — show the list

We also checked Padang Cassia against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,895 medications checked with no known interaction — see the full Padang Cassia list.

See the full Padang Cassia interactions page
See every supplement checked against Colestipol, ranked by severity
Evidence & sources

Padang Cassia References

The 14 references that drive our Padang Cassia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  2. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  3. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  4. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
  5. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple
  6. Kort DH, Lobo RA. Preliminary evidence that cinnamon improves menstrual cyclicity in women with polycystic ovary syndrome: a randomized controlled trial. Am J Obstet Gynecol 2014;211(5):487.e1-6. PubMed
  7. Roussel AM, Hininger I, Benaraba R, et al. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr 2009;28(1):16-21. PubMed
  8. Wang R, Wang R, Yan B. Extraction of essential oils from five cinnamon leaves and identification of their volatile compound compositions. Innovative Food Science and Emerging Technologies 2009;10:289-92. DOI
  9. Wang YH, Avula B, Nanayakkara NP, et al. Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States. J Agric Food Chem 2013;61(18):4470-6. PubMed
  10. Woehrlin F, Fry H, Abraham K, Preiss-Weigert A. Quantification of flavoring constituents in cinnamon: high variation of coumarin in cassia bark from the German retail market and in authentic samples from Indonesia. J Agric Food Chem 2010;58(19):10568-75. PubMed
  11. Subehan S, Kadota S, Tezuka Y. In vitro mechanism-based inactivation of cytochrome P450 3A4 by a new constituent of Cinnamomum burmani. Planta Med 2008;74(12):1474-80.
  12. Bernardo MA, Silva ML, Santos E, et al. Effect of cinnamon tea on postprandial glucose concentration. J Diabetes Res 2015;2015:913651. PubMed
  13. Ziegenfuss TN, Hofheins JE, Mendel RW, et al. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr 2006;3:45-53. PubMed
  14. Shishehbor F, Rezaeyan Safar M, Rajaei E, Haghighizadeh MH. Cinnamon consumption improves clinical symptoms and inflammatory markers in women with rheumatoid arthritis. J. Am. Coll. Nutr. 2018. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Padang Cassia and Colestipol Together: Common Questions

Is it safe to take Padang Cassia with Colestipol?
We do not list a known interaction between Padang Cassia and Colestipol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Padang Cassia and Colestipol have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Padang Cassia and Colestipol at the same time of day?
At least one FDA label for a product containing Colestipol says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Colestipol on its own and move Padang Cassia to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
How was the Padang Cassia and Colestipol combination checked?
Interactions in our licensed database are recorded against drug classes. Colestipol is filed under 2 classifications, and Padang Cassia has documented interactions with 3 drug classes — none of Colestipol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Padang Cassia interact with any other medications?
Yes. Padang Cassia has 934 documented drug interactions in our database — Colestipol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Colestipol interact with any supplements?
Yes. Colestipol has documented interactions with 18 supplements in our database — Padang Cassia is not one of them. The Colestipol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Padang Cassia monograph Uses, safety profile, and every drug interaction in one place Colestipol drug information The full plain-English guide to this medication Colestipol supplement interactions Every supplement checked against Colestipol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 14 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Colestipol and Padang Cassia?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.