Vinpocetine - Kisqali (Ribociclib Succinate) Interaction
Herbal: Vinpocetine
Also Known As: Eburnamenine-14-carboxylic acid, AY-27255, Cavinton, Common Periwinkle Extract, Common Periwinkle Vinpocetine, Eburnamenine-14-Carboxylic Acid, Ethyl Apovincaminate, Ethylapovincaminoate, Lesser Periwinkle Extract, RGH-4405, TCV-3b, Vinca Minor Extract, Vinpocetin, Vi
Drug: Ribociclib Succinate
Brand names:
Kisqali
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
There were no interactions found between Ribociclib Succinate and Vinpocetine. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Vinpocetine Overview
Vinpocetine is a synthetic compound that is derived from the alkaloid vincamine, which is found in the periwinkle plant (Vinca minor). It is used as a dietary supplement and is claimed to have a number of potential health benefits, including improving memory and cognitive function, increasing blood flow to the brain, and reducing inflammation. The Food and Drug Administration (FDA), in 2019, issued a warning that those who are pregnant or who could become pregnant should avoid vinpocetine due to safety concerns.
Ribociclib Succinate Overview
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Ribociclib is used in combination with another medication to treat a certain type of hormone receptor–positive (depends on hormones such as estrogen to grow) advanced breast cancer or that has spread to other parts of the body in women who have not experienced menopause (change of life; end of monthly menstrual periods) and in those who are close to or who have already experienced menopause. Ribociclib is also used in combination with fulvestrant (Faslodex) to treat a certain type of hormone receptor–positive advanced breast cancer or that has spread to other parts of the body as an initial treatment or in people who have not been treated successfully with other treatments in women who have already experienced menopause. Ribociclib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.
Vinpocetine - More Interactions
Vinpocetine interacts with 205 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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