Medication interaction hub

What Supplements Interact with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Brompheniramine, Phenylephrine, Phenylpropanolamine brand names: Normatane TD, Dime Time. Every interaction below applies to the brands too.

87 Interactions 5 Major 68 Moderate 14 Minor
Curated & coded by · Clinical Pharmacist · Updated September 16, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Brompheniramine, Phenylephrine, Phenylpropanolamine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Brompheniramine, Phenylephrine, Phenylpropanolamine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Anyone taking Normatane TD (brompheniramine, phenylephrine, phenylpropanolamine) for congestion is often also holding a coffee or an energy drink, and that pairing is exactly the problem. This list warrants real caution. Of its 87 supplement ingredients, 44 add stimulant load on top of the decongestants already in the medicine, raising the risk of high blood pressure and other heart effects. Ephedra and Sida cordifolia sit among the five major-rated entries, and everyday caffeine sources like tea and cocoa fall in the moderate column.

The rest mostly covers two quieter problems: 20 ingredients that add sun sensitivity, and 17 that can blunt absorption of anything swallowed, with activated charcoal rated major there and best spaced well apart from your dose. Against 68 moderates and 14 minors, every one of the five majors involves either a stimulant plant or something that keeps the medicine from being absorbed, which tells you where to look first.

— , Clinical Pharmacist · July 18, 2026

Major 5 Moderate 68 Minor 14 No known interaction 1,365

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Brompheniramine, Phenylephrine, Phenylpropanolamine: Top Interactions at a Glance

The most significant Brompheniramine, Phenylephrine, Phenylpropanolamine supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 87 interacting ingredients — plus 1,365 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Brompheniramine, Phenylephrine, Phenylpropanolamine + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Activated Charcoal + Brompheniramine, Phenylephrine, Phenylpropanolaminei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Ephedra + Brompheniramine, Phenylephrine, Phenylpropanolaminei

Theoretically, concomitant use might increase the risk for serious adverse effects.

Read the full interaction Major Likelihood Probable Peyote + Brompheniramine, Phenylephrine, Phenylpropanolaminei

Concomitant use of peyote with stimulant drugs may increase the risk of adverse CNS effects.

Read the full interaction Major Likelihood Probable Rauvolfia Vomitoria + Brompheniramine, Phenylephrine, Phenylpropanolaminei

Theoretically, concomitant use might cause additive effects.

Read the full interaction Major Likelihood Probable Sida Cordifolia + Brompheniramine, Phenylephrine, Phenylpropanolaminei

Theoretically, Sida cordifolia might increase the risk of adverse cardiovascular effects when taken with stimulant drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Brompheniramine, Phenylephrine, Phenylpropanolamine

All 1,452 ingredients in our database, ranked by severity — 87 with a Brompheniramine, Phenylephrine, Phenylpropanolamine interaction on file and 1,365 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Brompheniramine, Phenylephrine, Phenylpropanolamine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Yerba Mate with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of stimulant drugs and yerba mate might increase stimulant adverse effects.

Full Yerba Mate + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take 1,3-dmaa with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. 1,3-DMAA is thought to have stimulant effects.

Full 1,3-dmaa + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take 1,3-dmba with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining 1,3-DMBA with other stimulant drugs might increase the risk of cardiovascular toxicity.

Full 1,3-dmba + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take 1,4-dmaa with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. 1,4-DMAA is thought to have stimulant and vasoconstrictive effects, which have been demonstrated in animal studies.

Full 1,4-dmaa + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Acacia Rigidula with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Acacia rigidula with stimulant drugs might increase the risk of adverse cardiovascular effects.

Full Acacia Rigidula + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Aconite with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining aconite with other stimulant drugs might alter the effects of the stimulant drug or increase the risk of cardiovasc...

Full Aconite + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Adrafinil with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking adrafinil with stimulant drugs might have additive stimulant effects.

Full Adrafinil + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Alfalfa with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Full Alfalfa + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Angelica Archangelica with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Angelica archangelica, whether ingested or applied to the skin, has the potential to induce photosensitivity reactions.

Full Angelica Archangelica + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Arrach with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of arrach can increase risk of adverse effects, as unspecified Chenopodium species are associated with photos...

Full Arrach + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Beta-methylphenethylamine (bmpea) with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking BMPEA with other stimulant drugs might increase the risk of adverse cardiovascular effects.

Full Beta-methylphenethylamine (bmpea) + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Biofeedback with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.

Full Biofeedback + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Bishop's Weed with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bishop's weed constituents seem to cause photosensitivity.

Full Bishop's Weed + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Bitter Orange with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, bitter orange might increase the risk of hypertension and adverse cardiovascular effects when taken with stimulant drugs.

Full Bitter Orange + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Butcher's Broom with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, butcher's broom might increase the effects and adverse effects of alpha-adrenergic agonists.

Full Butcher's Broom + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Chlorella with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chlorella might have additive effects with photosensitizing drugs.

Full Chlorella + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Cilantro with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that coriandrin, a constituent of cilantro, has photosensitizing effects.

Full Cilantro + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Coriander with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.

Full Coriander + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Dendrobium with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The dendrobium constituent dendrobine is reported to have convulsant effects.

Full Dendrobium + Brompheniramine, Phenylephrine, Phenylpropanolamine answer

Can you take Dimethylhexylamine (dmha) with Brompheniramine, Phenylephrine, Phenylpropanolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining DMHA with stimulant drugs might increase the risk of adverse cardiovascular effects.

Full Dimethylhexylamine (dmha) + Brompheniramine, Phenylephrine, Phenylpropanolamine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Brompheniramine, Phenylephrine, Phenylpropanolamine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Brompheniramine, Phenylephrine, Phenylpropanolamine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Brompheniramine, Phenylephrine, Phenylpropanolamine sits in 6 interaction categories. Open any one to see what the group means:

Stimulant Drugs 44 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

44 of the supplement ingredients on this page reach Brompheniramine, Phenylephrine, Phenylpropanolamine through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Brompheniramine, Phenylephrine, Phenylpropanolamine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Brompheniramine, Phenylephrine, Phenylpropanolamine through this category.

Phenylpropanolamine 12 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

12 of the supplement ingredients on this page reach Brompheniramine, Phenylephrine, Phenylpropanolamine through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Brompheniramine, Phenylephrine, Phenylpropanolamine through this category.

Alpha-Adrenergic Agonists 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Brompheniramine, Phenylephrine, Phenylpropanolamine through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Brompheniramine, Phenylephrine, Phenylpropanolamine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Brompheniramine, Phenylephrine, Phenylpropanolamine.

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Pharmacist Counseling Corner

Brompheniramine, Phenylephrine, Phenylpropanolamine & Supplements: Common Questions

What supplements interact with Brompheniramine, Phenylephrine, Phenylpropanolamine?
More than you might expect — 87 in total, though they are far from equal: 5 are rated major, 68 moderate, and 14 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Activated Charcoal, Ephedra, Peyote.
Which Brompheniramine, Phenylephrine, Phenylpropanolamine supplement interactions are the most serious?
The 5 major-rated combinations — led by Activated Charcoal, Ephedra, Peyote, Rauvolfia Vomitoria and Sida Cordifolia — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Brompheniramine, Phenylephrine, Phenylpropanolamine?
Usually yes — most people on Brompheniramine, Phenylephrine, Phenylpropanolamine can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Normatane TD have the same supplement interactions as Brompheniramine, Phenylephrine, Phenylpropanolamine?
Yes — Normatane TD, Dime Time all contain Brompheniramine, Phenylephrine, Phenylpropanolamine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Brompheniramine, Phenylephrine, Phenylpropanolamine and my other medications?
This page covers Brompheniramine, Phenylephrine, Phenylpropanolamine against supplements and herbal ingredients. Checking Brompheniramine, Phenylephrine, Phenylpropanolamine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 16, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.