Medication interaction hub

What Supplements Interact with Golimumab?

Golimumab brand name: Simponi Aria. Every interaction below applies to the brands too.

53 Interactions 52 Moderate 1 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Golimumab? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Golimumab against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Echinacea is the entry I would flag first, since it is the immune booster people reach for at the first sniffle, and immune stimulation is exactly what golimumab (Simponi Aria) is designed to dial down. Golimumab blocks TNF to quiet inflammation in conditions like rheumatoid arthritis and ulcerative colitis, and all 53 supplements on this list are here for the same reason. Each may rev up immune activity and work against the drug. None is rated major, 52 are moderate and one is minor, so this is a list to watch rather than fear.

Much of the evidence is lab or animal research, which means the concern is theoretical for many entries. Still, popular products such as ashwagandha and astragalus sit in the same bucket as echinacea. If your joints or gut flare while you are taking one of these, the supplement deserves a hard look before you blame the drug.

— , Clinical Pharmacist · July 18, 2026

Moderate 52 Minor 1 No known interaction 1,399

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Golimumab: Top Interactions at a Glance

The most significant Golimumab supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 53 interacting ingredients — plus 1,399 more checked with no known interaction. See the complete ranked list.

Start here

The Moderate Interactions to Know About

The most clinically significant Golimumab + supplement combinations in our database, best-documented first. Open any card for the full report.

Moderate Likelihood Possible Active Hexose Correlated Compound (ahcc) + Golimumabi

Theoretically, taking AHCC might decrease the effects of immunosuppressant drugs.

Read the full interaction Moderate Likelihood Possible Alfalfa + Golimumabi

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.

Read the full interaction Moderate Likelihood Possible American Ginseng + Golimumabi

Theoretically, American ginseng use might interfere with immunosuppressive therapy.

Read the full interaction Moderate Likelihood Possible Andrographis + Golimumabi

Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.

Read the full interaction Moderate Likelihood Possible Ashwagandha + Golimumabi

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.

Read the full interaction Moderate Likelihood Possible Astragalus + Golimumabi

Theoretically, astragalus might interfere with immunosuppressive therapy.

Read the full interaction
The complete list

Every Supplement Checked Against Golimumab

All 1,452 ingredients in our database, ranked by severity — 53 with a Golimumab interaction on file and 1,399 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Golimumab?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Cat's Claw with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cat's claw might interfere with immunosuppressive therapy.

Full Cat's Claw + Golimumab answer

Can you take Shark Cartilage with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, shark cartilage might interfere with immunosuppressive therapy.

Full Shark Cartilage + Golimumab answer

Can you take Shiitake Mushroom with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.

Full Shiitake Mushroom + Golimumab answer

Can you take Thuja with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Thuja might stimulate immune function.

Full Thuja + Golimumab answer

Can you take Thunder God Vine with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, thunder god vine might enhance the effects of immunosuppressant drugs.

Full Thunder God Vine + Golimumab answer

Can you take Thymus Extract with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, patients taking immunosuppressants may be at an increased risk of infection from contaminated thymus extract.

Full Thymus Extract + Golimumab answer

Can you take Tinospora Cordifolia with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.

Full Tinospora Cordifolia + Golimumab answer

Can you take Trichopus Zeylanicus with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Trichopus zeylanicus might reduce the effects of immunosuppressants.

Full Trichopus Zeylanicus + Golimumab answer

Can you take Umckaloabo with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Pelargonium sidoides might decrease the effectiveness of immunosuppressant therapy.

Full Umckaloabo + Golimumab answer

Can you take Lychee with Golimumab?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, lychee might reduce the effectiveness of immunosuppressant drugs.

Full Lychee + Golimumab answer

Can you take Active Hexose Correlated Compound (ahcc) with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking AHCC might decrease the effects of immunosuppressant drugs.

Full Active Hexose Correlated Compound (ahcc) + Golimumab answer

Can you take Alfalfa with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.

Full Alfalfa + Golimumab answer

Can you take American Ginseng with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, American ginseng use might interfere with immunosuppressive therapy.

Full American Ginseng + Golimumab answer

Can you take Andrographis with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.

Full Andrographis + Golimumab answer

Can you take Ashwagandha with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.

Full Ashwagandha + Golimumab answer

Can you take Astragalus with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, astragalus might interfere with immunosuppressive therapy.

Full Astragalus + Golimumab answer

Can you take Bee Venom with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bee venom might stimulate immune system activity.Theoretically, bee venom might interfere with immunosuppressant therapy.

Full Bee Venom + Golimumab answer

Can you take Beta-glucans with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, beta-glucans might interfere with immunosuppressive therapy.

Full Beta-glucans + Golimumab answer

Can you take Black Hoof Mushroom with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black hoof mushroom might reduce the effects of immunosuppressant medications.

Full Black Hoof Mushroom + Golimumab answer

Can you take Black Seed with Golimumab?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black seed might interfere with immunosuppressive therapy.

Full Black Seed + Golimumab answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Golimumab is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Golimumab, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Golimumab sits in 1 interaction category. Open any one to see what the group means:

Immunosuppressants 53 ingredients

Medications that damp down the immune system. Supplements that stimulate immunity can work against them.

53 of the supplement ingredients on this page reach Golimumab through this category.

About Golimumab

Golimumab injection is a TNF-blocking biologic used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis in adults and some pediatric patients.

Generic name: Golimumab  ·  Brand name: Simponi Aria.

See the full Golimumab Injection drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Golimumab

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Golimumab.

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Pharmacist Counseling Corner

Golimumab & Supplements: Common Questions

What supplements interact with Golimumab?
Our database currently documents 53 ingredients with a known Golimumab interaction (0 major, 52 moderate, 1 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 53. The highest-ranked right now: Active Hexose Correlated Compound (ahcc), Alfalfa, American Ginseng.
Which Golimumab supplement interactions are the most serious?
None of the Golimumab supplement interactions on file are currently rated major. The most significant are the 52 moderate-rated ones — combinations that may need monitoring, a dose adjustment, or separated timing. Still worth a quick look through the ranked list for anything you take daily. Jump to the ranked list.
Can I take vitamins or supplements while on Golimumab?
Plenty of supplements coexist fine with Golimumab; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Simponi Aria have the same supplement interactions as Golimumab?
Yes — Simponi Aria all contain Golimumab, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Golimumab and my other medications?
This page covers Golimumab against supplements and herbal ingredients. Checking Golimumab against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Golimumab Injection drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.