Medication interaction hub

What Supplements Interact with Isopropamide, Prochlorperazine?

Isopropamide, Prochlorperazine brand name: Combid. Every interaction below applies to the brands too.

96 Interactions 5 Major 67 Moderate 24 Minor
Curated & coded by · Clinical Pharmacist · Updated September 20, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Isopropamide, Prochlorperazine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Isopropamide, Prochlorperazine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Combid combines isopropamide, which quiets an overactive gut, with prochlorperazine, a phenothiazine used for nausea, and its interaction list warrants genuine care rather than a quick skim. Five of the 96 supplement ingredients on file carry a major rating. The biggest cluster is 30 herbs with anticholinergic activity, henbane among them, which stack dry mouth, blurred vision, constipation, and a racing heart on top of what isopropamide already causes. Another 17, led by activated charcoal, can keep the oral dose from being fully absorbed.

The prochlorperazine half brings its own concerns. Twenty ingredients may compound its tendency to make skin burn faster in sunlight, and herbs like Indian snakeroot can intensify its effects on the brain. With 67 moderate and 24 minor entries, most are managed by spacing doses well apart or plain watchfulness, but the five major ones deserve your attention before the rest.

— , Clinical Pharmacist · July 18, 2026

Major 5 Moderate 67 Minor 24 No known interaction 1,356

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Isopropamide, Prochlorperazine: Top Interactions at a Glance

The Isopropamide, Prochlorperazine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 96 interacting ingredients — plus 1,356 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Isopropamide, Prochlorperazine Combinations Today

The Isopropamide, Prochlorperazine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Vitex Agnus-castus + Isopropamide, Prochlorperazinei

Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.

Read the full interaction Moderate Likelihood Possible Jimson Weed + Isopropamide, Prochlorperazinei

Theoretically, jimson weed may increase anticholinergic effects and adverse effects.

Read the full interaction Minor Likelihood Unlikely Calabar Bean + Isopropamide, Prochlorperazinei

Theoretically, taking calabar bean might reduce the effects of anticholinergic drugs.

Read the full interaction Moderate Likelihood Possible Poria Mushroom + Isopropamide, Prochlorperazinei

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.

Read the full interaction Major Likelihood Probable Activated Charcoal + Isopropamide, Prochlorperazinei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Henbane + Isopropamide, Prochlorperazinei

Concomitant use of henbane can have additive anticholinergic effects and adverse effects with amantadine, antihistamines, atropine, belladonna alkaloids, hyoscy...

Read the full interaction
The complete list

Every Supplement Checked Against Isopropamide, Prochlorperazine

All 1,452 ingredients in our database, ranked by severity — 96 with a Isopropamide, Prochlorperazine interaction on file and 1,356 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Isopropamide, Prochlorperazine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Vitex Agnus-castus with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.

Full Vitex Agnus-castus + Isopropamide, Prochlorperazine answer

Can you take Jimson Weed with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, jimson weed may increase anticholinergic effects and adverse effects.

Full Jimson Weed + Isopropamide, Prochlorperazine answer

Can you take Calabar Bean with Isopropamide, Prochlorperazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking calabar bean might reduce the effects of anticholinergic drugs.

Full Calabar Bean + Isopropamide, Prochlorperazine answer

Can you take Poria Mushroom with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.

Full Poria Mushroom + Isopropamide, Prochlorperazine answer

Can you take Methylene Blue with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Methylene Blue + Isopropamide, Prochlorperazine answer

Can you take Nutmeg with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of nutmeg and anticholinergic drugs might decrease the effectiveness of either agent.

Full Nutmeg + Isopropamide, Prochlorperazine answer

Can you take Phosphatidylserine with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Full Phosphatidylserine + Isopropamide, Prochlorperazine answer

Can you take Purple Nut Sedge with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, purple nut sedge dose-dependently inhibits acetylcholinesterase (AChE).

Full Purple Nut Sedge + Isopropamide, Prochlorperazine answer

Can you take Rauwolscine with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.

Full Rauwolscine + Isopropamide, Prochlorperazine answer

Can you take Rue with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rue might increase the risk for phototoxicity when used with photosensitizing drugs.

Full Rue + Isopropamide, Prochlorperazine answer

Can you take Sage with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sage might decrease the clinical effects of anticholinergic drugs.

Full Sage + Isopropamide, Prochlorperazine answer

Can you take Slippery Elm with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Isopropamide, Prochlorperazine answer

Can you take St. John's Wort with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, St.

Full St. John's Wort + Isopropamide, Prochlorperazine answer

Can you take Syrian Rue with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Syrian rue might decrease the effects of anticholinergic drugs.

Full Syrian Rue + Isopropamide, Prochlorperazine answer

Can you take Teazle with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that teazle extract can inhibit acetylcholinesterase activity.

Full Teazle + Isopropamide, Prochlorperazine answer

Can you take Thuja with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Thuja products can contains significant amounts of thujone, a neurotoxin.

Full Thuja + Isopropamide, Prochlorperazine answer

Can you take Thyme with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of anticholinergic drugs and thyme essential oil might reduce the effects of anticholinergic drugs.

Full Thyme + Isopropamide, Prochlorperazine answer

Can you take Toothed Clubmoss with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopol...

Full Toothed Clubmoss + Isopropamide, Prochlorperazine answer

Can you take Tragacanth with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tragacanth might alter absorption of oral drugs.

Full Tragacanth + Isopropamide, Prochlorperazine answer

Can you take Wild Lettuce with Isopropamide, Prochlorperazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.

Full Wild Lettuce + Isopropamide, Prochlorperazine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Isopropamide, Prochlorperazine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Isopropamide, Prochlorperazine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Isopropamide, Prochlorperazine sits in 6 interaction categories. Open any one to see what the group means:

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Isopropamide, Prochlorperazine through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Isopropamide, Prochlorperazine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Isopropamide, Prochlorperazine through this category.

Phenothiazines 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Isopropamide, Prochlorperazine through this category.

Antipsychotic Drugs 8 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

8 of the supplement ingredients on this page reach Isopropamide, Prochlorperazine through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Isopropamide, Prochlorperazine through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Isopropamide, Prochlorperazine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Isopropamide, Prochlorperazine.

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Pharmacist Counseling Corner

Isopropamide, Prochlorperazine & Supplements: Common Questions

What supplements interact with Isopropamide, Prochlorperazine?
Our database currently documents 96 ingredients with a known Isopropamide, Prochlorperazine interaction (5 major, 67 moderate, 24 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 96. The highest-ranked right now: Activated Charcoal, Henbane, Indian Snakeroot.
Which Isopropamide, Prochlorperazine supplement interactions are the most serious?
The 5 major-rated combinations — led by Activated Charcoal, Henbane, Indian Snakeroot, Rauvolfia Vomitoria and Scopolia — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Isopropamide, Prochlorperazine?
Plenty of supplements coexist fine with Isopropamide, Prochlorperazine; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Combid have the same supplement interactions as Isopropamide, Prochlorperazine?
Yes — Combid all contain Isopropamide, Prochlorperazine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Isopropamide, Prochlorperazine and my other medications?
This page covers Isopropamide, Prochlorperazine against supplements and herbal ingredients. Checking Isopropamide, Prochlorperazine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 20, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.