Anabolic-Pump Ingredients & Drug Interactions
by USPlabs
What is this page for?
First and foremost: checking Anabolic-Pump against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Anabolic-Pump is a dietary supplement by USPlabs with 2 active ingredients. Its ingredients are commonly taken for digestive complaints and diarrhea, inflammation and joint discomfort, stress and weight management (in combination products).Based on those ingredients, 1,184 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phellodendron, Crape Myrtle. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Anabolic-Pump by USPlabs
Ask about any prescription or over-the-counter medication and we check it for interactions with Anabolic-Pump by USPlabs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Anabolic-Pump by USPlabs
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 2 active ingredients.
- “Proprietary Blend” is a proprietary blend — the label gives one combined amount (750 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 2 of the 2 matched ingredients can interact with medications — Banaba, Phellodendron.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
- For scale: 1,185 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Anabolic-Pump, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Anabolic-Pump by USPlabs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 750 mg | -- |
| Phellodendron | 0 NP | -- |
| Crape Myrtle | 0 NP | -- |
Other ingredients: Gelatin, Cellulose, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
DIETARY SUPPLEMENT
Precautions
KEEP OUT OF REACH OF CHILDREN.
Pregnant or nursing women should not use this product. Consult with your health care provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAO-B inhibitor or any other medication. Discontinue use and immediately consult your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.
Warning: This product is only intended to be consumed by healthy adults 18 years of age or older.
FDA Disclaimer Statement
†These statements have not been evaluated by the Food and Drug administration. This product is not intended to treat, diagnose, cure or prevent any disease.
General Statements
"The Genetic Equalizer"†
GAIN MUSCLE. LOSE FAT.†
TRIAL PACK
Ultra-Premium Supplements
Brand IP Statement(s)
††The proprietary blend, AnabolicPump(TM) is a registered trademark of USPlabs, LLC.
• Promote lean muscle tissue. † • Promote body fat reduction. † • Rapidly deliver nutrients directly into muscle tissue. † • May inhibit fat cells from multiplying – by blocking GLUT4 in fat cells. † • Enjoy HUGE, skin-busting pumps all day long, even on off days…Way better than anything ever produced, including NO-type products. † • Promote 24/7 post-workout “Window of Opportunity” – Potent round-the-clock nutrient-partitioning effect. † • None of the plant extracts or compounds in Anabolic-Pump(TM) are directly listed on the following lists†*: NCAA(TM) Banned-Drug Classes 2008-09 World Anti-doping Code Prohibited List 2009
At the time of manufacture, the ingredients in Anabolic-Pump(TM) do not appear on these banned substance lists. However, even though the active ingredients in Anabolic-Pump(TM) are natural, USPlabs cannot be responsible for the addition of its ingredients to any banned lists. Therefore, it is up to the athlete to check with his or her organization to confirm these ingredients are allowed.
Directions: As a dietary supplement, for the first 7 days take 1 cap twice daily, 15-20 minutes before carbohydrate containing meals. Each dose should be spaced 6-8 hours apart. After day 7, take 1 capsule 3 times daily 15-20 minutes before carbohydrate containing meals, preferably with breakfast, lunch and dinner.
Seals/Symbols
ENGINEERED EXTRACTS
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Anabolic-Pump by USPlabs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Anabolic-Pump by USPlabs
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
Other (inactive) ingredients: Gelatin, Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Anabolic-Pump by USPlabs Drug Interactions
Anabolic-Pump contains 2 ingredients, and 2 of them have known drug interactions. Altogether they interact with 1,184 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Anabolic-Pump?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Anabolic-Pump interact with 1,184 drugs. Click any drug to see the details.
2 of the 2 ingredients in Anabolic-Pump interact with drugs. Each result below shows which ingredient is responsible. Phellodendron Crape Myrtle
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Phellodendron + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Phellodendron + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Anabolic-Pump — through 2 ingredients. Tap an ingredient for the detail:
PhellodendronAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, phellodendron may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Phellodendron + Acarbose interactionCrape MyrtleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
Read the full Crape Myrtle + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Anabolic-Pump — through 2 ingredients. Tap an ingredient for the detail:
Crape MyrtleAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Read the full Crape Myrtle + Acebutolol interactionPhellodendronAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, phellodendron might have additive effects with antihypertensive drugs.
Read the full Phellodendron + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Phellodendron + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCns Depressants Moderate
Interaction Summary
Theoretically, phellodendron might increase the sedative effects of CNS depressants.
Read the full Phellodendron + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Phellodendron + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Phellodendron + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2D6.
Read the full Phellodendron + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase the sedative effects of CNS depressants.
Read the full Phellodendron + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2D6.
Read the full Phellodendron + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2D6.
Read the full Phellodendron + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2D6.
Read the full Phellodendron + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2D6.
Read the full Phellodendron + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates, Dextromethorphan (robitussin Dm, Others) +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2D6.
Read the full Phellodendron + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronDextromethorphan (robitussin Dm, Others), Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, phellodendron may increase serum levels of dextromethorphan.
Read the full Phellodendron + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Anabolic-Pump — through 1 ingredient. Tap an ingredient for the detail:
PhellodendronCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Read the full Phellodendron + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Anabolic-Pump with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Phellodendron
Anticoagulant/Antiplatelet Drugs
Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Phellodendron contains berberine. In vitro and in vivo research suggest that berberine can inhibit platelet aggregation. Theoretically, phellodendron might also inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, phellodendron may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Phellodendron contains berberine. Clinical research shows that berberine may lower blood glucose levels. Theoretically, phellodendron might also lower blood glucose levels.
Antihypertensive Drugs
Theoretically, phellodendron might have additive effects with antihypertensive drugs.
Phellodendron contains berberine. Animal research suggests that berberine can have hypotensive effects. Also, a clinical study suggests that taking berberine in combination with amlodipine can lower systolic and diastolic blood pressure when compared with amlodipine alone. Theoretically, phellodendron might also reduce blood pressure.
Cns Depressants
Theoretically, phellodendron might increase the sedative effects of CNS depressants.
Phellodendron contains berberine. Animal research suggests that berberine may have sedative effects. Theoretically, phellodendron might also have CNS depressants effects.
Cyclosporine (Neoral, Sandimmune)
Theoretically, phellodendron might increase blood levels of cyclosporine.
Phellodendron contains berberine. Preliminary clinical research shows that berberine can reduce metabolism of cyclosporine and increase serum levels, likely through inhibition of cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, phellodendron might also reduce the metabolism of cyclosporine.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2C9.
Phellodendron contains berberine. Preliminary clinical research shows that berberine can inhibit CYP2C9. Theoretically, phellodendron might also inhibit CYP2C9.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP2D6.
Phellodendron contains berberine. In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, phellodendron might also inhibit CYP2D6.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, phellodendron might increase serum levels of drugs metabolized by CYP3A4.
Phellodendron contains berberine. In vitro research and preliminary clinical research show that berberine moderately inhibits CYP3A4. Theoretically, phellodendron might also inhibit CYP3A4.
Dextromethorphan (Robitussin Dm, Others)
Theoretically, phellodendron may increase serum levels of dextromethorphan.
Phellodendron contains berberine. Preliminary clinical research shows that berberine can inhibit cytochrome P450 2D6 (CYP2D6) activity and reduce the metabolism of dextromethorphan. Theoretically, phellodendron may also inhibit the metabolism of dextromethorphan.
Losartan (Cozaar)
Theoretically, phellodendron might reduce the therapeutic effects of losartan by decreasing its conversion to its active form.
Phellodendron contains berberine. Preliminary clinical research suggests that berberine can inhibit cytochrome P450 2C9 (CYP2C9) activity and reduce metabolism of losartan. Theoretically, phellodendron might also inhibit the metabolism of losartan.
Metformin (Glucophage)
Theoretically, phellodendron might increase the therapeutic and adverse effects of metformin.
Phellodendron contains berberine. In vitro and animal studies show that berberine can increase the systemic exposure and half-life of metformin, potentially increasing metformin's effects and side effects. This interaction seems to be most apparent when berberine is administered 2 hours prior to metformin. Taking berberine and metformin at the same time does not appear to increase systemic exposure to metformin. It is unclear if phellodendron might have this same effect.
Midazolam (Versed)
Theoretically, phellodendron might reduce metabolism of midazolam, which might increase the risk of severe adverse effects.
Phellodendron contains berberine. Preliminary clinical research shows that berberine can inhibit cytochrome P450 3A4 (CYP3A4) activity and reduce metabolism of midazolam. Theoretically, phellodendron might also inhibit the metabolism of midazolam.
Pentobarbital (Nembutal)
Theoretically, phellodendron might increase the sedative effect of pentobarbital.
Phellodendron contains berberine. Animal research shows that berberine can prolong pentobarbital-induced sleeping time. Theoretically, phellodendron might increase the sedative effects of pentobarbital.
Tacrolimus (Prograf)
Theoretically, phellodendron might increase blood levels of tacrolimus.
Phellodendron contains berberine. In a 16-year-old patient with idiopathic nephrotic syndrome who was being treated with tacrolimus 6.5 mg twice daily, intake of berberine 200 mg three times daily increased the blood concentration of tacrolimus from 8 to 22 ng/mL. Following a reduction of the tacrolimus dose to 3 mg daily, blood levels of tacrolimus decreased to 12 ng/mL. It is unclear if phellodendron might have this same effect.
Crape Myrtle
Antidiabetes Drugs
Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
Human and animal research suggests that banaba can lower blood glucose levels.
Antihypertensive Drugs
Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Human and animal research suggests that banaba can lower blood pressure.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
In vitro research shows that banaba inhibits OATP, particularly OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the absorption of drugs and other compounds.
Brand information
Manufacturer and brand details for Anabolic-Pump, from the product label.
Anabolic-Pump by USPlabs: Common Questions
Does Anabolic-Pump by USPlabs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Anabolic-Pump’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Phellodendron
Interacts with 1,160 drugsPhellodendron is a traditional Chinese medicine bark (Huang Bai) that contains berberine and other plant compounds with antimicrobial and anti-inflammatory activity in lab studies. Human evi...
Read the full Phellodendron monograph → Herb & supplement monographBanaba
Interacts with 299 drugsBanaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may modestly lower glucose. The overall evide...
Read the full Banaba monograph →Sources & How We Checked
Anabolic-Pump's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 29 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phellodendron 22 references
- Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
- Janbaz KH, Gilani AH. Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. Fitoterapia 2000;71:25-33.. PubMed
- Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
- Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
- Zhang Y, Li X, Zou D, et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab 2008;93:2559-65. PubMed
- Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
- Chatterjee P, Franklin MR. Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components. Drug Metab Dispos 2003;31:1391-7. PubMed
- Shanbhag, S. M., Kulkarni, H. J., and Gaitonde, B. B. Pharmacological actions of berberine on the central nervous system. Jpn.J Pharmacol 1970;20(4):482-487. PubMed
- Wu, J. F. and Liu, T. P. [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. Yao Xue.Xue.Bao. 1995;30(2):98-102.
- Peng, W. H., Hsieh, M. T., and Wu, C. R. Effect of long-term administration of berberine on scopolamine-induced amnesia in rats. Jpn J Pharmacol 1997;74(3):261-266. DOI
- Sabir M and Bhide NK. Study of some pharmacological actions of berberine. Ind J Physiol & Pharmac 1971;15(3):111-132.
- Tripathi YB and Shukla SD. Berberis artistata inhibits PAF induced aggregation of rabbit platelets. Phytotherapy Research 1996;10:628-630.
- Yin, J., Xing, H., and Ye, J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism 2008;57(5):712-717. PubMed
- Zhang, H., Wei, J., Xue, R., Wu, J. D., Zhao, W., Wang, Z. Z., Wang, S. K., Zhou, Z. X., Song, D. Q., Wang, Y. M., Pan, H. N., Kong, W. J., and Jiang, J. D. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin re
- Guo, Y., Chen, Y., Tan, Z. R., Klaassen, C. D., and Zhou, H. H. Repeated administration of berberine inhibits cytochromes P450 in humans. Eur J Clin Pharmacol 2012;68(2):213-217. PubMed
- Wei, W., Zhao, H., Wang, A., Sui, M., Liang, K., Deng, H., Ma, Y., Zhang, Y., Zhang, H., and Guan, Y. A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndro
- Hermann, R. and von, Richter O. Clinical evidence of herbal drugs as perpetrators of pharmacokinetic drug interactions. Planta Med 2012;78(13):1458-1477. PubMed
- Chun YT, Yip TT, Lau KL, and et al. A biochemical study on the hypotensive effect of berberine in rats. Gen Pharmac 1979;10:177-182. PubMed
- Hou Q, Han W, Fu X. Pharmacokinetic interaction between tacrolimus and berberine in a child with idiopathic nephrotic syndrome. Eur J Clin Pharmacol 2013;69(10):1861-2. PubMed
- Lan J, Zhao Y, Dong F, et al. Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. J Ethnopharmacol. 2015;161:69-81. PubMed
- Kalman DS, Feldman S, Feldman R, et al. Effect of a proprietary magnolia and phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial. Nutr J 2008;7:11.
- Lyu Y, Zhang Y, Yang M, et al. Pharmacokinetic interactions between metformin and berberine in rats: Role of oral administration sequences and microbiota. Life Sci. 2019;235:116818. PubMed
Banaba 7 references
- Judy WV, Hari SP, Stogsdill WW, et al. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol 2003;87:115-7. PubMed
- Kakuda T, Sakane I, Takihara T, et al. Hypoglycemic effect of extracts from Lagerstroemia speciosa L. leaves in genetically diabetic KK-AY mice. Biosci Biotechnol Biochem 1996;60:204-8.
- Fukushima, M., Matsuyama, F., Ueda, N., Egawa, K., Takemoto, J., Kajimoto, Y., Yonaha, N., Miura, T., Kaneko, T., Nishi, Y., Mitsui, R., Fujita, Y., Yamada, Y., and Seino, Y. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res C PubMed
- Yamaguchi, Y., Yamada, K., Yoshikawa, N., Nakamura, K., Haginaka, J., and Kunitomo, M. Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci 11-25-2006;79(26):2474-2479. PubMed
- Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006;34:577-82. PubMed
- Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
- Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC