Versa-1 Ingredients & Drug Interactions
by USPlabs
What is this page for?
First and foremost: checking Versa-1 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Versa-1 is a dietary supplement by USPlabs with 2 active ingredients. Its ingredients are commonly taken for memory and thinking, brain health and aging, stroke recovery support.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are N-[2-hydroxy-2(4-methoxyphenyl) ethyl]-3-phenyl- 2-propenamide. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Versa-1 by USPlabs
Ask about any prescription or over-the-counter medication and we check it for interactions with Versa-1 by USPlabs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
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HelloPharmacist Scorecard of Versa-1 by USPlabs
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 2 active ingredients.
- “Proprietary Blend” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.
Only Minor-severity interactions are documented for these ingredients.
Why this rating?
- 1 of the 2 matched ingredients can interact with medications — Aegeline.
- The most serious interaction on file is rated Minor.
- For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Versa-1, straight from the product label.
| Brand | USPlabs |
|---|---|
| Barcode (UPC) | 094922426482 |
| Net contents | 30 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Oct 25, 2013 |
| DSLD ID | 27214 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Versa-1 by USPlabs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Citicoline | 0 NP | -- |
| Proprietary Blend | 400 mg | -- |
| N-[2-hydroxy-2(4-methoxyphenyl) ethyl]-3-phenyl- 2-propenamide | 0 NP | -- |
Other ingredients: Gelatin, Vegetable Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions for Use: Take one capsule daily with or without food. On workout days, take 30-60 minutes prior to exercise. May be taken with pre-workout supplement.
Precautions
Warning: This product is only intended to be consumed by healthy adults 18 years of age or older.
Consult with your Physician before using this product, especially if you are using any prescription or over the counter medication or if you have any pre-existing medical condition including but not limited to high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication. Do not use if you are pregnant, nursing, or may become pregnant.
Discontinue use 2 weeks prior to surgery. Discontinue use and consult with your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.
KEEP OUT OF REACH OF CHILDREN.
This product is produced in a facility that processes milk and soy ingredients.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, diagnose, cure or prevent any disease.
General Statements
R&D-P12-158
30 Day Cycle
NEW Patent Pending Anabolic
VERSA-1; the first of its kind. Take your training to new levels and feel the unique power of this NEW patent pending breakthrough.
Questions, comments or concerns can be directed to our forums at www.usplabsdirect.com or by phone at: 1-800-890-3067 (9-5 EST Mon-Fri)
Seals/Symbols
USPlabs Ultra-Premium Supplements(R)
Brand IP Statement(s)
MUSCLE / MIND BREAKTHROUGH(TM)
FDA Statement of Identity
DIETARY SUPPLEMENT
General
L-648-01
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Versa-1 by USPlabs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Versa-1 by USPlabs
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
Other (inactive) ingredients: Gelatin, Vegetable Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Versa-1 by USPlabs Drug Interactions
Versa-1 contains 2 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 643 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Versa-1?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Versa-1 interact with 643 drugs. Click any drug to see the details.
1 of the 2 ingredients in Versa-1 interact with drugs. Each result below shows which ingredient is responsible. N-[2-hydroxy-2(4-methoxyphenyl) ethyl]-3-phenyl- 2-propenamide
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acalabrutinib interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Versa-1 — through 1 ingredient. Tap an ingredient for the detail:
N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamideCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro.
Read the full N-[2-hydroxy-2(4-methoxyphenyl) Ethyl]-3-phenyl- 2-propenamide + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Versa-1 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
N-[2-hydroxy-2(4-methoxyphenyl) ethyl]-3-phenyl- 2-propenamide
Cytochrome P450 3A4 (Cyp3A4) Substrates
Aegeline inhibits cytochrome P450 3A4 (CYP3A4) activity in vitro. So far, this interaction has not been reported in humans. Theoretically, aegeline may increase levels of drugs metabolized by CYP3A4. Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and numerous others. Use aegeline cautiously or avoid in patients taking these drugs.
Brand information
Manufacturer and brand details for Versa-1, from the product label.
Versa-1 by USPlabs: Common Questions
Does Versa-1 by USPlabs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Versa-1’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Citicoline
Citicoline is a naturally occurring compound involved in making brain cell membranes and the messenger chemical acetylcholine. It is popularly taken for memory, focus, and brain aging, and s...
Read the full Citicoline monograph → Herb & supplement monographAegeline
Interacts with 643 drugsAegeline is a compound originally identified in the bael tree (Aegle marmelos) that gained attention because it was added to some weight-loss and workout supplements. It is best known for be...
Read the full Aegeline monograph →Sources & How We Checked
Versa-1's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 19 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Citicoline 11 references
- Spiers PA, Myers D, Hochanadel GS, et al. Citicoline improves verbal memory in aging. Arch Neurol 1996;53:441-8. PubMed
- Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev 2005;(2):CD000269. PubMed
- Conant R, Schauss AG. Therapeutic applications of citicoline for stroke and cognitive function in the elderly: A review of the literature. Altern Med Rev 2004;9:17-31.
- Warach, S., Pettigrew, L. C., Dashe, J. F., Pullicino, P., Lefkowitz, D. M., Sabounjian, L., Harnett, K., Schwiderski, U., and Gammans, R. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 0 DOI
- Lukas, S. E., Kouri, E. M., Rhee, C., Madrid, A., and Renshaw, P. F. Effects of short-term citicoline treatment on acute cocaine intoxication and cardiovascular effects. Psychopharmacology.(Berl.) 2001;157(2):163-167. PubMed
- Dinsdale, J. R., Griffiths, G. K., Castello, J., Maddock, J., Ortiz, J. A., and Aylward, M. CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers. Arzneimittelforschung. 1983;33(7A):1061-1065.
- Clark BC, Georgekutty J, Berul CI. Myocardial ischemia secondary to synthetic cannabinoid (K2) use in pediatric patients. J Pediatr 2015;167(3):757-61.e1. PubMed
- Ghajar A, Gholamian F, Tabatabei-Motlagh M, et al. Citicoline (CDP-choline) add-on therapy to risperidone for treatment of negative symptoms in patients with stable schizophrenia: a double-blind, randomized placebo-controlled trial. Hum Psychopharmacol. 2
- Castagna A, Manzo C, Fabbo A, Lacava R, Ruberto C, Ruotolo G. The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease. Clin Drug Investig. 2021 Feb;41(2):177-182. PubMed
- Jeong H, Yoon S, Sung YH, et al. Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study. J Psychiatr Res 2021;143:215-221. PubMed
- Nakazaki E, Mah E, Sanoshy K, Citrolo D, Watanabe F. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr 2021;151(8):2153-2160. PubMed
Aegeline 8 references
- Johnston DI, Chang A, Viray M, et al. Hepatotoxicity associated with the dietary supplement OxyELITE Pro - Hawaii, 2013. Drug Test Anal. 2016;8(3-4):319-27. PubMed
- Manda VK, Avula B, Chittiboyina AG, Khan IA, Walker LA, Khan SI. Inhibition of CYP3A4 and CYP1A2 by Aegle marmelos and its constituents. Xenobiotica. 2016;46(2):117-25.
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. OxyELITE Pro. [Updated 2016 May 20]. Available from: https://www.ncbi.nlm.nih.gov/
- Klontz KC, DeBeck HJ, LeBlanc P, et al. The Role of Adverse Event Reporting in the FDA Response to a Multistate Outbreak of Liver Disease Associated with a Dietary Supplement. Public Health Rep. 2015;130(5):526-532. PubMed
- Chatham-Stephens K, Taylor E, Chang A, et al. Hepatotoxicity associated with weight loss or sports dietary supplements, including OxyELITE Pro - United States, 2013. Drug Test Anal. 2017;9(1):68-74. PubMed
- Heidemann LA, Navarro VJ, Ahmad J, et al. Severe acute hepatocellular injury attributed to OxyELITE Pro: A case series. Dig Dis Sci. 2016;61(9):2741-8. PubMed
- Roytman MM, Pörzgen P, Lee CL, et al. Outbreak of severe hepatitis linked to weight-loss supplement OxyELITE Pro. Am J Gastroenterol. 2014;109(8):1296-8. PubMed
- Skinner CM, Miousse IR, Ewing LE, et al. Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments. Food Chem Toxicol. 201 PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC