Brahmihills Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Brahmihills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Brahmihills is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, anxiety and stress, adhd symptoms.Based on those ingredients, 930 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Brahmi leaves extract & Brahmi leaves powder Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Brahmihills by Herbal Hills
Ask about any prescription or over-the-counter medication and we check it for interactions with Brahmihills by Herbal Hills — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Brahmihills by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Brahmihills is a single-ingredient product: bacopa extract and powder blend from brahmi leaves. Bacopa is an herb traditionally used in Ayurvedic medicine and is often promoted for brain and cognitive support.
The capsules also contain magnesium stearate, silica, and gelatin as inactive ingredients.
Does it work?
Not established
The evidence for bacopa in this product isn't established in the data we hold. Our records show insufficient reliable evidence to rate bacopa for Alzheimer disease, sexual dysfunction, ADHD, back pain, cognitive function, and cognitive impairment.
If you're considering this product for one of those uses, talk with your pharmacist about what the current research actually shows.
How safe is it?
Well-documented data
Bacopa is generally well tolerated, though quality and long-term safety data are limited. The most common side effects are gastrointestinal — abdominal cramps, diarrhea, dry mouth, nausea, and headache.
Some people have also reported drowsiness, insomnia, or vivid dreams. Rates of gastrointestinal side effects in studies ranged from 12% to 30%.
There isn't enough safety information to use bacopa during pregnancy or while breastfeeding — talk with your doctor or pharmacist about your personal situation.
Meds to double-check
Moderate interaction found
Check with your pharmacist before using this if you take cevimeline (Evoxac) or any medications broken down by your liver's CYP1A2, CYP2C9, CYP2C19, or CYP3A4 enzymes — these include many common drugs. Also check if you take cholinergic drugs, anticholinergic drugs, or thyroid hormone.
The search tool on this page will help you verify your specific medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Bacopa in this product has potential interactions with a large number of medications, especially those your liver breaks down, as well as cholinergic and anticholinergic drugs. If you take any prescription medications, check them with the search tool before starting.
The evidence for bacopa's effectiveness for cognitive or other conditions isn't established in our data. Talk with your pharmacist before adding this to your routine, especially if you're pregnant, breastfeeding, or on other medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Brahmihills, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8906008260915 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2012 |
| DSLD ID | 15530 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Brahmihills by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Brahmi leaves extract & Brahmi leaves powder Blend | 300 mg | -- |
Other ingredients: Magnesium Stearate, Silica, Gelatin Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Direction for use : As a dietary supplement take 1 capsule twice daily, preferably after meals or as recommended by a Healthcare Practitioner. For better results it should be taken with warm water
Precautions
Caution : Pregnant or lactating women are advised to consume herbal products under the advice of the Healthcare Practitioner.
Keep out of reach of children.
Do not use if inner seal is broken or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
MULTIEFFECTIVE HERB
Batch No. : Exp. Date: Neutral Code # MH/PD/AYU/002/10
Brain Tonic
Pure – Natural – Effective Brahmi is a very popular brain tonic herb. It helps boost longevity, improve mental functions & learning ability. Brahmi has active ingredient Bacosides which helps in improving learning ability, enhancing grasping power, concentration & alertness.
Contents based on standard Raw Material as per Ayurvedic Text
FDA Statement of Identity
HERBAL SUPPLEMENT
Dietary Supplement
Seals/Symbols
HERBALHILLS
GMP Good Manufacturing Practice
ISO 22000:2005 CERTIFIED COMPANY
EXTRACT STANDARDIZED EXTRACT
Storage
Store in a cool dry place away from direct sunlight.
Formula
25% Total Bacosides, 27% Saponins
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Brahmihills by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Brahmihills by Herbal Hills
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Brahmi leaves extract & Brahmi leaves powder Blend
Interacts with930 drugs
Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for s...
Brahmi leaves extract & Brahmi leaves powder Blend monograph & interactionsOther (inactive) ingredients: Magnesium Stearate, Silica, Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.
Brahmihills by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Brahmihills by Herbal Hills contains bacopa, which interacts with several medication types.
The most serious documented interaction involves cevimeline (Evoxac), a medication for dry mouth in Sjögren syndrome — bacopa may boost its effects and side effects, and there's a case report of a person experiencing increased sweating, weakness, nausea, and rapid heartbeat shortly after taking bacopa with this drug.
Read the full breakdown — every affected drug type, severity by severity
Bacopa also affects how your liver breaks down a wide range of medications. It may inhibit four major liver enzymes (CYP1A2, CYP2C9, CYP2C19, and CYP3A4), meaning it could raise levels of drugs that depend on these enzymes, making them stronger or more likely to cause side effects.
Additionally, bacopa interacts with cholinergic drugs (medications that boost a nerve chemical called acetylcholine) — it may add to their effects — and anticholinergic drugs (which block acetylcholine), where it might reduce their effectiveness. Finally, bacopa may have additive effects when combined with thyroid hormone medication.
Altogether, these interactions span 919 individual medications. Because many common drugs depend on those liver enzymes, you'll want to check your exact medications with the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Brahmihills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Brahmihills interact with 930 drugs. Click any drug to see the details.
1 of the 1 ingredient in Brahmihills interact with drugs. Each result below shows which ingredient is responsible. Brahmi leaves extract & Brahmi leaves powder Blend
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acalabrutinib interactionAcepromazineAtravet
How Acepromazine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendAnticholinergic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Brahmihills — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Leaves Extract & Brahmi Leaves Powder BlendCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Leaves Extract & Brahmi Leaves Powder Blend + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Brahmihills with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Brahmi leaves extract & Brahmi leaves powder Blend
Anticholinergic Drugs
Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.
Cevimeline (Evoxac)
Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.
Cholinergic Drugs
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Thyroid Hormone
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.
Brand information
Manufacturer and brand details for Brahmihills, from the product label.
Herbal Hills
See all Herbal Hills products- Name
- Isha Agro Developers Pvt. Ltd. (An ISO 22000:2005 Certified Company)
- Street Address
- 55-A/B, Lonavala Indl. Co-op. Est. Ltd.
- City
- Nangargaon
- State
- Lonavala
- Phone Number
- 0091 22 2868 6868
- Web Address
- www.herbalhills.in
Brahmihills by Herbal Hills: Common Questions
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The Full Monographs Behind Brahmihills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Brahmihills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bacopa 12 references
- Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology 2001;156:481-4..
- Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496-503..
- Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
- Kar, A., Panda, S., and Bharti, S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol. 2002;81(2):281-285. PubMed
- Mukherjee, G. D. and Dey, C. D. Clinical trial on Brahmi. I. J.Exp.Med.Sci. 1966;10(1):5-11.
- Kar A, Pandit S, Mukherjee K, Bahadur S, Mukherjee PK. Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study. J Sci Food Agric 2017;97(1):333-40. doi: 10.1002/jsfa.7739. PubMed
- Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014;151(1):528-35. PubMed
- Ramasamy S, Kiew LV, Chung LY. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents. Molecules 2014;19(2):2588-601. PubMed
- Prabhakar S, Vishnu VY, Modi M, et al. Efficacy of Bacopa monnieri (Brahmi) and donepezil in Alzheimer's disease and mild cognitive impairment: a randomized double-blind parallel phase 2b study. Ann Indian Acad Neurol 2020;23(6):767-73. PubMed
- Acquarulo B, Tandon P, Macica CM. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report. J Med Case Rep 2022;16(1):253. PubMed
- Keegan AP, Stough C, Paris D, et al. Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderl
- Yaworski AM, Blyumin M, Chang T, Mammen AL, Greene M. Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa. Muscle Nerve 2023;67(2):E1-E3.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC