Censor Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Censor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Censor is a dietary supplement by NDS Nutrition Products with 5 active ingredients. Its ingredients are commonly taken for heart and cholesterol support, skin moisturizing, menstrual cramps.Based on those ingredients, 574 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fish Oil, Flaxseed oil, Evening primrose oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Censor by NDS Nutrition Products
Ask about any prescription or over-the-counter medication and we check it for interactions with Censor by NDS Nutrition Products — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Censor by NDS Nutrition Products
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Censor contains six ingredients. The active components are a blend of polyunsaturated fats and omega oils—safflower oil, fish oil, flaxseed oil, evening primrose oil, and borage oil.
These are all fatty acid sources meant to deliver omega-3, omega-6, and other lipid compounds. The product also contains inactive ingredients: gelatin (the capsule), glycerin, and vitamin E (d-alpha-tocopherol).
Does it work?
Moderate evidence
The evidence for these individual ingredients is mixed and often limited. Fish oil shows effectiveness for high triglycerides, and possibly helps with cachexia (severe weight loss), heart failure, and fatty liver disease.
Safflower, flaxseed, evening primrose, and borage oil all show insufficient or possibly ineffective evidence for their marketed uses—including weight management, cholesterol, rheumatoid arthritis, and skin conditions. The data we hold doesn't establish that this combination works for any specific condition.
How safe is it?
Well-documented data
Fish oil is generally well tolerated at typical supplement doses, though it can cause abdominal pain, bad breath, fishy aftertaste, heartburn, loose stools, nausea, and rash in some people. At doses of 3 grams or more daily, it may thin the blood and increase bleeding risk.
Safflower oil in food amounts is well tolerated, but concentrated supplements have less safety data; there are rare case reports of liver failure linked to high-dose safflower use. Flaxseed oil is generally well tolerated but may cause loose stools, diarrhea, dry mouth, or upset stomach at high doses.
Evening primrose and borage oils are generally well tolerated short-term, though they can cause abdominal upset, diarrhea, bloating, and belching. Borage oil raises a concern: some borage plant parts contain liver-toxic alkaloids, though borage seed oil certified as alkaloid-free is considered safer.
For pregnancy and breastfeeding, fish oil is often used but requires doctor oversight; safflower is possibly unsafe in pregnancy and should be avoided in medicinal amounts; flaxseed is possibly safe but lacks full data; evening primrose is possibly safe; borage is likely unsafe in pregnancy and lactation.
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take blood thinners or anticoagulants (especially warfarin), antihypertensive drugs (blood pressure medications), immunosuppressants like tacrolimus or cyclosporine, contraceptive drugs, antipsychotics (phenothiazines), lithium, orlistat, ezetimibe, lopinavir/ritonavir, or any drug metabolized by the liver. These represent the most serious interaction categories documented across this product's ingredients.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is a multi-ingredient omega and fatty acid blend. If you take any blood thinners, antihypertensives, immunosuppressants, antipsychotics, or other prescription medications, run this product through the interaction checker below before you start—the interaction list is substantial.
Talk to your pharmacist, especially if you're pregnant, breastfeeding, or have liver concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Censor, straight from the product label.
| Brand | NDS Nutrition Products |
|---|---|
| Barcode (UPC) | 811020907015 |
| Net contents | 180 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2014 |
| DSLD ID | 31320 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Censor by NDS Nutrition Products, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 {Calories} | -- |
| Calories from Fat | 20 {Calories} | -- |
| Polyunsaturated Fat | 1 Gram(s) | -- |
| Total Fat | 2 Gram(s) | 4% |
| CLA/Omega 3-6-9 Blend | 2 Gram(s) | -- |
| Safflower oil | 0 NP | -- |
| Fish Oil | 0 NP | -- |
| Flaxseed oil | 0 NP | -- |
| Evening primrose oil | 0 NP | -- |
| Borage oil | 0 NP | -- |
Other ingredients: Gelatin, Glycerin, D-Alpha-Tocopherol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Contains fish (anchovy, sardine, mackerel) ingredients.
Featuring Tonalin(R)
Supports Healthy Dieting with CLA Includes an Omega 3-6-9 Blend
Precautions
Contains fish (anchovy, sardine, mackerel) ingredients.
WARNING: Do not exceed recommended dose.
Not intended for use by persons under 18 years of age.
Do not use if pregnant or lactating.
If you are under the care of a physician, please consult your physician before using this product. Do not use if tamper resistant seal is broken.
KEEP OUT OF REACH OF CHILDREN.
Brand IP Statement(s)
Tonalin(R) CLA is an exclusively licensed trademark of Cognis under U.S. Patents #5,554,646, 5,428,072, 5,430,066 and 6,015,833
FDA Statement of Identity
Dietary Supplement
General Statements
BODY TONER
SUPPORT FAT LOSS
Economy Size
Suggested/Recommended/Usage/Directions
SUGGESTED USE: As a dietary supplement, take 2 softgels up to three times daily with meals. To be used as part of a healthy lifestyle with regular physical activity and a proper diet.
Storage
STORE IN A COOL DRY PLACE.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
NDS(TM)
General
907015-1
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Censor by NDS Nutrition Products label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Censor by NDS Nutrition Products
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
CLA/Omega 3-6-9 Blend
Other (inactive) ingredients: Gelatin, Glycerin, D-Alpha-Tocopherol. These complete the product’s ingredient list but are not active constituents.
Censor by NDS Nutrition Products Drug Interactions
HelloPharmacist Interaction Report
Censor by NDS Nutrition Products contains six ingredients, five of which we could check for interactions with medications.
Altogether, these interactions span 575 individual medications. The most serious concern is safflower oil with blood thinners (anticoagulants) and the anticoagulant warfarin specifically—both are Moderate severity—because high doses of safflower oil can increase bleeding risk, and one case report documented elevated INR and bleeding in a patient on warfarin after taking safflower extract.
Read the full breakdown — every affected drug type, severity by severity
Fish oil also carries Moderate-severity interactions with several drug types: antihypertensive drugs (blood pressure medication), contraceptive drugs, immunosuppressants (tacrolimus, cyclosporine, sirolimus), and orlistat for weight loss. It has Minor-severity interactions with anticoagulants and warfarin.
Flaxseed oil has Moderate interactions with antihypertensive drugs, anticoagulants and antiplatelet drugs, and ezetimibe (a cholesterol drug). Evening primrose oil interacts at Moderate severity with anticoagulants and antiplatelet drugs, lithium, phenothiazines (antipsychotic drugs), and lopinavir/ritonavir (HIV medication), plus Minor interactions with certain liver-processed drugs.
Borage oil carries Moderate-severity interactions with anticoagulants and antiplatelet drugs, phenothiazines, and CYP3A4-inducing drugs.
We could not check polyunsaturated fat for interactions. Check your exact medications with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Censor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Censor interact with 574 drugs. Click any drug to see the details.
5 of the 5 ingredients in Censor interact with drugs. Each result below shows which ingredient is responsible. Fish Oil Flaxseed oil Evening primrose oil Borage oil Safflower oil
AbciximabReoPro
How Abciximab interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Evening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Abciximab interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Abciximab interactionSafflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Abciximab interactionBorage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Abciximab interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Abrocitinib interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Abrocitinib interactionEvening Primrose OilCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Evening Primrose Oil + Abrocitinib interactionSafflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Abrocitinib interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Censor — through 1 ingredient. Tap an ingredient for the detail:
Safflower OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Read the full Safflower Oil + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Acebutolol interactionFlaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acenocoumarol interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Acenocoumarol interactionSafflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Acenocoumarol interactionEvening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Acenocoumarol interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Evening Primrose OilPhenothiazines Moderate
Interaction Summary
Theoretically, taking evening primrose oil with phenothiazines might increase the risk of convulsions.
Read the full Evening Primrose Oil + Acepromazine interactionBorage OilPhenothiazines Moderate
Interaction Summary
Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Read the full Borage Oil + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetaminophen, Aspirin interactionEvening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Acetaminophen, Aspirin interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Acetaminophen, Aspirin interactionSafflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Acetaminophen, Aspirin interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Safflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Acetaminophen, Aspirin, Caffeine interactionBorage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetaminophen, Aspirin, Caffeine interactionEvening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Acetaminophen, Aspirin, Caffeine interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Acetaminophen, Aspirin, Caffeine interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Safflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Acetaminophen, Ibuprofen interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Acetaminophen, Ibuprofen interactionBorage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetaminophen, Ibuprofen interactionEvening Primrose OilCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Evening Primrose Oil + Acetaminophen, Ibuprofen interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Acetazolamide interactionFlaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Censor — through 1 ingredient. Tap an ingredient for the detail:
Safflower OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Read the full Safflower Oil + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Safflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Acetylsalicylic Acid interactionBorage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Acetylsalicylic Acid interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Acetylsalicylic Acid interactionEvening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Acetylsalicylic Acid interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Censor — through 1 ingredient. Tap an ingredient for the detail:
Safflower OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Read the full Safflower Oil + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Aliskiren interactionFish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Censor — through 1 ingredient. Tap an ingredient for the detail:
Safflower OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Read the full Safflower Oil + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Censor — through 1 ingredient. Tap an ingredient for the detail:
Safflower OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Read the full Safflower Oil + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Censor — through 1 ingredient. Tap an ingredient for the detail:
Safflower OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Read the full Safflower Oil + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Safflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Alteplase, Tpa interactionEvening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Alteplase, Tpa interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Alteplase, Tpa interactionBorage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Alteplase, Tpa interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Borage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionEvening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionSafflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionFlaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Censor — through 5 ingredients. Tap an ingredient for the detail:
Flaxseed OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionEvening Primrose OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Evening Primrose Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionBorage OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionSafflower OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Safflower Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionFish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fish Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Ambrisentan interactionFlaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Amiloride interactionFish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Amiloride, Hydrochlorothiazide interactionFlaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Amiloride, Hydrochlorothiazide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Censor — through 1 ingredient. Tap an ingredient for the detail:
Borage OilCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil + Aminoglutethimide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Evening Primrose OilCytochrome P450 2c9 (cyp2c9) Substrates, Phenothiazines Moderate
Interaction Summary
Theoretically, evening primrose may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Evening Primrose Oil + Amitriptyline, Perphenazine interactionBorage OilPhenothiazines Moderate
Interaction Summary
Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Read the full Borage Oil + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Amlodipine interactionFlaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Amlodipine Benzoate interactionFish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Amlodipine Besilate interactionFlaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Flaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Amlodipine Besylate interactionFish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Censor — through 2 ingredients. Tap an ingredient for the detail:
Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Fish Oil + Amlodipine Besylate, Benazepril interactionFlaxseed OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Flaxseed Oil + Amlodipine Besylate, Benazepril interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Censor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Fish Oil
Antihypertensive Drugs
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Clinical evidence indicates that fish oils can modestly lower blood pressure and might have additive effects in patients treated with antihypertensives.
Contraceptive Drugs
Theoretically, taking fish oil with contraceptive drugs might decrease the triglyceride-lowering effects of fish oil.
There is some evidence that contraceptive drugs might interfere with the triglyceride lowering effects of fish oils.
Cyclosporine (Neoral, Sandimmune)
Taking fish oil with cyclosporine might increase levels and adverse effects of cyclosporine.
In kidney transplant recipients on a general immunosuppressive regimen, taking omega-3 fatty acids daily seems to increase peak blood levels of cyclosporine when compared with placebo. This increase was as much as 20% after one month. However, the area under the curve was not significantly affected.
Orlistat (Xenical, Alli)
Theoretically, taking fish oil with orlistat might decrease the absorption of fish oil fatty acids.
Orlistat binds lipase in the gastrointestinal tract and reduces fat absorption. Theoretically, taking fish oil with orlistat might decrease absorption of fish oil fatty acids. To avoid this potential interaction, recommend separating administration of orlistat and fish oil by at least 2 hours.
Sirolimus (Rapamune)
Taking fish oil with sirolimus might increase levels and adverse effects of sirolimus.
Pharmacokinetic research shows that omega-3 fatty acids increase exposure to sirolimus in kidney transplant patients on a calcineurin inhibitor-free immunosuppressive regimen. A 25% dose reduction in sirolimus was required to keep patients within the expected trough-concentration window. Researchers hypothesize that this may be due to inhibition of cytochrome P450 3A4 (CYP3A4) by fish oil, although this has not been confirmed in clinical research.
Tacrolimus (Prograf)
Taking fish oil with tacrolimus might increase levels and adverse effects of tacrolimus.
In a small group of patients, taking fish oil 2.6 grams (Omacor) daily for 4 weeks increased the 8-hour area under the curve of tacrolimus by 25% when compared with baseline. Peak levels were increased by approximately 22%. Researchers hypothesize that this may be due either to an increase in bioavailability or to inhibition of cytochrome P450 3A4 (CYP3A4) by fish oil, although this has not been confirmed in clinical research.
Anticoagulant/Antiplatelet Drugs
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, evidence is conflicting.
While fish oil may not be a potent inhibitor of platelet function, high doses of fish oil might have antiplatelet effects. Theoretically, concomitant use of fish oil with anticoagulant or antiplatelet drugs may increase the risk of bleeding. However, the most rigorous research shows that short-term doses of fish oil 10 grams daily or long-term doses of 1.5 grams daily for up to 52 weeks does not increase the risk of bleeding or affect coagulation parameters in chronically ill and vulnerable patients. Other controlled research shows that fish oil does not affect platelet function or increase the risk of bleeding. Some research even suggests that perioperative fish oil use decreases bleeding risk. Some research suggests fish oil does not have additive antiplatelet effects when combined with aspirin, but other clinical evidence suggests that adding fish oil to low-dose aspirin treatment increases antiplatelet effects in patients who are aspirin-resistant. Also, some clinical research seems to show that fish oil has additive antiplatelet effects when used with aspirin and clopidogrel compared to aspirin and clopidogrel alone.
Platinum Agents
Theoretically, taking fish oil with platinum agents can cause resistance to platinum agents, potentially decreasing their effectiveness.
Platinum-induced fatty acids (PIFAs) are fatty acids secreted from human and mouse stem cells when exposed to platinum-based chemotherapy. Animal research suggests that PIFAs cause resistance to chemotherapy by stimulating lysophospholipid production in the spleen, which interferes with the DNA damage caused by certain chemotherapy drugs. One PIFA, known as 16:4(n-3), has been found in both raw fish and some commercially available fish oil products. Mackerel and herring have high PIFA concentrations, while salmon and tuna have low PIFA concentrations. Levels of PIFA in commercial fish oil products ranged from 0.2- 5.7 microMol. Animal research shows that PIFA-containing fish oil products cause resistance to cisplatin, fluorouracil, irinotecan, and oxaliplatin. It is unclear if all commercially available fish oil products contain PIFAs. Additionally, it is argued that levels of PIFA found in some fish oil products are too low to be of clinical concern. Furthermore, a lack of chemotherapy resistance in countries with high fish intake, such as Greenland, Japan, and Norway, suggest that this interaction may not be clinically significant.
Warfarin (Coumadin)
Fish oil may have antiplatelet effects and might increase the risk of bleeding if used with warfarin.
Fish oil has antiplatelet effects at high doses. Case reports show elevated INR in patients taking warfarin and fish oil 1-2 grams daily. However, some clinical research shows that taking fish oil 3-6 grams daily does not significantly increase INR in patients taking warfarin.
Flaxseed oil
Anticoagulant/Antiplatelet Drugs
Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Small clinical studies show that consuming flaxseed oil might decrease platelet aggregation and increase bleeding time.
Antihypertensive Drugs
Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Some clinical evidence suggests that long-term consumption of flaxseed oil can modestly lower systolic and diastolic blood pressure, while other clinical research shows no effect.
Ezetimibe (Zetia)
Concomitant use of flaxseed oil and ezetimibe reduces the absorption of alpha-linolenic acid from flaxseed oil.
In one clinical study, concomitant consumption of ezetimibe 10 mg daily with flaxseed oil 2 grams providing 1 gram of alpha-linolenic acid daily blocked the absorption of alpha-linolenic acid, resulting in an overall reduction in alpha-linolenic plasma levels from baseline.
Evening primrose oil
Anticoagulant/Antiplatelet Drugs
Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Evening primrose oil contains gamma linolenic acid (GLA). There is preliminary clinical evidence that GLA can reduce platelet aggregation and prolong bleeding time.
Lithium
Theoretically, concomitant use of lithium with evening primrose oil might decrease lithium levels and effects.
In a case report, a patient on a stable dose of lithium for 10 years experienced a reduction in lithium levels after taking evening primrose oil 500 mg daily. Baseline levels were 0.69 mmol/L, which decreased to 0.37 mmol/L after 2 months and 0.23 mmol/L after 3 months of use. Lithium levels increased within 6 weeks of discontinuing evening primrose oil, to 0.73 mmol/L; no clinical effects were noted.
Lopinavir/Ritonavir (Kaletra)
Theoretically, evening primrose oil might increase the levels and effects of lopinavir.
In a case report, an HIV patient who took evening primrose oil (Efamol) along with lopinavir/ritonavir experienced an increase in serum levels of lopinavir to 15.2 mg/L. Six weeks after discontinuing evening primrose oil, levels of lopinavir returned to the normal range of 5-10 mg/L. When re-challenged with evening primrose oil for a week, the patient's lopinavir levels increased from 6.69 to 8.11 mg/L. It is suspected that evening primrose oil increases levels of lopinavir by inhibiting cytochrome P450 3A4 (CYP3A4), which metabolizes lopinavir. However, this effect has not been reported in other research.
Phenothiazines
Theoretically, taking evening primrose oil with phenothiazines might increase the risk of convulsions.
Evening primrose oil contains gamma-linolenic acid (GLA). There is some concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with GLA, although none experienced an actual seizure. In another report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose oil 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose oil had any additive epileptogenic effects with the phenothiazines; there is no evidence that taking evening primrose oil alone causes seizures.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, evening primrose may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that linoleic acid, a constituent of evening primrose oil, inhibits CYP2C9.
Borage oil
Anticoagulant/Antiplatelet Drugs
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.
Cytochrome P450 3A4 (Cyp3A4) Inducers
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.
Phenothiazines
Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.
Safflower oil
Anticoagulant/Antiplatelet Drugs
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Small clinical studies show that taking safflower oil, approximately 55 grams daily for 2-3 weeks, decreases platelet aggregation. However, taking lower doses of safflower oil, such as 5 grams daily for 4 weeks, does not seem to affect platelet function. In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.
Antidiabetes Drugs
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Some clinical research shows that taking safflower oil 10 grams daily for 3 weeks can increase fasting blood glucose in patients with type 2 diabetes. However, clinical research in patients with metabolic syndrome with or without impaired glucose tolerance shows that taking safflower oil 8 grams daily for 12 weeks reduces fasting glucose levels by around 8 mg/dL. Some clinical research also shows that taking safflower oil 8 grams daily for 16 weeks does not affect fasting glucose levels in patients with type 2 diabetes.
Warfarin
Theoretically, safflower oil might increase the risk of bleeding when taken with warfarin.
In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.
Brand information
Manufacturer and brand details for Censor, from the product label.
NDS Nutrition Products
See all NDS Nutrition Products products- Name
- NDS Nutrition Products, Inc.
- Street Address
- 11011 Q St., Ste. 106A
- City
- Omaha
- State
- NE
- ZipCode
- 68137
- Web Address
- www.ndsnutrition.com
Censor by NDS Nutrition Products: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Censor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Safflower
Interacts with 208 drugsSafflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source of unsaturated fats, but strong proof tha...
Read the full Safflower monograph → Herb & supplement monographFish Oil
Interacts with 327 drugsFish oil provides omega-3 fatty acids (EPA and DHA) that are best known for lowering high triglyceride levels. The evidence for other heart and health benefits is mixed, and it is generally...
Read the full Fish Oil monograph → Herb & supplement monographFlaxseed Oil
Interacts with 293 drugsFlaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help support heart health and provide healthy...
Read the full Flaxseed Oil monograph → Herb & supplement monographEvening Primrose
Interacts with 233 drugsEvening primrose oil is a seed oil rich in gamma-linolenic acid (GLA), an omega-6 fatty acid, that is popularly used for skin conditions, PMS, and breast pain. The evidence behind most of th...
Read the full Evening Primrose monograph → Herb & supplement monographBorage
Interacts with 226 drugsBorage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...
Read the full Borage monograph →Sources & How We Checked
Censor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 236 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Safflower 14 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Borkman M, Chisholm DJ, Furler SM, et al. Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM. Diabetes 1989;38:1314-9.. PubMed
- Amato, P. and Quercia, R. A. A historical perspective and review of the safety of lipid emulsion in pregnancy. Nutr Clin Pract. 1991;6(5):189-192. PubMed
- Demke, D. M., Peters, G. R., Linet, O. I., Metzler, C. M., and Klott, K. A. Effects of a fish oil concentrate in patients with hypercholesterolemia. Atherosclerosis 1988;70(1-2):73-80. PubMed
- Kaji, K., Yoshida, S., Nagata, N., Yamashita, T., Mizukoshi, E., Honda, M., Kojima, Y., and Kaneko, S. An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C. J Gastroenterol. 2004;39(9):873-878. PubMed
- Kwon, J. S., Snook, J. T., Wardlaw, G. M., and Hwang, D. H. Effects of diets high in saturated fatty acids, canola oil, or safflower oil on platelet function, thromboxane B2 formation, and fatty acid composition of platelet phospholipids. Am.J.Clin.Nutr. PubMed
- Lloyd-Still, J. D., Simon, S. H., Wessel, H. U., and Gibson, L. E. Negative effects of oral fatty acid supplementation on sweat chloride in cystic fibrosis. Pediatrics 1979;64(1):50-52. DOI
- Challen, A. D., Branch, W. J., and Cummings, J. H. The effect of aspirin and linoleic acid on platelet aggregation, platelet fatty acid composition and haemostasis in man. Hum Nutr Clin Nutr 1983;37(3):197-208.
- Asp ML, Collene AL, Norris LE, Cole RM, Stout MB, Tang SY, Hsu JC, Belury MA. Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: a randomized, double-masked, cro
- Liu Y, Liu S, Shi Y, et al. Effects of safflower injection on the pharmacodynamics and pharmacokinetics of warfarin in rats. Xenobiotica. 2017 Oct 25:1-6. [Epub ahead of print] PubMed
- de Ataide EC, Reges Perales S, de Oliveira Peres MA, et al. Acute liver failure induced by Carthamus tinctorius oil: Case reports and literature review. Transplant Proc. 2018;50(2):476-477. PubMed
- Ruyvaran M, Zamani A, Mohamadian A, et al. Safflower (Carthamus tinctorius L.) oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. PubMed
Fish Oil 157 references
- Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
- Allard JP, Kurian R, Aghdassi E, Muggli R, et al. Lipid peroxidation during n-3 fatty acid and vitamin E supplementation in humans. Lipids 1997;32:535-41.. PubMed
- Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
- Onwude JL, Lilford RJ, Hjartardottir H, et al. A randomised double blind placebo controlled trial of fish oil in high risk pregnancy. Br J Obstet Gynaecol 1995;102:95-100. PubMed
- Bulstra-Ramakers MT, Huisjes HJ, Visser GH. The effects of 3g eicosapentaenoic acid daily on recurrence of intrauterine growth retardation and pregnancy induced hypertension. Br J Obstet Gynaecol 1995;102:123-6. PubMed
- Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
- Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
- Hawthorne AB, Daneshmend TK, Hawkey CJ, et al. Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomised controlled trial. Gut 1992;33:922-8. PubMed
- D'Almeida A, Carter JP, Anatol A, Prost C. Effects of a combination of evening primrose oil (gamma linolenic acid) and fish oil (eicosapentaenoic + docahexaenoic acid) versus magnesium, and versus placebo in preventing pre-eclampsia. Women Health 1992;19 PubMed
- FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
- Montori VM, Farmer A, Wollan PC, Dinneen SF. Fish oil supplementation in type 2 diabetes: a quantitative systemic review (abstract). Diabetes Care 2000;23:1407-15.
- Anon. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Soprawivenza nell'Infarto miocardico. Lancet 1999;354:447-55. DOI
- Adler A, Holub BJ. Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men. Am J Clin Nutr 1997;65:445-50. PubMed
- Higdon JV, Liu J, Du S, et al. Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as asses
- Kastrup EK. Drug Facts and Comparisons. 1998 ed. St. Louis, MO: Facts and Comparisons, 1998.
- Belluzzi A, Brignola C, Campieri M, et al. Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. N Engl J Med 1996;334:1557-60. PubMed
- Belluzzi A, Brignola C, Campieri M, et al. Effects of new fish oil derivative on fatty acid phospholipid-membrane pattern in a group of Crohn's disease patients. Dig Dis Sci 1994;39:2589-94. PubMed
- Mahan LK, Escott-Stump S. Krause's Food, Nutrition, and Diet Therapy. 9th edition. W.B. Saunders Co., Philadelphia, PA, 1996.
- Yetiv JZ. Clinical applications of fish oils. JAMA 1988;260:665-70. DOI
- de Deckere EAM, Korver O, Verschuren PM, Katan MB. Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. Eur J Clin Nutr 1998;52:749-53. PubMed
- Sorensen NS, Marckmann P, Hoy CE, et al. Effect of fish-oil-enriched margarine on plasma lipids, low-density-lipoprotein particle composition, size, and susceptibility to oxidation. Am J Clin Nutr 1998;68:235-41. PubMed
- Kelley DS, Rudolph IL. Effect of individual fatty acids of omega-6 and omega-3 type on human immune status and role of eicosanoids. Nutrition 2000;16:143-5.
- Meydani SN, Dinarello CA. Influence of dietary fatty acids on cytokine production and its clinical implications. Nutr Clin Pract 1993;8:65-72. PubMed
- Caicoya M. Fish consumption and stroke: a community case-control study in Asturias, Spain. Neuroepidemiology 2002;21:107-14. PubMed
- Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
- Dewailly E, Blanchet C, Lemieux S, et al. n-3 Fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik. Am J Clin Nutr 2001;74:464-73. PubMed
- Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
- Maresta A, Balduccelli M, Varani E, et al. Prevention of postcoronary angioplasty restenosis by omega-3 fatty acids: main results of the Esapent for Prevention of Restenosis Italian Study (ESPRIT). Am Heart J 143:E5. PubMed
- Deutch B, Jorgensen EB, Hansen JC. n-3 PUFA from fish or seal oil reduce atherogenic risk indicators in Danish women. Nutr Res 2000;20:1065-77. DOI
- Higgins S, McCarthy SN, Corridan BM, et al. Measurement of free cholesterol, cholesteryl esters and cholesteryl linoleate hydroperoxide in copper-oxidised low density lipoprotein in healthy volunteers supplemented with a low dose of n-3 polyunsaturated f
- Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
- Lacaille B, Julien P, Deshaies Y, et al. Responses of plasma lipoproteins and sex hormones to the consumption of lean fish incorporated in a prudent-type diet in normolipidemic men. J Am Coll Nutr 2000;19:745-53. PubMed
- Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
- Higdon JV, Du SH, Lee YS, et al. Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate. J Lipid Res 2001;42:407-18. DOI
- Olsen SF, Sorensen JD, Secher NJ, et al. Randomised controlled trial of effect of fish-oil supplementation on pregnancy duration. Lancet 1992;339:1003-7. PubMed
- Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
- Bender NK, Kraynak MA, Chiquette E, et al. Effects of marine fish oils on the anticoagulation status of patients receiving chronic warfarin therapy. J Thromb Thrombolysis 1998;5:257-61.. PubMed
- Suzukawa M, Abbey M, Howe PR, Nestel PJ. Effects of fish oil fatty acids on low density lipoprotein size, oxidizability, and uptake by macrophages. J Lipid Res 1995;36:473-84.. DOI
- Su KP, Huang SY, Chiu CC, Shen WW. Omega-3 fatty acids in major depressive disorder. A preliminary double-blind, placebo-controlled trial. Eur Neuropsychopharmacol 2003;13:267-71..
- Wang C, Chung M, Lichtenstein A, et al. Effects of omega-3 fatty acids on cardiovascular disease. Evid Rep Technol Assess (Summ) 2004 Mar;(94):1-8.
- US Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Seafood. Mercury levels in seafood species. Available at: http://www.cfsan.fda.gov/~frf/sea-mehg.html.
- US Environmental Protection Agency. Fish Advisories web page. Available at: http://www.epa.gov/waterscience/fish.
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