Extend Plus By Vitamin Research Products Overview & Drug Interactions

Vitamin D is a fat-soluble vitamin that plays a crucial role in several bodily processes. It helps the body absorb calcium and phosphorus, which are necessary for healthy bones and teeth. It is also important for immune system function and may help to protect against certain diseases. Vitamin D is found in a variety of foods, including fatty fish, egg yolks, and fortified foods such as milk and cereal. It is also produced by the body when the skin is exposed to sunlight. Vitamin D supplements are available in a variety of forms, including tablets, capsules, and liquids. The recommended daily intake of vitamin D varies depending on age, sex, and other factors, and it is important to follow the dosage recommendations provided by a healthcare professional. There are several different forms of vitamin D available, with the two most popular being ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3).

Vitamin E is a fat-soluble vitamin found naturally in a variety of foods, including vegetable oils, nuts, seeds, and leafy green vegetables. Vitamin E is also available as a dietary supplement and is often added to skincare products. Vitamin E has many roles in the body, including protecting cells from oxidative stress and supporting immune function.

Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Folate and folic acid are forms of vitamin B9, essential for health. Folate occurs naturally in foods like leafy vegetables, legumes, and fruits, while folic acid is the synthetic form used in supplements and fortified foods. Since 1998, the US has fortified cereals, baking flour, pasta, and bakery items with folic acid to prevent deficiencies. Naturally occurring folate, or pteroylpolyglutamate, has lower bioavailability (40% to 50%) compared to nearly 100% for synthetic folic acid. Foods rich in folate include asparagus, mushrooms, yeast, legumes, spinach, broccoli, lettuce, bananas, melons, oranges, tomatoes, lemons, and animal products like beef liver and kidney. Some supplements contain L-5-methyltetrahydrofolate (L-5-MTHF), a reduced folate form. L-5-MTHF, dependent on vitamin B12 for metabolism, is absorbed faster and more effectively than folic acid, especially in individuals with specific MTHFR genotypes. Studies show that women taking L-5-MTHF had slightly higher red blood cell folate concentrations compared to those taking folic acid, although long-term use results in similar blood levels and effectiveness for preventing neural tube defects.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.

Biotin, also known as vitamin H or vitamin B7, is a water-soluble vitamin that plays a role in various metabolic processes in the body. It is necessary for the growth and maintenance of healthy skin, hair, and nails, and is also involved in the metabolism of carbohydrates, fats, and amino acids. Biotin is considered to be generally safe when consumed in the recommended daily amounts but it is important to note that consuming large amounts of biotin-containing supplements or products can cause falsely high or falsely low test results for certain laboratory tests, such as those for thyroid function, hormone levels, and certain biomarkers for certain diseases.

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Iodine is a mineral that is crucial for our body's ability to produce thyroid hormone, which helps control our growth, metabolism, and energy levels. A lack of iodine in the diet is a common problem around the world and can lead to intellectual development issues. Adding iodine to salt (i.e., iodized salt) has helped reduce this problem. Iodine is commonly utilized as a dietary supplement, both in multivitamin preparations and as a standalone ingredient as it is purported to have overall health and wellness benefits, not just in those who are deficient. One such standalone iodine product is 'Iodoral'. Studies have shown iodine supplementation may help improve cognitive function and boost energy levels but more research is needed. It is recommended that you should be under medical supervision if you plan on taking iodine as there may be a risk of certain side effects with high dosages.

Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement. There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines. Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.

Zinc is a mineral that is essential for the proper functioning of the human body. It is involved in many important physiological processes, including immune system function, wound healing, taste, and smell. Zinc is found in a variety of foods, including meat, seafood, and whole grains, and it is also available as a dietary supplement. Zinc supplements may be used to treat or prevent zinc deficiency, which can occur due to certain medical conditions, such as gastrointestinal disorders, alcohol abuse, and certain medications. Zinc supplements may also be used for other purposes, such as to boost the immune system, improve acne, and reduce the severity and duration of colds. There are several different forms of zinc supplements available, including zinc gluconate, zinc acetate, and zinc sulfate. The most common form of zinc supplements is zinc gluconate, which is well absorbed and is less likely to cause stomach-related side effects than other forms of zinc.

Selenium is an essential trace element that plays a crucial role in various physiological functions in the human body. It is often included in dietary supplements due to its antioxidant properties and its contribution to maintaining a healthy immune system. Selenium is important for thyroid function and may also have a role in protecting against certain chronic diseases. However, it's essential to note that excessive selenium intake can be harmful, so it's crucial to adhere to recommended daily allowances and consult with a healthcare professional before taking selenium supplements.

Manganese is an essential trace mineral that plays a vital role in various physiological processes within the human body. It is required for proper brain function, bone formation, enzyme activation, and wound healing. Manganese also contributes to metabolism, antioxidant defense, and the formation of connective tissues.

Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control. There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.

N-acetyl cysteine (NAC) is derived from the amino acid cysteine. It is used as a prescription medication to treat acetaminophen overdose and to help thin mucus in people with certain respiratory conditions. It is also used as a dietary supplement. NAC has a number of potential health benefits. It is a source of the antioxidant enzyme glutathione, which is important for protecting cells from oxidative stress and supporting immune function. It also may have anti-inflammatory effects and studies show it may support healthy brain function. It is generally considered safe to take NAC supplements in recommended doses.

Alpha-lipoic acid (ALA) is a naturally occurring compound that is made by the body and is also found in some foods, such as spinach, broccoli, and potatoes. It plays a role in energy production in the body and acts as an antioxidant, helping to protect cells from damage caused by free radicals. ALA has been studied for its potential health benefits, including the treatment of certain types of nerve damage, diabetes, and liver disease.

Quercetin is a type of flavonoid, which is a class of compounds found in a wide variety of plants and foods. It is purported to have a number of health benefits such as anti-inflammatory, antioxidant, and immune-boosting effects. Studies suggest it may also help to reduce the risk of certain chronic diseases, such as heart disease. In addition, quercetin may have anti-allergic properties and may be helpful in the treatment of allergies and asthma. It is a popular dietary supplement worldwide and is often included in products that contain antioxidants or various vitamins/minerals. Its wide range of potential health benefits mean that it could potentiate the effects of other drugs (e.g., anti-hypertensives), which is why there are an abundant number of potential interactions listed for quercetin.

Lycopene is a natural red pigment and powerful antioxidant found in various fruits and vegetables, notably in tomatoes, watermelon, guava, and grapefruit. It belongs to the carotenoid family and is responsible for the vibrant red color in these foods. Studies suggest that lycopene may have health benefits, including reducing the risk of chronic diseases, such as heart disease and certain types of cancer, due to its antioxidant properties. It is best absorbed by the body when consumed with fats or oils.

Choline is an essential nutrient that is found in many foods, including eggs, and is important for a number of bodily functions, including liver function, brain development, and nerve function. Choline is a precursor to acetylcholine, a neurotransmitter that plays a role in memory, mood, and muscle control. Choline also helps to transport fats out of the liver, which may help to reduce the risk of liver disease. Choline supplements are available in different forms, including choline bitartrate, choline chloride, and phosphatidylcholine. Choline bitartrate is the most common form of choline supplement, but phosphatidylcholine is the form that is found naturally in foods.

Inositol is a type of carbohydrate (sugar alcohol) that is found in a variety of foods, including fruits, nuts, and grains. It is also known as vitamin B8 but is not considered 'essential' as it can be synthesized in the human body. Inositol is involved in a number of important physiological processes, including the metabolism of fats, the regulation of insulin, and the transmission of nerve impulses. Inositol is a popular dietary supplement and is believed to have a number of potential health benefits. It is thought to have a role in the treatment of certain mental health conditions, is believed to have a positive effect on cholesterol levels and may be helpful in the prevention or management of heart disease. In addition, inositol may have anti-inflammatory effects and may be helpful in the treatment of certain skin conditions.

Inositol is a type of carbohydrate (sugar alcohol) that is found in a variety of foods, including fruits, nuts, and grains. It is also known as vitamin B8 but is not considered 'essential' as it can be synthesized in the human body. Inositol is involved in a number of important physiological processes, including the metabolism of fats, the regulation of insulin, and the transmission of nerve impulses. Inositol is a popular dietary supplement and is believed to have a number of potential health benefits. It is thought to have a role in the treatment of certain mental health conditions, is believed to have a positive effect on cholesterol levels and may be helpful in the prevention or management of heart disease. In addition, inositol may have anti-inflammatory effects and may be helpful in the treatment of certain skin conditions.

Green tea is a type of tea that is made from the leaves of the Camellia sinensis plant. It is native to Asia and is widely consumed throughout the world. Green tea has a mild, slightly grassy flavor and is typically lighter in color and less astringent than black tea. Green tea is a rich source of antioxidants, particularly a group of compounds called catechins. These antioxidants are thought to help protect cells from damage caused by free radicals. Green tea is also a good source of other nutrients, including vitamin C and several B vitamins. Green tea is often consumed for a number of purported health benefits including reducing the risk of heart disease, immune-stimulating effects, and weight loss. Oral green tea supplements, containing dried powder, are most often utilized for the caffeine content and used as an appetite suppressant for weight loss.

Bamboo, a type of giant grass, encompasses over 1,000 species in dozens of genera, primarily found in Asia. The plant's shoots are harvested for food and medicine, offering protein, carbohydrates, and vitamins. Bamboo shoot preparation is crucial, as they contain cyanogenic glycosides, which, when converted to hydrogen cyanide, can be toxic. Proper boiling or fermentation eliminates cyanide, rendering bamboo shoots safe to eat. Limited research suggests potential anti-cancer effects from bamboo leaf extract, but more studies are needed. Additionally, bamboo extracts have shown thyroid effects in laboratory and animal studies, inhibiting thyroid peroxidase activity and potentially leading to hypothyroidism.

Boron is a trace mineral that is found in a variety of foods, including fruits, vegetables, nuts, and legumes. It is also available as a dietary supplement. Boron is thought to play a role in bone health, as it may help the body metabolize calcium, magnesium, and phosphorus. Some preliminary research also suggests that boron may have anti-inflammatory effects and may help to improve cognitive function. However, more research is needed to confirm these potential benefits. It is important to note that boron is not an essential nutrient and deficiency is rare. The recommended dietary allowance (RDA) for boron is not established, however, the safe upper limit is 20mg/day. Taking high doses of boron can cause skin irritation, nausea, vomiting, and diarrhea. There are several patented forms of boron available in dietary supplements, such as Albion Bororganic Glycine.

Vanadium is a chemical element with the symbol V and atomic number 23. It is a soft, silvery-grey metal that is found in small amounts in various minerals and rocks. Vanadium is used in a variety of industrial applications, including the production of steel and as a chemical catalyst. Vanadium is an essential trace mineral that is required by the body in small amounts for proper growth and development. The human body does not naturally produce it. It is involved in several important biological processes, including the metabolism of carbohydrates and the synthesis of proteins and DNA. Vanadium supplements are sometimes marketed as a way to improve athletic performance, lower cholesterol levels, and manage diabetes. However, there is limited scientific evidence to support the use of vanadium supplements for these purposes and high levels of vanadium can be toxic. It must be used cautiously.