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Dietary supplement

Eyebright Ingredients & Drug Interactions

by Herb Pharm

Eyebright label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eyebright against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eyebright is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for eye irritation and redness, conjunctivitis (pink eye), eye strain.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are EYEBRIGHT. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Eyebright by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Eyebright by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Eyebright by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

Herb Pharm Eyebright is a liquid herbal supplement containing one active ingredient: eyebright. It's prepared using grain alcohol and distilled water as the extraction medium, plus eyebright extractives.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Eyebright's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: eye health and comfort.
  • We looked for evidence on: Asthenopia (eye strain), Conjunctivitis, Allergic rhinitis (hay fever), eye irritation, eye redness, nasal congestion.
  • The closest evidence on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Asthenopia (eye strain), Conjunctivitis.

The evidence on eyebright isn't established for the conditions it's traditionally used for. Our data shows insufficient reliable evidence to rate it for allergic rhinitis (hay fever), cancer, common cold, cough, pharyngitis, and rhinosinusitis.

The evidence, ingredient by ingredient Eyebright

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eyebright is likely well tolerated in small amounts as a tea taken by mouth. However, applying homemade or non-sterile preparations directly in the eye carries risk and isn't recommended.

Some people have reported confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion when taking it orally. Safety data during pregnancy advises against use.

There isn't enough information to know whether it's safe while breastfeeding — talk with your doctor or pharmacist for personalized guidance if you're nursing.

Side effects, ingredient by ingredient Eyebright

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eyebright.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drugs or insulin to control your blood sugar, check your specific medications before starting Eyebright — it may lower blood glucose and raise the risk of low blood sugar (a Moderate severity interaction).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Eyebright is traditionally used for eye and respiratory symptoms, but the evidence supporting its effectiveness isn't established in our data. If you take blood-sugar medication, you'll want to check your specific drugs before starting this product because of a documented interaction risk.

Talk with your doctor or pharmacist about whether it's right for you and whether it makes sense alongside your current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eyebright, straight from the product label.

Brand Herb Pharm
Net contents 8 fl. Oz.
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 23546
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eyebright by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Drop(s)
Maximum serving Sizes:
40 Drop(s)
IngredientAmount% DV
EYEBRIGHT0 NP--

Other ingredients: grain alcohol, distilled Water, Eyebright extractives

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE Shake Well Before Using Two to five times per day take 30 to 40 drops in a little water.

Shake Well Before Dispensing From This Bottle

Precautions

Keep Out of the Reach of Children

General

003

General Statements

LIQUID HERBAL EXTRACT

To assure optimal extraction of Eyebright's bioactive compounds, the plants are hand-harvested ony while in full flower, and are then taken directly to our laboratory and promptly extracted while still fresh and succulent. Our Eyebright is never fumigated or irradiated.

110274-1M14

FDA Statement of Identity

HERBAL DIETARY SUPPLEMENT

Brand IP Statement(s)

We prepare our Eyebright Extract from fresh (undried) Euphrasia officinalis plants which are Custom Wildcrafted(TM) in their natural wild habitat.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eyebright by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eyebright label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eyebright by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size30 Drop(s) Dosage formLiquid Amounts shown are per serving.

EYEBRIGHT

Interacts with
86 drugs
0 NP per serving

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. Th...

EYEBRIGHT monograph & interactions

Other (inactive) ingredients: Grain alcohol, Distilled Water, Eyebright extractives. These complete the product’s ingredient list but are not active constituents.

Interaction report

Eyebright by Herb Pharm Drug Interactions

Want to check YOUR meds against Eyebright?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

EYEBRIGHT 86

Individual Drug Interactions

The ingredients in Eyebright interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Eyebright interact with drugs. Each result below shows which ingredient is responsible. EYEBRIGHT

Each ingredient & the kinds of drugs it affects

For each ingredient in Eyebright with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

EYEBRIGHT1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.

Likelihood Possible Evidence D
EYEBRIGHT full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eyebright, from the product label.

Herb Pharm

See all Herb Pharm products
Name
HERB PHARM
City
WILLIAMS
State
OR
ZipCode
97544
Pharmacist Counseling Corner

Eyebright by Herb Pharm: Common Questions

Does Eyebright by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Eyebright has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eyebright contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use Eyebright while pregnant or breastfeeding?
Safety data advises against use during pregnancy. If you're breastfeeding, there isn't enough information to know either way — talk with your doctor or pharmacist for personalized advice.
What are the side effects of Eyebright?
People taking it orally have reported confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion. Never apply it directly in the eye unless it's a sterile, commercial preparation — homemade or non-sterile eye use is risky.
Does Eyebright actually work for hay fever or colds?
The evidence isn't established in our data. While it's used traditionally for allergic rhinitis, common cold, cough, and other respiratory conditions, we can't rate how well it works for any of them.
What is eyebright used for?
It's a traditional herbal remedy for eye health and respiratory symptoms like hay fever and cough, though scientific evidence for these uses isn't established.
Is this product safe to take with my blood-sugar medication?
That depends on your specific medication — eyebright may lower blood glucose levels and raise the risk of low blood sugar when combined with antidiabetes drugs. Check your exact medications with the tool on this page, then talk it over with your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eyebright label
Go deeper

The Full Monographs Behind Eyebright’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eyebright

Interacts with 86 drugs

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to c...

Read the full Eyebright monograph →
Sources

Sources & How We Checked

Eyebright's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eyebright 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

See these in context on the Eyebright monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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