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Dietary supplement

Flexuron Ingredients & Drug Interactions

by Purity Products

Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Flexuron is a dietary supplement by Purity Products with 3 active ingredients. Its ingredients are commonly taken for heart and cholesterol support, high triglycerides, joint pain and inflammation.Based on those ingredients, 838 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Zanthin Natural Astaxanthin, Krill (Euphausia superba) Phospholipid-Rich Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Flexuron by Purity Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Flexuron Proprietary Patented Joint Comfort Blend” is a proprietary blend — the label gives one combined amount (32 mg) without saying how much of each component you get.

Flexuron has three active ingredients. Krill oil — a phospholipid-rich extract from Antarctic krill — provides omega-3 fatty acids.

Low molecular weight hyaluronic acid supports joint and skin hydration. Astaxanthin, a natural carotenoid from algae (Zanthin brand), is an antioxidant.

The product also contains a proprietary joint comfort blend whose individual components are listed separately in the full ingredient panel. Beyond these actives, the capsule itself is gelatin-based and includes olive oil, sorbitol, glycerin, purified water, beeswax, ethyl vanillin, and spice extract as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: daily joint care and comfort.
  • We looked for evidence on: Osteoarthritis, Carpal tunnel syndrome, Rheumatoid arthritis (RA), joint pain, joint inflammation, joint stiffness.
  • The closest evidence on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Carpal tunnel syndrome, Osteoarthritis, Rheumatoid arthritis (RA).
  • Also on file: Krill Oil is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis, Rheumatoid arthritis (RA).

Evidence for Flexuron's ingredients is mixed. Krill oil is possibly effective for dry eye, but evidence for aging skin, Alzheimer's, cancer, high cholesterol, and cognitive function is insufficient.

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (open skin wounds), though evidence for aging skin, hay fever, and sexual dysfunction is insufficient. Astaxanthin's evidence for age-related macular degeneration, Alzheimer's, aging skin, athletic performance, carpal tunnel, and age-related cognitive decline is all insufficient.

The effectiveness of the proprietary blend itself isn't addressed in the data we hold.

The evidence, ingredient by ingredient Krill Oil Hyaluronic Acid Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Krill oil is generally well tolerated at doses up to 4 grams daily. Most common side effects are gastrointestinal — bloating, decreased appetite, diarrhea, fishy burps, flatulence, heartburn, nausea, and stomach discomfort — though these tend to be milder with krill oil than with fish oil.

Rarely, headache, tiredness, and dizziness have been reported. Avoid krill oil if you have a shellfish allergy, and use caution if you have a bleeding disorder.

Hyaluronic acid is generally well tolerated, though long-term safety data are limited; the safety data advise against oral supplements during pregnancy and lactation unless your doctor clears it. Astaxanthin is generally well tolerated in studies, though long-term safety data are limited; the safety data advise against it during pregnancy and breastfeeding.

Common side effects from astaxanthin include abdominal pain, diarrhea, and red-colored stools; at very high doses (40 mg daily), severe stomach pain has occurred in a small number of trial participants. Krill oil also lacks enough safety data during pregnancy and breastfeeding — talk to your doctor before using during either.

Side effects, ingredient by ingredient Krill Oil Hyaluronic Acid Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Astaxanthin, Krill Oil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 839 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Flexuron, double-check with your pharmacist or doctor if you take blood thinners or antiplatelet drugs like warfarin or aspirin (krill oil may increase bleeding risk), diabetes medications (krill oil might lower blood sugar further), or any drug processed through your liver's CYP3A4 or CYP2B6 pathways — astaxanthin may reduce their levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Flexuron may appeal to people interested in joint and skin support, but the evidence for most of those uses is still developing. If you take blood thinners, diabetes medications, or drugs processed through your liver's CYP3A4 or CYP2B6 pathways, check with your pharmacist or doctor before starting — it's a must.

Pregnant or breastfeeding? Talk it over with your doctor first; the data aren't solid enough to be sure either way.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Flexuron, straight from the product label.

Brand Purity Products
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 243750
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Flexuron by Purity Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
IngredientAmount% DV
Krill (Euphausia superba) Phospholipid-Rich Oil321 mg--
Flexuron Proprietary Patented Joint Comfort Blend32 mg--
Low Molecular Weight Hyaluronic Acid0 NP--
Zanthin Natural Astaxanthin0 NP--

Other ingredients: Gelatin, Olive Oil, Sorbitol, Glycerin, purified Water, Beeswax, Ethyl Vanillin, Spice Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Start working in just 7 days

Daily joint care

On average 3X better than glucosamine & chondroitin for promoting maximum, total joint comfort

General Statements

Just 1 tiny Flexuron softgel

2 glucosamine & chondroitin tablets

Intelligent nutritional solutions

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take 1 softgel daily. For the first two weeks, take 1 softgel twice daily as needed. For daily use.

Precautions

Contains shellfish (krill).

Brand IP Statement(s)

Zanthin is a registered trademark of Valensa International U.S. Patents 8,841,072 and 8,524,980.

See for yourself

Flexuron by Purity Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Flexuron by Purity Products

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

321 mg per serving

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...

Krill (Euphausia superba) Phospholipid-Rich Oil monograph & interactions

Flexuron Proprietary Patented Joint Comfort Blend

32 mg per serving

Other (inactive) ingredients: Gelatin, Olive Oil, Sorbitol, Glycerin, Purified Water, Beeswax, Ethyl Vanillin, Spice Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Flexuron by Purity Products Drug Interactions

Want to check YOUR meds against Flexuron?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
838Drugs
838 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Flexuron with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Zanthin Natural Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D

Krill (Euphausia superba) Phospholipid-Rich Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Flexuron, from the product label.

Purity Products

See all Purity Products products
Name
Purity Products
Pharmacist Counseling Corner

Flexuron by Purity Products: Common Questions

Does Flexuron by Purity Products interact with any medications?
Yes. Based on its ingredients, Flexuron has a known interaction with 838 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Flexuron contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any shellfish?
Yes. Krill oil comes from Antarctic krill, a shellfish-like crustacean. If you have a shellfish allergy, avoid this product.
Can I take it if I'm pregnant or breastfeeding?
The safety data for krill oil, hyaluronic acid, and astaxanthin aren't solid enough during pregnancy or breastfeeding. Talk to your doctor before using — they can weigh the risks and benefits for your situation.
What are the most common side effects?
Krill oil most often causes mild stomach issues: bloating, decreased appetite, diarrhea, fishy burps, flatulence, heartburn, nausea, and stomach discomfort. Astaxanthin can cause abdominal pain, diarrhea, and red-colored stools. These effects are usually mild and seem less frequent with krill oil than with fish oil alone.
Is this product studied for joint health?
The product contains a proprietary joint comfort blend, but the effectiveness data we hold cover individual ingredients, not the blend itself. The individual ingredients' evidence for joint support is either insufficient or not listed in the data.
Can I take it with my blood thinner?
Don't start without asking your pharmacist or doctor. Krill oil in Flexuron may increase bleeding risk when combined with blood thinners or antiplatelet drugs — the interaction is real and worth checking before you begin.
How much krill oil is in each capsule?
The product facts don't specify the dose of each ingredient per capsule — check the label or manufacturer's site for that detail.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Flexuron is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Flexuron label
Sources

Sources & How We Checked

Flexuron's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Krill Oil 13 references
  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

See these in context on the Krill Oil monograph →

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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