Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Raspberry Keytones+ Ingredients & Drug Interactions

by Purely Inspired

Raspberry Keytones+ label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Raspberry Keytones+ against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Raspberry Keytones+ is a dietary supplement by Purely Inspired with 2 active ingredients. Its ingredients are commonly taken for weight loss, fat burning, boosting metabolism.Based on those ingredients, 591 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Green Coffee bean extract, Raspberry Ketone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Raspberry Keytones+ by Purely Inspired

Ask about any prescription or over-the-counter medication and we check it for interactions with Raspberry Keytones+ by Purely Inspired — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Raspberry Keytones+ by Purely Inspired

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Raspberry Keytones+ contains 2 active ingredients: raspberry ketone and green coffee bean extract. Raspberry ketone is a compound found in raspberries; green coffee bean extract is made from unroasted coffee beans and contains caffeine.

The product also includes several inactive ingredients—microcrystalline cellulose, dicalcium phosphate dihydrate, hydroxypropylcellulose, magnesium stearate, stearic acid, croscarmellose sodium, silicon dioxide, and a vegetable-based coating—that serve as fillers, binders, and capsule materials.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: weight loss and metabolism support.
  • We looked for evidence on: Obesity, Metabolic syndrome, Fat loss, Appetite regulation.
  • The closest evidence on file: Coffee is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).
  • Also on file: Coffee is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome.
  • Also on file: Raspberry Ketone is rated "Insufficient Reliable Evidence To Rate" for Obesity.

The evidence for this product is limited. Raspberry ketone shows insufficient reliable evidence for both obesity and alopecia areata (hair loss)—we don't have enough solid data to say whether it works for these uses.

Green coffee bean extract fares better: it's likely effective for mental alertness and possibly effective for Parkinson disease, heart failure, diabetes, and overall mortality. Keep in mind that this product combines two ingredients with very different evidence profiles, so its overall benefit isn't established in our data.

The evidence, ingredient by ingredient Raspberry Ketone Coffee

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Raspberry ketone has been used in foods safely, but human safety data for the high doses in supplements is very limited. Because it structurally resembles a known stimulant, it can cause heart palpitations, elevated blood pressure, abnormal heart rhythms, sweating, diarrhea, and shakiness—though these aren't well studied.

Green coffee bean extract (caffeine) is generally well tolerated in moderate amounts but can cause agitation, anxiety, chest pain, headache, insomnia, nervousness, rapid heartbeat, ringing in the ears, and vomiting, especially at higher intakes or in children and older adults. With long-term heavy caffeine use, dependence and withdrawal symptoms may occur.

Caffeine can rarely trigger anaphylaxis in sensitive people.

Side effects, ingredient by ingredient Raspberry Ketone Coffee

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Coffee, Raspberry Ketone.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 591 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Raspberry Keytones+, double-check with your doctor or pharmacist if you take ephedrine (a Major-severity interaction risk), stimulant drugs, warfarin or other blood thinners, or any of these medications: cimetidine, disulfiram, dipyridamole, clozapine, lamotrigine, pentobarbital, or fluvoxamine. The caffeine in green coffee bean extract can also raise the effects of several of these drugs or lower the effectiveness of others, so it's important to confirm everything is safe to combine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This product may appeal to someone looking for mental alertness support (from the green coffee bean extract) or general wellness, but the evidence for weight loss is insufficient. If you take stimulant drugs, blood thinners like warfarin, or any of the medications listed in the med_watch section below, you'll need to clear this product with your own doctor or pharmacist first—the interactions can be serious.

Pregnant or breastfeeding? Check with your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Raspberry Keytones+, straight from the product label.

Brand Purely Inspired
Barcode (UPC) 631656604771
Net contents 100 Easy to Swallow Tablet(s)
Market status On market
Date entered into DSLD Mar 24, 2016
DSLD ID 57419
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Raspberry Keytones+ by Purely Inspired, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Easy to Swallow Tablet(s)
Maximum serving Sizes:
3 Easy to Swallow Tablet(s)
Servings per container
33
UPC/BARCODE
631656604771
IngredientAmount% DV
Raspberry Ketone600 mg--
Green Coffee bean extract200 mg--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate Dihydrate, Hydroxypropylcellulose, Magnesium Stearate, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Vegetable-Based Coating

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bonus 60 Tabs + 40 free

~ Green coffee is backed by 2 scientific weight loss studies*

The 100% Quality Commitment

Get the formula you want!

Hottest Ingredient! Raspberry ketone is an aromatic compound found in raspberries that produces the distinctive fruity raspberry scent.

The key weight loss ingredient – green coffee – is backed by two scientific studies.*

Powerful Formula

Backed by 2 Scientific Weight Loss Studies *Average weight loss with key ingredient (200mg of standardized green coffee bean extract) was 10.95 lbs. in a 60-day study with a low-calorie diet, and 3.7 lbs. in a separate 8-week study with a calorie-reduced diet and moderate exercise.

FROM THE MAKERS OF AMERICA’S #1 SELLING WEIGHT LOSS SUPPLEMENT BRAND

LOSE WEIGHT with Green Coffee

Iovate Health Sciences also makes America’s #1 Selling Weight Loss Supplement Brand, based on IRI FDMx sales data.

Made in the U.S.A. from international ingredients.

100% Pure

Brand IP Statement(s)

Purely Inspired vs. Leading Competitor {chart} 600mg per serving Purely Inspired 1000mg per serving Leading competitor 2-pack

Why Purely Inspired Raspberry Ketones+

New Purely Inspired Raspberry Ketones+ is subject to quality controls.

Get new Purely Inspired Raspberry Ketones+ today!

Unlike other products, Purely Inspired weight loss products are made with 100% pure, premium ingredients you can trust.

“I highly recommend Purely Inspired weight loss products to effectively help people lose weight.” – Jenette T. Swisher, MD

2015.

Formula

~ Contains 5X more raspberry ketone per serving than the leading competitor ~ Made with 100% pure ingredients

5x MORE RASPBERRY KETONE per serving than the leading competition

100% Pure Raspberry Ketones+ with Green Coffee for Weight Loss

Purely Inspired Raspberry Ketones+ delivers 200mg of green coffee extract per serving for weight loss results, plus 600mg of the hot ingredient raspberry ketone.

600mg per serving of Raspberry Ketone

Seals/Symbols

TRIPLE CHECK 100% QUALITY COMMITMENT QUALITY PURITY SCIENCE

MADE IN THE USA FROM INTERNATIONAL INGREDIENTS

General

10394US 0215

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

DIRECTIONS: Take 1 serving (3 Easy-to-Swallow tablets) 2 times daily 30 to 60 minutes before your two largest meals.

Combine with diet and exercise. Read the entire label before use and follow directions provided.

Precautions

Do not snack between meals or before bed.

WARNING: For adult use only.

Do not use if pregnant or nursing.

Consult a doctor before use if you have a medical condition and before starting a diet or exercise program.

KEEP OUT OF REACH OF CHILDREN.

Do not use if packaging has been tampered with.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool, dry place 60(0)F to 80(0)F).

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Raspberry Keytones+ by Purely Inspired label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Raspberry Keytones+ label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Raspberry Keytones+ by Purely Inspired

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Easy to Swallow Tablet(s) Dosage formTablet Or Pill Servings per container33 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Raspberry Ketone

Interacts with
174 drugs
600 mg per serving

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence th...

Raspberry Ketone monograph & interactions

Green Coffee bean extract

Interacts with
591 drugs
200 mg per serving Form: Chlorogenic Acids, Coffea canephora robusta

Coffee is a widely consumed beverage made from roasted coffee beans, valued mainly for its caffeine, which boosts alertness and energy. For most healt...

Green Coffee bean extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate Dihydrate, Hydroxypropylcellulose, Magnesium Stearate, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Vegetable-Based Coating. These complete the product’s ingredient list but are not active constituents.

Interaction report

Raspberry Keytones+ by Purely Inspired Drug Interactions

Want to check YOUR meds against Raspberry Keytones+?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
591Drugs
8 Major 467 Moderate 116 Minor

Ingredients driving the most interactions

Green Coffee bean extract 591
Raspberry Ketone 174

Individual Drug Interactions

The ingredients in Raspberry Keytones+ interact with 591 drugs. Click any drug to see the details.

2 of the 2 ingredients in Raspberry Keytones+ interact with drugs. Each result below shows which ingredient is responsible. Green Coffee bean extract Raspberry Ketone

Each ingredient & the kinds of drugs it affects

For each ingredient in Raspberry Keytones+ with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Green Coffee bean extract33 drug types · 591 drugs

Ephedrine

Theoretically, concomitant use might increase the risk of stimulant adverse effects.
Coffee contains caffeine. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death. Tell patients to avoid taking caffeine with ephedrine and other stimulants.

Likelihood Probable Evidence D
Adenosine (Adenocard)

Theoretically, coffee might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Coffee contains caffeine. Caffeine is a competitive inhibitor of adenosine at the cellular level. However, caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines such as caffeine, as well as methylxanthine-containing products, be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Possible Evidence B
Alendronate (Fosamax)

Coffee reduces alendronate bioavailability.
Separate coffee ingestion and alendronate administration by two hours. Coffee reduces alendronate bioavailability by 60%.

Likelihood Probable Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, coffee may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Coffee contains caffeine. Caffeine is reported to have antiplatelet activity. Theoretically, the caffeine in coffee might increase the risk of bleeding when used concomitantly with these agents. However, this interaction has not been reported in humans. There is some evidence that caffeinated coffee might increase the fibrinolytic activity in blood.

Likelihood Unlikely Evidence D
Beta-Adrenergic Agonists

Theoretically, concomitant use of large amounts of coffee might increase cardiac inotropic effects of beta-agonists.
Coffee contains caffeine. Caffeine can increase cardiac inotropic effects of beta-agonists.

Likelihood Probable Evidence D
Cimetidine (Tagamet)

Theoretically, cimetidine might increase the effects and adverse effects of caffeine in coffee.
Coffee contains caffeine. Cimetidine can reduce caffeine clearance by 31% to 42%.

Likelihood Likely Evidence B
Clozapine (Clozaril)

Theoretically, coffee might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Coffee contains caffeine. Caffeine can increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg daily inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Researchers speculate that caffeine might inhibit CYP1A2. However, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients be more sensitive to the interaction between clozapine and caffeine.

Likelihood Possible Evidence B
Contraceptive Drugs

Theoretically, concomitant use might increase the effects and adverse effects of caffeine found in coffee.
Coffee contains caffeine. Oral contraceptive drugs can decrease caffeine clearance by 40% to 65%.

Likelihood Probable Evidence B
Dipyridamole (Persantine)

Theoretically, coffee might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Coffee contains caffeine. Caffeine is a methylxyanthine that may inhibit dipyridamole-induced vasodilation. It is recommended that methylxanthines such as caffeine, as well as methylxanthine-containing products such as coffee, be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Probable Evidence B
Disulfiram (Antabuse)

Theoretically, disulfiram might increase the risk of adverse effects from caffeine.
Coffee contains caffeine. In human research, disulfiram decreases the clearance and increases the half-life of caffeine.

Likelihood Probable Evidence B
Diuretic Drugs

Theoretically, concomitant use might increase the risk of hypokalemia.
Coffee contains caffeine. Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.

Likelihood Possible Evidence D
Estrogens

Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Coffee contains caffeine. Estrogen inhibits caffeine metabolism.

Likelihood Probable Evidence B
Fluvoxamine (Luvox)

Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Coffee contains caffeine. Fluvoxamine reduces caffeine metabolism.

Likelihood Probable Evidence B
Lamotrigine (Lamictal)

Coffee consumption can decrease the levels and clinical effects of lamotrigine.
A pharmacokinetic study in patients taking lamotrigine shows that consumption of coffee, both caffeinated and decaffeinated, can decrease the area under the concentration-time curve (AUC) and the peak plasma level (Cmax) of lamotrigine. Each additional cup of coffee reduced the AUC and Cmax by 4% and 3%, respectively. It is unclear whether this interaction is due to induction of lamotrigine metabolism or inhibition of lamotrigine absorption.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Coffee can reduce the absorption of levothyroxine.
In some patients, coffee can reduce levothyroxine absorption, possibly through the formation of non-absorbable complexes. A pharmacokinetic study in these patients found that 25-30 mL of espresso coffee consumed with levothyroxine tablets delayed the time to peak plasma levels by 38-43 minutes, reduced the peak plasma level (Cmax) by 19% to 36%, and reduced the area under the curve (AUC) by 27% to 36%. Coffee consumed one hour after levothyroxine did not affect absorption. It is not known whether this interaction occurs with other types of coffee. Tell patients to avoid drinking coffee at the same time that they take their levothyroxine, and for up to an hour afterwards.

Likelihood Possible Evidence B
Lithium

Theoretically, abrupt coffee withdrawal might increase the levels and adverse effects of lithium.
Coffee contains caffeine. Abrupt caffeine withdrawal can increase serum lithium levels. Two cases of lithium tremor that worsened with abrupt coffee withdrawal have been reported. There is also one case of a 2.8-fold increase in blood lithium levels after a patient taking lithium reduced his coffee consumption from 13-20 cups daily to 10 cups daily.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Coffee contains caffeine. Caffeine has been shown to inhibit monoamine oxidase (MAO) A and B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.

Likelihood Possible Evidence D
Nicotine

Theoretically, concomitant use might increase the risk of hypertension.
Coffee contains caffeine. Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.

Likelihood Probable Evidence B
Pentobarbital (Nembutal)

Theoretically, coffee might reduce the effects of pentobarbital.
Coffee contains caffeine. Theoretically, caffeine might negate the hypnotic effects of pentobarbital.

Likelihood Possible Evidence B
Phenylpropanolamine

Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Coffee contains caffeine. Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.

Likelihood Probable Evidence B
Pioglitazone (Actos)

Theoretically, coffee might increase the levels and clinical effects of pioglitazone.
Coffee contains caffeine. Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Coffee contains caffeine. Concomitant use of caffeine and quinolones can decrease caffeine clearance and increase effects and risk of adverse effects.

Likelihood Probable Evidence B
Riluzole (Rilutek)

Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Coffee contains caffeine. Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce metabolism of one or both agents.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, concomitant use might increase stimulant adverse effects.
Coffee contains caffeine. Due to the central nervous system (CNS) stimulant effects of caffeine, concomitant use with stimulant drugs can increase the risk of adverse effects.

Likelihood Probable Evidence C
Theophylline

Theoretically, coffee might increase the levels and adverse effects of theophylline.
Coffee contains caffeine, which can increase theophylline levels.

Likelihood Probable Evidence B
Green Coffee bean extract full monograph & all 33 interactions

Raspberry Ketone2 drug types · 174 drugs

Stimulant Drugs

Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Heart palpitations, elevated blood pressure, coronary vasospasm, pulseless electrical activity arrest, and resistant polymorphic ventricular tachycardia have been reported in patients taking raspberry ketone.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, raspberry ketone might increase warfarin dose requirements.
In one case report, a patient taking warfarin 55 mg per week had a decrease in INR over a period of one month while taking raspberry ketone 250 mg daily. A warfarin dose increase to 70 mg per week was necessary to maintain a therapeutic INR while taking raspberry ketone. The mechanism for this potential interaction is not known.

Likelihood Possible Evidence D
Raspberry Ketone full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Raspberry Keytones+, from the product label.

Purely Inspired

See all Purely Inspired products
Web Address
www.purelyinspired.com
Pharmacist Counseling Corner

Raspberry Keytones+ by Purely Inspired: Common Questions

Does Raspberry Keytones+ by Purely Inspired interact with any medications?
Yes. Based on its ingredients, Raspberry Keytones+ has a known interaction with 591 medications, including 8 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Raspberry Keytones+ contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product help with weight loss?
Raspberry ketone is one of the active ingredients here, but we don't have enough reliable evidence to say whether it works for obesity. The evidence just isn't established yet in our data.
Will this make me jittery or keep me awake?
The green coffee bean extract contains caffeine, which can cause agitation, anxiety, insomnia, and nervousness—especially at higher doses or if you're sensitive to caffeine. These effects are more likely in children and older adults. If you're caffeine-sensitive, this may not be the right pick for you.
Can I take this if I'm pregnant?
Raspberry ketone has insufficient safety information, so it's best to avoid it. Green coffee bean extract is possibly safe, but you should discuss safe caffeine limits with your doctor before taking anything. The decision needs to be personal to your situation.
Is the green coffee bean extract the same thing as regular coffee?
Green coffee bean extract comes from unroasted coffee beans and contains caffeine, just like regular coffee does. But supplement doses can be more concentrated, and high-dose caffeine carries more risk of side effects than a cup of coffee typically would.
What are the inactive ingredients, and do they matter?
The product contains microcrystalline cellulose, dicalcium phosphate dihydrate, hydroxypropylcellulose, magnesium stearate, stearic acid, croscarmellose sodium, silicon dioxide, and a vegetable-based coating—these are fillers, binders, and capsule materials. For most people they're not a concern, but if you have an allergy to any of them or specific dietary restrictions, check the full list.
Can I take this while breastfeeding?
Raspberry ketone has insufficient safety information—avoid it while nursing. Green coffee bean extract is possibly safe, but the caffeine passes into breast milk, so keep your intake low and watch your baby for fussiness or poor sleep. Talk with your doctor or pharmacist about what's safe for you and your baby.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Raspberry Keytones+ label
Go deeper

The Full Monographs Behind Raspberry Keytones+’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Raspberry Ketone

Interacts with 174 drugs

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence that it helps people lose weight. Most cla...

Read the full Raspberry Ketone monograph → Herb & supplement monograph

Coffee

Interacts with 591 drugs

Coffee is a widely consumed beverage made from roasted coffee beans, valued mainly for its caffeine, which boosts alertness and energy. For most healthy adults, moderate coffee intake is gen...

Read the full Coffee monograph →
Sources

Sources & How We Checked

Raspberry Keytones+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 179 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Raspberry Ketone 4 references
  1. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
  2. Adverse Event Report. Raspberry Ketone. Natural MedWatch, September 18, 2011.
  3. Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
  4. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.

See these in context on the Raspberry Ketone monograph →

Coffee 175 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Harder S, Fuhr U, Staib AH, Wolff T. Ciprofloxacin-caffeine: a drug interaction established using in vivo and in vitro investigations. Am J Med 1989;87:89S-91S. PubMed
  3. Carbo M, Segura J, De la Torre R, et al. Effect of quinolones on caffeine disposition. Clin Pharmacol Ther 1989;45:234-40. PubMed
  4. Healy DP, Polk RE, Kanawati L, et al. Interaction between oral ciprofloxacin and caffeine in normal volunteers. Antimicrob Agents Chemother 1989;33:474-8. PubMed
  5. Mester R, Toren P, Mizrachi I, et al. Caffeine withdrawal increases lithium blood levels. Biol Psychiatry 1995;37:348-50. PubMed
  6. Jefferson JW. Lithium tremor and caffeine intake: two cases of drinking less and shaking more. J Clin Psychiatry 1988;49:72-3.
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See these in context on the Coffee monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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