SAMe 200 By Klaire Labs Overview & Drug Interactions
Check For Interactions With SAMe 200
Supplement: SAMe 200 by Klaire Labs
SAMe 200 Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
S-Adenosyl L-Methionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
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S-Adenosyl L-Methionine Tosylate Disulfate
Description:S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same
Ingredient Group SAMe Category non-nutrient/non-botanical
Drugs that interact with SAMe 200 by Klaire Labs
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| Servings per container | 60 |
| UPC/BARCODE | 828054010215 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| S-Adenosyl L-Methionine |
200 mg
|
SAMe |
--
|
| S-Adenosyl L-Methionine Tosylate Disulfate |
400 mg
|
SAMe |
|
| Other Ingredients: |
Microcrystalline Cellulose
Magnesium Silicate
Food Glaze
Magnesium Stearate
Stearic Acid
Magnesium Hydroxide
Glycerol
Silicon Dioxide
Arginine
Sodium Alginate
Calcium Oxide
|
|---|
Label Statments:
| Formula |
- 200 mg Elemental SAMe s-adenosyl l-methionine
- Each tablet contains a full 200 mg of elemental SAMe from 400 mg SAMe tosylate disulfate.
- SAMe (S-adenosylmethionine) is a derivative of the essential amino acid methionine and is formed by combining ATP with L-methionine. SAMe is a chiral molecule and consists of two stereoisomers: (S,S) and (R,S). This SAMe has a high level (65%) of the (S,S) isomer, the biologically active form.
|
|---|---|
| FDA Statement of Identity |
- Dietary Supplement
|
| Formulation |
- 60 enteric extended release tablets in foil blister packets
- This SAMe 200 is a pharmaceutical grade, stabilized SAMe manufactured under low temperature and low humidity conditions.
- These enteric extended release tablets offer improved delivery and comply with or exceed the standards established by the United States Pharmacopeia (USP). Slow-release coating technology optimizes stability in the stomach and enhances direct release and absorption in the small intestine.
- SAMe has a long history of clinical use with proven benefits for brain metabolism, joint function, and liver detoxification. Some of the reported beneficial actions of SAMe include:
Joint and connective tissue strength
SAMe supports production of healthy connective tissue and joint structures by contributing its sulfur component for transulfuration processes that help form glucosamine and chondroitin sulfates, critical components of connective tissues.
Brain metabolism
SAMe serves as a major source of methyl groups used by the brain in the synthesis of neurotransmitters such as serotonin, L-dopa, dopamine, and related hormones involved in mood regulation.
Liver function
Metabolism of SAMe supports synthesis of glutathione and glutathione-dependant enzymes (glutathione peroxidase and glutathione-S-transferase), which are important antioxidants used in liver detoxification processes.
- Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans.
- SAMe 200 is provided in individual foil blister packets to maximize product stability.
- Produced in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.
|
| Brand IP Statement(s) |
- SFI
|
| Precautions |
- Caution: If under 18 years of age, pregnant/nursing, have a medical condition or taking a prescription medication - including those related to mood modulation - consult your physician before use.
- Do not exceed 1,600 mg SAMe per day (8 tablets). Do not take at night since product may cause anxiety, restlessness and insomnia.
- Caution: If under 18 years of age, pregnant/nursing, have a medical condition or taking a prescription medication - including those related to mood modulation - consult your physician before use.
Keep out of reach of children.
- Do not use if outer seal of blister pack is broken.
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|
| Suggested/Recommended/Usage/Directions |
- Suggested use: Adults: 1 tablet, 2 to 6 times daily or as directed by a healthcare professional. Do not chew or crush tablets.
|
| Storage |
- Store in a cool, dry place (59 degrees F-85 degrees F) away from direct light.
|
Brand Information
See all products by this brand
| Manufactured for: | |
|---|---|
| Name | SFI USA |
| City | Reno |
| State | NV |
| ZipCode | 89521 |
| Web Address | Klaire.com |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.