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Dietary supplement

Stevia Ingredients & Drug Interactions

by plnt

Stevia label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Stevia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Stevia is a dietary supplement by plnt with 1 active ingredient. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Stevia by plnt

Ask about any prescription or over-the-counter medication and we check it for interactions with Stevia by plnt — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Stevia by plnt

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Stevia by plnt is a liquid extract made from stevia leaf. It contains one active ingredient: stevia leaf extract, a sweetener derived from the stevia plant.

The liquid also includes vegetable glycerin and deionized water as inactive ingredients to keep it in liquid form.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Stevia product and its label doesn't state a use — see Stevia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold rates stevia's effectiveness for diabetes, high blood pressure, and obesity as insufficient — there simply isn't enough reliable clinical evidence yet to say whether it works for those purposes. While some early research hints that stevia might affect blood sugar and blood pressure, the findings are too limited or mixed for us to make a solid claim.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Purified stevia used in typical food amounts is generally recognized as safe. However, because this is a supplement in concentrated liquid form rather than a food additive, the safety data is thinner.

The data advises caution with high-dose supplements, since they haven't been studied as thoroughly. When taken orally, stevia is generally well tolerated, and most mild side effects — like bloating, dizziness, headache, muscle aches, nausea, and numbness — tend to go away after the first week.

Allergic reactions are rare but possible.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using stevia if you take lithium — stevia might theoretically raise lithium levels to unsafe ranges (Moderate severity). Also ask about blood pressure medications (antihypertensive drugs) and diabetes medications, as stevia could theoretically increase the risk of low blood pressure or low blood sugar (Minor severity for both).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Stevia is a popular plant-based sweetener that's generally well tolerated in food amounts, though concentrated supplement doses haven't been studied as much. If you take lithium, blood pressure medication, or diabetes medication, you'll want to check with your doctor or pharmacist before adding this product — the interactions, while mostly theoretical, are real enough to warrant a conversation.

Anyone else can likely use it, but if you're pregnant, nursing, or have questions about your own medications, talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stevia, straight from the product label.

Brand plnt
Barcode (UPC) 766536024926
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 208767
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stevia by plnt, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7 Drop(s)
Maximum serving Sizes:
7 Drop(s)
Servings per container
295
UPC/BARCODE
766536024926
IngredientAmount% DV
Stevia Leaf Extract50 mg--

Other ingredients: Vegetable Glycerin, deionized Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Pure living, naturally true

Naturally flavored

Formulation

Non-GMO Zero calories

Gluten free Dairy free Nut free Soy free Does not contain: Gluten, sugar, salt, animal derivatives, preservatives, artificial colors or flavors.

Seals/Symbols

Non GMO Project Verified nongmoproject.org

K Parve K-1604

Quality promise Tested & trusted

FDA Statement of Identity

Liquid Dietary Supplement

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken.

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Formula

K Parve K-1604

Suggested/Recommended/Usage/Directions

Directions: Add up to 7 drops to beverages or food. Adjust as needed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Stevia by plnt label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Stevia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Stevia by plnt

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size7 Drop(s) Dosage formLiquid Servings per container295 Amounts shown are per serving.

Stevia Leaf Extract

Interacts with
259 drugs
50 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia Leaf Extract monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Deionized Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stevia by plnt Drug Interactions

Want to check YOUR meds against Stevia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Stevia Leaf Extract 259

Individual Drug Interactions

The ingredients in Stevia interact with 259 drugs. Click any drug to see the details.

1 of the 1 ingredient in Stevia interact with drugs. Each result below shows which ingredient is responsible. Stevia Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Stevia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia Leaf Extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Stevia, from the product label.

plnt

See all plnt products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-866-293-3367
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Stevia by plnt: Common Questions

Does Stevia by plnt interact with any medications?
Yes. Based on its ingredients, Stevia has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stevia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the side effects?
Most people tolerate stevia well. The most common mild effects — bloating, dizziness, headache, muscle aches, nausea, and numbness — usually fade after your first week of use. Allergic reactions are rare. If any symptom lingers or bothers you, mention it to your pharmacist.
Does stevia actually help with blood sugar or weight loss?
The evidence we hold isn't conclusive enough to say. Early research hints stevia might affect blood sugar after meals, but we don't have reliable proof that it helps with diabetes or weight loss yet.
Is this safe to use in pregnancy?
We don't have enough data on this product to know. Talk with your doctor or pharmacist before taking stevia while pregnant or breastfeeding — they can give you personalized advice based on your situation.
What makes this different from stevia in packets or food?
This is a concentrated supplement liquid rather than a small food additive. Purified stevia in typical food amounts is recognized as safe, but high-dose supplements like this haven't been studied as thoroughly, so caution is advised.
Can I use this as a sweetener every day?
In food amounts, stevia is generally recognized as safe for regular use. This liquid version is more concentrated, so if you're using it daily as a sweetener in large amounts, it's worth confirming with your pharmacist that it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stevia label
Go deeper

The Full Monographs Behind Stevia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Stevia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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