Cyclophosphamide

Name: Cyclophosphamide Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

88 interactions 1,015 cited references

Also sold as: Cytoxan® Frindovyx

About Cyclophosphamide

Cyclophosphamide is used alone or in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection); cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that fir… Read the full Cyclophosphamide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Varicella Virus Vaccine, Live Yellow Fever Vaccine Mumps Virus Vaccine, Live Measles Virus Vaccine, Live Dengue Tetravalent Vaccine, Live Bacillus Of Calmette And Guerin Vaccine, Live

9 Contraindicated 47 Major 31 Moderate 1 Minor

All (88) Contraindicated (9) Major (47) Moderate (31) Minor (1)

Minor

Cyclophosphamide Indomethacin Indocin Fluid retention Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.