Drug & supplement interaction

Betony + Insulin Degludec

Insulin Degludec brand name: Tresiba.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Betony and Insulin Degludec in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Betony and Insulin Degludec

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Insulin Degludec and Betony in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Betony safety at a glance

Betony overall Use caution Generally used in traditional teas, but human safety data are limited, so use with care.
Pregnancy Avoid Traditionally avoided in pregnancy because of possible effects on the uterus; safety is not established.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Insulin Degludec and Betony? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Insulin Degludec

Interactions in our licensed database are recorded against drug classes, not just single drug names. Insulin Degludec is filed under a single classification — antidiabetes drugs. Betony has documented interactions with 1 drug class — the most serious being antihypertensive drugs (moderate) — and none of Insulin Degludec’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Betony Does Interact With Other Medications

Betony has 172 moderate known drug interactions in our database — Insulin Degludec isn’t one of them. If you take anything else, check it against the full list below.

Moderate 172 No known interaction 2,658 (incl. Insulin Degludec)
Taking anything else?

Check Another of Your Medications Against Betony

Covers the 2,830 medications we’ve checked against Betony. Pick one to open its full report.

What to actually watch for

What Insulin Degludec’s Own FDA Label Lists

This is not an interaction — none of it involves Betony. These are the most notable effects listed in the ADVERSE REACTIONS section of Insulin Degludec’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • High blood sugar Worth acting on mentioned in 15.8% of FDA reports for Insulin Degludec
  • Low blood sugar Worth acting on mentioned in 9.4% of FDA reports for Insulin Degludec
  • Low potassium Worth acting on
  • Wheezing Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on

Showing the 10 most notable of 20 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Insulin Degludec. Read the label on DailyMed › Where a percentage is shown, it is the share of 24,909 voluntary FDA FAERS reports for Insulin Degludec that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Betony’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Betony side to compare — that is a limit of the record, not a statement that Betony has no side effects.

Everything else you take

See Every Supplement That Interacts With Insulin Degludec

This page covers Betony only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Insulin Degludec page lists 239 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate), Agaricus Mushroom (moderate) and Agmatine (moderate).

By severity: 1 major · 208 moderate · 30 minor.

From our pharmacist’s overview on the Insulin Degludec page

“Insulin degludec (Tresiba) is a long-acting insulin meant to hold blood sugar steady around the clock, which means anything else that pushes glucose down can push it too far. That is the story for nearly all 239 ingredients on this page, and the list warrants genuine caution.”

Reviewed by 2 · Jul 18, 2026

Open the Insulin Degludec interaction page

One more smart check

Taking Betony as Part of a Dietary Supplement Product? Check It for Interactions

We hold 188 real supplement products containing Betony, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Betony. Even though Betony itself has no known interaction with Insulin Degludec, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Betony and Insulin Degludec Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Betony
Top half

#438 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Insulin Degludec
Top half

#1,020 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Betony reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Betony and Insulin Degludec records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Betony

What is Betony?

  • Headaches and tension
  • Anxiety and nervous tension
  • Digestive upset
  • Sore throat and mouth rinse
  • Mild diarrhea

Betony (Stachys officinalis) is a traditional European herb long used for headaches, nervous tension, and digestive complaints. Modern scientific evidence supporting these uses is very limited, and most claims rest on tradition rather than well-designed human studies. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Stachys officinalis · Lamiaceae · Aerial parts (leaves, stems, and flowers) · Tea, tincture, dried herb, capsules

An interaction check asks whether these two react with each other — it does not ask whether Betony is a good idea for someone in your situation. Here is what our Betony record says about it on its own.

Betony: dosing

There is no standardized or officially established dose for betony. Traditional use typically involved a tea made from a small amount of the dried herb, but reliable dosing information from clinical studies is not available.If you decide to use a betony product, follow the directions on the product label and do not exceed the recommended amount.

From our Betony monograph — the full record covers uses, side effects and every documented interaction.

Read the full Betony monograph & all interactions
Medication

About Insulin Degludec (rDNA Origin) Injection

What Is Insulin Degludec (rDNA Origin) Injection Used For?

Brand name: Tresiba

Insulin degludec (brands: Insulin Degludec, Tresiba) is indicated to improve glycemic control (blood sugar management) in patients 1 year of age and older with diabetes mellitus — both type 1 and type 2.

It is not recommended for treating diabetic ketoacidosis (a dangerous complication where acids build up in the blood). In patients with type 1 diabetes, it must be used together with a short-acting insulin.

Most-Reported Side Effects for Insulin Degludec

From FAERS, the FDA’s public side-effect reporting system (24,909 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Blood glucose increased 3,929 reports
Nausea 1,601 reports
Blood glucose decreased 1,336 reports
Vomiting 1,069 reports
Diarrhea 1,038 reports
See full Insulin Degludec (rDNA Origin) Injection drug information
Keep checking

Other Drugs & Betony

Browse every other medication we’ve checked against Betony — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
172Moderate
0Minor
2,657No known interaction
172 Moderate 2,657 No interaction
Moderate

172 interactions

Showing 60 of 172 moderate interactions — see all 172 on the Betony page.

No interaction 2,657 drugs checked — show the list

We also checked Betony against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,657 medications checked with no known interaction — see the full Betony list.

See the full Betony interactions page
See every supplement checked against Insulin Degludec, ranked by severity
Evidence & sources

Betony References

The 2 references that drive our Betony monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Betony and Insulin Degludec Together: Common Questions

Is it safe to take Betony with Insulin Degludec?
We do not list a known interaction between Betony and Insulin Degludec. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Betony and Insulin Degludec combination checked?
Interactions in our licensed database are recorded against drug classes. Insulin Degludec is filed under 1 classification, and Betony has documented interactions with 1 drug class — none of Insulin Degludec's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Betony interact with any other medications?
Yes. Betony has 172 documented drug interactions in our database — Insulin Degludec is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Insulin Degludec interact with any supplements?
Yes. Insulin Degludec has documented interactions with 239 supplements in our database — Betony is not one of them. The Insulin Degludec interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Betony monograph Uses, safety profile, and every drug interaction in one place Insulin Degludec (rDNA Origin) Injection drug information The full plain-English guide to this medication Insulin Degludec supplement interactions Every supplement checked against Insulin Degludec, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Insulin Degludec and Betony?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.