Drug & supplement interaction

Brussels Sprout + Levetiracetam

Levetiracetam brand names: Keppra, Elepsia XR, Spritam.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Brussels Sprout and Levetiracetam in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Brussels Sprout and Levetiracetam

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Levetiracetam and Brussels Sprout in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Brussels Sprout safety at a glance

Brussels Sprout overall Generally safe Generally safe and healthy when eaten as a normal food.
Pregnancy Generally safe Safe to eat in normal food amounts during pregnancy; concentrated supplements are not well studied.
Breastfeeding Generally safe Safe as a food while breastfeeding; concentrated extracts have not been studied.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Levetiracetam and Brussels Sprout? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Levetiracetam

Interactions in our licensed database are recorded against drug classes, not just single drug names. Levetiracetam is filed under 3 classifications — anticonvulsants, cns depressants, oral drugs. Brussels Sprout has documented interactions with 5 drug classes — the most serious being acetaminophen (tylenol, others) (moderate), cytochrome p450 1a2 (cyp1a2) substrates (moderate) and glucuronidated drugs (moderate) — and none of Levetiracetam’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Brussels Sprout Does Interact With Other Medications

Brussels Sprout has 241 moderate known drug interactions in our database — Levetiracetam isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Brussels Sprout

Covers the 2,830 medications we’ve checked against Brussels Sprout. Pick one to open its full report.

What to actually watch for

What Brussels Sprout Itself Has Been Linked To

This is not an interaction — nothing below involves Levetiracetam. It is the side-effect record for Brussels Sprout on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Brussels Sprout, this list is the first place to look.

  • Bloating or gas Additional detail

    “Orally, Brussels sprout is generally well-tolerated when consumed in dietary amounts. Eating Brussels sprout or other types of fermentable carbohydrates can cause flatulence.”

    Brussels Sprout · Natural Medicines adverse-effect record, reported in flatulence.

    1 source cited
    1. 26470. Allaby RG, Peterson GW, Merriwether DA, Fu YB. Evidence of the domestication history of flax (Linum usitatissimum L.) from genetic diversity of the sad2 locus. Theor Appl Genet. 2005 Dec;112(1):58-65. PubMed

    “Orally, eating Brussels sprout or other types of fermentable carbohydrates can cause flatulence.”

    Brussels Sprout · Natural Medicines adverse-effect record, reported in flatulence.

    1 source cited
    1. 26470. Allaby RG, Peterson GW, Merriwether DA, Fu YB. Evidence of the domestication history of flax (Linum usitatissimum L.) from genetic diversity of the sad2 locus. Theor Appl Genet. 2005 Dec;112(1):58-65. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Brussels Sprout — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Levetiracetam’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Levetiracetam column appears here.

From our Q&A

Questions About Brussels Sprout or Levetiracetam

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Brussels Sprout or Levetiracetam, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Levetiracetam

This page covers Brussels Sprout only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Levetiracetam page lists 105 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 82 moderate · 16 minor.

From our pharmacist’s overview on the Levetiracetam page

“I would read this page carefully rather than casually. Levetiracetam (Keppra, Spritam) controls seizures, and both hazards on this list run through that fact.”

Reviewed by 2 · Jul 18, 2026

Open the Levetiracetam interaction page

How much people look this up

Where Brussels Sprout and Levetiracetam Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Brussels Sprout
Steady interest

#1,194 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Levetiracetam
Top 5%

#95 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Brussels Sprout reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Brussels Sprout and Levetiracetam records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Brussels Sprout

What is Brussels Sprout?

  • General nutrition and fiber
  • Antioxidant support
  • Digestive health
  • Heart health support
  • Cancer-prevention interest

Brussels sprouts are a nutritious cruciferous vegetable rich in fiber, vitamin C, vitamin K, and plant compounds called glucosinolates. Eating them as part of a balanced diet is healthy and safe for most people, but supplement-style claims (like preventing cancer) are not well proven. If you take blood thinners or have thyroid concerns, talk with your pharmacist or doctor about your intake.

Brassica oleracea var. gemmifera · Brassicaceae · Edible sprouts (small leafy buds) · Fresh or cooked vegetable, frozen, powdered, capsule or extract supplements

An interaction check asks whether these two react with each other — it does not ask whether Brussels Sprout is a good idea for someone in your situation. Here is what our Brussels Sprout record says about it on its own.

Brussels Sprout: dosing

There is no official "dose" for Brussels sprouts because they are a food, not a drug. A normal serving as part of meals is appropriate for most people, and they can be enjoyed several times a week as part of a vegetable-rich diet.If you choose a Brussels sprout or cruciferous vegetable supplement, there is no standardized, proven dose.

From our Brussels Sprout monograph — the full record covers uses, side effects and every documented interaction.

Read the full Brussels Sprout monograph & all interactions
Medication

About Levetiracetam

What Is Levetiracetam Used For?

Brand names: Keppra, Elepsia XR, Spritam

Levetiracetam is used to treat several types of seizures. It treats partial-onset seizures (seizures that start in one area of the brain) and is used as add-on therapy for myoclonic seizures (sudden, brief muscle jerks) in people with juvenile myoclonic epilepsy aged 12 and older, and for primary generalized tonic-clonic seizures (grand mal seizures) in people with idiopathic generalized epilepsy aged 6 and older.

Age eligibility varies by product. Keppra oral and Roweepra tablets treat partial-onset seizures in patients as young as 1 month. Spritam and levetiracetam tablets for oral suspension treat partial-onset seizures in patients 4 years and older weighing more than 20 kg. Extended-release products — including Elepsia XR, Keppra XR, and Levetiracetam ER — are approved only for partial-onset seizures in patients 12 years and older. Injectable forms are used intravenously when a patient temporarily cannot take oral medication.

Most-Reported Side Effects for Levetiracetam

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Seizure 15,978 reports
Fatigue 5,591 reports
Somnolence 4,177 reports
Epilepsy 4,136 reports
Convulsion 4,085 reports
See full Levetiracetam drug information
Keep checking

Other Drugs & Brussels Sprout

Browse every other medication we’ve checked against Brussels Sprout — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
241Moderate
0Minor
2,588No known interaction
Moderate

241 interactions

Showing 60 of 241 moderate interactions — see all 241 on the Brussels Sprout page.

No interaction 2,588 drugs checked — show the list
Evidence & sources

Brussels Sprout References

The 19 references that drive our Brussels Sprout monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pantuck EJ, Pantuck CB, Anderson KE, et al. Effect of brussels sprouts and cabbage on drug conjugation. Clin Pharmacol Ther 1984;35:161-9. PubMed
  2. Joshipura KJ, Ascherio A, Manson JE, et al. Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA 1999;282:1233-39. PubMed
  3. Zhao H, Lin J, Grossman HB, et al. Dietary isothiocyanates, GSTM1, GSTT1, NAT2 polymorphisms and bladder cancer risk. Int J Cancer 2007;120:2208-13.
  4. Cohen, J. H., Kristal, A. R., and Stanford, J. L. Fruit and vegetable intakes and prostate cancer risk. J Natl.Cancer Inst. 1-5-2000;92(1):61-68. PubMed
  5. Kolonel, L. N., Hankin, J. H., Whittemore, A. S., Wu, A. H., Gallagher, R. P., Wilkens, L. R., John, E. M., Howe, G. R., Dreon, D. M., West, D. W., and Paffenbarger, R. S., Jr. Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control st
  6. Kissel JT, Scott CB, Reyna SP, Crawford TO, Simard LR, Krosschell KJ, Acsadi G, Elsheik B, Schroth MK, D'Anjou G, LaSalle B, Prior TW, Sorenson S, Maczulski JA, Bromberg MB, Chan GM, Swoboda KJ; Project Cure Spinal Muscular Atrophy Investigators' Network.
  7. Ovesen L, Lyduch S, Idorn ML. The effect of a diet rich in Brussels sprouts on warfarin pharmacokinetics. Eur J Clin Pharmacol 1998;34(5):521-523. PubMed
  8. Wortelboer HM, de Kruif CA, van Iersel AAJ, et al. Effects of cooked Brussels sprouts on cytochrome P-450 profile and phase II enzymes in liver and small intestinal mucosa of the rat. Food Chem Toxicol 1992;30(1):17-27. PubMed
  9. Michaud DS, Spiegelman D, Clinton SK, et al. Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. J Natl Cancer Inst 1999;91(7):605-13. PubMed
  10. Chang ET, Smedby KE, Zhang SM, et al. Dietary factors and risk of non-Hodgkin lymphoma in men and women. Cancer Epidemiol Biomarkers Prev 2005;14(2):512-20. PubMed
  11. Liu S, Serdula M, Janket SJ, et al. A prospective study of fruit and vegetable intake and the risk of type 2 diabetes in women. Diabetes Care 2004;27(12):2993-6. PubMed
  12. Gaudet MM, Britton JA, Kabat GC, et al. Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status. Cancer Epidemiol Biomarkers Prev 2004;13(9):1485-94. DOI
  13. Smith-Warner SA, Spiegelman D, Yaun SS, et al. Intake of fruits and vegetables and risk of breast cancer: a pooled analysis of cohort studies. JAMA 2001;285(6):769-76.
  14. Rohrmann S, Giovannucci E, Willett WC, Platz EA. Fruit and vegetable consumption, intake of micronutrients, and benign prostatic hyperplasia in US men. Am J Clin Nutr 2007;85(2):523-9. PubMed
  15. Brennan P, Hsu CC, Moullan N, et al. Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach. Lancet 2005;366(9496):1558-60. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Brussels Sprout and Levetiracetam Together: Common Questions

Is it safe to take Brussels Sprout with Levetiracetam?
We do not list a known interaction between Brussels Sprout and Levetiracetam. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Brussels Sprout and Levetiracetam combination checked?
Interactions in our licensed database are recorded against drug classes. Levetiracetam is filed under 3 classifications, and Brussels Sprout has documented interactions with 5 drug classes — none of Levetiracetam's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Brussels Sprout interact with any other medications?
Yes. Brussels Sprout has 241 documented drug interactions in our database — Levetiracetam is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Levetiracetam interact with any supplements?
Yes. Levetiracetam has documented interactions with 105 supplements in our database — Brussels Sprout is not one of them. The Levetiracetam interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.