Drug & supplement interaction

Damiana + Diclofenac Sodium

Diclofenac Sodium brand names: Voltaren XR, Voltaren, Voltaren SR, Diclo, Difenac, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Damiana and Diclofenac Sodium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Damiana and Diclofenac Sodium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Diclofenac Sodium and Damiana in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Damiana safety at a glance

Damiana overall Use caution Likely fine in food/tea amounts for most adults, but human safety data are limited.
Pregnancy Avoid Not enough safety data; avoid during pregnancy.
Breastfeeding Avoid Not enough safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Diclofenac Sodium and Damiana? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Diclofenac Sodium

Interactions in our licensed database are recorded against drug classes, not just single drug names. Diclofenac Sodium is filed under 11 classifications — including nonsteroidal anti-inflammatory drugs (nsaids), cytochrome p450 2c9 (cyp2c9) substrates, anticoagulant/antiplatelet drugs. Damiana has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Diclofenac Sodium’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Damiana Does Interact With Other Medications

Damiana has 86 moderate known drug interactions in our database — Diclofenac Sodium isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Diclofenac Sodium)
Taking anything else?

Check Another of Your Medications Against Damiana

Covers the 2,830 medications we’ve checked against Damiana. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Damiana and Diclofenac Sodium May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Seizures Worth acting on Additional detail

    Damiana

    “Orally, 200 grams of damiana extract has caused tetanus-like convulsions and paroxysms resulting in symptoms similar to rabies or strychnine poisoning (4).”

    Damiana · Natural Medicines adverse-effect record, reported in poisoning.

    1 source cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

    Diclofenac Sodium

    Listed in the ADVERSE REACTIONS section of the FDA label for Diclofenac Sodium. Read the label on DailyMed ›

Effects for Diclofenac Sodium come from the ADVERSE REACTIONS section of its FDA label; effects for Damiana come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 155,962 voluntary FDA FAERS reports for Diclofenac Sodium that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Damiana or Diclofenac Sodium

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Damiana or Diclofenac Sodium, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Diclofenac Sodium

This page covers Damiana only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Diclofenac Sodium page lists 308 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Danshen (major) and Piracetam (major).

By severity: 7 major · 266 moderate · 35 minor.

From our pharmacist’s overview on the Diclofenac Sodium page

“Diclofenac (Voltaren), a daily mainstay for arthritis and joint pain, comes with a supplement list that calls for real vigilance. Of the 308 ingredients on file, 7 rate major, and roughly two hundred entries share a single theme: anything with blood-thinning activity adds to diclofenac's own bleeding risk, especially in the stomach.”

Reviewed by 2 · Jul 18, 2026

Open the Diclofenac Sodium interaction page

One more smart check

Taking Damiana as Part of a Dietary Supplement Product? Check It for Interactions

We hold 881 real supplement products containing Damiana, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Damiana. Even though Damiana itself has no known interaction with Diclofenac Sodium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Damiana and Diclofenac Sodium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Damiana
Top 25%

#187 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Diclofenac Sodium
Top 10%

#240 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Damiana reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Damiana and Diclofenac Sodium records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Damiana

What is Damiana?

Damiana
  • Low libido / aphrodisiac
  • Anxiety and stress
  • Mood and mild low energy
  • Digestive upset
  • Headache and general tonic

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small amounts found in teas, but quality studies are lacking, so talk with your pharmacist or doctor before using it—especially if you are pregnant, breastfeeding, or have a health condition.

Turnera diffusa · Passifloraceae · Leaves (and sometimes stems) · Tea, capsules, tinctures, liquid extracts, dried leaf

An interaction check asks whether these two react with each other — it does not ask whether Damiana is a good idea for someone in your situation. Here is what our Damiana record says about it on its own.

Damiana: dosing

There is no well-established standard dose for damiana. The amount people use varies widely depending on the form—tea, capsule, or tincture.The safest approach is to follow the directions on the product label and not exceed the recommended amount. Because strength differs from product to product, a pharmacist can help you decide whether a particular product and dose make sense for you.If you try damiana, start low, watch how you feel, and stop if you notice side effects.

From our Damiana monograph — the full record covers uses, side effects and every documented interaction.

Read the full Damiana monograph & all interactions
Medication

About Diclofenac

What Is Diclofenac Used For?

Brand names: Voltaren XR, Voltaren, Voltaren SR, Diclo, Difenac, Diclo SR, Voltarol, Acoflam, Defenac, Dicloflex, Diclovol, Diclozip, Fenactol, Flamrase, Volraman, Diclomax SR, Diclomax Retard, Motifene 75 mg, Voltarol 75 mg SR, Acoflam 75 SR, Defenac SR, Dexomon 75 SR, Dicloflex 75 SR, Diclovol SR, Fenactol 75 mg SR, Flamatak 75 MR, Flamrase SR, Flexotard MR 75, Rheumatac Retard 75, Rhumalgan CR, Slofenac SR, Volsaid Retard 75, Voltarol Retard, Acoflam Retard, Defenac Retard, Dexomon Retard 100, Dicloflex Retard, Diclovol Retard, Fenactol Retard 100 mg, Flamatak 100 MR, Volsaid Retard 100, Voltarol Ophtha Multidose, Voltarol Ophtha, Pennsaid, Voltaren Emulgel, Dyloject

Diclofenac sodium topical gel is used to treat actinic keratoses (AK) — rough, scaly skin patches that form after years of sun exposure. These patches are considered precancerous, meaning they can develop into skin cancer if left untreated.

This is a topical gel, meaning it is applied directly to the skin over the affected area rather than taken by mouth. It belongs to the NSAID (nonsteroidal anti-inflammatory drug) family.

Most-Reported Side Effects for Diclofenac Sodium

From FAERS, the FDA’s public side-effect reporting system (155,962 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 13,844 reports
Arthralgia 11,333 reports
Rash 10,855 reports
Rheumatoid arthritis 10,744 reports
Abdominal discomfort 9,636 reports
See full Diclofenac drug information
Keep checking

Other Drugs & Damiana

Browse every other medication we’ve checked against Damiana — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Damiana page.

No interaction 2,743 drugs checked — show the list

We also checked Damiana against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Damiana list.

See the full Damiana interactions page
See every supplement checked against Diclofenac Sodium, ranked by severity
Evidence & sources

Damiana References

The 2 references that drive our Damiana monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Damiana and Diclofenac Sodium Together: Common Questions

Is it safe to take Damiana with Diclofenac Sodium?
We do not list a known interaction between Damiana and Diclofenac Sodium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Damiana and Diclofenac Sodium have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Damiana and Diclofenac Sodium combination checked?
Interactions in our licensed database are recorded against drug classes. Diclofenac Sodium is filed under 11 classifications, and Damiana has documented interactions with 1 drug class — none of Diclofenac Sodium's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Damiana interact with any other medications?
Yes. Damiana has 86 documented drug interactions in our database — Diclofenac Sodium is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Diclofenac Sodium interact with any supplements?
Yes. Diclofenac Sodium has documented interactions with 308 supplements in our database — Damiana is not one of them. The Diclofenac Sodium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Damiana monograph Uses, safety profile, and every drug interaction in one place Diclofenac drug information The full plain-English guide to this medication Diclofenac Sodium supplement interactions Every supplement checked against Diclofenac Sodium, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Diclofenac Sodium and Damiana?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.