Major interaction on record — check this product against your medications before combining. Based on 3 of 6 ingredients. Check your meds →
Dietary supplement

Anytime Burn V4 Ingredients & Drug Interactions

by Like A Pro Supplements

Anytime Burn V4 label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Anytime Burn V4 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Anytime Burn V4 is a dietary supplement by Like A Pro Supplements with 6 active ingredients. Its ingredients are commonly taken for blood sugar control, high cholesterol, heart and metabolic health.Based on those ingredients, 1,459 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are KSM-66, GlucoVantage. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Anytime Burn V4 by Like A Pro Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Anytime Burn V4 by Like A Pro Supplements — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Anytime Burn V4 by Like A Pro Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement has 6 active ingredients. The main ones are berberine (via GlucoVantage), which shows up in Ayurvedic medicine and may help with cholesterol and blood sugar; ashwagandha extract (KSM-66), an adaptogen used for stress and sleep; and Grains of Paradise (CaloriBurn GP), a spice traditionally used to support metabolism.

It also contains AstraGin, MitoBurn, and InnoSlim, which are ingredient names you'll see on many performance and weight-loss products. The capsules also contain inactive ingredients like rice flour, cellulose, magnesium stearate, and silicon dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: increase metabolism and calorie expenditure.
  • We looked for evidence on: Obesity, Metabolic syndrome, Diabetes, Impaired glucose tolerance (prediabetes), Hypercholesterolemia, Hyperlipidemia — and 4 related terms.
  • The strongest evidence on file: Berberine is rated "Possibly Effective" for Diabetes (Natural Medicines).
  • Also on file: Berberine is rated "Possibly Effective" for Hyperlipidemia.
  • Also on file: Ashwagandha is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Hypercholesterolemia.

Berberine (GlucoVantage) is rated Possibly Effective for high cholesterol (hyperlipidemia), diabetes, high blood pressure (hypertension), PCOS (polycystic ovary syndrome), and H. pylori infection. Ashwagandha (KSM-66) is rated Possibly Effective for insomnia, anxiety, stress, and GAD (generalized anxiety disorder), though evidence for bipolar disorder is insufficient.

We hold no effectiveness data for Grains of Paradise, AstraGin, MitoBurn, or InnoSlim.

The evidence, ingredient by ingredient Berberine Ashwagandha Grains Of Paradise

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Berberine is generally well tolerated when taken by mouth short-term but commonly causes digestive upset — abdominal pain, constipation, diarrhea, gas, nausea, or vomiting. It may also cause dizziness, drowsiness, fatigue, or headache.

Ashwagandha seems well tolerated in healthy adults short-term, though some people report diarrhea, nausea, or vomiting, and rare serious cases of liver damage have been reported. Both berberine and ashwagandha should be avoided during pregnancy — berberine may cross the placenta and be linked to newborn harm, and ashwagandha has traditionally been thought to increase miscarriage risk.

Neither should be used while breastfeeding because they can pass into breast milk. Grains of Paradise is likely safe in food amounts, but medicinal or supplement doses haven't been well studied in pregnancy or breastfeeding.

Side effects, ingredient by ingredient Berberine Ashwagandha Grains Of Paradise

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Ashwagandha, Berberine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,460 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this product if you use cyclosporine (a Major interaction with berberine), blood thinners or antiplatelet drugs, diabetes medications, blood pressure medications, sedating drugs or benzodiazepines, thyroid hormone, immunosuppressants, or any medication processed by liver enzymes CYP3A4, CYP2D6, or CYP2C9. AstraGin, MitoBurn, and InnoSlim could not be checked for interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Anytime Burn V4 may appeal to people looking to support metabolism, blood sugar, and stress management, since berberine and ashwagandha have some research behind them for those goals. But if you take any prescription medications — especially blood thinners, diabetes drugs, blood pressure meds, benzodiazepines, or immunosuppressants — you need to check with your pharmacist or doctor before starting this.

Pregnant or breastfeeding women should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Anytime Burn V4, straight from the product label.

Brand Like A Pro Supplements
Barcode (UPC) 792816751191
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 335648
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Anytime Burn V4 by Like A Pro Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
792816751191
IngredientAmount% DV
AstraGin50 mg--
MitoBurn1500 mg--
GlucoVantage100 mg--
KSM-66600 mg--
CaloriBurn GP50 mg--
InnoSlim250 mg--

Other ingredients: Rice Flour, Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

24/7 Burning day or night

Regulates glucose levels Increase metabolism Calorie expenditure

This product contains no artificial coloring.

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: For use by healthy adults only, not recommended or persons under the age of 18. Keep out of the reach of children.

Do not use if you are pregnant or nursing. Seek advice from a healthcare professional if you have any preexisting medical condition to ensure it is safe to take this product.

Individuals should not consume other caffeinated products in conjunction with this product. In case of accidental overdose contact a poison control center immediately. Avoid alcohol and prescription stimulants while taking this product. Exceeding recommended serving will not improve results and may cause serious adverse health effects. Discontinue use and contact a licensed healthcare professional immediately if you experience an unusually rapid heartbeat, dizziness, severe headache, or shortness of breath.

Allergen warning Produced in a facility that also processed soy, fish, shellfish, milk, peanuts, tree nuts, wheat and eggs.

Suggested/Recommended/Usage/Directions

Suggested use: Training Days: 2 Capsules before exercise/cardio and 2 before bed. May be stacked with Burn Away at a half serving. Do not exceed 4 capsules per day. Off Days: 2 capsules first thing in the Morning, 2 Capsules before bed.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Anytime Burn V4 by Like A Pro Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Anytime Burn V4 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Anytime Burn V4 by Like A Pro Supplements

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

AstraGin

50 mg per serving Form: Astragalus membranaceous, Panax notoginseng

MitoBurn

1500 mg per serving Form: L-Beta-Aminoisobutyric Acid

GlucoVantage

Interacts with
1,160 drugs
100 mg per serving Form: Dihydroberberine

Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research vari...

GlucoVantage monograph & interactions

KSM-66

Interacts with
1,372 drugs
600 mg per serving Form: Ashwagandha

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

KSM-66 monograph & interactions

CaloriBurn GP

No known
interactions
50 mg per serving Form: Aframomum melegueta

Grains of paradise is a West African spice in the ginger family that people use for digestion, as a spice, and more recently in supplements aimed at m...

CaloriBurn GP monograph & interactions

InnoSlim

250 mg per serving Form: Astragalus membranaceous, Powder, Panax notoginseng, Powder

Other (inactive) ingredients: Rice Flour, Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Anytime Burn V4 by Like A Pro Supplements Drug Interactions

Want to check YOUR meds against Anytime Burn V4?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,459Drugs
1 Major 1,405 Moderate 53 Minor

Ingredients driving the most interactions

KSM-66 1,372
GlucoVantage 1,160

Individual Drug Interactions

The ingredients in Anytime Burn V4 interact with 1,459 drugs. Click any drug to see the details.

2 of the 6 ingredients in Anytime Burn V4 interact with drugs. Each result below shows which ingredient is responsible. KSM-66 GlucoVantage

Each ingredient & the kinds of drugs it affects

For each ingredient in Anytime Burn V4 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

KSM-6610 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
KSM-66 full monograph & interactions

GlucoVantage15 drug types · 1,160 drugs

Cyclosporine (Neoral, Sandimmune)

Berberine can increase serum levels of cyclosporine.
Berberine can reduce metabolism and increase serum levels of cyclosporine. Berberine might inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine.

Likelihood Probable Evidence A
Anticoagulant/Antiplatelet Drugs

Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro and in vivo research suggest that berberine can inhibit platelet aggregation. Theoretically, berberine might have additive effects when used with anticoagulant and antiplatelet drugs and increase the risk of bleeding.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that berberine may lower blood glucose levels. Theoretically, berberine might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, berberine might have additive effects with antihypertensive drugs.
Animal research suggests that berberine can have hypotensive effects. Also, a clinical study suggests that taking berberine in combination with amlodipine can lower systolic and diastolic blood pressure when compared with amlodipine alone.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, berberine might increase the sedative effects of CNS depressants.
Animal research suggests that berberine may have sedative effects. Theoretically, use of berberine along with CNS depressants might produce additive therapeutic and adverse effects.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP2C9.
Preliminary clinical research shows that berberine can inhibit CYP2C9. Theoretically, taking berberine with drugs metabolized by CYP2C9 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP2D6.
In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, use of berberine with drugs metabolized by CYP2D6 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
In vitro research and preliminary clinical research show that berberine moderately inhibits CYP3A4. Theoretically, use of berberine with drugs metabolized by CYP3A4 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence A
Dextromethorphan (Robitussin Dm, Others)

Theoretically, berberine may increase serum levels of dextromethorphan.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 2D6 (CYP2D6) activity and reduce the metabolism of dextromethorphan. This may increase the effects and side effects of dextromethorphan.

Likelihood Possible Evidence B
Losartan (Cozaar)

Berberine might reduce the therapeutic effects of losartan by decreasing its conversion to its active form.
Preliminary clinical research suggests that berberine can inhibit cytochrome P450 2C9 (CYP2C9) activity and reduce metabolism of losartan.

Likelihood Possible Evidence B
Metformin (Glucophage)

Theoretically, berberine might increase the therapeutic and adverse effects of metformin.
In vitro and animal studies show that berberine can increase the systemic exposure and half-life of metformin, potentially increasing metformin's effects and side effects. This interaction seems to be most apparent when berberine is administered 2 hours prior to metformin. Taking berberine and metformin at the same time does not appear to increase systemic exposure to metformin.

Likelihood Possible Evidence D
Midazolam (Versed)

Berberine can reduce metabolism of midazolam, which might increase the risk of severe adverse effects.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 3A4 (CYP3A4) activity and reduce metabolism of midazolam.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Berberine might increase the sedative effect of pentobarbital.
Evidence from animal research shows that berberine can prolong pentobarbital-induced sleeping time. Theoretically, combining berberine and pentobarbital might increase the sedative effects of pentobarbital.

Likelihood Possible Evidence D
Tacrolimus (Prograf)

Berberine has been associated with increased blood levels of tacrolimus.
In a 16-year-old patient with idiopathic nephrotic syndrome who was being treated with tacrolimus 6.5 mg twice daily, intake of berberine 200 mg three times daily increased the blood concentration of tacrolimus from 8 to 22 ng/mL. Following a reduction of the tacrolimus dose to 3 mg daily, blood levels of tacrolimus decreased to 12 ng/mL.

Likelihood Possible Evidence D
Acetazolamide

Laboratory studies and initial clinical findings suggest that berberine has the potential to increase acetazolamide concentrations in the body. More research is needed to confirm this interaction.

Likelihood Possible Evidence C
GlucoVantage full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Anytime Burn V4, from the product label.

Like A Pro Supplements

See all Like A Pro Supplements products
Name
Like A Pro Supplements, LLC
Street Address
1829 Underwood Boulevard
City
Delran
State
NJ
ZipCode
08075
Pharmacist Counseling Corner

Anytime Burn V4 by Like A Pro Supplements: Common Questions

Does Anytime Burn V4 by Like A Pro Supplements interact with any medications?
Yes. Based on its ingredients, Anytime Burn V4 has a known interaction with 1,459 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Anytime Burn V4 contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this product work for weight loss or metabolism?
Berberine and Grains of Paradise are marketed for metabolism support, but we hold no effectiveness data for Grains of Paradise. Berberine is rated Possibly Effective for conditions like high cholesterol and diabetes, which may play a role in metabolic health. Your results will depend on diet, exercise, and individual factors. Talk to your healthcare provider about realistic expectations.
What are the most common side effects I might notice?
Berberine commonly causes digestive upset — bloating, gas, diarrhea, constipation, or nausea — and may cause dizziness, drowsiness, or headache. Ashwagandha occasionally causes diarrhea, nausea, or vomiting. These effects are usually mild, but if they're severe or persistent, stop and talk to your pharmacist.
Can I take this if I'm pregnant or breastfeeding?
No. Berberine should be avoided in pregnancy because it may cross the placenta and has been linked to harm in newborns. Ashwagandha is traditionally thought to raise miscarriage risk. Neither should be used while breastfeeding because both can pass into breast milk. Talk with your doctor about safe alternatives if you're planning pregnancy or are nursing.
Does ashwagandha in this product really help with anxiety and sleep?
Ashwagandha (KSM-66) is rated Possibly Effective for anxiety, GAD, stress, and insomnia based on research, so it may help some people. Your individual response depends on dose, duration, and personal factors. If you have ongoing anxiety or sleep issues, talk to your doctor to make sure this supplement fits your overall treatment plan.
What if I'm already taking a medication — should I avoid this product?
Not necessarily 'avoid' — but you absolutely need to check your specific medications first using the interaction tool on this page. Berberine and ashwagandha interact with many drug types, and in some cases the interaction is serious. Your pharmacist can review your list and tell you whether this product is right for you.
Is berberine in this safe to take long-term?
The data we hold is based on short-term use, and the safety notes caution that berberine is generally tolerated short-term but can cause digestive side effects and interacts with many medicines. Long-term safety hasn't been well established. If you're thinking of taking this for weeks or months, discuss a timeline and monitoring plan with your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Anytime Burn V4 label
Go deeper

The Full Monographs Behind Anytime Burn V4’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Berberine

Interacts with 1,160 drugs

Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research varies and it is not a replacement for presc...

Read the full Berberine monograph → Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph → Herb & supplement monograph

Grains Of Paradise

Grains of paradise is a West African spice in the ginger family that people use for digestion, as a spice, and more recently in supplements aimed at metabolism. Early human research suggests...

Read the full Grains Of Paradise monograph →
Sources

Sources & How We Checked

Anytime Burn V4's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 75 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Berberine 41 references
  1. Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
  2. Janbaz KH, Gilani AH. Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. Fitoterapia 2000;71:25-33.. PubMed
  3. Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
  4. Zhang Y, Li X, Zou D, et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab 2008;93:2559-65. PubMed
  5. Huang XS, Yang GF, Pan YC. Effect of berberin hydrochloride on blood concentration of cyclosporine A in cardiac transplanted patients. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28:702-4.
  6. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  7. Chatterjee P, Franklin MR. Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components. Drug Metab Dispos 2003;31:1391-7. PubMed
  8. Marin-Neto, J. A., Maciel, B. C., Secches, A. L., and Gallo, Junior L. Cardiovascular effects of berberine in patients with severe congestive heart failure. Clin.Cardiol. 1988;11(4):253-260. PubMed
  9. Choudhry, V. P., Sabir, M., and Bhide, V. N. Berberine in giardiasis. Indian Pediatr. 1972;9(3):143-146.
  10. Shanbhag, S. M., Kulkarni, H. J., and Gaitonde, B. B. Pharmacological actions of berberine on the central nervous system. Jpn.J Pharmacol 1970;20(4):482-487. PubMed
  11. Wu, J. F. and Liu, T. P. [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. Yao Xue.Xue.Bao. 1995;30(2):98-102.
  12. Peng, W. H., Hsieh, M. T., and Wu, C. R. Effect of long-term administration of berberine on scopolamine-induced amnesia in rats. Jpn J Pharmacol 1997;74(3):261-266. DOI
  13. Sharda DC. Berberine in the treatment of diarrhoea of infancy and childhood. J Indian M A 1970;54(1):22-24.
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Grains Of Paradise 2 references
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Grains Of Paradise monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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