Bladder Up Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Bladder Up against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bladder Up is a dietary supplement by Cardiovascular Research with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bladder Up by Cardiovascular Research
Ask about any prescription or over-the-counter medication and we check it for interactions with Bladder Up by Cardiovascular Research — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bladder Up by Cardiovascular Research
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Bladder Up contains 2 active ingredients: pumpkin seed oil and polyunsaturated fat. Pumpkin seed oil is the primary active component; it's been studied most for enlarged prostate (benign prostatic hyperplasia).
The softgel capsule itself also contains gelatin and glycerin as inactive ingredients to hold and deliver the oil.
Does it work?
Moderate evidence
Pumpkin seed oil is possibly effective for benign prostatic hyperplasia (enlarged prostate), based on the evidence we have. For other conditions this product may be marketed for — androgenic alopecia (male-pattern hair loss), interstitial cystitis (bladder pain), urinary tract infections, and intestinal parasites — the evidence is insufficient to establish whether it works.
We hold no effectiveness data for the polyunsaturated fat ingredient.
How safe is it?
Well-documented data
Pumpkin seed oil is generally well tolerated when taken orally as a supplement. The most common side effects reported in trials are mild abdominal discomfort, diarrhea, nausea, and vomiting.
Very rarely, anaphylaxis (a severe allergic reaction) has been reported. There are also two case reports of hair loss that occurred 1–3 weeks after eating high amounts of bitter pumpkin or squash — a reaction attributed to a compound called cucurbitacin found in wild pumpkins, not the cultivated seed oil used in supplements.
For pregnancy and breastfeeding, we don't hold enough safety data on concentrated pumpkin seed oil supplements to know whether they're safe; the facts note that food-form pumpkin is fine, but concentrated supplements lack adequate study. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
If you take lithium, double-check with your doctor or pharmacist before starting Bladder Up — pumpkin seed oil may raise your lithium levels. We couldn't check one of the active ingredients (polyunsaturated fat) because we hold no interaction data for it.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Bladder Up may be worth considering if you have an enlarged prostate and want to explore a supplement option, since pumpkin seed oil is possibly effective for that condition. If you take lithium, you'll need to check with your doctor or pharmacist first — this product may affect how your body handles the drug.
Pregnant or breastfeeding? There isn't enough data to be sure it's safe, so talk it over with your doctor or pharmacist for personalized advice.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bladder Up, straight from the product label.
| Brand | Cardiovascular Research |
|---|---|
| Net contents | 90 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 283451 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bladder Up by Cardiovascular Research, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Calories from Fat | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 2% |
| Polyunsaturated Fat | 0.5 Gram(s) | -- |
| Pumpkin seed Oil | 1000 mg | -- |
Other ingredients: Gelatin, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Formula
Bladder Up is a scientifically designed supplement containing a rich source of pumpkin seed oil. This unique oil is a rich source of trace minerals, essential fatty acids, vitamins A, B and E, and contains naturally occurring phytosterols.
(Cucurbita pepo)
Formulation
Research suggests the beneficial role of phytosterols in bladder health. Cold processing methods are used in the extraction process to preserve the active constituents.
Suggested/Recommended/Usage/Directions
Directions Take 2 softgels daily with meals or as directed by a physician.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bladder Up by Cardiovascular Research label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bladder Up by Cardiovascular Research
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.
Pumpkin seed Oil
Interacts with1 drug
Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...
Pumpkin seed Oil monograph & interactionsOther (inactive) ingredients: Gelatin, Glycerin. These complete the product’s ingredient list but are not active constituents.
Bladder Up by Cardiovascular Research Drug Interactions
HelloPharmacist Interaction Report
Bladder Up by Cardiovascular Research contains pumpkin seed oil, which has one documented interaction we need to flag.
Pumpkin seed oil may reduce how your body excretes lithium (a mood stabilizer), which could raise lithium levels in your blood. Because lithium has a narrow therapeutic window — meaning the difference between an effective dose and a toxic one is small — this interaction is rated Moderate.
Your doctor may need to adjust your lithium dose if you start taking this supplement.
Read the full breakdown — every affected drug type, severity by severity
We couldn't check the other active ingredient, polyunsaturated fat, because we don't hold interaction data for it. If you take lithium, run your exact medications through the search tool on this page before starting Bladder Up, and let your doctor or pharmacist know you're considering this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bladder Up?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bladder Up interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Bladder Up interact with drugs. Each result below shows which ingredient is responsible. Pumpkin seed Oil
Lithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Bladder Up — through 1 ingredient. Tap an ingredient for the detail:
Pumpkin Seed OilLithium Moderate
Interaction Summary
Pumpkin might reduce excretion and increase levels of lithium.
Read the full Pumpkin Seed Oil + Lithium Carbonate (prescription Drug) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bladder Up with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Pumpkin seed Oil
Lithium
Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Bladder Up, from the product label.
Cardiovascular Research
See all Cardiovascular Research products- Name
- CARDIOVASCULAR RESEARCH, LTD.
- City
- CONCORD
- State
- CA
- ZipCode
- 94518
Bladder Up by Cardiovascular Research: Common Questions
Does Bladder Up by Cardiovascular Research interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does pumpkin seed oil really help with urinary or bladder problems?
What are the most common side effects?
Is pumpkin seed oil safe during pregnancy?
Is it safe to use while breastfeeding?
Can pumpkin seed oil cause hair loss?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bladder Up is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bladder Up’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Bladder Up's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pumpkin 5 references
- Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
- Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
- Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
- Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
- Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC