Max Energee Ingredients & Drug Interactions
by Maxi Health
What is this page for?
First and foremost: checking Max Energee against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Max Energee is a dietary supplement by Maxi Health with 8 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,231 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Eleutherococcus senticosus Rhizome Extract, Chlorella. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Max Energee by Maxi Health
Ask about any prescription or over-the-counter medication and we check it for interactions with Max Energee by Maxi Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Max Energee by Maxi Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Max Energee contains five active ingredients. Bee pollen is a nutrient-dense powder from honeybees.
Chlorella is a single-celled green algae. Eleuthero—also called Siberian ginseng—is a plant root extract.
Octacosanol is a waxy compound derived from plants. The product also contains Other Carbohydrate, an ingredient we have no specific data on.
The remaining ingredients are inactive—fillers, binders, enzymes (bromelain, papain, lipase, amylase, and protease), and the capsule material itself.
Does it work?
Leans against
The evidence on Max Energee's ingredients is mixed and mostly limited. Bee pollen is rated Possibly Ineffective for athletic performance and has insufficient evidence for hay fever, amenorrhea, prostate health, and breast cancer-related hot flashes.
Chlorella is Possibly Effective for pregnancy-related iron deficiency but has insufficient evidence for brain tumors, fatty liver disease, depression, and fatigue. Eleuthero is Possibly Effective for genital herpes but insufficient for Mediterranean fever, bipolar disorder, osteoporosis, and chronic fatigue.
Octacosanol has insufficient evidence for ALS, athletic performance, Parkinson disease, and high cholesterol. We hold no effectiveness data for Other Carbohydrate.
How safe is it?
Well-documented data
Bee pollen is generally well tolerated but can trigger allergic reactions—sometimes serious, especially if you have seasonal pollen allergies to ragweed, chrysanthemums, daisies, or related plants. Rare serious effects include liver inflammation, kidney problems, and anaphylaxis.
Chlorella is generally well tolerated short-term but may cause nausea, diarrhea, constipation, stomach cramping, gas, fatigue, skin photosensitivity, and—rarely—allergic reactions or anaphylaxis. Eleuthero is generally well tolerated short-term; common effects include diarrhea, stomach upset, headache, nausea, rash, and nervousness (especially at higher doses), and it may raise blood pressure.
Octacosanol has limited long-term safety data but may cause headache, dizziness, drowsiness, irritability, insomnia, itching, or skin rash—all uncommon. Bee pollen should be avoided in pregnancy due to concern about uterine stimulation, and both bee pollen and chlorella should be avoided while breastfeeding (safety data are insufficient).
Eleuthero and octacosanol also lack sufficient pregnancy and breastfeeding data—talk with your doctor or pharmacist before use if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Check with a pharmacist before taking Max Energee if you use blood thinners like warfarin, any drug metabolized by your liver (CYP1A2, CYP2C9, CYP2D6), heart medications including digoxin, beta-blockers or propranolol, diabetes medications, immunosuppressants, levodopa/carbidopa for Parkinson disease, nitroprusside, or photosensitizing drugs. No interactions are documented for the Other Carbohydrate ingredient we could not check.
The bottom line
Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Max Energee is a multi-ingredient energy supplement with documented interactions affecting over 1,200 medications. If you take a blood thinner like warfarin, any liver-metabolized medication, heart medications like digoxin, beta-blockers, diabetes drugs, immunosuppressants, or Parkinson medication, have a pharmacist check your specific meds before you start.
Talk to your doctor or pharmacist if you're pregnant, nursing, or have seasonal pollen allergies.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Max Energee, straight from the product label.
| Brand | Maxi Health |
|---|---|
| Barcode (UPC) | 753406014187 |
| Net contents | 180 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 323788 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Max Energee by Maxi Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | -- |
| Calories from Fat | 2 Calorie(s) | -- |
| Total Fat | 0.5 Gram(s) | 1% |
| Dietary Fiber | 0.2 Gram(s) | 1% |
| Protein | 1 Gram(s) | 2% |
| Calories from Saturated Fat | 1 Calorie(s) | -- |
| Bee Pollen, Powder | 1000 mg | -- |
| Other Carbohydrate | 0.8 Gram(s) | -- |
| Chlorella | 1000 mg | -- |
| Eleutherococcus senticosus Rhizome Extract | 200 mg | -- |
| Octacosanol | 5 mg | -- |
Other ingredients: Stearic Acid, Dicalcium Phosphate, Microcrystalline Cellulose, Calcium Carbonate, Bromelain, Papain, Lipase, Amylase, Protease, Silica, Water, Purified, Hydroxypropyl Methylcellulose, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Take two (2) tablets daily with meals, or as directed.
Precautions
If pregnant or nursing, consult your healthcare practitioner before using any dietary supplement.
Keep out of reach of children.
Storage
Store tightly closed in a cool, dry place.
Formulation
This product was manufactured in a GMP Certified Facility.
Vegetarian
Abundant energy Super whole food blend Power life from within
This product contains no animal product, soy, wheat, gluten, yeast, salt, sugar, milk, artificial flavors, colorings or preservatives.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Certified Kosher UK (Rav Shmuel Dovid Krausz (Udvarer Rav)) (Kosher) BDZ Edah Charedis - Orthodox Council of Jerusalem (Kosher)
OU (Kosher)
Enzymax base
Seals/Symbols
Manufactured in a Certified GMP Facility UK (Rav Shmuel Dovid Krausz (Udvarer Rav)) (Kosher) BDZ Edah Charedis - Orthodox Council of Jerusalem (Kosher)
OU (Kosher)
General Statements
Doctor formulated
Questions? [email protected]
Brand IP Statement(s)
Maxi Health True to total wellness
Enzymax, a vital digestive enzyme complex, is a registered trademark of Maxi Health Research Inc. Policosanol-Plus is a registered trademark of Innovation Laboratories, Inc.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Max Energee by Maxi Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Max Energee by Maxi Health
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsProtein
Calories from Saturated Fat
Bee Pollen, Powder
Interacts with2 drugs
Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most...
Bee Pollen, Powder monograph & interactionsOther Carbohydrate
Chlorella
Interacts with337 drugs
Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies sugges...
Chlorella monograph & interactionsEleutherococcus senticosus Rhizome Extract
Interacts with1,140 drugs
Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence beh...
Eleutherococcus senticosus Rhizome Extract monograph & interactionsOctacosanol
Interacts with248 drugs
Octacosanol is a waxy long-chain alcohol from plant sources that is most often promoted for exercise endurance and cholesterol support, but solid huma...
Octacosanol monograph & interactionsOther (inactive) ingredients: Stearic Acid, Dicalcium Phosphate, Microcrystalline Cellulose, Calcium Carbonate, Bromelain, Papain, Lipase, Amylase, Protease, Silica, Water, Purified, Hydroxypropyl Methylcellulose, Glycerin. These complete the product’s ingredient list but are not active constituents.
Max Energee by Maxi Health Drug Interactions
HelloPharmacist Interaction Report
Max Energee by Maxi Health contains five ingredients, and we've documented interactions with a significant number of medications.
The most serious concern is with blood thinners (anticoagulants): bee pollen and chlorella both interact with warfarin at Moderate severity. Bee pollen may increase bleeding risk by raising warfarin levels, while chlorella—which is rich in vitamin K—can actually reduce warfarin's effectiveness.
If you take warfarin, you'll want to check this product before starting.
Read the full breakdown — every affected drug type, severity by severity
Several other drug types are affected at Moderate severity. Eleuthero may interfere with drugs metabolized by your liver (CYP1A2, CYP2C9, and CYP2D6 substrates), P-glycoprotein substrates, blood thinners and antiplatelet drugs, immunosuppressants, diabetes medications, and digoxin—a heart medication where even small changes in levels matter.
Octacosanol may add to the blood pressure-lowering effects of beta-blockers and propranolol, increase bleeding risk with anticoagulants and antiplatelet drugs, affect diabetes medications, worsen Parkinson symptoms if you take levodopa/carbidopa, and enhance nitroprusside's blood pressure effects. Chlorella may also have additive effects with photosensitizing drugs (medications that make your skin sun-sensitive).
One ingredient, Other Carbohydrate, we couldn't check—no interaction data is on file for it.
Additionally, check your exact medications with the search tool on this page before starting Max Energee. Altogether, these interactions span 1,288 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Max Energee?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Max Energee interact with 2,231 drugs. Click any drug to see the details.
5 of the 8 ingredients in Max Energee interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Eleutherococcus senticosus Rhizome Extract Chlorella Octacosanol Bee Pollen, Powder
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Read the full Eleutherococcus Senticosus Rhizome Extract + 6-mercaptopurine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Eleutherococcus Senticosus Rhizome Extract + Abciximab interactionOctacosanolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Read the full Octacosanol + Abciximab interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
OctacosanolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Read the full Octacosanol + Abrocitinib interactionEleutherococcus Senticosus Rhizome ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
Read the full Eleutherococcus Senticosus Rhizome Extract + Abrocitinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acalabrutinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acarbose interactionOctacosanolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, octacosanol might have additive effects when used in combination with antidiabetes drugs.
Read the full Octacosanol + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
OctacosanolBeta-blockers Moderate
Interaction Summary
Theoretically, concomitant use of octacosanol with beta-blockers might result in additive hypotensive effects.
Read the full Octacosanol + Acebutolol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
OctacosanolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Read the full Octacosanol + Acenocoumarol interactionEleutherococcus Senticosus Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acenocoumarol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acepromazine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Aspirin interactionOctacosanolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Read the full Octacosanol + Acetaminophen, Aspirin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Aspirin, Caffeine interactionOctacosanolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Read the full Octacosanol + Acetaminophen, Aspirin, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionEleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Butalbital interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Butalbital, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Butalbital, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Caffeine, Isometheptene interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Max Energee — through 2 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Caffeine, Pyrilamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Max Energee — through 3 ingredients. Tap an ingredient for the detail:
Eleutherococcus Senticosus Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleutherococcus Senticosus Rhizome Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Max Energee with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Eleutherococcus senticosus Rhizome Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that a constituent of eleuthero, dihydroxybenzoic acid, appears to inhibit platelet aggregation. Concomitant use with anticoagulant or antiplatelet drugs might increase the risk of bleeding. This effect has not been reported in humans.
Antidiabetes Drugs
Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.
Animal research suggests that certain constituents of eleuthero have hypoglycemic activity in both healthy and diabetic animals. A small study in adults with type 2 diabetes also shows that taking eleuthero for 3 months can lower blood glucose levels. However, one very small study in healthy individuals shows that taking powdered eleuthero 3 grams, 40 minutes prior to a 75-gram oral glucose tolerance test, significantly increases postprandial blood glucose levels when compared with placebo. These contradictory findings might be due to patient-specific variability and variability in active ingredient ratios.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggest that standardized extracts of eleuthero inhibit CYP1A2. This effect has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2C9. This effect has not been reported in humans.
Digoxin (Lanoxin)
Eleuthero might increase serum digoxin levels and increase the risk of side effects.
In one case report, a 74-year-old male who was stabilized on digoxin presented with an elevated serum digoxin level after starting an eleuthero supplement, without symptoms of toxicity. After stopping the supplement, serum digoxin levels returned to normal. It is not clear whether this was due to a pharmacokinetic interaction or to interference with the digoxin assay. Although the product was found to be free of digoxin and digitoxin, it was not tested for other contaminants.
Immunosuppressants
Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Animal and in vitro research shows that eleuthero extracts have immunomodulatory effects, including increasing cellular and humoral activity.
P-Glycoprotein Substrates
Theoretically, eleuthero might increase levels of P-glycoprotein substrates.
In vitro research suggests that eleuthero can inhibit the multi-drug transporter protein, P-glycoprotein. However, it is too soon to tell if this is clinically important. This interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2D6. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP2D6 drug metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP3A4. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP3A4 drug metabolism.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, eleuthero might decrease levels of drugs metabolized by OATP.
In vitro research suggests that eleuthero inhibits OATP2B1, which might reduce the bioavailability of oral drugs that are substrates of OATP2B1. Due to the weak inhibitory effect identified in this study, this interaction is not likely to be clinically significant.
Chlorella
Photosensitizing Drugs
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.
Warfarin (Coumadin)
Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.
Octacosanol
Anticoagulant/Antiplatelet Drugs
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Octacosanol is the main component of policosanol. Some clinical research shows that taking policosanol 10-50 mg daily for 7-15 days can inhibit platelet aggregation in healthy patients. However, one clinical trial shows that taking policosanol 10 mg twice daily for 2 weeks prior to initiating warfarin does not affect warfarin pharmacokinetics or warfarin response. Furthermore, a study in patients undergoing percutaneous coronary intervention with a drug-eluting stent found that taking policosanol 40 mg plus clopidogrel and aspirin daily for 30 days modestly reduced the risk for minor bleeding events when compared with taking clopidogrel and aspirin alone.
Antidiabetes Drugs
Theoretically, octacosanol might have additive effects when used in combination with antidiabetes drugs.
Octacosanol is the main component of policosanol. In humans, policosanol can decrease blood glucose. It is not clear if these effects occur with the use of octacosanol.
Beta-Blockers
Theoretically, concomitant use of octacosanol with beta-blockers might result in additive hypotensive effects.
Octacosanol is the main component of policosanol. Clinical research shows that policosanol 5 mg daily can have additive blood pressure-lowering effects in patients with hypertension who are taking beta-blockers. Also, animal research shows that policosanol can increase the hypotensive effects of propranolol. It is not clear if these effects occur with the use of octacosanol.
Levodopa/Carbidopa (Sinemet)
Concomitant use may worsen symptoms of Parkinson disease.
One small clinical study suggests that octacosanol might worsen dyskinesias and increase nervous tension in some patients being treated with levodopa/carbidopa.
Nitroprusside (Nitropress)
Theoretically, octacosanol might enhance the hypotensive effects of nitroprusside.
Octacosanol is the main component of policosanol. Animal research shows that taking policosanol along with nitroprusside can increase the hypotensive effects of nitroprusside. It is not clear if these effects occur with the use of octacosanol.
Propranolol (Inderal)
Theoretically, octacosanol might enhance the hypotensive effects of propranolol.
Octacosanol is the main component of policosanol. Animal research shows that taking policosanol along with propranolol can increase the blood pressure-lowering effects of propranolol. It is not clear if these effects occur with the use of octacosanol.
Warfarin (Coumadin)
Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically significant.
Octacosanol is the main component of policosanol. Some clinical research shows that taking policosanol 10-50 mg daily for 7-15 days can inhibit platelet aggregation in healthy patients. Therefore, there is concern that taking policosanol with warfarin might increase the risk of bruising and bleeding. However, one clinical trial shows that taking policosanol 10 mg twice daily for 2 weeks prior to warfarin dosing does not affect warfarin pharmacokinetics or warfarin response. It is not clear if these effects occur with the use of octacosanol.
Bee Pollen, Powder
Warfarin (Coumadin)
There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
In one case report, a patient on warfarin had a stable international normalized ratio (INR) of 1.9-3.3 for 9 months. The patient's INR was found to be 7.1 after starting bee pollen granules one teaspoon twice daily for approximately one month. The patient's warfarin dose was decreased by approximately 11% in order to return the INR to the therapeutic range while continuing the bee pollen supplement.
Brand information
Manufacturer and brand details for Max Energee, from the product label.
Maxi Health
See all Maxi Health products- Name
- Maxi Health
- City
- Brooklyn
- State
- N.Y.
- Phone Number
- 800-544-6294
- Web Address
- www.maxihealth.com
Max Energee by Maxi Health: Common Questions
Does Max Energee by Maxi Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does bee pollen in this product affect warfarin?
I take chlorella for iron. Does this product's chlorella dose matter?
Can I take Max Energee while pregnant or breastfeeding?
What are the most common side effects I might notice?
Does eleuthero work for chronic fatigue?
Are there fillers or just the active ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Max Energee is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Max Energee’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographBee Pollen
Interacts with 2 drugsBee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can caus...
Read the full Bee Pollen monograph → Herb & supplement monographChlorella
Interacts with 337 drugsChlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...
Read the full Chlorella monograph → Herb & supplement monographEleuthero
Interacts with 1,140 drugsEleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence behind these uses is limited and mixed, so...
Read the full Eleuthero monograph → Herb & supplement monographOctacosanol
Interacts with 248 drugsOctacosanol is a waxy long-chain alcohol from plant sources that is most often promoted for exercise endurance and cholesterol support, but solid human evidence is limited and results are mi...
Read the full Octacosanol monograph →Sources & How We Checked
Max Energee's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 86 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Bee Pollen 15 references
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Shad JA, Chinn CG, Brann OS. Acute hepatitis after ingestion of herbs. South Med J 1999;92:1095-7. PubMed
- Puente S, Iniguez A, Subirats M, et al. [Eosinophilic gastroenteritis caused by bee pollen sensitization]. Med Clin (Barc) 1997;108:698-700.
- Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
- Cohen SH, Yunginger JW, Rosenberg N, Fink JN. Acute allergic reaction after composite pollen ingestion. J Allergy Clin Immunol 1979;64:270-4. PubMed
- Hurren KM, Lewis CL. Probable interaction between warfarin and bee pollen. Am J Health Syst Pharm 2010;67:2034-7. PubMed
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