Memory Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Memory against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Memory is a dietary supplement by Organic India with 2 active ingredients. Its ingredients are commonly taken for memory and cognitive support, anxiety and stress, adhd symptoms.Based on those ingredients, 1,192 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacopa, Gotu Kola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Memory by Organic India
Ask about any prescription or over-the-counter medication and we check it for interactions with Memory by Organic India — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Memory by Organic India
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Organic India Memory contains two active herbal ingredients: bacopa and gotu kola. Bacopa has a long history in traditional medicine and is included here for cognitive support.
Gotu kola, also known as Centella asiatica, is another traditional herb added to support brain and circulation function. The capsule itself is made from pullulan, a plant-derived inactive ingredient.
Does it work?
Leans against
The evidence for bacopa in conditions like Alzheimer disease, ADHD, cognitive function, and back pain is rated insufficient—meaning we don't yet have reliable data to say whether it works for these purposes. Gotu kola fares slightly better: it's rated possibly effective for venous insufficiency (circulation problems in the legs) and possibly effective for burns, but it's rated possibly ineffective for cognitive function and Alzheimer disease, and there's insufficient evidence for anxiety.
The bottom line is that neither ingredient has strong evidence backing the typical 'memory' and cognition claims made in marketing.
How safe is it?
Well-documented data
Both bacopa and gotu kola are generally well tolerated in short-term use, though long-term safety data are limited. Bacopa can cause gastrointestinal upset—abdominal cramps, diarrhea, nausea, and headache occur in clinical trials, with digestive complaints reported in 12% to 30% of users.
It's also been reported to cause drowsiness, insomnia, and vivid dreams in some people. Gotu kola's most common side effects are gastric irritation and nausea; there is a rare concern about liver toxicity, though clinical trials at reasonable doses haven't shown liver damage.
Because of insufficient pregnancy and breastfeeding data, the safety information advises against bacopa during both pregnancy and breastfeeding, and advises against gotu kola during pregnancy and breastfeeding as well.
Meds to double-check
Moderate interaction found
Before taking Organic India Memory, check with your doctor or pharmacist if you take any medications processed by your liver (a very common group that includes many statins, beta-blockers, and antidepressants), any CNS depressants like sleep aids or anti-anxiety drugs, anticholinergic drugs (for overactive bladder), cholinergic drugs (for myasthenia gravis or Alzheimer disease), thyroid hormones, hepatotoxic drugs (those that can damage the liver), or cevimeline (Evoxac). The interactions are rated Moderate, meaning they're worth taking seriously before combining.
The bottom line
Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Organic India Memory is a two-herb blend intended to support memory and cognition, but the evidence that either ingredient actually works for these purposes is insufficient or negative. More importantly, bacopa and gotu kola interact with a large number of medications—especially those processed through liver enzymes, CNS depressants, and certain specialty drugs—so this product requires a careful medication check before use.
Pregnant or breastfeeding individuals should avoid it. Talk with your own doctor or pharmacist about whether this product makes sense for you and whether it's safe to take alongside your current medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Memory, straight from the product label.
| Brand | Organic India |
|---|---|
| Net contents | 30 Daily Pack(s); 60 Vegetable Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2023 |
| DSLD ID | 300172 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Memory by Organic India, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
30 day supply New Easy open dispenser
Capsules shown actual size
Earth seer Ethical, authentic, reliable, trustworthy, holistic, socially, environmentally, economically responsible
Meet the farmers Beginning with a single farmer in 1999, the Organic India farmer partner community has grown to over 3,000 farms throughout India. Scan me Scan QR code to learn more
Formulation
Whole-herb Ayurvedic formulations, backed by science, for daily cognitive support Healthy conscious living Holistic Convenient Simple Economical Sustainable
USDA Organic
Non GMO Project Verified nongmoproject.org
Take the guesswork out of your supplement routine. Optimize cognitive function with this convenient daily pack of Ayurvedic adaptogens and nootropics. Memory Bacopa is well-known in Ayurveda for its supportive qualities toward memory and cognition.
Certified Organic by Control Union-CU 801983 Product produced and processed according to NPOP standard of India USDA-NOP NPOP/NAB/0010
Product of India For export in the USA Ayurvedic Medicine Mfg. Lic. No. A-2755
Vegan Vegetarian
Gluten free
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
USDA Organic Non GMO Project Verified nongmoproject.org Certified B Corporation
Certified Organic by Control Union-CU 801983 Product produced and processed according to NPOP standard of India USDA-NOP NPOP/NAB/0010
OU (Kosher) Halal Jamiat Ulama Halal Foundation Mumbai India 0884
Formula
Bacopa
OU (Kosher)
Halal Jamiat Ulama Halal Foundation Mumbai India 0884
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Suggested/Recommended/Usage/Directions
Suggested use: 1 pack daily with food and water.
Precautions
If pregnant or nursing consult your health physician prior to use. Warning: Reproductive harm - www.P65Warnings.ca.gov
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Memory by Organic India label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Memory by Organic India
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Bacopa
Interacts with930 drugs
Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for s...
Bacopa monograph & interactionsGotu Kola
Interacts with579 drugs
Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...
Gotu Kola monograph & interactionsOther (inactive) ingredients: Pullulan. These complete the product’s ingredient list but are not active constituents.
Memory by Organic India Drug Interactions
HelloPharmacist Interaction Report
Organic India Memory contains bacopa and gotu kola, both of which have documented interactions with medications.
The most serious concern is bacopa's potential to inhibit several liver enzymes (CYP1A2, CYP2C9, CYP2C19, and CYP3A4), which theoretically could increase levels and side effects of drugs metabolized by these pathways. This is a Moderate severity interaction.
Additionally, bacopa may interfere with anticholinergic drugs (used for overactive bladder and other conditions) and cholinergic drugs (used for myasthenia gravis and Alzheimer disease), potentially reducing their effectiveness or causing additive effects.
Read the full breakdown — every affected drug type, severity by severity
Gotu kola carries Moderate interactions with CNS depressants—sedatives, sleep aids, and anti-anxiety medications—because it may have its own sedative effects. It also theoretically could have additive liver toxicity if taken with drugs known to damage the liver, though this is based on case reports rather than controlled research.
Bacopa also has a Minor interaction with thyroid hormone, as animal data suggests it may increase thyroid hormone levels.
One ingredient, bacopa, also has a specific Moderate interaction documented with cevimeline (Evoxac), a medication for dry mouth in Sjögren syndrome; a case report described significant symptoms when combined.
Altogether, these interactions span 1,193 individual medications. Use the search tool below to check your exact medications before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Memory?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Memory interact with 1,192 drugs. Click any drug to see the details.
2 of the 2 ingredients in Memory interact with drugs. Each result below shows which ingredient is responsible. Bacopa Gotu Kola
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
BacopaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abacavir, Lamivudine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
BacopaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Abiraterone interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abiraterone Acetate interactionBacopaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
BacopaCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Bacopa + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
BacopaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Memory — through 1 ingredient. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola + Acepromazine interactionBacopaAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Aspirin interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Aspirin, Caffeine interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Butalbital interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Butalbital, Caffeine interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Acetaminophen, Butalbital, Caffeine, Codeine interactionGotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola + Acetaminophen, Butalbital, Codeine interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Butalbital, Codeine Phosphate interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionBacopaCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola + Acetaminophen, Caffeine, Codeine interactionBacopaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Caffeine, Codeine, Salicylamide interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa + Acetaminophen, Caffeine, Dihydrocodeine interactionGotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Caffeine, Isometheptene interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Caffeine, Pyrilamine interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionBacopaCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Memory — through 2 ingredients. Tap an ingredient for the detail:
BacopaAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Memory with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bacopa
Anticholinergic Drugs
Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.
Cevimeline (Evoxac)
Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.
Cholinergic Drugs
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Thyroid Hormone
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.
Gotu Kola
Cns Depressants
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.
Hepatotoxic Drugs
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.
Brand information
Manufacturer and brand details for Memory, from the product label.
Organic India
See all Organic India products- Name
- Organic India Pvt. Ltd.
- Street Address
- C-5/10, Agro Park Phase-II UPSIDC Industrial Area, Kursi Road
- City
- Barabanki
- State
- U.P.
- ZipCode
- 225302
Memory by Organic India: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Memory’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bacopa
Interacts with 930 drugsBacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for several weeks, but the evidence is limite...
Read the full Bacopa monograph → Herb & supplement monographGotu Kola
Interacts with 579 drugsGotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...
Read the full Gotu Kola monograph →Sources & How We Checked
Memory's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bacopa 12 references
- Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology 2001;156:481-4..
- Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496-503..
- Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
- Kar, A., Panda, S., and Bharti, S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol. 2002;81(2):281-285. PubMed
- Mukherjee, G. D. and Dey, C. D. Clinical trial on Brahmi. I. J.Exp.Med.Sci. 1966;10(1):5-11.
- Kar A, Pandit S, Mukherjee K, Bahadur S, Mukherjee PK. Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study. J Sci Food Agric 2017;97(1):333-40. doi: 10.1002/jsfa.7739. PubMed
- Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014;151(1):528-35. PubMed
- Ramasamy S, Kiew LV, Chung LY. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents. Molecules 2014;19(2):2588-601. PubMed
- Prabhakar S, Vishnu VY, Modi M, et al. Efficacy of Bacopa monnieri (Brahmi) and donepezil in Alzheimer's disease and mild cognitive impairment: a randomized double-blind parallel phase 2b study. Ann Indian Acad Neurol 2020;23(6):767-73. PubMed
- Acquarulo B, Tandon P, Macica CM. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report. J Med Case Rep 2022;16(1):253. PubMed
- Keegan AP, Stough C, Paris D, et al. Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderl
- Yaworski AM, Blyumin M, Chang T, Mammen AL, Greene M. Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa. Muscle Nerve 2023;67(2):E1-E3.
Gotu Kola 18 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
- Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
- Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
- Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
- Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
- Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
- Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
- Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
- Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
- Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
- Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
- Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
- Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
- Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
- Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
- Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
- Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC