Menopause Formula Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Menopause Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Menopause Formula is a dietary supplement by Dr. Tagliaferri Formulas with 10 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and stomach upset, mouth ulcers and digestive complaints.Based on those ingredients, 1,542 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycyrrhiza uralensis, Cortex Moutan Radicis, Atractylodis Macrocephalae Rhizoma. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Menopause Formula by Dr. Tagliaferri Formulas
Ask about any prescription or over-the-counter medication and we check it for interactions with Menopause Formula by Dr. Tagliaferri Formulas — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Menopause Formula by Dr. Tagliaferri Formulas
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 10 active ingredients.
- “Dr. Tagliaferri's Menopause Formula” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 7 of the 7 matched ingredients can interact with medications — Peony, Poria Mushroom, Asian Water Plantain, Licorice, Astragalus, among others.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
- For scale: 1,543 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 6 of the 7 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 7 of 7.
- General safety write-ups exist for 7 of 7.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 7 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Menopause Formula, straight from the product label.
| Brand | Dr. Tagliaferri Formulas |
|---|---|
| Net contents | 120 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Feb 26, 2014 |
| DSLD ID | 30605 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Women (not pregnant or lactating), Menopause |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Menopause Formula by Dr. Tagliaferri Formulas, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Glycyrrhiza uralensis | 0 NP | -- |
| Anemarrhena | 0 NP | -- |
| radix Astragali | 0 NP | -- |
| Dr. Tagliaferri's Menopause Formula | 1000 mg | -- |
| Radix Rehmanniae | 0 NP | -- |
| Fructus Corni Officinalis | 0 NP | -- |
| Radix Dioscoreae Oppositae | 0 NP | -- |
| Sclerotium Poriae Cocos | 0 NP | -- |
| Cortex Moutan Radicis | 0 NP | -- |
| Rhizoma Alismatis Orientalis | 0 NP | -- |
| Atractylodis Macrocephalae Rhizoma | 0 NP | -- |
Other ingredients: Vegetable Capsules, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
DR. TAGLIAFERRI'S Menopause FORMULA is safe, effective and helps: Reduce hot flashes, Reduce night sweats, Improve quality of sleep, Reduce irritability, Prevent menopausal weight gain, Maintain energy
The Doctor's Choice
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
For adults only.
DR. TAGLIAFERRI'S Menopause FORMULA is a safe and natural plant-based supplement designed to reduce symptoms associated with menopause.
Formulation
Dr. Tagliaferri's Menopause Formula is suitable for vegetarians and vegans.
FDA Statement of Identity
PHYSICIAN FORMULATED DIETARY SUPPLEMENT
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 2 capsules twice a day.
Precautions
Not for use by pregnant or lactating women.
Keep out of reach of children.
Brand IP Statement(s)
(C)2013
Seals/Symbols
HERBA BUENA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Menopause Formula by Dr. Tagliaferri Formulas label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Menopause Formula by Dr. Tagliaferri Formulas
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dr. Tagliaferri's Menopause Formula
- › Glycyrrhiza uralensis
- › Anemarrhena
- › Radix Astragali
- › Radix Rehmanniae
- › Fructus Corni Officinalis
- › Radix Dioscoreae Oppositae
- › Sclerotium Poriae Cocos
- › Cortex Moutan Radicis
- › Rhizoma Alismatis Orientalis
- › Atractylodis Macrocephalae Rhizoma
Other (inactive) ingredients: Vegetable Capsules, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Menopause Formula by Dr. Tagliaferri Formulas Drug Interactions
Menopause Formula contains 10 ingredients, and 7 of them have known drug interactions. Altogether they interact with 1,542 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Menopause Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Menopause Formula interact with 1,542 drugs. Click any drug to see the details.
7 of the 10 ingredients in Menopause Formula interact with drugs. Each result below shows which ingredient is responsible. Glycyrrhiza uralensis Cortex Moutan Radicis Atractylodis Macrocephalae Rhizoma Sclerotium Poriae Cocos Rhizoma Alismatis Orientalis Radix Rehmanniae radix Astragali
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Menopause Formula — through 1 ingredient. Tap an ingredient for the detail:
Radix AstragaliImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Radix Astragali + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Menopause Formula — through 3 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Ado-trastuzumab Emtansine interactionCortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Ado-trastuzumab Emtansine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Menopause Formula — through 2 ingredients. Tap an ingredient for the detail:
Atractylodis Macrocephalae RhizomaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodis Macrocephalae Rhizoma + Abciximab interactionCortex Moutan RadicisAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Cortex Moutan Radicis + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Menopause Formula — through 3 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Abemaciclib interactionGlycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Abemaciclib interactionAtractylodis Macrocephalae RhizomaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Menopause Formula — through 3 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Abiraterone interactionGlycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Abiraterone interactionAtractylodis Macrocephalae RhizomaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Menopause Formula — through 3 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Abiraterone Acetate interactionCortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Abiraterone Acetate interactionAtractylodis Macrocephalae RhizomaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Cortex Moutan Radicis + Abrocitinib interactionGlycyrrhiza UralensisCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
Read the full Glycyrrhiza Uralensis + Abrocitinib interactionRadix AstragaliImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Radix Astragali + Abrocitinib interactionAtractylodis Macrocephalae RhizomaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodis Macrocephalae Rhizoma + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Menopause Formula — through 3 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Acalabrutinib interactionGlycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acalabrutinib interactionAtractylodis Macrocephalae RhizomaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Menopause Formula — through 2 ingredients. Tap an ingredient for the detail:
Radix RehmanniaeAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Radix Rehmanniae + Acarbose interactionRadix AstragaliAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Radix Astragali + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Menopause Formula — through 2 ingredients. Tap an ingredient for the detail:
Radix RehmanniaeAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Radix Rehmanniae + Acebutolol interactionGlycyrrhiza UralensisAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Glycyrrhiza Uralensis + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Menopause Formula — through 2 ingredients. Tap an ingredient for the detail:
Atractylodis Macrocephalae RhizomaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodis Macrocephalae Rhizoma + Acenocoumarol interactionCortex Moutan RadicisAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Cortex Moutan Radicis + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Menopause Formula — through 1 ingredient. Tap an ingredient for the detail:
Sclerotium Poriae CocosCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Sclerotium Poriae Cocos + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen interactionGlycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Atractylodis Macrocephalae RhizomaAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Aspirin interactionCortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Aspirin interactionGlycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Aspirin interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Cortex Moutan Radicis + Acetaminophen, Aspirin, Caffeine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Aspirin, Caffeine interactionGlycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Aspirin, Caffeine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGlycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Butalbital interactionGlycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Butalbital interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Butalbital interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Butalbital, Caffeine interactionGlycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Butalbital, Caffeine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Butalbital, Caffeine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Butalbital, Caffeine, Codeine interactionCortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Acetaminophen, Butalbital, Caffeine, Codeine interactionSclerotium Poriae CocosCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Butalbital, Caffeine, Codeine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Butalbital, Caffeine, Codeine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Butalbital, Codeine interactionSclerotium Poriae CocosCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Butalbital, Codeine interactionGlycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Butalbital, Codeine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Butalbital, Codeine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Sclerotium Poriae CocosCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Butalbital, Codeine Phosphate interactionCortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Butalbital, Codeine Phosphate interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Butalbital, Codeine Phosphate interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Butalbital, Codeine Phosphate interactionGlycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSclerotium Poriae CocosAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Caffeine, Codeine interactionCortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Acetaminophen, Caffeine, Codeine interactionSclerotium Poriae CocosCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Caffeine, Codeine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Caffeine, Codeine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Sclerotium Poriae CocosCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Caffeine, Codeine, Salicylamide interactionCortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Acetaminophen, Caffeine, Codeine, Salicylamide interactionGlycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Caffeine, Codeine, Salicylamide interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Caffeine, Dihydrocodeine interactionCortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Caffeine, Dihydrocodeine interactionSclerotium Poriae CocosCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Caffeine, Dihydrocodeine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Caffeine, Dihydrocodeine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Menopause Formula — through 4 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Caffeine, Isometheptene interactionCortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Acetaminophen, Caffeine, Isometheptene interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Caffeine, Isometheptene interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Acetaminophen, Caffeine, Pyrilamine interactionSclerotium Poriae CocosAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Caffeine, Pyrilamine interactionGlycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, Diuretic Drugs +1 Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Caffeine, Pyrilamine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Caffeine, Pyrilamine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionSclerotium Poriae CocosAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionCortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAtractylodis Macrocephalae RhizomaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Glycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionSclerotium Poriae CocosAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCortex Moutan RadicisCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Cortex Moutan Radicis + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Menopause Formula — through 5 ingredients. Tap an ingredient for the detail:
Cortex Moutan RadicisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Cortex Moutan Radicis + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionSclerotium Poriae CocosAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Sclerotium Poriae Cocos + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionGlycyrrhiza UralensisCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Glycyrrhiza Uralensis + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionRhizoma Alismatis OrientalisNephrotoxic Drugs Minor
Interaction Summary
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body.
Read the full Rhizoma Alismatis Orientalis + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAtractylodis Macrocephalae RhizomaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodis Macrocephalae Rhizoma + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Menopause Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Glycyrrhiza uralensis
Antihypertensive Drugs
Theoretically, licorice might reduce the effects of antihypertensive drugs.
In human research, licorice increases blood pressure in a dose-dependent manner.
Cisplatin (Platinol-Aq)
Theoretically, licorice might reduce the effects of cisplatin.
In animal research, licorice diminished the therapeutic efficacy of cisplatin.
Corticosteroids
Theoretically, concomitant use of licorice and corticosteroids might increase the side effects of corticosteroids.
Case reports suggest that concomitant use of licorice and oral corticosteroids, such as hydrocortisone, can potentiate the duration of activity and increase blood levels of corticosteroids. Additionally, in one case report, a patient with neurogenic orthostatic hypertension stabilized on fludrocortisone 0.1 mg twice daily developed pseudohyperaldosteronism after recent consumption of large amounts of black licorice.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
In vitro research shows that licorice extract and glabridin, a licorice constituent, inhibit CYP2B6 isoenzymes. Licorice extract from the species G. uralensis seems to inhibit CYP2B6 isoenzymes to a greater degree than G. glabra extract in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2B6; however, these interactions have not yet been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
In vitro, licorice extracts from the species G. glabra and G. uralensis inhibit CYP2C19 isoenzymes in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C19; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
In vitro, licorice extract from the species G. glabra and G. uralensis inhibits CYP2C8 isoenzymes. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C8; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
There is conflicting evidence about the effect of licorice on CYP2C9 enzyme activity. In vitro research shows that extracts from the licorice species G. glabra and G. uralensis moderately inhibit CYP2C9 isoenzymes. However, evidence from an animal model shows that licorice extract from the species G. uralensis can induce hepatic CYP2C9 activity. Until more is known, licorice should be used cautiously in people taking CYP2C9 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Pharmacokinetic research shows that the licorice constituent glycyrrhizin, taken in a dosage of 150 mg orally twice daily for 14 days, modestly decreases the area under the concentration-time curve of midazolam by about 20%. Midazolam is a substrate of CYP3A4, suggesting that glycyrrhizin modestly induces CYP3A4 activity. Animal research also shows that licorice extract from the species G. uralensis induces CYP3A4 activity. However, licorice extract from G. glabra species appear to inhibit CYP3A4-induced metabolism of testosterone in vitro. It is thought that the G. glabra inhibits CYP3A4 due to its constituent glabridin, which is a moderate CYP3A4 inhibitor in vitro and not present in other licorice species. Until more is known, licorice should be used cautiously in people taking CYP3A4 substrates.
Digoxin (Lanoxin)
Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Overuse or misuse of licorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
Diuretic Drugs
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Overuse of licorice might compound diuretic-induced potassium loss. In one case report, a 72-year-old male with a past medical history of hypertension, type 2 diabetes, hyperlipidemia, arrhythmia, stroke, and hepatic dysfunction was hospitalized with severe hypokalemia and uncontrolled hypertension due to pseudohyperaldosteronism. This was thought to be provoked by concomitant daily consumption of a product containing 225 mg of glycyrrhizin, a constituent of licorice, and hydrochlorothiazide 12.5 mg for 1 month.
Estrogens
Theoretically, licorice might increase or decrease the effects of estrogen therapy.
Theoretically, licorice might interfere with estrogen therapy due to estrogenic and anti-estrogenic effects.
Loop Diuretics
Theoretically, loop diuretics might increase the mineralocorticoid effects of licorice.
Theoretically, loop diuretics might enhance the mineralocorticoid effects of licorice by inhibiting the enzyme that converts cortisol to cortisone; however, bumetanide (Bumex) does not appear to have this effect.
Midazolam (Versed)
Theoretically, licorice might decrease levels of midazolam.
In humans, the licorice constituent glycyrrhizin appears to moderately induce the metabolism of midazolam. This is likely due to induction of cytochrome P450 3A4 by licorice. Until more is known, licorice should be used cautiously in people taking midazolam.
P-Glycoprotein Substrates
Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
In vitro research shows that licorice can increase P-glycoprotein activity.
Paclitaxel (Abraxane, Onxol)
Theoretically, licorice might decrease plasma levels and clinical effects of paclitaxel.
Multiple doses of licorice taken concomitantly with paclitaxel might reduce the effectiveness of paclitaxel. Animal research shows that licorice 3 grams/kg given orally for 14 days before intravenous administration of paclitaxel decreases the exposure to paclitaxel and increases its clearance. Theoretically, this occurs because licorice induces cytochrome P450 3A4 enzymes, which metabolize paclitaxel. Notably, a single dose of licorice did not affect exposure or clearance of paclitaxel.
Warfarin (Coumadin)
Theoretically, licorice might decrease plasma levels and clinical effects of warfarin.
Licorice seems to increase metabolism and decrease levels of warfarin in animal models. This is likely due to induction of cytochrome P450 2C9 (CYP2C9) metabolism by licorice. Advise patients taking warfarin to avoid taking licorice.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that licorice induces CYP1A2 enzymes.
Methotrexate (Trexall, Others)
Theoretically, licorice might increase levels of methotrexate.
Animal research suggests that intravenous administration of glycyrrhizin, a licorice constituent, and high-dose methotrexate may delay methotrexate excretion and increase systemic exposure, leading to transient elevations in liver enzymes and total bilirubin. This interaction has not yet been reported in humans.
Cortex Moutan Radicis
Anticoagulant/Antiplatelet Drugs
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.
Clozapine (Clozaril)
Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.
Contraceptive Drugs
Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Estrogens
Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.
Phenytoin (Dilantin)
Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.
Atractylodis Macrocephalae Rhizoma
Anticoagulant/Antiplatelet Drugs
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.
Aromatase Inhibitors
Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.
Hexobarbital
Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.
Sclerotium Poriae Cocos
Anticholinergic Drugs
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cholinergic Drugs
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cns Depressants
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.
Rhizoma Alismatis Orientalis
Nephrotoxic Drugs
Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body. However, using a higher dose of the extract, at 33.3 grams/kg orally for 60 days, has been linked to kidney issues, as indicated by increased blood urea nitrogen levels, and enlargement of the liver and kidneys. Additionally, two components of Asian water plantain, alisol A and alisol B, when given in doses of 400 mg/kg daily and 500 mg/kg daily respectively for 6 months, have been found to increase the production of markers that suggest potential kidney damage from certain medications. While these findings suggest there is very little risk that Asian water plantain may interact with drugs that are harmful to the kidneys, caution is still advised if combined with known nephrotoxic drugs (source: pubmed.ncbi.nlm.nih.gov/28408883/)
Radix Rehmanniae
Antidiabetes Drugs
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.
Antihypertensive Drugs
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).
radix Astragali
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Brand information
Manufacturer and brand details for Menopause Formula, from the product label.
Dr. Tagliaferri Formulas
See all Dr. Tagliaferri Formulas products- Name
- Herba Buena
- City
- San Anselmo
- State
- CA
- ZipCode
- 94979
Menopause Formula by Dr. Tagliaferri Formulas: Common Questions
Does Menopause Formula by Dr. Tagliaferri Formulas interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Menopause Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Licorice
Interacts with 1,040 drugsLicorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regular licorice contains glycyrrhizin, whic...
Read the full Licorice monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph → Herb & supplement monographRehmannia
Interacts with 258 drugsRehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...
Read the full Rehmannia monograph → Herb & supplement monographPoria Mushroom
Interacts with 417 drugsPoria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...
Read the full Poria Mushroom monograph → Herb & supplement monographPeony
Interacts with 811 drugsPeony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combination formulas. Human evidence for most uses is lim...
Read the full Peony monograph → Herb & supplement monographAsian Water Plantain
Interacts with 355 drugsAsian water plantain (Ze Xie) is a rhizome long used in traditional Chinese medicine, mainly as a diuretic and for fluid retention. Modern evidence is mostly limited to laboratory and animal...
Read the full Asian Water Plantain monograph → Herb & supplement monographAtractylodes
Interacts with 801 drugsAtractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as part of multi-herb formulas. Modern resea...
Read the full Atractylodes monograph →Sources & How We Checked
Menopause Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 133 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Licorice 92 references
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- Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? J Hum Hypertens 1995;9:345-8.
- Armanini D, Lewicka S, Pratesi C, et al. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. J Endocrinol Invest 1996;19:624-9. PubMed
- Zhang YD, Lorenzo B, Reidenberg MM. Inhibition of 11 beta hydroxysteroid dehydrogenase obtained from guinea pig kidney by furosemide, naringenin and some other compounds. J Steroid Biochem Mol Biol 1994;49:81-5.
- Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. Birth outcome in relation to licorice consumption during pregnancy. Am J Epidemiol 2001;153:1085-8. PubMed
- Sigurjonsdottir HA, Franzson L, Manhem K, et al. Liquorice-induced rise in blood pressure: a linear dose-response relationship. J Hum Hypertens 2001;15:549-52. PubMed
- Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
- Kent UM, Aviram M, Rosenblat M, Hollenberg PF. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. Drug Metab Dispos 2002;30:709-15.. PubMed
- Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Clin Neurol Neurosurg 2003;105:286-7.. PubMed
- Strandberg TE, Andersson S, Jarvenpaa AL, et al. Preterm birth and licorice consumption during pregnancy. Am J Epidemiol 2002;156:803-5.. PubMed
- Hussain RM. The sweet cake that reaches parts other cakes can't! Postgrad Med J 2003;79:115-6.. PubMed
- Morris DJ, Davis E, Latif SA. Licorice, tobacco chewing, and hypertension. N Engl J Med 1990;322:849-50. PubMed
- Quinkler M, Stewart PM. Hypertension and the cortisol-cortisone shuttle. J Clin Endocrinol Metab 2003;88:2384-92. PubMed
- Westman EC, Guthrie GP. Licorice, tobacco chewing, and hypertension. N Engl J Med 1990;322:850. PubMed
- Mu Y, Zhang J, Zhang S, et al. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. J Pharmacol Exp Ther 2006;316:1369-77. PubMed
- Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Intern Med 2007;46:575-8. PubMed
- Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). Am J Psychiatry 1994;151:617-8. PubMed
- de Klerk GJ, Nieuwenhuis G, Beutler JJ. Hypokalaemia and hypertension associated with use of liquorice flavoured chewing gum. BMJ 1997;314:731-2.
- Dellow EL, Unwin RJ, Honour JW. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. Nephol Dial Transplant 1999;14:218-20. PubMed
- Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Mayo Clin Proc 2003;78:767-8. PubMed
- Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. J Intern Med 1999;245:307-10.
- Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. The old lady who liked liquorice: hypertension due to chronic intoxication in a memory-impaired patient. Neth J Med 2005;63:149-50.
- Lin SH, Yang SS, Chau T, Halperin ML. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Am J Med Sci 2003;325:153-6. PubMed
- van den Bosch AE, van der Klooster JM, Zuidgeest DM, et al. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. Neth J Med 2005;63:146-8.
- van Uum SH. Liquorice and hypertension. Neth J Med 2005;63:119-20.
- Russo S, Mastropasqua M, Mosetti MA, et al. Low doses of liquorice can induce hypertension encephalopathy. Am J Nephrol 2000;20:145-8. PubMed
- Stormer FC, Reistad R, Alexander J. Glycyrrhizic acid in liquorice - evaluation of health hazard. Food Chem Toxicol 1993;31:303-12. PubMed
- Sontia B, Mooney J, Gaudet L, Touyz RM. Pseudohyperaldosteronism, liquorice, and hypertension. J Clin Hypertens (Greenwich) 2008;10:153-7. PubMed
- Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. Phytother Res 2008;22:563-5. PubMed
- Lapi F, Gallo E, Bernasconi S, et al. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. Br J Clin Pharmacol 2008;66:572-4. PubMed
- Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. Endocrinol Jpn 1990;37:331-41. PubMed
- Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. Lancet 1990;335(8697):1060-3. PubMed
- Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. Klin Wochenschr 1983;61:303-5. PubMed
- Hukkanen J, Ukkola O, Savolainen MJ. Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. Blood Press 2009;18:192-5. PubMed
- Bisogni V, Rossi GP, Calò LA. Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. Blood Press. 2014 Jun;23(3):189-92. PubMed
- Dehours E, Vallé B, Rougé-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. J Telemed Telecare. 2013 Jun;19(4):227-8. PubMed
- Kormann R, Languille E, Amiot HM, Hertig A. Dying for a cup of tea. BMJ Case Rep. 2012 Oct 19;2012. PubMed
- Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Ann Noninvasive Electrocardiol. 2013 Nov;18(6):593-6. PubMed
- Räikkönen K, Seckl JR, Heinonen K, Pyhälä R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Järvenpää AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis fu
- Robles BJ, Sandoval AR, Dardon JD, Blas CA. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). BMJ Case Rep. 2013 Sep 19;2013. PubMed
- Chamberlain, J. J. and Abolnik, I. Z. Pulmonary edema following a licorice binge. West J Med 1997;167(3):184-185.
- Barrella, M., Lauria, G., Quatrale, R., and Paolino, E. Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. Ital.J Neurol.Sci 1997;18(4):217-220. PubMed
- Fugh-Berman, A. Herb-drug interactions. Lancet 2000;355(9198):134-138. PubMed
- Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. Cardiovasc.Drugs Ther 1998;12(6):59 PubMed
- van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. J Gastroenterol Hepatol 199 PubMed
- Lozano, P., Flores, D., Martinez, S., Artigues, I., Rimbau, E. M., and Gomez, F. Upper limb ischemia induced by chronic licorice ingestion. J Cardiovasc.Surg (Torino) 2000;41(4):631-632.
- Brouwers, A. J. and van der, Meulen J. ['Licorice hypertension' also caused by licorice tea]. Ned.Tijdschr Geneeskd. 4-14-2001;145(15):744-747.
- van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C. Am J Gastroenterol 2001;96(8):2432-2437. PubMed
- Sigurjonsdottir, H. A., Manhem, K., Axelson, M., and Wallerstedt, S. Subjects with essential hypertension are more sensitive to the inhibition of 11 beta-HSD by liquorice. J Hum Hypertens 2003;17(2):125-131.
- Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. Report of 2 cases and review of the literature. Eur Neurol 1992;32(1):44-51. PubMed
- Chen, M. F., Shimada, F., Kato, H., Yano, S., and Kanaoka, M. Effect of oral administration of glycyrrhizin on the pharmacokinetics of prednisolone. Endocrinol Jpn 1991;38(2):167-174. PubMed
- Lee, C. K., Park, K. K., Lim, S. S., Park, J. H., and Chung, W. Y. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. Biol Pharm Bull 2007;30(11):2191-2195. PubMed
- Isaia, G. C., Pellissetto, C., Ravazzoli, M., and Tamone, C. Acute adrenal crisis and hypercalcemia in a patient assuming high liquorice doses. Minerva Med 2008;99(1):91-94.
- Bocker, D. and Breithardt, G. [Induction of arrhythmia by licorice abuse]. Z Kardiol 1991;80(6):389-391.
- Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption. J Peripher.Nerv.Syst. 2009;14(1):64-65. PubMed
- Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. Effect of glycyrrhizin on the activity of CYP3A enzyme in humans. Eur J Clin Pharmacol 2010;66(8):805-810. PubMed
- Goultschin, J., Palmon, S., Shapira, L., Brayer, L., and Gedalia, I. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. A pilot study. J Clin Periodontol 1991;18(3):210-212. PubMed
- Scali, M., Pratesi, C., Zennaro, M. C., Zampollo, V., and Armanini, D. Pseudohyperaldosteronism from liquorice-containing laxatives. J Endocrinol Invest 1990;13(10):847-848. PubMed
- Chatterjee, N., Domoto-Reilly, K., Fecci, P. E., Schwamm, L. H., and Singhal, A. B. Licorice-associated reversible cerebral vasoconstriction with PRES. Neurology 2010;75(21):1939-1941. PubMed
- Imtiaz, K. E. Sweet root, bitter pill: liquorice-induced hyperaldosteronism. QJM 2011;104(12):1093-1095. PubMed
- van Beers, E. J., Stam, J., and van den Bergh, W. M. Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report. Crit Care 2011;15(1):R64. PubMed
- MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. J Clin Endocrinol Metab 1990;70(6):1637-1643. PubMed
- Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Gut 1978;19(9):779-782. PubMed
- Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. N Engl J Med 1968;278(25):1381-1383. PubMed
- Corse, F. M., Galgani, S., Gasparini, C., Giacanelli, M., and Piazza, G. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. Ital J Neurol Sci 1983;4(4):493-497. PubMed
- Berlango Jimenez A., Jimenez Murillo L., Montero Perez F. J., Munoz Avila J. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. An Med Interna 1995;12(1)
- Bernardi, M., D'Intino, P. E., Trevisani, F., Cantelli-Forti, G., Raggi, M. A., Turchetto, E., and Gasbarrini, G. Effects of prolonged ingestion of graded doses of licorice by healthy volunteers. Life Sci 1994;55(11):863-872. PubMed
- van der Zwan A. Hypertension encephalopathy after liquorice ingestion. Clin Neurol Neurosurg 1993;95(1):35-37. PubMed
- Werner, S., Brismar, K., and Olsson, S. Hyperprolactinaemia and liquorice. Lancet 2-10-1979;1(8111):319.
- Nishioka, K. and Seguchi, T. Contact allergy due to oil-soluble licorice extracts in cosmetic products. Contact Dermatitis 1999;40(1):56. PubMed
- Yoshino T, Yanagawa T, Watanabe K. Risk factors for pseudoaldosteronism with rhabdomyolysis caused by consumption of drugs containing licorice and differences between incidence of these conditions in Japan and other countries: case report and literature r
- Li G, Simmler C, Chen L, et al. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. Eur J Pharm Sci. 2017;109:182-190. PubMed
- Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. Medicine (Baltimore) 2018;97(11):e0073. PubMed
- Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. Postgrad Med 2017;129(3):329-31. PubMed
- Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. Clin Med (Lond) 2017;17(1):43-5. PubMed
- Dai DW, Singh I, Hershman JM. Lozenge-induced hypermineralcorticoid state--a unique case of licorice lozenges resulting in hypertension and hypokalemia. J Clin Hypertens (Greenwich) 2016;18(2):159-60.
- O'Connell K, Kinsella J, McMahon C, Holian J, O'Riordan S. Posterior reversible encephalopathy syndrome (PRES) associated with liquorice consumption. Ir J Med Sci 2016;185(4):945-7. PubMed
- Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. Intern Med 2017;56(2):175-9. PubMed
- Ha Y, Wang T, Li J, et al. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. Eur J Drug Metab Pharmacokinet. 2020;45(2):257-264. PubMed
- Edelman ER, Butala NM, Avery LL, Lundquist AL, Dighe AS. Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest. N Engl J Med. 2020;383(13):1263-1275. PubMed
- Wang H, Dong L, Qu F, et al. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Pharm Biol. 2020 Dec;58(1):352-356. PubMed
- Attou R, Redant S, Honore PM, Preseau T, Hantson P, De Bels D. Liquorice intoxication can lead to cardiac arrest! Case Rep Emerg Med. 2020;2020:3727682. PubMed
- Benge E, Shah P, Yamaguchi L, Josef V. Trick or Treat? Licorice-Induced Hypokalemia: A Case Report. Cureus 2020;12(11):e11656. PubMed
- Abe K, Higurashi T, Takahashi M, et al. Concomitant Use of High-dose Methotrexate and Glycyrrhizin Affects Pharmacokinetics of Methotrexate, Resulting in Hepatic Toxicity. In Vivo 2021;35(4):2163-2169. PubMed
- Awad N, Makar G, Burroughs V, Ravi P, Burroughs SR. Licorice-induced apparent mineralocorticoid excess causing persistent hypertension and hypokalemia. Acta Endocrinol (Buchar) 2020;16(4):508-510. PubMed
- Patel P, Aknouk M, Dawson A, et al. How Much Is Too Much? Exploring Pseudohyperaldosteronism in Glycyrrhizic Acid Toxicity From Chronic Licorice Root Consumption. Cureus 2021;13(7):e16454. PubMed
- Fan ZJ, Liu JM, Li XX, et al. Glycyrrhizin-Induced Pseudohyperaldosteronism: A Case Report. Chin J Integr Med 2022. PubMed
- Gatica-Ortega ME, Pastor-Nieto MA. Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. Contact Dermatitis 2021;85(4):454-455.
- Wang JB, Huang A, Wang Y, et al. Corticosteroid plus glycyrrhizin therapy for chronic drug- or herb-induced liver injury achieves biochemical and histological improvements: a randomised open-label trial. Aliment Pharmacol Ther 2022;55(10):1297-1310. PubMed
- Puaratanaarunkon T, Washrawirul C, Chuenboonngarm N, Noppakun N, Asawanonda P, Kumtornrut C. Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
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Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
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Asian Water Plantain 1 reference
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See these in context on the Asian Water Plantain monograph →
Atractylodes 6 references
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