Belladonna + Amoxicillin
Amoxicillin brand names: Amoxil Capsules, Trimox, Wymox, Amix, Amoram, and others.
We found no known interaction between Belladonna and Amoxicillin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Belladonna and Amoxicillin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Amoxicillin and Belladonna in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Belladonna safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Amoxicillin
Interactions in our licensed database are recorded against drug classes, not just single drug names. Amoxicillin is filed under 7 classifications — including penicillin, antibiotic drugs, nephrotoxic drugs. Belladonna has documented interactions with 2 drug classes — the most serious being anticholinergic drugs (moderate) and cisapride (propulsid) (moderate) — and none of Amoxicillin’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Belladonna Does Interact With Other Medications
Belladonna has 196 moderate known drug interactions in our database — Amoxicillin isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Belladonna
We haven’t checked that one against Belladonna yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Belladonna. Pick one to open its full report.
Belladonna in Pregnancy & Breastfeeding
When used orally. Belladonna can reduce milk production and is secreted into breast milk.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Amoxicillin Is Prescribed For, and What Belladonna Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Amoxicillin is a prescription medicine with approved uses on its FDA label. Belladonna is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Amoxicillin is prescribed for: Amoxicillin treats bacterial infections in both adults and children, including ear, nose, and throat infections; lower respiratory tract infections; skin and skin structure infections; and genitourinary tract infections. In adults only, amoxicillin is also used — always combined with other medications — to eradicate Helicobacter pylori (H. pylori), the bacteria behind duodenal ulcers. Getting rid of H.
Read the rest of what Amoxicillin is prescribed for
pylori has been shown to reduce the chance of those ulcers coming back. It is only effective against bacteria that are susceptible to it and will not work against viral infections like the common cold or flu.
Belladonna has been studied for:
-
Common cold studied, not established Belladonna has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Belladonna for common cold
Although there is interest in using oral belladonna for the common cold, there is insufficient reliable information about the effects of belladonna for this condition.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Amoxicillin on your own; if you are taking Belladonna for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Belladonna or Amoxicillin
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Belladonna or Amoxicillin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- How Can I Prevent Stomach Pain From Amoxicillin-Clavulanate? ›
- Can You Take Amoxicillin With Mucinex Or Sudafed? ›
- Can You Take Benzonatate With Amoxicillin? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Amoxicillin
This page covers Belladonna only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amoxicillin page lists 96 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Khat (major) and Siberian Cocklebur (major).
By severity: 6 major · 76 moderate · 14 minor.
From our pharmacist’s overview on the Amoxicillin page
“Amoxicillin, one of the most commonly prescribed antibiotics, has 96 supplement and herbal ingredients flagged against it, and six carry a major rating, which puts this list in the read-carefully category. The serious entries mostly add strain to organs the drug already touches.”
Reviewed by 2 · Jul 18, 2026
Taking Belladonna as Part of a Dietary Supplement Product? Check It for Interactions
We hold 6 real supplement products containing Belladonna, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Belladonna. Even though Belladonna itself has no known interaction with Amoxicillin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Belladonna and Amoxicillin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#457 of 1,452 supplements looked up here in the last 7 days
#36 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Belladonna reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Belladonna and Amoxicillin records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Belladonna
What is Belladonna?
- Digestive cramps and spasms
- Cold and flu symptoms (homeopathic)
- Teething pain (homeopathic)
- Motion sickness and nausea
- Excess sweating or secretions
- Pain and muscle spasm (topical plasters)
Belladonna is a highly toxic plant whose alkaloids (like atropine and scopolamine) are powerful medicines used only in carefully controlled, regulated forms. The raw plant and unregulated products can cause serious poisoning, and homeopathic versions have little proof of benefit. Never self-treat with belladonna without guidance from a doctor or pharmacist.
Atropa belladonna · Solanaceae · Leaves, roots, and berries · Homeopathic tablets and pellets, tinctures, topical plasters, and standardized prescription alkaloid extracts
An interaction check asks whether these two react with each other — it does not ask whether Belladonna is a good idea for someone in your situation. Here is what our Belladonna record says about it on its own.
Belladonna: dosing
There is no safe, established "supplement" dose of belladonna for self-care. The line between a helpful dose and a toxic dose is dangerously narrow, and the amount of alkaloid in raw plant material can vary widely.Prescription belladonna-alkaloid medicines are dosed by a doctor and pharmacist. Homeopathic products are highly diluted and labeled in their own units; follow the product label exactly and keep them away from children.Do not try to make or dose belladonna products yourself.
From our Belladonna monograph — the full record covers uses, side effects and every documented interaction.
About Amoxicillin
What Is Amoxicillin Used For?
Brand names: Amoxil Capsules, Trimox, Wymox, Amix, Amoram, Amoxident, Galenamox, Rimoxallin, Amoxil Injection
Amoxicillin treats bacterial infections in both adults and children, including ear, nose, and throat infections; lower respiratory tract infections; skin and skin structure infections; and genitourinary tract infections.
In adults only, amoxicillin is also used — always combined with other medications — to eradicate Helicobacter pylori (H. pylori), the bacteria behind duodenal ulcers. Getting rid of H. pylori has been shown to reduce the chance of those ulcers coming back. It is only effective against bacteria that are susceptible to it and will not work against viral infections like the common cold or flu.
Most-Reported Side Effects for Amoxicillin
From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Belladonna
Browse every other medication we’ve checked against Belladonna — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
196 interactions
- Diphenhydramine ›
- Glycopyrrolate ›
- Oxybutynin ›
- Ipratropium ›
- Procainamide ›
- Dimenhydrinate ›
- Lofepramine ›
- Nortriptyline ›
- Procyclidine ›
- Amantadine ›
- Desipramine ›
- Fluphenazine ›
- Hydroxyzine ›
- Hyoscyamine ›
- Meclizine ›
- Phenobarbital ›
- Scopolamine ›
- Trihexyphenidyl ›
- Trospium ›
- Atropine Sulfate ›
- Benztropine ›
- Biperiden ›
- Chlorpheniramine ›
- Chlorpromazine ›
- Clomipramine ›
- Clozapine ›
- Dexchlorpheniramine ›
- Disopyramide Phosphate ›
- Hyoscine Butylbromide ›
- Imipramine ›
- Loperamide ›
- Loxapine ›
- Prochlorperazine ›
- Propantheline ›
- Tolterodine ›
- Tripelennamine ›
- Acepromazine ›
- Aclidinium Bromide ›
- Aminoglutethimide ›
- Amitriptyline ›
- Atropine ›
- Belladonna Alkaloids (prescription Drug) ›
- Bromodiphenhydramine ›
- Buclizine ›
- Carbinoxamine Maleate ›
- Carphenazine ›
- Chlordiazepoxide ›
- Chlormezanone ›
- Chlorprothixene ›
- Cisapride ›
- Clemastine ›
- Cyclizine ›
- Cyproheptadine ›
- Darifenacin ›
- Diphenylpyraline ›
- Doxylamine Succinate ›
- Ethopropazine ›
- Glutethimide ›
- Glycopyrronium Tosylate ›
- Hydrocodone/chlorpheniramine ›
Showing 60 of 196 moderate interactions — see all 196 on the Belladonna page.
No interaction 2,633 drugs checked — show the list
We also checked Belladonna against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Ibuprofen ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Lisinopril ›
- Bendamustine ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
- Bisoprolol ›
- Levothyroxine, Liothyronine ›
Showing the 60 most looked-up of 2,633 medications checked with no known interaction — see the full Belladonna list.
Belladonna References
The 20 references that drive our Belladonna monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, et al. [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. Schweiz Med Wochenschr 1996;126:1085-98.
- Corazziari, E., Bontempo, I., and Anzini, F. Effects of cisapride on distal esophageal motility in humans. Dig Dis Sci 1989;34(10):1600-1605. PubMed
- Heindl, S., Binder, C., Desel, H., Matthies, U., Lojewski, I., Bandelow, B., Kahl, G. F., and Chemnitius, J. M. [Etiology of initially unexplained confusion of excitability in deadly nightshade poisoning with suicidal intent. Symptoms, differential diagn
- Walach, H., Koster, H., Hennig, T., and Haag, G. The effects of homeopathic belladonna 30CH in healthy volunteers -- a randomized, double-blind experiment. J.Psychosom.Res. 2001;50(3):155-160. PubMed
- Davidov, M. I. [Factors predisposing to acute urine retention in patients with prostatic adenoma]. Urologiia. 2007;(2):25-31.
- Williams HC and du Vivier A. Belladonna plaster--not as bella as it seems. Contact Dermatitis 1990;23(2):119-120.
- Stieg, R. L. Double-blind study of belladonna-ergotamine-phenobarbital for interval treatment of recurrent throbbing headache. Headache 1977;17(3):120-124. PubMed
- Shader RI and Greenblatt DJ. Uses and toxicity of belladonna alkaloids and synthetic anticholinergics. Seminars in Psychiatry 1971;3(4):449-476.
- Gabel MC. Purposeful ingestion of belladonna for hallucinatory effects. J.Pediatr. 1968;72(6):864-866. PubMed
- Goldsmith SR, Frank I, and Ungerleider JT. Poisoning from ingestion of a stramonium-belladonna mixture: flower power gone sour. J.A.M.A 4-8-1968;204(2):169-170. DOI
- Schneider, F., Lutun, P., Kintz, P., Astruc, D., Flesch, F., and Tempe, J. D. Plasma and urine concentrations of atropine after the ingestion of cooked deadly nightshade berries. J Toxicol Clin Toxicol 1996;34(1):113-117. PubMed
- Ceha LJ, Presperin C, Young E, and et al. Anticholinergic toxicity from nightshade berry poisoning responsive to physostigmine. The Journal of Emergency Medicine 1997;15(1):65-69. PubMed
- Firth D and Bentley JR. Belladonna poisoning from eating rabbit. Lancet 1921;2:901. DOI
- Cummins BM, Obetz SW, Wilson MR, and et al. Belladonna poisoning as a facet of psychodelia. Jama 1968;204(11):153. DOI
- Hamilton M and Sclare AB. Belladonna poisoning. Br Med J 1947;611-612. PubMed
- Huff ML, Fikse D, Surmaitis RM, Greenberg MR. Acute angle closure glaucoma precipitated by homeopathic eyedrops containing Atropa belladonna. Am J Emerg Med. 2021 Nov 3:S0735-6757(21)00902-5. PubMed
- Chen L, Yeung JC, Anderson DR. Anisocoria secondary to anticholinergic mydriasis from homeopathic pink eye relief drops. Clin Med Res. 2017;15(3-4):93-5. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Amoxicillin Is Linked to Lower Levels of 8 Nutrients
Natural Medicines records Amoxicillin as a medicine that can lower these. This is not an interaction with Belladonna — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Amoxicillin nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Belladonna and Amoxicillin Together: Common Questions
Is it safe to take Belladonna with Amoxicillin?
Are Belladonna and Amoxicillin used for the same thing?
How was the Belladonna and Amoxicillin combination checked?
Does Belladonna interact with any other medications?
Does Amoxicillin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Amoxicillin and Belladonna?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.