Drug & supplement interaction

Dolomite + Finafloxacin

Finafloxacin brand name: Xtoro.

Moderate Interaction
The bottom line Moderate

Dolomite has a moderate interaction with Finafloxacin. Theoretically, the magnesium in dolomite might decrease the absorption of quinolone antibiotics.

Read the full interaction report
SeverityModerate
LikelihoodProbable
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Dolomite and Finafloxacin

Here is the interaction we found between these two, with the evidence behind it.

Moderate

QUINOLONE ANTIBIOTICS

Why this applies to Finafloxacin

Finafloxacin falls under QUINOLONE ANTIBIOTICS — the group Dolomite interacts with.

Theoretically, the magnesium in dolomite might decrease the absorption of quinolone antibiotics.
Dolomite contains magnesium, which can form insoluble complexes with quinolones in the gut. Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after dolomite.
Severity Moderate Likelihood Probable Evidence D

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the thing to know if you take dolomite alongside finafloxacin (Xtoro). Finafloxacin belongs to the quinolone family of antibiotics, and these drugs have a well-known habit of grabbing onto minerals like the calcium and magnesium in dolomite. When that happens in your gut, the two clump together into a form your body can't absorb well, so less of the antibiotic actually gets into your system.

Practically speaking, that could mean a weaker antibiotic, which is a real concern when you're trying to clear an infection. The simple fix is spacing them apart: take your quinolone at least 2 hours before, or 4 to 6 hours after, the dolomite. This is based on how these drugs behave rather than hard study data, but it's an easy precaution. One note: Xtoro is an ear drop, so this mainly matters with oral quinolones. Check with your pharmacist about your exact product.

References
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Pletz MW, Petzold P, Allen A, et al. Effect of calcium carbonate on bioavailability of orally administered gemifloxacin. Antimicrob Agents Chemother 2003;47:2158-60.. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Dolomite Also Interacts With Other Medications

Dolomite has 56 major, 71 moderate known drug interactions in our database — the Finafloxacin one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Dolomite

Covers the 2,830 medications we’ve checked against Dolomite. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Finafloxacin

This page covers Dolomite only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Finafloxacin page lists 54 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Bacillus Coagulans (moderate), Bacillus Subtilis (moderate), Bifidobacterium Animalis Subsp. Lactis (moderate), Bifidobacterium Bifidum (moderate) and Bifidobacterium Breve (moderate).

By severity: 47 moderate · 7 minor.

From our pharmacist’s overview on the Finafloxacin page

“The clearest snag on the supplement list for finafloxacin (Xtoro), a quinolone antibiotic ear drop for outer ear infections, is minerals. Calcium and iron can bind quinolone drugs in the gut and cut how much gets absorbed, so those doses belong hours apart.”

Reviewed by 2 · Jul 18, 2026

Open the Finafloxacin interaction page

One more smart check

Taking Dolomite as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Dolomite, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Dolomite. Your product may carry other ingredients that interact with Finafloxacin too, on top of Dolomite — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Dolomite and Finafloxacin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dolomite
Steady interest

#793 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Finafloxacin
Steady interest

#2,052 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Dolomite

What is Dolomite?

Dolomite
  • Source of calcium
  • Source of magnesium
  • Bone health support
  • Antacid for heartburn
  • Mineral supplementation

Dolomite is a natural mineral that provides both calcium and magnesium. However, many health authorities advise against using it because dolomite products have been found to contain heavy metals like lead, arsenic, and mercury, and safer, better-tested calcium and magnesium supplements are widely available.

Read the full Dolomite monograph & all interactions
Keep checking

Other Drugs & Dolomite

Browse every other medication we’ve checked against Dolomite — both the ones with a known interaction and the ones without. Select any drug for the full detail.

56Major
71Moderate
0Minor
2,702No known interaction
Major

56 interactions

Moderate

71 interactions

Showing 60 of 71 moderate interactions — see all 71 on the Dolomite page.

No interaction 2,702 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Dolomite and Finafloxacin Together: Common Questions

Can you take Dolomite with Finafloxacin?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Dolomite and Finafloxacin interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Finafloxacin and Dolomite?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.