Jequirity - Mayzent (Siponimod) Interaction
Herbal: Jequirity
Also Known As: Abrus precatorius, Bead Vine, Black-Eyed Susan, Chanothi, Chashami -Khurosa, Chunhali, Crab's Eye, Ghunchi, Gunchi, Gundumani, Gunja, Guruginia, Gurugunii, Indian Bead, Jequirity Seed, Kunch, Kundumani, Pater Noster, Pois Rouge, Prayer Beads, Prayer Head, Precatory Bean
Drug: Siponimod
Brand names:
Mayzent

Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Siponimod is classified as belonging to the following category: Cytochrome P450 3A4 (Cyp3A4) Substrates
In vitro research shows that jequirity extract inhibits CYP3A4 enzymes. Theoretically, taking jequirity may inhibit the metabolism of CYP3A4 substrates.
Interaction Rating
Likelihood of Occurrence
UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
References
- Ai C, Miao X, Wang L, He J. Discovery and Activity Evaluation of the Inhibitory Effect of Four Kinds Traditional Chinese Medicine Extracts on the CYP3A4 Enzyme. Comb Chem High Throughput Screen 2022.
Jequirity Overview

Siponimod Overview
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Siponimod is used to prevent episodes of symptoms and slow the worsening of disability in adults with relapsing-remitting forms (course of disease where symptoms flare up from time to time) of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control). Siponimod is in a class of medications called sphingosine l-phosphate receptor modulators. It works by decreasing the action of immune cells that may cause nerve damage.
Jequirity - More Interactions
Jequirity interacts with 787 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.