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Dietary supplement

Moringa Pure 4X Extract Ingredients & Drug Interactions

by Shape Organics

Moringa Pure 4X Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Moringa Pure 4X Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Moringa Pure 4X Extract is a dietary supplement by Shape Organics with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement, blood sugar support, cholesterol support.Based on those ingredients, 869 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Moringa oleifera extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Moringa Pure 4X Extract by Shape Organics

Ask about any prescription or over-the-counter medication and we check it for interactions with Moringa Pure 4X Extract by Shape Organics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Moringa Pure 4X Extract by Shape Organics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: moringa oleifera extract. Moringa is a plant extract traditionally used in various health contexts, though the science behind most of those uses isn't solid yet.

The capsule also holds rice extract and a vegetarian capsule shell as inactive ingredients — those are just fillers and the delivery method, not the active part.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Moringa's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: blood sugar, immune function, joint health, stress.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Hyperlipidemia, Inflammation, Cognitive function, Anxiety.
  • The closest evidence on file: Moringa is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Moringa is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia, Impaired glucose tolerance (prediabetes).

The evidence for moringa's effectiveness isn't established in our data. The product's ingredient shows insufficient reliable evidence for iron deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, and high cholesterol.

That means human trials either haven't been done, haven't been thorough, or have given mixed results — not that moringa doesn't work, just that we don't have solid proof yet.

The evidence, ingredient by ingredient Moringa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Moringa leaf appears generally well tolerated as food, though high-quality safety data are limited. The most common side effect is transient diarrhea — one small trial found it in about 25% of people taking 8 grams daily.

Rare serious side effects include allergic reactions (including severe ones) and a skin-and-mucous-membrane reaction called Stevens-Johnson syndrome, though both are uncommon. Avoid medicinal amounts; the root and bark may stimulate the uterus, and safety data are lacking.

If you're breastfeeding, the evidence is mixed — moringa was traditionally used to boost milk supply, but safety hasn't been well studied, so talk it over with your doctor or pharmacist.

Side effects, ingredient by ingredient Moringa

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Moringa.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 870 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take any CYP3A4 substrate drugs (a large group covering heart, blood pressure, cholesterol, cancer, and other medications — your pharmacist can look this up fast), levothyroxine or other thyroid replacements, P-glycoprotein substrate drugs, diabetes medications, or CYP1A2 substrate drugs. Even though some of these interactions are rated Minor, the sheer number of medications involved means it's worth a quick conversation with your own healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Moringa Pure 4X Extract might appeal to someone looking for a traditional plant supplement, but the science backing its use for most conditions is sparse. The bigger concern is interactions with common medications, especially those processed through CYP3A4 and thyroid hormone replacement.

Before you start, check your medications against the full list on this page and talk with your doctor or pharmacist — they can tell you whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Moringa Pure 4X Extract, straight from the product label.

Brand Shape Organics
Barcode (UPC) 852181008753
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 276686
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Moringa Pure 4X Extract by Shape Organics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
852181008753
IngredientAmount% DV
Moringa oleifera extract1200 mg--

Other ingredients: Rice extract, Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults take one capsule 2 times daily, or as directed by a healthcare professional.

Please combine with healthy diet & exercise to maximize the effectiveness of the active ingredients. Take with food for best absorption and bioavailability in the body.

Precautions

Caution: Please consult your healthcare professional before taking this supplement if you are taking any OTC and/or prescription medications for a health condition.

Store in a cool, dry place out of the reach of children.

Formula

Moringa Oleifera 4:1 extract

4:1 Moringa naturally contains high levels of antioxidants that will help you improve mood, energy, and healthy weight management.

Formulation

Use as part of a healthy diet to help maintain healthy blood sugar levels Boost proper immune function Helps maintain joint health and flexibility May contribute to a healthy brain Helps reduce stress and tension

Does not contain fillers, preservatives, stearates, laureates, sulfates. Free of egg, milk, peanut, shellfish, soy, and wheat.

Morniga 4x Is a pure potent super green with a wide-range of positive benefits.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice FDA inspected facility Made in the USA

Storage

Store in a cool, dry place out of the reach of children.

General Statements

Blessings!

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Moringa Pure 4X Extract by Shape Organics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Moringa Pure 4X Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Moringa Pure 4X Extract by Shape Organics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Moringa oleifera extract

Interacts with
869 drugs
1200 mg per serving

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....

Moringa oleifera extract monograph & interactions

Other (inactive) ingredients: Rice extract, Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Moringa Pure 4X Extract by Shape Organics Drug Interactions

Want to check YOUR meds against Moringa Pure 4X Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
869Drugs
717 Moderate 152 Minor

Ingredients driving the most interactions

Moringa oleifera extract 869

Individual Drug Interactions

The ingredients in Moringa Pure 4X Extract interact with 869 drugs. Click any drug to see the details.

1 of the 1 ingredient in Moringa Pure 4X Extract interact with drugs. Each result below shows which ingredient is responsible. Moringa oleifera extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Moringa Pure 4X Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Moringa oleifera extract6 drug types · 869 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Possible Evidence D
Levothyroxine (Synthroid, Others)

Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Nevirapine (Viramune)

Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Unlikely Evidence B
Moringa oleifera extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Moringa Pure 4X Extract, from the product label.

Shape Organics

See all Shape Organics products
Name
Shape Organics
City
Buffalo
State
WY
ZipCode
82834
Web Address
Shapeorganics.com
Pharmacist Counseling Corner

Moringa Pure 4X Extract by Shape Organics: Common Questions

Does Moringa Pure 4X Extract by Shape Organics interact with any medications?
Yes. Based on its ingredients, Moringa Pure 4X Extract has a known interaction with 869 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Moringa Pure 4X Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take moringa if I'm pregnant or breastfeeding?
Pregnancy data show moringa is possibly safe and also possibly unsafe — the evidence is mixed, so there isn't a clear answer. If you're pregnant, talk with your doctor or pharmacist about whether to use it. For breastfeeding, it's rated possibly safe, but safety hasn't been well studied even though it was traditionally used to boost milk supply — check with your own provider before starting.
What side effects might I get?
Diarrhea is the most common — about a quarter of people taking 8 grams daily in a trial experienced transient diarrhea. Rare serious effects include allergic reactions and a severe skin-and-mouth reaction called Stevens-Johnson syndrome, though these are uncommon.
Does moringa actually work for what it claims?
We don't have solid evidence yet. The ingredient shows insufficient reliable evidence for iron deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, and high cholesterol — meaning either trials haven't been done thoroughly or results have been mixed.
Is there anything in this that isn't the active ingredient?
Yes — rice extract and the vegetarian capsule material are inactive fillers and the delivery method. Moringa oleifera extract is the only active part.
How many medications could this interact with?
The interactions documented for moringa span 870 individual medications, mostly through the CYP3A4 enzyme system, which processes a huge range of drugs. That's why it's so important to check your specific medications before starting.
Is moringa safe to use with my medications?
We can't answer that as a yes or no — it depends entirely on which drugs you take. Use the medication checker on this page to see if any of yours are on the interaction list, then talk it over with your doctor or pharmacist. They know your complete picture and can give you personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Moringa Pure 4X Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Moringa Pure 4X Extract label
Go deeper

The Full Monographs Behind Moringa Pure 4X Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Moringa

Interacts with 869 drugs

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common. Early research hints at possible benefi...

Read the full Moringa monograph →
Sources

Sources & How We Checked

Moringa Pure 4X Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Moringa 23 references
  1. Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
  2. Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000;41:319-23. PubMed
  3. Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
  4. Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
  5. Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
  6. Monera TG, Wolfe AR, Maponga CC, et al. Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2008;2:379-83.
  7. Estrella M, Mantaring J, David G, Taup M. A double blind, randomised controlled trial on the use of malunggay (Moringa oleifera) for augmentation of the volume of breastmilk among non-nursing mothers of preterm infants. Philipp J Pediatr 2000;49:3-6.
  8. Morton, J. F. The Horseradish Tree, Moringa Pterygosperma (Moringaceae) - a boon to arid lands? Economic Botany 1991;45:318-333. DOI
  9. Espinosa-Kuo CL. A Randomized Controlled Trial on the Use of Malunggay (Moringa oleifera) for Augmentation of the Volume of Breastmilk Among Mothers of Term Infants. Filipino Family Physician. 2005;43(1):26-33.
  10. King JS, Raguindin PFN, Dans LF. Moringa oleifera (Malunggay) as a Galactagogue for Breastfeeding Mothers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Philipp J Pediatr 2013;61(2):34-42.
  11. Singh D, Choudhury S, Singh TU, Garg SK. Pharmacodynamics of uterotonic effect of Moringa oleifera flowers extract. J Vet Pharmcol Toxicol 2008;7(1-2):12-15.
  12. William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
  13. Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017;14:12. doi: 10.1186/s1 PubMed
  14. Witharana EWRA, Wijetunga WMGASTB, Wijesinghe SKJ. Stevens - Johnson syndrome (SJS) following murunga leaf (Moringa oleifera) consumption. Ceylon Med J 2018;63(4):188-9.
  15. Nur R, Demak IPK, Radhiah S, Rusydi M, Mantao E, Larasati RD. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women. Enferm Clin. 2020;30 Suppl 4:79-82. DOI
  16. Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M
  17. Sumiaty, Tahir A, Burhanuddin B, Nurhaedar J, Veni H. The effect of moringa leaves on pregnancy on growth and morbidity of 6-11 month. Enferm Clin. 2020;30 Suppl 4:104-108. DOI
  18. Ulmy MN, Tahir A, Arsunan AA, Burhanuddin B, Veni H. Effect of moringa leaves during pregnancy on growth and morbidity in 0-5 months. Enferm Clin. 2020;30 Suppl 4:61-65. DOI
  19. Amaeze O, Marques ES, Wei W, et al. Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction. Curr Drug Metab. 2021;22(14):1103-1113. PubMed
  20. Ebhohon E, Miller D. Moringa Oleifera leaf extract induced pulmonary embolism-a case report. Int J Emerg Med 2022;15(1):16. PubMed
  21. Basri H, Hadju V, Zulkifli A, Syam A, Indriasari R. Effect of Moringa oleifera supplementation during pregnancy on the prevention of stunted growth in children between the ages of 36 to 42 months. J Public Health Res 2021;10(2):2207.
  22. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  23. Amsler E, Mahevas T, Soria A, Barbaud A. Fixed food eruption to Moringa oleifera. Contact Dermatitis 2023;89(4):301-302.

See these in context on the Moringa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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