Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

NDF Detox Ingredients & Drug Interactions

by Bioray Clinical

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

NDF Detox is a dietary supplement by Bioray Clinical with 2 active ingredients. Its ingredients are commonly taken for digestive health and regularity, antibiotic-associated diarrhea, irritable bowel syndrome (ibs).Based on those ingredients, 899 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorella, Micronized, CytoFlora Probiotics Lystates. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of NDF Detox by Bioray Clinical

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 13 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (96 mg) without saying how much of each component you get.
  • “CytoFlora Probiotics Lystates” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

NDF Detox contains 13 ingredients total, including seven different species of live Lactobacillus bacteria (acidophilus, salivarius, plantarum, paracasei, casei, helveticus, rhamnosus, and reuteri), three Bifidobacterium species (longum infantis, longum, and bifidum), plus cilantro (coriander), chlorella (a green algae), and a blend called CytoFlora Probiotics Lystates. The inactive ingredients are deionized water and grain alcohol.

The probiotics are meant to support your gut bacteria balance, while cilantro and chlorella are included as additional detox-supporting botanicals. This is a liquid supplement, so it can be easier to dose than pills or capsules.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: improve immune function, memory, energy and sleep.
  • We looked for evidence on: Age-related cognitive decline, Cognitive function, Common cold, Diarrhea, Fatigue, Generalized anxiety disorder (GAD) — and 3 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Coriander is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Diarrhea.
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD), Radiation-induced diarrhea, Rotaviral diarrhea, Travelers' diarrhea.

The evidence for this product's overall effectiveness as a detox isn't covered in our data. For individual ingredients, Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), antibiotic-related diarrhea, bacterial vaginosis, and Helicobacter pylori infection.

Bifidobacterium bifidum is possibly effective for IBS and respiratory tract infections. For most other uses listed — cilantro for diabetes and digestive issues, chlorella for various conditions, and the other probiotics — the evidence we hold is insufficient to rate their effectiveness.

Talk to your pharmacist about what this product is meant to do for your situation.

The evidence, ingredient by ingredient Probiotics Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The probiotics in this product are generally well tolerated in healthy adults and children, though people who are seriously ill or immune-compromised should use caution and check with their doctor first. Rare side effects from probiotics include gastrointestinal discomfort, bloating, flatulence, and diarrhea — usually mild and temporary.

Very rarely, live probiotic bacteria have caused serious infections (bacteremia or sepsis) in critically ill patients, though these cases are uncommon. Cilantro is safe in normal food amounts but lacks safety data at medicinal doses; concentrated doses or essential oil should be avoided without medical advice.

Chlorella may cause allergic reactions, abdominal cramping, constipation, diarrhea, fatigue, nausea, and photosensitivity, especially in the first two weeks. Anaphylaxis (a severe allergic reaction) is rare but has been reported with both cilantro and chlorella.

Chlorella also carries quality and purity concerns across different products.

Side effects, ingredient by ingredient Probiotics Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Coriander, Lactobacillus Acidophilus, Chlorella, Bifidobacterium Bifidum, Bifidobacterium Longum, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this product if you're on any of the following: antibiotic drugs (space out the doses), antidiabetes drugs like metformin or insulin (cilantro may lower blood sugar), antihypertensive (blood pressure) drugs (cilantro may lower it further), warfarin or other blood thinners (chlorella contains vitamin K), CNS depressants (sedatives, anti-anxiety meds, sleep aids), or photosensitizing drugs (cilantro and chlorella may increase sun sensitivity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a multi-strain probiotic supplement with herbal add-ons. It may help if you're interested in gut health support, but the evidence for its detox claims specifically isn't established in our data.

If you take antibiotics, blood pressure or diabetes medication, blood thinners like warfarin, sedatives, or drugs that increase sun sensitivity, you need to check with your pharmacist first — several ingredients interact with these. People who are seriously ill or have weakened immune systems should talk to their doctor before starting probiotics.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 13 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NDF Detox, straight from the product label.

Brand Bioray Clinical
Net contents 30 mL; 1 Fluid Ounce(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334003
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Children (All), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NDF Detox by Bioray Clinical, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s), 1 Drop(s), 1 Drop(s), 1 Drop(s)
Maximum serving Sizes:
78 Drop(s), 52 Drop(s), 26 Drop(s), 13 Drop(s)
Servings per container
18
IngredientAmount% DV
Proprietary Blend96 mg--
Lactobacillus acidophilus0 NP--
Lactobacillus salivarius0 NP--
Bifidobacterium longum infantis0 NP--
Lactobacillus plantarum0 NP--
Bifidobacterium longum0 NP--
Bifidobacterium bifidum0 NP--
Lactobacillus paracasei0 NP--
Lactobacillus casei0 NP--
Lactobacillus helveticus0 NP--
Lactobacillus rhamnosus0 NP--
Lactobacillus reuteri0 NP--
Cilantro0 NP--
CytoFlora Probiotics Lystates0 NP--
Chlorella, Micronized0 NP--

Other ingredients: Water, Deionized, Grain Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

This remedy will... Improve immune function Boot memory & eliminate brain fog Increase vitality, energy, focus, & concentration Promote restful sleep & balanced moods

Heavy metal cleanser For stronger system Naturopathic herbal drops

Our probiotics are hypoallergenic, in a dairy-free rice base.

Our probiotics are hypoallergenic, in a dairy-free rice base.

Suggested/Recommended/Usage/Directions

How to take: Adults: Start with 3-6 drops in water or juice. Increase by 6 drops per day to optimal dose. Children & Sensitive individuals: Start with 1 drop in water or juice. Increase intake by 3 drops every 3-4 days or as tolerated to optimal dose. Shake well before each use. Optimal Dose by Weight: Under 40 lbs 0.5 ml (13 drops) 2x a day 40-75 lbs 1 ml (26 drops) 2x a day 76-150 lbs 2 ml (52 drops) 2x a day Over 150 lbs 3 ml (78 drops) 2x a day

Precautions

If pregnant or nursing, consult with a healthcare professional.

Keep out of reach of children.

FDA Statement of Identity

Dietary Supplement

General Statements

30 mL (1 fl oz) Bottle

Storage

Store at room temperature. No refrigeration needed.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

NDF Detox by Bioray Clinical label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in NDF Detox by Bioray Clinical

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container18 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

96 mg per serving

Other (inactive) ingredients: Water, Deionized, Grain Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

NDF Detox by Bioray Clinical Drug Interactions

Want to check YOUR meds against NDF Detox?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
899Drugs
862 Moderate 37 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in NDF Detox with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorella, Micronized2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D

CytoFlora Probiotics Lystates2 drug types · 222 drugs

Antibiotic Drugs

Theoretically, taking antibiotic drugs with certain probiotics might decrease the effectiveness of probiotics.
Many probiotics are bacteria. Since these preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of sensitive organisms. Human research shows that taking probiotic concurrently with antibiotic treatment does not affect the diversity of the gut microbiome compared with antibiotic treatment in the absence of probiotics. Tell patients to separate administration of antibiotics and these preparations by at least two hours.

Likelihood Probable Evidence D
Antifungals

Theoretically, taking antifungals with certain probiotics might decrease the effectiveness of probiotics.
Some probiotics such as Saccharomyces boulardii are fungi. Therefore, simultaneously taking antifungals might kill a significant number of these organisms.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for NDF Detox, from the product label.

Bioray Clinical

See all Bioray Clinical products
Name
BioRay Inc.
City
Irvine
State
CA
ZipCode
92618
Phone Number
(888) 635-9582
Web Address
bioray.com
Pharmacist Counseling Corner

NDF Detox by Bioray Clinical: Common Questions

Does NDF Detox by Bioray Clinical interact with any medications?
Yes. Based on its ingredients, NDF Detox has a known interaction with 899 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NDF Detox contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while on antibiotics?
The probiotics in this product might not work well if you take antibiotics at the same time, because the antibiotics could kill the live bacteria. Space them out — take your antibiotic a few hours apart from this supplement, and definitely mention it to your doctor or pharmacist for the best timing for your specific medication.
Is this safe during pregnancy?
Some of the probiotics (Lactobacillus acidophilus, Bifidobacterium longum, and Bifidobacterium bifidum) are rated possibly safe in pregnancy, but cilantro and chlorella have no pregnancy safety data on file. Talk to your doctor or midwife before starting any supplement during pregnancy — they know your full health picture.
What are the probiotics actually for?
Probiotics aim to support your gut bacteria balance. Some of these strains have possibly effective evidence for irritable bowel syndrome, antibiotic-related diarrhea, and a few other digestive or immune concerns, but the data varies by species. The product as a whole isn't marketed for a single specific condition in our data.
What if I'm allergic to shellfish or seafood — is this safe?
We don't have allergy cross-reactivity data for these ingredients in our product facts, so I can't tell you yes or no. If you have a shellfish allergy and are concerned about cilantro or chlorella, ask your pharmacist or allergist first.
Can I breastfeed while taking this?
Lactation safety data are limited or missing for most of these ingredients. One Bifidobacterium species notes to check with your doctor before using while breastfeeding. It's best to talk to your doctor or pharmacist — they can weigh the benefits and any risks for your situation.
What side effects might I notice?
Probiotics sometimes cause mild bloating, gas, or diarrhea, especially in the first week or two. Chlorella may cause nausea, cramping, or constipation initially. Cilantro is usually well tolerated in food amounts. Anaphylaxis (severe allergic reaction) is rare but possible with both cilantro and chlorella. Stop and call your doctor or pharmacist if you notice swelling, difficulty breathing, or severe reaction.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NDF Detox is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NDF Detox label
Sources

Sources & How We Checked

NDF Detox's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 147 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Coriander 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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