SAM-e Complete 400 mg By Nature Made Overview & Drug Interactions
Check For Interactions With SAM-e Complete 400 mg
Supplement: SAM-e Complete 400 mg by Nature Made
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
Protein
Ingredient Group | Protein (unspecified) |
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Category | protein |
SAM-e
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding SameIngredient Group | SAMe |
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Category | non-nutrient/non-botanical |
Drugs that interact with SAM-e Complete 400 mg by Nature Made
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
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Minimum serving Sizes: |
1 Tablet(s)
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Maximum serving Sizes: |
1 Tablet(s)
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UPC/BARCODE | 031604011635 |
Other Ingredients: |
S-Adenosylmethionine Tosylate Disulfate
Cellulose Gel
Methacrylic Acid Copolymer
Stearic Acid
Silicon Dioxide
Triethyl Citrate
Magnesium Stearate
Color added
Forms
Mannitol
Sodium Starch Glycolate
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Label Statments:
Suggested/Recommended/Usage/Directions |
- Suggested use: Start with 1 tablet per day. For easier swallowing, take with water before and during ingestion. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal.
If benefits are not achieved within two weeks, you may require a higher level of supplementation.
To determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1600mg/day) until benefits are achieved.
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General Statements |
- SAM-e is a moisture sensitive product. That is why at Nature Made, we use foil blister packaging to ensure that each tablet of our SAM-e Complete is fresh and safe when you take it.
- Helps support
A health mood & joint comfort
Clinically studied ingredient
Restores a healthy mood in as little as 7-14 days
- When your emotions are healthy & balanced, you feel like yourself. However, sometimes emotions can get out of balance, causing you to feel moody.
This imbalance can be associated with low levels of SAM-e (S-adenosylmethionine), a naturally occurring molecule produced by the body. SAM-e levels can run low due to various factors such as diet and aging.
Mood improvement
Days
Replenish your SAM-e levels and feel the difference in as little as 7-14 days when taken daily.
Helps support joint comfort
Nature Made SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue.
Nature Made St. John's Wort is the #1 Pharmacist Recommended Mood Health supplement followed by Nature Made SAM-e based on the U.S. News & World Report - Pharmacy Times Survey
Complete because studies have shown that SAM-e helps support a healthy mood & joint comfort
- Restores a healthy mood in as little as 7-14 days when taken daily
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Precautions |
- Foil blister pack ensures safety and freshness. Do not use if temper evident printed foil seal over tablets is broken.
- Store in a cool, dry place, out of reach of children.
- Caution: People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision.
- If you are pregnant or nursing, or taking prescription medications, including antidepressants, consult your doctor before using this product.
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Storage |
- Store in a cool, dry place, out of reach of children.
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FDA Statement of Identity |
- Dietary Supplement
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FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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General |
- List No: 1163 P202 Cat: A852 1A232 ITEM # 590598
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Brand IP Statement(s) |
- SAM-e Complete tablets are made to Nature Made's guaranteed purity and potency standards.
- From the #1 pharmacist recommended mood health supplement brand, Nature Made SAM-e helps support a healthy mood.
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Formulation |
- This product is gluten free.
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Brand Information
See all products by this brand
Distributed by: | |
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Name | Nature Made Nutritional Products |
City | Mission Hills |
State | CA |
Country | U.S.A. |
ZipCode | 91346-9606 |
Phone Number | 1-800-276-2878 |
Web Address | www.NatureMade.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.