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Dietary supplement

Slippery Elm Select Ingredients & Drug Interactions

by Moss Nutrition

Slippery Elm Select label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Slippery Elm Select against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Slippery Elm Select is a dietary supplement by Moss Nutrition with 2 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,161 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm, Powder, Boswellia serrata Gum Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Slippery Elm Select by Moss Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm Select by Moss Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Slippery Elm Select by Moss Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains two active ingredients: slippery elm and Boswellia serrata gum extract. Slippery elm is the inner bark of the slippery elm tree; it's a demulcent, meaning it forms a soothing, protective coating in your digestive tract.

Boswellia serrata is a resin from a tree native to India and Africa, traditionally used to support joint comfort and inflammation response. The product has no other inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and joint comfort.
  • We looked for evidence on: Asthma, Constipation, Cough, Crohn disease, Diarrhea, Inflammatory bowel disease (IBD) — and 4 related terms.
  • The strongest evidence on file: Boswellia Serrata is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Boswellia Serrata is rated "Insufficient Reliable Evidence To Rate" for Asthma, Crohn disease, Diarrhea, Irritable bowel syndrome (IBS), and more.

For slippery elm, the evidence isn't established in our data — the research is insufficient to say whether it works for cough, constipation, diarrhea, inflammatory bowel disease, or cancer. Boswellia serrata shows possibly effective evidence for osteoarthritis, meaning some research supports its use for joint pain and stiffness.

For its other uses — hay fever, Alzheimer disease, asthma, and cluster headache — the evidence in our data is insufficient to rate it.

The evidence, ingredient by ingredient Slippery Elm Boswellia Serrata

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, though high-quality safety data are limited. Some sources advise caution during pregnancy because safety data are insufficient, and there's too little information on breastfeeding safety.

Boswellia serrata is also generally well tolerated in the short term, but the safety data advise against it during pregnancy; breastfeeding safety is unknown, so it should be avoided while nursing. The most common side effects from Boswellia are abdominal pain, diarrhea, headache, heartburn, itching, nausea, dizziness, and vertigo.

In rare cases, large amounts of Boswellia gum resin have caused bezoar formation (a ball of material in your stomach). Slippery elm pollen is an allergen, and topical contact with slippery elm can cause contact dermatitis or hives in sensitive people.

Side effects, ingredient by ingredient Slippery Elm Boswellia Serrata

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Boswellia Serrata, Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 2,162 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any medications your liver processes, especially blood thinners, heart drugs, antidepressants, and seizure medications — Boswellia serrata inhibits several major drug-metabolizing enzymes. Also check if you take immunosuppressants, since Boswellia may alter how they work.

And if you take any oral medication where timing and absorption matter, run it through the checker, because slippery elm may slow how much of it your body absorbs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have osteoarthritis, Boswellia may be worth discussing with your pharmacist — it has some evidence behind it. If you're pregnant or breastfeeding, check with your doctor or pharmacist first; Boswellia is best avoided, and slippery elm safety data are thin.

Most important: because these ingredients may change how your body processes many medications, check your exact drug list with the tool below before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Slippery Elm Select, straight from the product label.

Brand Moss Nutrition
Barcode (UPC) M134
Net contents 166 Gram(s); 5.8 Ounce(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 329184
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Slippery Elm Select by Moss Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3.7 Gram(s)
Maximum serving Sizes:
3.7 Gram(s)
Servings per container
45
UPC/BARCODE
M134
IngredientAmount% DV
Slippery Elm, Powder2590 mg--
Boswellia serrata Gum Extract1110 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 1 Scoop per day or as directed by your healthcare professional. Either sprinkle on food, add to shake, or mix with water or juice, allow to thicken for 15 minutes & drink as a slurry. May be taken in divided doses. Contents may settle. Stir gently prior to use.

Precautions

Warning: If you are taking medication, have a medical condition or an upcoming medical procedure, or are pregnant or nursing, consult a physician before using.

If adverse reactions occur, discontinue use & consult your healthcare practitioner

Keep out of reach of children.

Formula

Slippery Elm Select With standardized Boswellia extract

FDA Statement of Identity

Dietary Supplement

Formulation

Does not contain gluten.

Storage

Store sealed in a cool, dry place.

Brand IP Statement(s)

Moss Nutrition professional supplements est. 1991

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Slippery Elm Select by Moss Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Slippery Elm Select label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Slippery Elm Select by Moss Nutrition

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3.7 Gram(s) Dosage formPowder Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Slippery Elm, Powder

Interacts with
2,022 drugs
2590 mg per serving

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...

Slippery Elm, Powder monograph & interactions

Boswellia serrata Gum Extract

Interacts with
952 drugs
1110 mg per serving Form: Boswellic Acids

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoart...

Boswellia serrata Gum Extract monograph & interactions
Interaction report

Slippery Elm Select by Moss Nutrition Drug Interactions

Want to check YOUR meds against Slippery Elm Select?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,161Drugs
2,161 Moderate

Ingredients driving the most interactions

Slippery Elm, Powder 2,022
Boswellia serrata Gum Extract 952

Individual Drug Interactions

The ingredients in Slippery Elm Select interact with 2,161 drugs. Click any drug to see the details.

2 of the 2 ingredients in Slippery Elm Select interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm, Powder Boswellia serrata Gum Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Slippery Elm Select with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm, Powder1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
Slippery Elm, Powder full monograph & interactions

Boswellia serrata Gum Extract6 drug types · 952 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.

Likelihood Possible Evidence D
Boswellia serrata Gum Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Slippery Elm Select, from the product label.

Moss Nutrition

See all Moss Nutrition products
Name
Moss Nutrition Products, Inc.
Street Address
380 Russell Street
City
Hadley
State
MA
ZipCode
01035
Phone Number
800-851-5444
Web Address
www.mossnutrition.com
Pharmacist Counseling Corner

Slippery Elm Select by Moss Nutrition: Common Questions

Does Slippery Elm Select by Moss Nutrition interact with any medications?
Yes. Based on its ingredients, Slippery Elm Select has a known interaction with 2,161 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Slippery Elm Select contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — Boswellia is best avoided in pregnancy and should not be used while breastfeeding because safety data are unknown. Slippery elm safety data in pregnancy are also insufficient, and there's too little information on breastfeeding. Talk to your doctor or pharmacist about whether this product is right for you.
What's slippery elm used for?
Slippery elm has been used traditionally to soothe the digestive tract, but the evidence in our data is insufficient to confirm it works for cough, constipation, diarrhea, inflammatory bowel disease, or cancer.
Does Boswellia serrata actually help with joint pain?
Boswellia serrata shows possibly effective evidence for osteoarthritis, meaning some research supports its use for joint pain and stiffness. For other conditions like hay fever or asthma, the evidence in our data is insufficient to rate it.
What are the side effects I should watch for?
The most common side effects from Boswellia are abdominal pain, diarrhea, headache, heartburn, nausea, and dizziness. Slippery elm pollen can trigger allergies, and topical contact may cause itching or hives if you're sensitive. In rare cases, very large amounts of Boswellia gum resin have caused a blockage in the stomach.
Will this slow down my other medications?
Yes — slippery elm's mucilage may theoretically slow how much of your oral drugs your body absorbs. Boswellia serrata can inhibit the liver enzymes that process many medications, which may raise their levels. That's why checking your exact drug list before starting is so important.
Is this product safe to use long-term?
Both ingredients are generally well tolerated for short-term use, but high-quality safety data are limited for slippery elm and the quality and dose vary widely between Boswellia products. Talk to your pharmacist about how long you plan to use it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Slippery Elm Select label
Go deeper

The Full Monographs Behind Slippery Elm Select’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph → Herb & supplement monograph

Boswellia Serrata

Interacts with 952 drugs

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoarthritis symptoms, but the overall evidenc...

Read the full Boswellia Serrata monograph →
Sources

Sources & How We Checked

Slippery Elm Select's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Boswellia Serrata 16 references
  1. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
  4. Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
  5. Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
  6. Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
  7. Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
  8. Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
  9. Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
  10. Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
  11. Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
  12. Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
  13. El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
  14. Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
  15. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  16. Valente IVB, Garcia D, Abbott A, et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat 2024;204(3):521-530. PubMed

See these in context on the Boswellia Serrata monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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