Interactions on record — worth a quick check against your medications. Based on 7 of 21 ingredients. Check your meds →
Dietary supplement

Tri Active Biotics Slimming Support Ingredients & Drug Interactions

by Essential Source

Tri Active Biotics Slimming Support label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tri Active Biotics Slimming Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tri Active Biotics Slimming Support is a dietary supplement by Essential Source with 21 active ingredients. Its ingredients are commonly taken for digestive health and regularity, infant colic and gut support, diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium breve BR-3, Lactobacillus acidophilus LA-2, Bifidobacterium bifidum BB-1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Tri Active Biotics Slimming Support by Essential Source

Ask about any prescription or over-the-counter medication and we check it for interactions with Tri Active Biotics Slimming Support by Essential Source — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Tri Active Biotics Slimming Support by Essential Source

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 21 active ingredients.
  • “Microencapsulated Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “FFe4 Fermented Fungal Enzyme Blend” is a proprietary blend — the label gives one combined amount (300 mg) without saying how much of each component you get.

Tri Active Biotics Slimming Support contains 21 active ingredients: multiple probiotic strains (live beneficial bacteria including several Lactobacillus and Bifidobacterium species, and Streptococcus thermophilus), fungal digestive enzymes (protease, amylase, lactase, and cellulase), and prebiotic support. The probiotics are designed to support gut health and digestion, while the enzymes help break down proteins, carbohydrates, lactose, and plant fibers so your body can absorb nutrients more efficiently.

The product also contains inactive ingredients—vegetable capsule, rice flour, rice extract, and ester of glycerol—that serve as the capsule shell and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: healthy weight management and metabolism support.
  • We looked for evidence on: obesity, metabolic syndrome.
  • The closest evidence on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome.
  • Also on file: Bifidobacterium Breve is rated "Insufficient Reliable Evidence To Rate" for Obesity, Metabolic syndrome.

The evidence on this product's individual ingredients varies. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Bifidobacterium bifidum is possibly effective for IBS and respiratory tract infections. Bifidobacterium longum and lactase lack sufficient evidence for most claims in our data, though lactase is effective for lactose intolerance.

For many of the other probiotic strains and enzymes, evidence isn't established in the data we hold, or the ratings are too preliminary to confidently recommend them for specific conditions. Talk with your doctor about whether this product is right for your particular health goals.

The evidence, ingredient by ingredient Bifidobacterium Breve Lactobacillus Acidophilus Bifidobacterium Bifidum Streptococcus Thermophilus Bifidobacterium Longum Proteolytic Enzymes (proteases) Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in healthy adults and children. Protease and Lactase can rarely cause allergic reactions or digestive upset; there's one historical report of lactase-induced contact dermatitis and allergic rhinoconjunctivitis in a worker exposed to powdered lactase.

Probiotics may cause bloating and flatulence when you first start, and in uncommon cases you might experience abdominal discomfort or gas. Since these are live organisms, very ill or severely immunocompromised people (including critically ill infants) should use probiotics only under medical guidance—rare cases of Bifidobacterium or Lactobacillus bacteremia (bacteria in the blood) have been reported in that population.

For pregnancy and breastfeeding: Protease safety hasn't been established in pregnancy, so it's best avoided unless prescribed; data on breastfeeding are limited, so ask your doctor. Lactase is likely safe in pregnancy.

Lactobacillus acidophilus is possibly safe in pregnancy, and data aren't on file for several other strains. Overall, check with your doctor or pharmacist before using this product during pregnancy or breastfeeding, since individual probiotic safety during these periods is still being studied.

Side effects, ingredient by ingredient Bifidobacterium Breve Lactobacillus Acidophilus Bifidobacterium Bifidum Streptococcus Thermophilus Bifidobacterium Longum Proteolytic Enzymes (proteases) Lactase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 7 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Breve, Bifidobacterium Bifidum, Bifidobacterium Longum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

The key medication type to watch is antibiotics. All four of the Bifidobacterium species and Lactobacillus acidophilus in this product carry a Moderate interaction with antibiotic drugs—simultaneously taking them may reduce the effectiveness of the probiotics.

Space out your doses: take your antibiotic at one time of day and the probiotic several hours later (or ask your doctor or pharmacist for the best timing for your specific antibiotic). For any other medications you take, use the search tool below to check whether they interact with the ingredients we could verify.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-strain probiotic and enzyme blend that may help with IBS, antibiotic-related diarrhea, or general digestive support if you tolerate probiotics well. If you're taking antibiotics, you'll want to space out doses to avoid reducing the probiotic's effectiveness.

If you have a weakened immune system, are very ill, or are pregnant or breastfeeding, talk with your doctor or pharmacist before starting—the safety profile in those groups needs individual assessment.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 21 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tri Active Biotics Slimming Support, straight from the product label.

Brand Essential Source
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 267371
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tri Active Biotics Slimming Support by Essential Source, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
IngredientAmount% DV
Lactobacillus rhamnosus GG0 NP--
Protease, Fungal0 NP--
Amylase, Fungal0 NP--
Lactobacillus plantarum LP-010 NP--
Bifidobacterium breve BR-30 NP--
Lactase, Fungal0 NP--
Microencapsulated Probiotic Blend0 NP--
Lactobacillus salivarius CRL-13280 NP--
FFe4 Fermented Fungal Enzyme Blend300 mg--
Prebiotic200 mg--
Lactobacillus reuteri LRE020 NP--
Bifidobacterium animalis lactis BS-010 NP--
Lactobacillus acidophilus LA-20 NP--
Lactobacillus plantarum LP-90 NP--
Lactobacillus rhamnosus LR-60 NP--
Lactobacillus casei LC-30 NP--
Bifidobacterium bifidum BB-10 NP--
Streptococcus thermophilus Y-80 NP--
Lactobacillus rhamnosus LR-50 NP--
Bifidobacterium longum BL-30 NP--
Bifidobacterium longum infantis BI020 NP--
Bifidobacterium lactis BA-50 NP--
Cellulase, Fungal0 NP--

Other ingredients: Vegetable Capsule, Rice Flour, Rice extract, Ester of Glycerol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Featuring Microencapsulated Bifidobacterium Breve BR03

Includes FFe4 Fermented Fungal Enzyme Blend

Formulation

Healthy weight management probiotics Boost metabolism Eliminate stored waste Assist digestion

Probiotics for weight loss? Many strains used in this superior blend have been studied and shown to assist in healthy weight management. Hundreds of studies have shown that specific probiotic strains have beneficial abilities which range from boosting metabolism, and processing carbohydrates into energy, to supporting healthy elimination and balancing hormones.

In fact... Bifidobacterium Breve BR03 was shown in studies to convert linoleic acid into CLA, which boosts metabolism.

Allergen: None

100% Non-GMO

Increase metabolism Reduce waistline Restore regularity 5 times more effective with microencapsulation Improve and balance digestion

Did you know... Fermented fungal enzymes, as used in FFe4, were shown to have a higher level of bioactivity, than normal digestive enzymes This product was manufactured in a GMP approved facility.

FDA Statement of Identity

Dietary Supplement

General Statements

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Storage

Suggested Use: Store this product in a cool dry place below 23.5 degrees C (75 degrees F). Keep in a place with relative humidity below 30% RH. Keep product away from direct light.

Store in a cool dry place.

Suggested/Recommended/Usage/Directions

Directions: Take one capsule daily. Best taken on empty stomach.

Seals/Symbols

GMP Good Manufacturing Practice Consistent Quality Made in USA

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to prevent, treat or cure any disease. The efficacy of this product has not been confirmed by clinical research, and traditional uses do not establish that this product will achieve any claimed result.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tri Active Biotics Slimming Support by Essential Source label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tri Active Biotics Slimming Support label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tri Active Biotics Slimming Support by Essential Source

These are the 21 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Microencapsulated Probiotic Blend

0 NP per serving

FFe4 Fermented Fungal Enzyme Blend

300 mg per serving

Prebiotic

200 mg per serving Form: organic VitaFiber-IMO

Other (inactive) ingredients: Vegetable Capsule, Rice Flour, Rice extract, Ester of Glycerol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tri Active Biotics Slimming Support by Essential Source Drug Interactions

Want to check YOUR meds against Tri Active Biotics Slimming Support?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bifidobacterium breve BR-3 182
Lactobacillus acidophilus LA-2 182
Bifidobacterium bifidum BB-1 182
Bifidobacterium longum BL-3 182

Individual Drug Interactions

The ingredients in Tri Active Biotics Slimming Support interact with 182 drugs. Click any drug to see the details.

4 of the 21 ingredients in Tri Active Biotics Slimming Support interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium breve BR-3 Lactobacillus acidophilus LA-2 Bifidobacterium bifidum BB-1 Bifidobacterium longum BL-3

Each ingredient & the kinds of drugs it affects

For each ingredient in Tri Active Biotics Slimming Support with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium breve BR-31 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium breve BR-3 full monograph & interactions

Lactobacillus acidophilus LA-21 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus LA-2 full monograph & interactions

Bifidobacterium bifidum BB-11 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium bifidum BB-1 full monograph & interactions

Bifidobacterium longum BL-31 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium longum BL-3 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tri Active Biotics Slimming Support, from the product label.

Essential Source

See all Essential Source products
Name
Essential Source, Inc.
Street Address
625 W. Deer Valley Road Suite 103-152
City
Phoenix
State
AZ
ZipCode
85027
Phone Number
(877) 879-9966
Web Address
www.EssentialSource.net
Pharmacist Counseling Corner

Tri Active Biotics Slimming Support by Essential Source: Common Questions

Does Tri Active Biotics Slimming Support by Essential Source interact with any medications?
Yes. Based on its ingredients, Tri Active Biotics Slimming Support has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tri Active Biotics Slimming Support contains 21 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this work if I'm taking an antibiotic?
Not at full strength if you take them at the same time. Antibiotics kill bacteria, including the live probiotics in this product. The solution is simple: take your antibiotic at one time of day and this product several hours apart—your doctor or pharmacist can tell you the best schedule for your specific antibiotic.
Can I take this while pregnant?
It depends on the ingredient. Lactase is likely safe, and Lactobacillus acidophilus is possibly safe. Protease hasn't been studied enough in pregnancy, so it's best avoided unless your doctor prescribes it. Check with your doctor or pharmacist before starting, since safety data are still limited for some strains.
What's the difference between the probiotics and enzymes in here?
The probiotics are live bacteria that colonize your gut and support digestive and immune health. The enzymes (protease, amylase, lactase, cellulase) break down different food components—proteins, carbs, lactose, and fiber—so your body can digest and absorb them more easily. Together they're meant to optimize digestion.
Can this cause bloating or gas?
Yes, a small number of people experience bloating or flatulence when starting probiotics, though these effects tend to settle as your gut adjusts. If it persists or is severe, talk with your doctor—it might mean the product isn't right for you, or your dose needs adjusting.
Is this safe for people with weak immune systems?
Probiotics are generally considered low-risk, but if your immune system is severely compromised—especially if you're critically ill, have an indwelling catheter, or are a preterm infant—use only under your doctor's direct guidance. Very rare cases of infection from probiotic bacteria have been reported in that population.
Does this help with weight loss or 'slimming'?
The product is branded for slimming support, but the evidence we hold doesn't establish that these specific strains or enzymes cause weight loss. Some probiotics like Lactobacillus acidophilus are possibly effective for IBS and digestive issues, which may indirectly support general wellness—talk with your doctor about realistic expectations.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tri Active Biotics Slimming Support is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tri Active Biotics Slimming Support label
Go deeper

The Full Monographs Behind Tri Active Biotics Slimming Support’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph → Herb & supplement monograph

Streptococcus Thermophilus

Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...

Read the full Streptococcus Thermophilus monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Lactase

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...

Read the full Lactase monograph →
Sources

Sources & How We Checked

Tri Active Biotics Slimming Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 77 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
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Streptococcus Thermophilus 21 references
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See these in context on the Streptococcus Thermophilus monograph →

Bifidobacterium Longum 21 references
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  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
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See these in context on the Bifidobacterium Longum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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