Drug & supplement interaction

Cajeput Oil + Larotrectinib

Larotrectinib brand name: Vitrakvi.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Cajeput Oil and Larotrectinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Cajeput Oil and Larotrectinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Larotrectinib and Cajeput Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cajeput Oil safety at a glance

Cajeput Oil overall Use caution Generally used topically or for inhalation in diluted form; it can irritate skin and should not be swallowed.
Pregnancy Avoid Safety has not been established, so it is best avoided during pregnancy.
Breastfeeding Avoid Not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Larotrectinib and Cajeput Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Larotrectinib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Larotrectinib is filed under 3 classifications — cytochrome p450 3a4 (cyp3a4) inhibitors, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Cajeput Oil has documented interactions with 2 drug classes — the most serious being antidiabetes drugs (moderate) and cytochrome p450 2d6 (cyp2d6) substrates (moderate) — and none of Larotrectinib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Cajeput Oil Does Interact With Other Medications

Cajeput Oil has 278 moderate known drug interactions in our database — Larotrectinib isn’t one of them. If you take anything else, check it against the full list below.

Moderate 278 No known interaction 2,552 (incl. Larotrectinib)
Taking anything else?

Check Another of Your Medications Against Cajeput Oil

Covers the 2,830 medications we’ve checked against Cajeput Oil. Pick one to open its full report.

What to actually watch for

What Larotrectinib’s Own FDA Label Lists

This is not an interaction — none of it involves Cajeput Oil. These are the most notable effects listed in the ADVERSE REACTIONS section of Larotrectinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Memory problems Worth acting on
  • Hallucinations Worth acting on
  • Confusion Worth acting on
  • A severe skin reaction Worth acting on
  • Chest pain Worth acting on
  • Low mood Worth acting on
  • Anemia Worth acting on
  • Shortness of breath Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on

Showing the 10 most notable of 38 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Larotrectinib. Read the label on DailyMed › Cajeput Oil’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cajeput Oil side to compare — that is a limit of the record, not a statement that Cajeput Oil has no side effects.

Everything else you take

See Every Supplement That Interacts With Larotrectinib

This page covers Cajeput Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Larotrectinib page lists 143 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 100 moderate · 40 minor.

From our pharmacist’s overview on the Larotrectinib page

“Nearly everything on this page interacts with larotrectinib (Vitrakvi) in one of two directions, raising or lowering how much of the drug ends up in your blood. Larotrectinib treats cancers driven by an NTRK gene fusion, and it is cleared by a liver enzyme called CYP3A4, so herbs that speed that enzyme up can drain the drug's effect wh…”

Reviewed by 2 · Jul 18, 2026

Open the Larotrectinib interaction page

How much people look this up

Where Cajeput Oil and Larotrectinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cajeput Oil
Top half

#567 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Larotrectinib
Steady interest

#1,751 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cajeput Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cajeput Oil and Larotrectinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cajeput Oil

What is Cajeput Oil?

Cajeput Oil
  • Muscle and joint aches
  • Cough and congestion
  • Minor skin irritation
  • Insect repellent
  • Aromatherapy

Cajeput oil is an aromatic essential oil traditionally used for aches, congestion, and minor skin complaints, but solid human evidence for these uses is limited. Like other essential oils, it should never be swallowed and should be diluted before applying to skin; consult a pharmacist or doctor before use, especially in children, pregnancy, or breastfeeding.

Melaleuca cajuputi · Myrtaceae · Essential oil distilled from the leaves and twigs · Essential oil, diluted topical rubs, inhalants/balms, aromatherapy blends

An interaction check asks whether these two react with each other — it does not ask whether Cajeput Oil is a good idea for someone in your situation. Here is what our Cajeput Oil record says about it on its own.

Cajeput Oil: dosing

There is no official, standardized dose for cajeput oil, and no proven safe amount for taking it internally. For topical or aromatherapy use, the general practice is to dilute a small amount of the essential oil in a carrier oil before applying to the skin.Because products differ in strength, follow the directions on the label and do not exceed them.

From our Cajeput Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cajeput Oil monograph & all interactions
Medication

About Larotrectinib

What Is Larotrectinib Used For?

Brand name: Vitrakvi

Vitrakvi is used to treat adult and pediatric patients with solid tumors that have a neurotrophic receptor tyrosine kinase (NTRK) gene fusion — a specific genetic alteration that can drive tumor growth. It is used when the tumor is metastatic (has spread) or when surgery to remove it would likely cause serious harm, and when there are no satisfactory alternative treatments or the cancer has continued to grow after prior treatment.

Patients must be selected for Vitrakvi therapy based on an FDA-approved test that confirms the NTRK gene fusion in their tumor. This approval is under the FDA's accelerated approval pathway, based on how many patients responded to treatment and how long those responses lasted. Continued approval may depend on results from follow-up clinical trials.

See full Larotrectinib drug information
Keep checking

Other Drugs & Cajeput Oil

Browse every other medication we’ve checked against Cajeput Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
278Moderate
0Minor
2,551No known interaction
278 Moderate 2,551 No interaction
Moderate

278 interactions

Showing 60 of 278 moderate interactions — see all 278 on the Cajeput Oil page.

No interaction 2,551 drugs checked — show the list

We also checked Cajeput Oil against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,551 medications checked with no known interaction — see the full Cajeput Oil list.

See the full Cajeput Oil interactions page
See every supplement checked against Larotrectinib, ranked by severity
Evidence & sources

Cajeput Oil References

The 2 references that drive our Cajeput Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Moharram, F. A., Marzouk, M. S., El Toumy, S. A., Ahmed, A. A., and Aboutabl, E. A. Polyphenols of Melaleuca quinquenervia leaves--pharmacological studies of grandinin. Phytother Res 2003;17(7):767-773.
  2. Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cajeput Oil and Larotrectinib Together: Common Questions

Is it safe to take Cajeput Oil with Larotrectinib?
We do not list a known interaction between Cajeput Oil and Larotrectinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Cajeput Oil and Larotrectinib combination checked?
Interactions in our licensed database are recorded against drug classes. Larotrectinib is filed under 3 classifications, and Cajeput Oil has documented interactions with 2 drug classes — none of Larotrectinib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Cajeput Oil interact with any other medications?
Yes. Cajeput Oil has 278 documented drug interactions in our database — Larotrectinib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Larotrectinib interact with any supplements?
Yes. Larotrectinib has documented interactions with 143 supplements in our database — Cajeput Oil is not one of them. The Larotrectinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Cajeput Oil monograph Uses, safety profile, and every drug interaction in one place Larotrectinib drug information The full plain-English guide to this medication Larotrectinib supplement interactions Every supplement checked against Larotrectinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Larotrectinib and Cajeput Oil?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.