Masterwort - Coricidin HBP Maximum Strength Flu (Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide) Interaction
Herbal: Masterwort
Also Known As: Heracleum sphondylium, Berce Commune, Berce Laineuse, Berce Très Grande, Cow Cabbage, Cow Parsnip, Hogweed, Imperatoria, Madnep, Radix Pimpinelle Franconiae, Woolly Parsnip, Youthwort
Drug: Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide
Brand names:
Coricidin HBP Maximum Strength Flu

Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Feb 09, 2025
Interaction Details
Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide is classified as belonging to the following category: Photosensitizing Drugs
The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effects.
Interaction Rating
Likelihood of Occurrence
ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
References
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Masterwort Overview

Masterwort - More Interactions
Masterwort interacts with 333 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.