Drug & supplement interaction

Masterwort + Insulin Aspart

Insulin Aspart brand name: Fiasp.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Masterwort and Insulin Aspart in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Masterwort and Insulin Aspart

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Insulin Aspart and Masterwort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Masterwort safety at a glance

Masterwort overall Use caution Limited safety data exist, and the plant can cause sun-triggered skin reactions.
Pregnancy Avoid Not enough safety information; best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Insulin Aspart and Masterwort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Insulin Aspart

Interactions in our licensed database are recorded against drug classes, not just single drug names. Insulin Aspart is filed under a single classification — antidiabetes drugs. Masterwort has documented interactions with 1 drug class — the most serious being photosensitizing drugs (moderate) — and none of Insulin Aspart’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Masterwort Does Interact With Other Medications

Masterwort has 335 moderate known drug interactions in our database — Insulin Aspart isn’t one of them. If you take anything else, check it against the full list below.

Moderate 335 No known interaction 2,495 (incl. Insulin Aspart)
Taking anything else?

Check Another of Your Medications Against Masterwort

Covers the 2,830 medications we’ve checked against Masterwort. Pick one to open its full report.

What to actually watch for

What Insulin Aspart’s Own FDA Label Lists

This is not an interaction — none of it involves Masterwort. These are the most notable effects listed in the ADVERSE REACTIONS section of Insulin Aspart’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • High blood sugar Worth acting on mentioned in 16.2% of FDA reports for Insulin Aspart
  • Low blood sugar Worth acting on mentioned in 5.2% of FDA reports for Insulin Aspart
  • Low potassium Worth acting on
  • Wheezing Worth acting on
  • Low mood Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on

Showing the 10 most notable of 22 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Insulin Aspart. Read the label on DailyMed › Where a percentage is shown, it is the share of 65,752 voluntary FDA FAERS reports for Insulin Aspart that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Masterwort’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Masterwort side to compare — that is a limit of the record, not a statement that Masterwort has no side effects.

Everything else you take

See Every Supplement That Interacts With Insulin Aspart

This page covers Masterwort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Insulin Aspart page lists 239 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate), Agaricus Mushroom (moderate) and Agmatine (moderate).

By severity: 1 major · 208 moderate · 30 minor.

From our pharmacist’s overview on the Insulin Aspart page

“Every one of the 239 supplements listed for insulin aspart (Fiasp) touches the same thing the drug exists to manage, blood sugar, so this list warrants genuine care rather than a quick skim. Most entries add to insulin's glucose-lowering effect, raising the risk of hypoglycemia, and with a rapid-acting mealtime insulin a low can become…”

Reviewed by 2 · Jul 18, 2026

Open the Insulin Aspart interaction page

How much people look this up

Where Masterwort and Insulin Aspart Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Masterwort
Top half

#661 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Insulin Aspart
Steady interest

#1,966 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Masterwort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Masterwort and Insulin Aspart records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Masterwort

What is Masterwort?

Masterwort
  • Digestive upset
  • Mild anxiety and tension
  • Skin complaints
  • Respiratory and cough relief
  • Traditional tonic

Masterwort (Heracleum sphondylium), a plant in the carrot family, has a long folk-medicine history for digestion, nerves, and skin. Modern scientific evidence to support these uses is very limited, and the plant can cause skin reactions to sunlight, so use it cautiously and talk with your pharmacist or doctor first.

Heracleum sphondylium · Apiaceae · Root, leaves, seeds, and aerial parts · Tea, tincture, dried herb, essential oil

An interaction check asks whether these two react with each other — it does not ask whether Masterwort is a good idea for someone in your situation. Here is what our Masterwort record says about it on its own.

Masterwort: dosing

There is no standardized, well-established dose for masterwort. Traditional preparations vary widely, and product strengths are not consistent.If you choose to use a commercial product, follow the directions on the label and do not exceed the suggested amount.

From our Masterwort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Masterwort monograph & all interactions
Medication

About Insulin Aspart (rDNA Origin) Injection

What Is Insulin Aspart (rDNA Origin) Injection Used For?

Brand name: Fiasp

Insulin aspart is used to improve blood sugar (glucose) control in people with diabetes mellitus. It is approved for both type 1 and type 2 diabetes in adults, and for diabetes mellitus in pediatric patients.

Insulin Aspart Protamine and Insulin Aspart Mix 70/30 is a pre-mixed product that combines a rapid-acting and an intermediate-acting insulin aspart. It is approved to improve blood sugar control in adult patients with diabetes mellitus. It is not recommended for treating diabetic ketoacidosis, and because its ratio of rapid-acting to intermediate-acting insulin is fixed, it does not allow for separate mealtime versus background dose adjustments.

Most-Reported Side Effects for Insulin Aspart

From FAERS, the FDA’s public side-effect reporting system (65,752 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Blood glucose increased 10,660 reports
Nausea 3,902 reports
Blood glucose decreased 3,409 reports
Fatigue 2,749 reports
Diarrhea 2,661 reports
See full Insulin Aspart (rDNA Origin) Injection drug information
Keep checking

Other Drugs & Masterwort

Browse every other medication we’ve checked against Masterwort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
335Moderate
0Minor
2,494No known interaction
335 Moderate 2,494 No interaction
Moderate

335 interactions

Showing 60 of 335 moderate interactions — see all 335 on the Masterwort page.

No interaction 2,494 drugs checked — show the list

We also checked Masterwort against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,494 medications checked with no known interaction — see the full Masterwort list.

See the full Masterwort interactions page
See every supplement checked against Insulin Aspart, ranked by severity
Evidence & sources

Masterwort References

The 1 references that drive our Masterwort monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Masterwort and Insulin Aspart Together: Common Questions

Is it safe to take Masterwort with Insulin Aspart?
We do not list a known interaction between Masterwort and Insulin Aspart. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Masterwort and Insulin Aspart combination checked?
Interactions in our licensed database are recorded against drug classes. Insulin Aspart is filed under 1 classification, and Masterwort has documented interactions with 1 drug class — none of Insulin Aspart's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Masterwort interact with any other medications?
Yes. Masterwort has 335 documented drug interactions in our database — Insulin Aspart is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Insulin Aspart interact with any supplements?
Yes. Insulin Aspart has documented interactions with 239 supplements in our database — Masterwort is not one of them. The Insulin Aspart interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Masterwort monograph Uses, safety profile, and every drug interaction in one place Insulin Aspart (rDNA Origin) Injection drug information The full plain-English guide to this medication Insulin Aspart supplement interactions Every supplement checked against Insulin Aspart, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Insulin Aspart and Masterwort?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.