Herb & supplement monograph

Strawberry Drug Interactions, Uses, Effectiveness, Safety & More

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Reviewed by licensed pharmacists Sourced from Natural Medicines

Strawberry Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Strawberry drug interaction appears low for most people. None of the listed interactions are rated major, and every one rests on lab or animal research rather than effects confirmed in people.

Interactions deserving the most attention

The combination most worth knowing about involves blood thinners such as warfarin, aspirin, and clopidogrel, because lab studies suggest strawberry's plant compounds might slow blood clotting, which could theoretically add to bleeding risk. Lab research also hints that strawberry could affect a transporter the body uses to move certain medications out of cells, which might raise levels of some drugs, including certain chemotherapy medications. Neither of these effects has been shown to happen in people eating strawberries.

What the rest of the list means

Although the number of listed medications is large, this comes almost entirely from those two theoretical mechanisms applied across many drugs, not from reported problems in people. Most of these combinations have never been shown to cause a meaningful change in how a medication works, so the length of the list says more about how many drugs share a common pathway than about real-world danger.

Check your medications against Strawberry

Based on HelloPharmacist’s Strawberry interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Strawberry

317 medications have a known interaction with Strawberry, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AbciximabReoPro› AbrocitinibCibinqo› AcalabrutinibCalquence› AcenocoumarolSintrom› Acetaminophen, AspirinGemnisyn› Acetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine› Acetaminophen, IbuprofenCombogesic› Acetylsalicylic AcidEntrophen› Afatinib DimaleateGilotrif› Alteplase, TpaActilyse, Activase› Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2› Aluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin› AlvimopanEntereg› AmbrisentanLetairis, Volibris› Amphotericin, TetracyclineMysteclin-F› AmprenavirAgenerase› Anacaulase-bcdbNexoBrid› AnagrelideAgrylin› AnisindioneMiradon› Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi› Antithrombin IiiThrombate III› ApixabanEliquis› ApomorphineAPO-go, APO-go Pen, APO-go PFS, Apokyn, Uprima› Apomorphine HydrochlorideKynmobi› ApremilastOtezla› ArgatrobanArgatroban› ArmodafinilNuvigil› AspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more› Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3› Aspirin, ButalbitalAxotal›
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Strawberry combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Strawberry affects

Every type of medication (drug category) Strawberry is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 2 drug categories Strawberry interacts with
Anticoagulant/antiplatelet DrugsP-glycoprotein Substrates
Anticoagulant/Antiplatelet Drugs

In vitro and animal research suggests that strawberry extract can inhibit platelet aggregation due to its phenolic content. Theoretically, strawberry might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux. Theoretically, strawberry might inhibit p-glycoprotein mediated drug efflux and potentially increase levels of drugs that are substrates of p-glycoprotein. Until more is known, strawberry should be used cautiously in people taking p-glycoprotein substrates.
Drugs that might be affected include some chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), protease inhibitors (amprenavir, indinavir, nelfinavir, saquinavir), H2 antagonists (cimetidine, ranitidine), some calcium channel blockers (diltiazem, verapamil), corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.

Likelihood Possible Evidence D
Monograph

Strawberry: Uses, Safety & Side Effects

The bottom line

Strawberry is a popular, nutrient-rich fruit that supplies vitamin C, fiber, and antioxidant plant compounds. Eating strawberries as part of a balanced diet is healthy for most people, but concentrated supplement forms have only limited research behind specific health claims. If you have allergies or take it as a supplement, check with your pharmacist or doctor.

Scientific name
Fragaria × ananassa
Family
Rosaceae
Part used
Fruit (berries); leaves are also used in some traditional preparations
Common forms
Fresh or frozen fruit, juice, powder, extracts, capsules, and leaf tea
People commonly use it for
  • General antioxidant support
  • Heart and blood vessel health
  • Blood sugar support
  • Skin and oral health
  • Source of vitamin C and fiber

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLikely safe

Strawberry fruit is widely eaten and considered safe for most people in normal food amounts.

PregnancyLikely Safe

When used orally in food amounts. There is insufficient reliable information available about the safety of strawberry for medicinal use in pregnancy a...

Read the full pregnancy detail
BreastfeedingLikely Safe

When used orally in food amounts. There is insufficient reliable information available about the safety of strawberry for medicinal use in pregnancy a...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Strawberry is the soft, red fruit of the Fragaria plant, a member of the rose family. The common garden strawberry grown around the world is a hybrid called Fragaria × ananassa. The plants are low-growing and are cultivated widely in temperate regions of North America, Europe, and Asia.

Most people enjoy strawberries simply as food. They are also sold as juices, dried powders, and concentrated extracts in capsules. The leaves are sometimes brewed into a mild tea in traditional herbal practice. Strawberries are valued because they are low in calories yet rich in vitamin C, fiber, and natural plant pigments called anthocyanins.

How it works

Strawberries contain several compounds that may explain their proposed benefits. Vitamin C supports the immune system and skin, while fiber aids digestion and may help with cholesterol and blood sugar. The red color comes from anthocyanins, a type of antioxidant. Strawberries also contain other polyphenols such as ellagic acid.

In laboratory and animal studies, these antioxidant compounds appear to reduce oxidative stress and inflammation. However, what happens in a test tube does not always translate to real benefits in people, and the amounts used in research may be higher than what a normal serving provides.

Effectiveness

Does Strawberry work?

Evidence overview · 13 uses evaluated
13 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Strawberry, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 13 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Cardiovascular disease (CVD)
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral strawberry for CVD, there is insufficient reliable information about the clinical effects of strawberry for this purpose.

Insufficient Reliable Evidence To Rate Colorectal cancer
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral strawberry for colorectal cancer, there is insufficient reliable information about the clinical effects of strawberry for this purpose.

Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral strawberry is beneficial in patients with diabetes.

Insufficient Reliable Evidence To Rate Diarrhea
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral strawberry for diarrhea, there is insufficient reliable information about the clinical effects of strawberry for this purpose.

Insufficient Reliable Evidence To Rate Gout
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral strawberry for gout, there is insufficient reliable information about the clinical effects of strawberry for this purpose.

Insufficient Reliable Evidence To Rate Hyperlipidemia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral strawberry is beneficial in patients with hyperlipidemia.

Insufficient Reliable Evidence To Rate Hypertension
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral strawberry is beneficial in patients with hypertension.

Insufficient Reliable Evidence To Rate Impaired glucose tolerance (prediabetes)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral strawberry is beneficial in patients with prediabetes.

Insufficient Reliable Evidence To Rate Kidney stones (nephrolithiasis)
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral strawberry for nephrolithiasis, there is insufficient reliable information about the clinical effects of strawberry for this purpose.

Insufficient Reliable Evidence To Rate Liver disease
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral strawberry for liver disease, there is insufficient reliable information about the clinical effects of strawberry for this purpose.

Insufficient Reliable Evidence To Rate Metabolic syndrome
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral strawberry for metabolic syndrome, there is insufficient reliable information about the clinical effects of strawberry for this purpose.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral strawberry is beneficial in patients with obesity.

Insufficient Reliable Evidence To Rate Osteoarthritis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral strawberry is beneficial in patients with osteoarthritis.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Strawberries are a common food and are considered safe for most people when eaten in normal amounts. The main concern is allergy. Strawberry allergy can cause hives, itching, swelling, or, rarely, a more serious reaction. People with pollen allergies sometimes notice mouth itching when eating fresh strawberries.

Concentrated supplements and extracts are far less studied than the fruit itself, so their long-term safety is unknown. Pregnancy and breastfeeding: eating strawberries as part of your normal diet is generally fine, but there is not enough information on concentrated strawberry supplements, so it is best to avoid them or check with your doctor first.

If you have a known allergy to strawberries or other berries, avoid them. Always talk to your pharmacist or doctor before starting any new supplement, especially if you have a health condition.

Side effects

For most people, strawberries cause few or no side effects when eaten as food. Possible issues include allergic reactions (itching, hives, swelling), mild digestive upset, or mouth tingling in sensitive people. Eating very large amounts may cause bloating or loose stools because of the fiber.

Serious allergic reactions (trouble breathing, throat swelling) are rare but are a medical emergency. Stop use and seek help right away if these occur.

Strawberry: Reported Adverse Effects

Documented safety reports on Strawberry from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Reports by condition
Allergic rhinitis (hay fever) Immunologic

Orally, consuming strawberry has been reported to cause allergic reactions, including oral allergy syndrome and skin reactions, in some patients.. Topically, strawberry has caused contact urticaria in one case report. Overall, allergy to strawberry appears to be rare.

  1. Cabrera-Freitag P, Bermejo Becerro A, Abreu Ramírez MG, et al. Allergy to strawberry in children from the Mediterranean area: is it really allergy? J Investig Allergol Clin Immunol 2020;30(4):283-5.
  2. Grattan CE, Harman RR. Contact urticaria to strawberry. Contact Dermatitis 1985;13:191-2. .
Nausea and vomiting Gastrointestinal
Tension headache Neurologic/CNS

Orally, taking freeze-dried strawberry powder 32 grams daily has been reported to cause a single case of headache in a clinical trial.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no official or standardized dose of strawberry for any health condition. As a food, a typical serving is about a cup of fresh strawberries, which fits easily into a healthy diet.

For supplements such as powders, extracts, or capsules, follow the directions on the product label, since concentrations vary widely between brands. Because dosing is not well established, it is wise to check with your pharmacist or doctor before using a concentrated product, especially if you are pregnant, breastfeeding, or managing a health condition.

Pregnancy & Breastfeeding
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 12 references that drive our Strawberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Wang SY, Jiao H. Scavenging capacity of berry crops on superoxide radicals, hydrogen peroxide, hydroxyl radicals, and singlet oxygen. J Agric Food Chem 2000;48:5677-84.. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Grattan CE, Harman RR. Contact urticaria to strawberry. Contact Dermatitis 1985;13:191-2. . PubMed
  4. Dutta-Roy, A. K., Crosbie, L., and Gordon, M. J. Effects of tomato extract on human platelet aggregation in vitro. Platelets. 2001;12(4):218-227. PubMed
  5. Van Gelder, J., Deferme, S., Naesens, L., De Clercq, E., van den, Mooter G., Kinget, R., and Augustijns, P. Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined este
  6. Deferme, S., Van Gelder, J., and Augustijns, P. Inhibitory effect of fruit extracts on P-glycoprotein-related efflux carriers: an in-vitro screening. J Pharm Pharmacol 2002;54(9):1213-1219.
  7. Naemura, A., Mitani, T., Ijiri, Y., Tamura, Y., Yamashita, T., Okimura, M., and Yamamoto, J. Anti-thrombotic effect of strawberries. Blood Coagul.Fibrinolysis 2005;16(7):501-509. PubMed
  8. Basu A, Betts NM, Nguyen A, Newman ED, Fu D, Lyons TJ. Freeze-dried strawberries lower serum cholesterol and lipid peroxidation in adults with abdominal adiposity and elevated serum lipids. J Nutr. 2014;144(6):830-7. PubMed
  9. Moazen S, Amani R, Homayouni Rad A, Shahbazian H, Ahmadi K, Taha Jalali M. Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: a randomized double-blind controlled trial. Ann Nutr PubMed
  10. Schell J, Scofield RH, Barrett JR, et al. Strawberries improve pain and inflammation in obese adults with radiographic evidence of knee osteoarthritis. Nutrients. 2017;9(9):949. PubMed
  11. Amani R, Moazen S, Shahbazian H, Ahmadi K, Jalali MT. Flavonoid-rich beverage effects on lipid profile and blood pressure in diabetic patients. World J Diabetes. 2014;5(6):962-8. PubMed
  12. Cabrera-Freitag P, Bermejo Becerro A, Abreu Ramírez MG, et al. Allergy to strawberry in children from the Mediterranean area: is it really allergy? J Investig Allergol Clin Immunol 2020;30(4):283-5. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Strawberry

3,591 products in our database contain Strawberry. Open any to see its full ingredient list and every drug interaction we check.

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Pharmacist Counseling Corner

Strawberry: Common Questions

What is Strawberry used for, and does it work?
People use Strawberry for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Strawberry interact with prescription medications?
Yes. We list 317 medications with a known interaction with Strawberry. Use the checker above to see how Strawberry interacts with a specific drug.
How are Strawberry interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Strawberry with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Strawberry interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Strawberry good for you?
Yes, strawberries are a healthy, low-calorie fruit rich in vitamin C, fiber, and antioxidants. They are a good addition to a balanced diet for most people.
Can Strawberry supplements treat or prevent disease?
There is not enough strong evidence to say that Strawberry supplements treat or prevent any specific disease. Eating the whole fruit as part of a healthy diet is the best-supported approach.
Are strawberries safe during pregnancy?
Eating strawberries as a normal part of your diet is generally considered fine during pregnancy. Concentrated Strawberry supplements are not well studied, so it is safer to avoid them unless your doctor approves.
Can strawberries cause allergies?
Yes. Some people are allergic to strawberries and may get itching, hives, or swelling. Rarely, reactions can be severe, so anyone with a known berry allergy should avoid them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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