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Dietary supplement

Astaxanthin 12 mg Ingredients & Drug Interactions

by Nature's Lab

Astaxanthin 12 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astaxanthin 12 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astaxanthin 12 mg is a dietary supplement by Nature's Lab with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AstaReal Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astaxanthin 12 mg by Nature's Lab

Ask about any prescription or over-the-counter medication and we check it for interactions with Astaxanthin 12 mg by Nature's Lab — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Astaxanthin 12 mg by Nature's Lab

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: AstaReal Astaxanthin, a naturally derived carotenoid (a pigment compound) at 12 mg per softgel. Astaxanthin is the bright red compound found in algae and seafood that gives salmon and shrimp their color.

The softgel itself is made from gelatin, extra virgin olive oil, glycerin, purified water, and mixed tocopherols (a form of vitamin E), which help preserve the astaxanthin.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Astaxanthin product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for astaxanthin isn't established in our data. We hold insufficient reliable evidence to rate it for age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

While astaxanthin is sold for these uses, we don't have the clinical trial data to back them up. Talk with your doctor about whether it might be worth trying for your specific concern.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects reported are abdominal pain, diarrhea, and red-colored stools (the red color comes from the astaxanthin itself and isn't dangerous).

At the 12 mg dose in this product, side effects are uncommon, though higher doses (around 40 mg daily) have caused severe stomach pain in a few people. There isn't enough safety data to know whether astaxanthin is safe in pregnancy or while breastfeeding, so the evidence-based recommendation is to avoid it during these times.

Talk with your doctor or pharmacist for personalized advice about your situation.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications before starting astaxanthin if you take drugs metabolized by CYP3A4 or CYP2B6 enzymes. This includes many statins, some blood pressure medications, immunosuppressants, and other commonly prescribed drugs — astaxanthin may lower their blood levels and reduce how well they work.

Your doctor or pharmacist can tell you whether any of your medications fall into these categories.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin 12 mg might appeal to you if you're interested in a carotenoid supplement and you're not pregnant or breastfeeding. The main thing to watch is whether you take medications broken down by your liver — especially common blood pressure and cholesterol drugs.

Before you start, run your exact medications through the checker on this page, then confirm with your own doctor or pharmacist that it's okay to combine them.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin 12 mg, straight from the product label.

Brand Nature's Lab
Barcode (UPC) 818014014353
Net contents 120 Easy-to-Swallow Softgel(s)
Market status On market
Date entered into DSLD Sep 24, 2019
DSLD ID 205289
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin 12 mg by Nature's Lab, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
818014014353
IngredientAmount% DV
Calories5 Calorie(s)--
Calories from Fat5 Calorie(s)--
Total Fat0.5 Gram(s)1%
AstaReal Astaxanthin12 mg--

Other ingredients: extra virgin Olive Oil, Gelatin, Glycerin, purified Water, Mixed Tocopherols

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Astaxanthin is a naturally occurring carotenoid that, due to its unique structure, performs an important role in cellular free radical protection. Astaxanthin is one of nature's most powerful antioxidants. Wild salmon, krill and shrimp derive their pink color from a diet rich in microalgae - a critical source of astaxanthin. Nature's Lab uses AstaReal Astaxanthin, one of the most studied brands as astaxanthin in the world. It is non-GMO, haematococcus pluvial micro algae and is farmed in the U.S.A. to ensure both quality and stability.

AstaReal Astaxanthin 12 mg one per day softgel

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Warnings: Pregnant or lactating women and people with known medical conditions and/or taking drugs should consult with a qualified healthcare practitioner prior to taking dietary supplements.

Do not use if seal is broken.

Keep out of reach of children.

Formulation

Non-GMO Gluten free

Free of: Sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, yeast, wheat, soy, gluten, titanium dioxide, artificial colors and flavors.

General Statements

Naturally provides powerful antioxidant support

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 softgel with meal or as directed by a qualified healthcare practitioner.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

AstaReal is a registered trademark of Fuji Chemical Industry Co., Ltd.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Astaxanthin 12 mg by Nature's Lab label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astaxanthin 12 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astaxanthin 12 mg by Nature's Lab

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

AstaReal Astaxanthin

Interacts with
671 drugs
12 mg per serving Form: Haematococcus pluvialis algae extract

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

AstaReal Astaxanthin monograph & interactions

Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Glycerin, Purified Water, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin 12 mg by Nature's Lab Drug Interactions

Want to check YOUR meds against Astaxanthin 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

AstaReal Astaxanthin 671

Individual Drug Interactions

The ingredients in Astaxanthin 12 mg interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Astaxanthin 12 mg interact with drugs. Each result below shows which ingredient is responsible. AstaReal Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AstaReal Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
AstaReal Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astaxanthin 12 mg, from the product label.

Nature's Lab

See all Nature's Lab products
Name
DrVita Labs
Street Address
6980 W. Warm Springs Road, Suite 100
City
Las Vegas
State
NV
ZipCode
89113
Phone Number
1-888-793-0351
Pharmacist Counseling Corner

Astaxanthin 12 mg by Nature's Lab: Common Questions

Does Astaxanthin 12 mg by Nature's Lab interact with any medications?
Yes. Based on its ingredients, Astaxanthin 12 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. The evidence-based recommendation is to avoid astaxanthin during pregnancy and breastfeeding. Talk with your doctor or pharmacist about your specific situation — they can help you decide whether the benefit might outweigh the unknown risk.
What does astaxanthin actually do?
Astaxanthin is a natural red pigment from algae and seafood that acts as an antioxidant in your body. It's marketed for things like brain health, eye health, and skin aging, but we don't have reliable clinical trial evidence to confirm it works for any of those uses in the data we hold.
Will my stool really turn red?
Yes, red-colored stools are common with astaxanthin and completely harmless — it's just the color of the supplement coming through. If you also see abdominal pain or diarrhea, those are the side effects to watch for, though they're uncommon at this dose.
Is astaxanthin safe to take long-term?
Studies show it's generally well tolerated, but we don't have a lot of long-term safety data. If you plan to take it for months or years, that's worth discussing with your doctor, especially if you're on medications that might be affected by the liver enzyme interaction.
What if I'm on a cholesterol or blood pressure medication?
Many of those drugs are metabolized by the liver enzymes that astaxanthin may speed up, which could lower your medication levels. Check your exact medications with the interaction tool on this page, then talk with your doctor or pharmacist before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astaxanthin 12 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin 12 mg label
Go deeper

The Full Monographs Behind Astaxanthin 12 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Astaxanthin 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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