Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Pau D'Arco Ingredients & Drug Interactions

by BIOVEA

Pau D'Arco label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pau D'Arco against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pau D'Arco is a dietary supplement by BIOVEA with 1 active ingredient. Its ingredients are commonly taken for infections (bacterial, fungal, yeast), inflammation, immune support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ethically wild harvested Pau d'Arco. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pau D'Arco by BIOVEA

Ask about any prescription or over-the-counter medication and we check it for interactions with Pau D'Arco by BIOVEA — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Pau D'Arco by BIOVEA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: ethically wild harvested Pau d'Arco. It comes as a liquid formulation with grain alcohol and deionized water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pau D'arco product and its label doesn't state a use — see Pau D'arco's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that pau d'arco works for cancer, peptic ulcers, wound healing, or dysmenorrhea. For all these uses, the data is currently insufficient to rate it either way.

The evidence, ingredient by ingredient Pau D'arco

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pau d'arco is generally well tolerated at typical doses, but human safety data is limited. At higher doses—specifically lapachol above 1.5 grams daily—it can cause anemia, increased bleeding risk, severe nausea, vomiting, and diarrhea.

The product is not recommended during pregnancy due to possible harm to the developing baby and lack of safety data. There isn't enough information to know whether it's safe while breastfeeding, so it's best to avoid it during lactation as well.

If you're pregnant or nursing and interested in pau d'arco, talk it over with your doctor or pharmacist.

Side effects, ingredient by ingredient Pau D'arco

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pau D'arco.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before combining this product with blood thinners (anticoagulants) like warfarin or heparin, or antiplatelet drugs like aspirin or clopidogrel. Pau d'arco may raise your bleeding risk with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pau d'Arco may appeal to someone looking for traditional plant support, but the effectiveness evidence isn't established in our data. If you take blood thinners or antiplatelet drugs, you need to check with your doctor or pharmacist before starting it—the bleeding risk is the real concern here.

It's not recommended in pregnancy or while breastfeeding. Have your medications and this product reviewed together before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pau D'Arco, straight from the product label.

Brand BIOVEA
Barcode (UPC) 818423028972
Net contents 30 mL; 1 fl. Oz.
Market status On market
Date entered into DSLD Feb 23, 2018
DSLD ID 174649
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pau D'Arco by BIOVEA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
818423028972
IngredientAmount% DV
ethically wild harvested Pau d'Arco0 NP--

Other ingredients: Grain Alcohol, deionized Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

GMP Compliant

K Parve K-1604

Formulation

Vegan product

Non GMO, gluten free

Formula

Pau D'Arco liquid extract

K Parve K-1604

Suggested/Recommended/Usage/Directions

Suggested Daily Intake: Take 30 drops, 1-3 times per day, or as needed in juice or water.

General Statements

Guaranteed premium quality

Liquid extract

FDA Statement of Identity

Herbal Supplement

Precautions

Warning: Keep out of reach of children.

Storage

Shake well before using.

General

#12806 - C17

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pau D'Arco by BIOVEA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pau D'Arco label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pau D'Arco by BIOVEA

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Ethically wild harvested Pau d'Arco

Interacts with
122 drugs
0 NP per serving

Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activit...

Ethically wild harvested Pau d'Arco monograph & interactions

Other (inactive) ingredients: Grain Alcohol, Deionized Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pau D'Arco by BIOVEA Drug Interactions

Want to check YOUR meds against Pau D'Arco?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

ethically wild harvested Pau d'Arco 122

Individual Drug Interactions

The ingredients in Pau D'Arco interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pau D'Arco interact with drugs. Each result below shows which ingredient is responsible. ethically wild harvested Pau d'Arco

Each ingredient & the kinds of drugs it affects

For each ingredient in Pau D'Arco with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ethically wild harvested Pau d'Arco1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that pau d'arco reduces platelet aggregation and may interfere with vitamin K. One clinical study shows that taking the lapachol constituent of pau d'arco in doses above 1.5 grams daily increases the risk of bleeding. The effects of whole pau d'arco or pau d'arco extract in humans are unclear.

Likelihood Possible Evidence D
ethically wild harvested Pau d'Arco full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pau D'Arco, from the product label.

BIOVEA

See all BIOVEA products
Name
BIOVEA
Phone Number
1-800-961-4750
Web Address
www.biovea.com
Pharmacist Counseling Corner

Pau D'Arco by BIOVEA: Common Questions

Does Pau D'Arco by BIOVEA interact with any medications?
Yes. Based on its ingredients, Pau D'Arco has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pau D'Arco contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. The safety data advises against pau d'arco in pregnancy because of possible harm to the developing baby. There isn't enough safety information for breastfeeding either. Talk with your doctor or pharmacist about any herbal options that might be safer for you during this time.
What does pau d'arco actually do?
Pau d'arco has been used traditionally for various conditions, but the evidence we hold doesn't establish that it works for cancer, peptic ulcers, wound healing, or dysmenorrhea. The data is insufficient to rate it for these uses.
What are the side effects at normal doses?
At typical doses, pau d'arco is generally well tolerated, though human safety data is limited. At higher doses—lapachol above 1.5 grams daily—it can cause anemia, increased bleeding, severe nausea, vomiting, and diarrhea.
Will this interact with my blood thinner?
Possibly, yes. Pau d'arco may increase your bleeding risk when taken with anticoagulants (like warfarin) or antiplatelet drugs (like aspirin or clopidogrel). Check your exact medication on this page's tool and confirm with your doctor or pharmacist before starting.
Is this product safe at higher doses?
No. The safety data cautions against higher doses. Lapachol above 1.5 grams daily can cause anemia, bleeding risk, and severe digestive upset. Human safety data is limited overall, so stick with lower doses if you use it, and talk with your pharmacist about what's appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pau D'Arco is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pau D'Arco label
Go deeper

The Full Monographs Behind Pau D'Arco’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pau D'arco

Interacts with 122 drugs

Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activity in lab studies. However, strong human...

Read the full Pau D'arco monograph →
Sources

Sources & How We Checked

Pau D'Arco's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pau D'arco 6 references
  1. Gómez Castellanos JR, Prieto JM, Heinrich M. Red Lapacho (Tabebuia impetiginosa)--a global ethnopharmacological commodity? J Ethnopharmacol 2009;121:1-13. PubMed
  2. Guerra, Mde O., Mazoni, A. S., Brandao, M. A., and Peters, V. M. Toxicology of Lapachol in rats: embryolethality. Braz.J Biol. 2001;61(1):171-174. PubMed
  3. Felicio, A. C., Chang, C. V., Brandao, M. A., Peters, V. M., and Guerra, Mde O. Fetal growth in rats treated with lapachol. Contraception 2002;66(4):289-293. PubMed
  4. Son, D. J., Lim, Y., Park, Y. H., Chang, S. K., Yun, Y. P., Hong, J. T., Takeoka, G. R., Lee, K. G., Lee, S. E., Kim, M. R., Kim, J. H., and Park, B. S. Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular s
  5. Block JB, Serpick AA, Miller W, Wiernik PH. Early clinical studies with lapachol (NSC-11905). Cancer Chemother Rep 2. 1974;4(4):27-8.
  6. Algranti E, Mendonça EM, Ali SA, Kokron CM, Raile V. Occupational asthma caused by Ipe (Tabebuia spp) dust. J Investig Allergol Clin Immunol 2005;15(1):81-3.

See these in context on the Pau D'arco monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team