Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Pump Dirt Ingredients & Drug Interactions

by InnovaPharm

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pump Dirt is a dietary supplement by InnovaPharm with 3 active ingredients. Its ingredients are commonly taken for blood sugar support, type 2 diabetes, sugar cravings.Based on those ingredients, 1,003 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gymnema sylvestre leaf extract, Slin10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pump Dirt by InnovaPharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Pump Dirt contains three active ingredients. Two of them — Gymnema sylvestre leaf extract and Slin10 (a banaba extract) — are plant-based compounds traditionally used in formulas aimed at glucose and metabolic support.

The third, Shikonin, is an ingredient we don't hold data on. The product also contains two inactive ingredients: gelatin (the capsule material) and silica (a flow agent).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: carbohydrate utilization and physical endurance.
  • We looked for evidence on: Impaired glucose tolerance (prediabetes), Metabolic syndrome, Obesity, Blood sugar management, Body composition, Athletic performance.
  • The closest evidence on file: Gymnema is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Gymnema is rated "Insufficient Reliable Evidence To Rate" for Obesity, Impaired glucose tolerance (prediabetes), Metabolic syndrome.
  • Also on file: Banaba is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Impaired glucose tolerance (prediabetes), Metabolic syndrome.

The evidence for these ingredients is sparse. For Gymnema sylvestre, the data rates its use for diabetes, obesity, prediabetes (impaired glucose tolerance), and metabolic syndrome all as insufficient — we don't have reliable evidence to say whether it works for these conditions.

The same holds for Slin10 (banaba): insufficient evidence for diabetes, prediabetes, and metabolic syndrome. We have no effectiveness data on file for Shikonin.

The evidence, ingredient by ingredient Gymnema Banaba

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gymnema is generally well tolerated over the short term, but quality varies widely between products, and it can lower blood sugar. A case of serious liver inflammation (hepatitis) with weakness, fatigue, and jaundice was reported in someone who drank gymnema tea three times daily for 10 days; liver function recovered after 6 months with treatment.

Banaba is generally well tolerated in short studies, but long-term safety isn't established. Some adverse effects reported with a banaba-containing product include dizziness, headache, tremor, weakness, stomach upset, sweating, heart palpitations, and dizziness — though it's unclear whether banaba alone or another ingredient caused them.

Gymnema is not recommended in pregnancy or while breastfeeding due to insufficient safety data. The same applies to banaba.

Side effects, ingredient by ingredient Gymnema Banaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Gymnema, Banaba.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 1,004 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications before taking this product. Priority concerns are blood sugar medications (antidiabetes drugs) and blood pressure medications (antihypertensives) — both pose moderate risk of dangerously additive effects.

Also check any drugs your liver breaks down via CYP1A2, CYP2C9, or CYP3A4 enzymes; Gymnema may raise their levels. Banaba may also reduce absorption of medications that rely on the OATP transporter.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is not for everyone. If you take blood sugar or blood pressure medications, you need to check with your pharmacist or doctor before starting — the risk of low blood sugar or excessive blood pressure drop is real.

Because these ingredients may also affect how dozens of other drugs work, it's essential to run your complete medication list through our interaction checker below. Pregnant or nursing?

Skip this product — there isn't enough safety data.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pump Dirt, straight from the product label.

Brand InnovaPharm
Barcode (UPC) 691054772250
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 299180
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pump Dirt by InnovaPharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
691054772250
IngredientAmount% DV
Gymnema sylvestre leaf extract150 mg--
Slin10350 mg--
Shikonin250 mg--

Other ingredients: Gelatin, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Why dispose of glucose when you can utilize it? Daily use of Pump Dirt can assist with proper utilization of carbohydrates, leading to an increase in physical endurance, all day muscle fullness, prevention of fat storage, and extreme muscle pumps & vascularity.

Enhanced intra-muscular glucose uptake

Dirty pumps Dirty vascularity Dirty muscle fullness Dirty strength & endurance

Twitter Instagram Facebook @InnovaPharm

Allergen information: not manufactured with wheat, gluten, soy, fish, shellfish, egg, milk or tree nut ingredients.

Formula

Pump Dirt contains some of the rarest and most potent herbal extracts known to man, shown to shuttle carbohydrates directly to muscle tissue and away from fat.

Precautions

Warning: this product is only intended to be consumed by adults, 18 years of age or older.

Do not use if you are pregnant or nursing. Before using this product, consult with a licensed, qualified, health care professional, including but not limited to, if you suspect you have or have been treated for, diagnosed with or have a family history of any medical condition, or if you are using any prescription or over the counter medication.

Do not use this product if you have any serious medical conditions. Immediately discontinue use and contacting medical doctor if you experience any adverse reaction to this product. Discontinue use two weeks prior to surgery. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Due to extreme potency, do not consume more than 2 capsules of Pump Dirt in any 24 hour. Use only as directed.

Allergen information: not manufactured with wheat, gluten, soy, fish, shellfish, egg, milk or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Slin10 is a registered trademark of Ayurveda Naturals

Suggested/Recommended/Usage/Directions

Suggested Use: take 1 capsule 15 to 30 minutes before your pre-training meal consisting of at least 60 to 100g of carbohydrates. If you do not consume a pre-training meal, and on non-training days, take 1 capsule 15 to 30 minutes before your largest carbohydrate containing meal of the day.

See for yourself

Pump Dirt by InnovaPharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pump Dirt by InnovaPharm

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gymnema sylvestre leaf extract

Interacts with
851 drugs
150 mg per serving Form: Gymnemic Acid

Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human stu...

Gymnema sylvestre leaf extract monograph & interactions

Slin10

Interacts with
299 drugs
350 mg per serving Form: Banaba Leaf Extract

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may m...

Slin10 monograph & interactions

Shikonin

250 mg per serving Form: Lithospermum erythrorhizon

Other (inactive) ingredients: Gelatin, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pump Dirt by InnovaPharm Drug Interactions

Want to check YOUR meds against Pump Dirt?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,003Drugs
538 Moderate 465 Minor

Ingredients driving the most interactions

Slin10 299

Each ingredient & the kinds of drugs it affects

For each ingredient in Pump Dirt with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gymnema sylvestre leaf extract6 drug types · 851 drugs

Antidiabetes Drugs

Theoretically, taking gymnema with antidiabetes drugs might increase the risk of hypoglycemia.
Gymnema reduces blood glucose levels in some human and animal research. In human studies, it has been shown to enhance the blood glucose lowering effects of hypoglycemic drugs. However, other research in adults with prediabetes or metabolic syndrome suggests that gymnema does not reduce fasting levels of blood glucose. Until more is known, monitor blood glucose levels closely.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Animal and in vitro research shows that gymnema can inhibit the CYP1A2 enzyme. In one animal study, oral administration of gymnema for 7 days increased the plasma concentrations of phenacetin, a CYP1A2 substrate, by about 1.4-fold and reduced the clearance of phenacetin by about 29%.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Animal research shows that gymnema can induce the CYP2C9 enzyme. In one animal study, gymnema caused a 2.4-fold increase in the clearance of tolbutamide, a CYP2C9 substrate, in rats. In vitro research also shows that gymnema can inhibit CYP2C9.

Likelihood Possible Evidence D
Phenacetin

Theoretically, taking gymnema with phenacetin might increase the levels of phenacetin.
Animal research shows that gymnema, administered orally for 7 days, decreases the clearance of phenacetin in a dose-dependent manner by about 21% to 29% and increases plasma levels about 1.3- to 1.4-fold when compared to control.

Likelihood Possible Evidence D
Tolbutamide (Orinase)

Theoretically, taking gymnema with tolbutamide might the decrease levels of tolbutamide.
Animal research shows that gymnema, administered orally for 7 days, increases the clearance of tolbutamide by 2.4-fold when compared to control.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
One in vitro study using rat liver microsomes shows that gymnema can modestly inhibit the CYP3A4 enzyme. However, other in vitro research using human liver microsomes shows that gymnema does not affect CYP3A4 activity. Animal research also shows that gymnema does not alter the function of CYP3A4. In one study in rats, oral administration of gymnema for 7 days did not alter the clearance of amlodipine, a CYP3A4 substrate.

Likelihood Unlikely Evidence D

Slin103 drug types · 299 drugs

Antidiabetes Drugs

Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
Human and animal research suggests that banaba can lower blood glucose levels.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Human and animal research suggests that banaba can lower blood pressure.

Likelihood Probable Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
In vitro research shows that banaba inhibits OATP, particularly OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the absorption of drugs and other compounds.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Pump Dirt, from the product label.

InnovaPharm

See all InnovaPharm products
Name
InnovaPharm
Street Address
53 E Merrick Rd. #215
City
Freeport
State
NY
ZipCode
11520
Web Address
InnovaPharm.com
Pharmacist Counseling Corner

Pump Dirt by InnovaPharm: Common Questions

Does Pump Dirt by InnovaPharm interact with any medications?
Yes. Based on its ingredients, Pump Dirt has a known interaction with 1,003 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pump Dirt contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Pump Dirt if I'm on diabetes medication?
Not without talking to your pharmacist first. Both Gymnema and banaba (Slin10) lower blood sugar on their own, and they may make your diabetes medication work even harder. That raises your risk of dangerously low blood sugar. Your doctor or pharmacist needs to know before you add this product.
What about if I take blood pressure medication?
Check with your pharmacist or doctor. Banaba can lower blood pressure, so adding it to your blood pressure medication could cause your pressure to drop too much. This is a moderate concern and needs a professional eye on your situation.
Is Gymnema safe to use long-term?
The data on long-term safety is limited. One serious case of liver inflammation (hepatitis) was reported in someone who drank gymnema tea three times daily for 10 days, and quality varies between products. We don't have a clear picture of how safe it is over months or years of use.
Can I take this while pregnant or breastfeeding?
No. There isn't enough safety data on Gymnema or banaba during pregnancy or nursing, so both ingredients should be avoided. Talk with your doctor if you're planning to become pregnant or are nursing and interested in glucose or metabolic support.
What are the most common side effects?
With Gymnema, serious side effects are rare but possible (like liver problems). With banaba, a product containing it reported dizziness, headache, tremor, weakness, stomach upset, sweating, and heart palpitations — though it's unclear if banaba itself or another ingredient caused them. Both are generally well tolerated in short-term use.
Why does this product interact with so many medications?
Gymnema affects multiple liver enzymes (CYP1A2, CYP2C9, CYP3A4) that break down hundreds of different drugs. Banaba has its own effects on blood pressure, blood sugar, and how drugs are absorbed. When an ingredient touches multiple metabolic pathways, it touches many medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pump Dirt is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pump Dirt label
Sources

Sources & How We Checked

Pump Dirt's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gymnema 12 references
  1. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. PubMed
  2. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300.
  3. Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Effects of Gymnema sylvestre extract on the pharmacokinetics and pharmacodynamics of glimepiride in streptozotocin induced diabetic rats. Chem Biol Interact. 2016;245:30-8. PubMed
  4. Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285.
  5. Fabio GD, Romanucci V, De Marco A, Zarrelli A. Triterpenoids from Gymnema sylvestre and their pharmacological activities. Molecules. 2014;19(8):10956-81. PubMed
  6. Shiyovich A, Sztarkier I, Nesher L. Toxic hepatitis induced by Gymnema sylvestre, a natural remedy for type 2 diabetes mellitus. Am J Med Sci. 2010;340(6):514-7. PubMed
  7. Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of gymnema sylvestre administration on metabolic syndrome, insulin sensitivity, and insulin secretion. J Med Food. 2017 Aug;20(8):750-54.
  8. Rammohan B, Samit K, Chinmoy D, et al. Human cytochrome P450 enzyme modulation by gymnema sylvestre: a predictive safety evaluation by LC-MS/MS. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S389-S394.
  9. Vaghela M, Sahu N, Kharkar P, Pandita N. In vivo pharmacokinetic interaction by ethanolic extract of gymnema sylvestre with CYP2C9 (tolbutamide), CYP3A4 (amlodipine) and CYP1A2 (phenacetin) in rats. Chem Biol Interact. 2017 Dec 25;278:141-151. PubMed
  10. Vaghela M, Iyer K, Pandita N. In vitro inhibitory effect of gymnema sylvestre extracts and total gymnemic acids fraction on select cytochrome P450 activities in rat liver microsomes. Eur J Drug Metab Pharmacokinet. 2017 Oct 10. PubMed
  11. Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021;
  12. Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed

See these in context on the Gymnema monograph →

Banaba 7 references
  1. Judy WV, Hari SP, Stogsdill WW, et al. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol 2003;87:115-7. PubMed
  2. Kakuda T, Sakane I, Takihara T, et al. Hypoglycemic effect of extracts from Lagerstroemia speciosa L. leaves in genetically diabetic KK-AY mice. Biosci Biotechnol Biochem 1996;60:204-8.
  3. Fukushima, M., Matsuyama, F., Ueda, N., Egawa, K., Takemoto, J., Kajimoto, Y., Yonaha, N., Miura, T., Kaneko, T., Nishi, Y., Mitsui, R., Fujita, Y., Yamada, Y., and Seino, Y. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res C PubMed
  4. Yamaguchi, Y., Yamada, K., Yoshikawa, N., Nakamura, K., Haginaka, J., and Kunitomo, M. Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci 11-25-2006;79(26):2474-2479. PubMed
  5. Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006;34:577-82. PubMed
  6. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
  7. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple

See these in context on the Banaba monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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