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Dietary supplement

Agaricus Bio Ingredients & Drug Interactions

by Atlas World

Agaricus Bio label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agaricus Bio against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agaricus Bio is a dietary supplement by Atlas World with 1 active ingredient. Its ingredients are commonly taken for immune support, general wellness and antioxidant, adjunct interest during cancer care.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agaricus blazei. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Agaricus Bio by Atlas World

Ask about any prescription or over-the-counter medication and we check it for interactions with Agaricus Bio by Atlas World — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Agaricus Bio by Atlas World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Agaricus Bio contains one active ingredient: agaricus blazei, a type of medicinal mushroom. The capsule also includes hydroxypropyl methylcellulose, which is an inactive ingredient that forms the capsule itself.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Agaricus Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune support and healthy blood glucose levels.
  • We looked for evidence on: Diabetes, Hyperlipidemia, Cardiovascular disease (CVD), Cancer, Chemotherapy-induced adverse effects, immune function — and 2 related terms.
  • The closest evidence on file: Agaricus Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cancer (Natural Medicines).
  • Also on file: Agaricus Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Chemotherapy-induced adverse effects, Diabetes, Hyperlipidemia.

The evidence supporting agaricus mushroom for any of its proposed uses—including hay fever, osteoporosis, cancer, heart disease, chemotherapy side effects, and Crohn's disease—is currently insufficient to rate. We don't have reliable data establishing whether it works for any of these conditions.

The evidence, ingredient by ingredient Agaricus Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Agaricus mushroom is generally well tolerated when taken by mouth. The most common side effects reported are abdominal discomfort, diarrhea, and nausea.

Rare but serious adverse effects including allergic reactions, liver damage, and interstitial lung disease (a lung condition) have been documented in the medical literature, particularly in people undergoing chemotherapy or with certain viral infections. During pregnancy, there isn't enough safety data, so supplement doses should be avoided.

The same applies during breastfeeding—there isn't enough data to know whether it's safe, so talk with your doctor or pharmacist before using it while nursing.

Side effects, ingredient by ingredient Agaricus Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agaricus Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Agaricus Bio, double-check any antidiabetes drugs (blood sugar–lowering medications) you're taking with the search tool below. The interaction is Moderate severity, meaning your blood sugar control could shift.

Since the product interacts with 85 individual medications in this category, it's especially important to review your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Agaricus Bio might appeal to someone looking for immune or wellness support, but the evidence for its effectiveness isn't established yet. If you take any diabetes medication, you'll need to check with your pharmacist first because of the risk of low blood sugar.

Anyone with a history of liver problems, lung issues, or a hepatitis B infection should also talk to their pharmacist before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agaricus Bio, straight from the product label.

Brand Atlas World
Barcode (UPC) 831212003332
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 25, 2015
DSLD ID 47226
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agaricus Bio by Atlas World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
831212003332
IngredientAmount% DV
Agaricus blazei1200 mg--

Other ingredients: Hydroxypropyl Methylcellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Simple yet Powerful Since 1995, our company has been dedicated to producing the highest quality Agaricus blazei mushroom products.

Immune Support

Supports A Healthy Immune System Helps Support Healthy Blood Glucose Levels Helps Support Cellular Health

600 mg/capsule

Formulation

Our Wellness Formula contains certified-organic, patented Agaricus blazei mushrooms that are grown, harvested, and processed in the USA.

100% Natural & Vegetarian

Formula

Our processing methods preserve all the natural benefits and enzyme activities of our proprietary strain of Agaricus blazei mushrooms.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug administration. This prodct is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adult, take 2-6 capsules daily or as directed by your health professional.

Precautions

Warnings: Keep out of of reach of children.

If pregnant or breast feeding, consult a health professional before using this product.

Do not use if hypersensitive to mushrooms.

Do not use if safety seal around top of bottle is missing or broken.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agaricus Bio by Atlas World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agaricus Bio label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agaricus Bio by Atlas World

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Agaricus blazei

Interacts with
86 drugs
1200 mg per serving

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects...

Agaricus blazei monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Agaricus Bio by Atlas World Drug Interactions

Want to check YOUR meds against Agaricus Bio?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Agaricus blazei 86

Individual Drug Interactions

The ingredients in Agaricus Bio interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agaricus Bio interact with drugs. Each result below shows which ingredient is responsible. Agaricus blazei

Each ingredient & the kinds of drugs it affects

For each ingredient in Agaricus Bio with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agaricus blazei1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
In one clinical study in patients with type 2 diabetes who are stabilized on conventional oral hypoglycemic agents, 3 of 29 patients taking an agaricus mushroom extract 500 mg three times daily for 12 weeks reported hypoglycemia, compared to one of 29 patients in the placebo group.

Likelihood Possible Evidence D
Agaricus blazei full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agaricus Bio, from the product label.

Atlas World

See all Atlas World products
Name
Atlas World USA
City
Torrance
State
CA
ZipCode
90502
Phone Number
866-670-6644
Web Address
www.atlasworldusa.com
Pharmacist Counseling Corner

Agaricus Bio by Atlas World: Common Questions

Does Agaricus Bio by Atlas World interact with any medications?
Yes. Based on its ingredients, Agaricus Bio has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agaricus Bio contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
The most often reported side effects are abdominal discomfort, diarrhea, and nausea. Serious side effects are rare but have included allergic reactions and liver or lung problems in some cases.
Can I take this while pregnant?
There isn't enough safety data available, so supplement doses should be avoided during pregnancy. Talk with your doctor or pharmacist about whether it's right for you.
Can I take this while breastfeeding?
There isn't enough data to know whether it's safe while breastfeeding, so you should avoid supplement doses. Check with your pharmacist or doctor for personalized advice.
Does agaricus mushroom actually work for anything?
The evidence isn't established yet for any of the conditions it's proposed for—hay fever, osteoporosis, cancer, heart disease, chemotherapy side effects, and Crohn's disease all have insufficient reliable evidence to rate.
Why do I need to check my diabetes medications?
Agaricus mushroom may lower blood sugar, and when combined with diabetes drugs, that could push your levels too low. A small number of people on both reported low blood sugar episodes in a trial, so monitoring matters.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Agaricus Bio is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agaricus Bio label
Go deeper

The Full Monographs Behind Agaricus Bio’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agaricus Mushroom

Interacts with 86 drugs

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not...

Read the full Agaricus Mushroom monograph →
Sources

Sources & How We Checked

Agaricus Bio's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agaricus Mushroom 5 references
  1. Hsu CH, Liao YL, Lin SC, et al. The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med 2
  2. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol 2006;36:808-10. PubMed
  3. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
  4. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.
  5. Iwai N, Okuda T, Sawada R, et al. Interstitial lung disease associated with Agaricus blazei Murill in a patient with pancreatic ductal adenocarcinoma receiving gemcitabine-based therapy. Case Rep Gastroenterol 2022;16(1):229-234.

See these in context on the Agaricus Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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