Hemp Oil Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hemp Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hemp Oil is a dietary supplement by Terry Naturally with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are concentrated European Hemp (Cannabis sativa) stalk and seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hemp Oil by Terry Naturally
Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp Oil by Terry Naturally — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hemp Oil by Terry Naturally
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: concentrated European hemp (Cannabis sativa) stalk and seed oil. The inactive ingredients are sunflower oil, gelatin, glycerin, purified water, and annatto (a natural colorant).
Does it work?
Couldn't assess
The evidence we hold on hemp oil's effectiveness is insufficient to rate it for any of the conditions studied — constipation, atopic dermatitis (eczema), and familial hypercholesterolemia (high cholesterol due to genetics). That doesn't mean it doesn't work; it means we don't have reliable data yet to make that call.
How safe is it?
Well-documented data
Hemp seed oil appears generally well tolerated in food amounts and in typical supplement doses. However, concentrated extracts and supplements are less studied than food sources, so caution is advised with this product.
Serious side effects are rare but have been reported: anaphylaxis (severe allergic reaction), allergic reactions including facial swelling and shortness of breath, and in one case report of a young child given very high doses of hemp extract, elevated liver enzymes and hepatitis. Allergy to hemp seed itself is uncommon but possible.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take estrogen therapy or hormone replacement (Moderate interaction risk), blood pressure medications including ACE inhibitors, blood thinners (anticoagulants or antiplatelet drugs), or any medication broken down by your liver's CYP1A2 or CYP3A4 enzymes — a category that includes many common drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is a single-ingredient hemp oil supplement. If you take estrogen therapy, blood pressure medications, blood thinners, or drugs metabolized through your liver, you'll want to review your specific medications with your doctor or pharmacist before adding this.
Even though hemp seed is common in food, concentrated supplements are less well studied, so discussing it with your healthcare provider first makes sense.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hemp Oil, straight from the product label.
| Brand | Terry Naturally |
|---|---|
| Barcode (UPC) | 367703375836 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 203424 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hemp Oil by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| concentrated European Hemp (Cannabis sativa) stalk and seed Oil | 50 mg | -- |
Other ingredients: Sunflower Oil, Gelatin, Glycerin, purified Water, Annatto
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Money-back guarantee
Premium European
Supports the Endocannabinoid System
For your good health Terry
It is one of the most highly-regarded botanical ingredients available.
My pledge and promise to you Our products are inspired by my dedication to natural health and passion to make your life better. My goal is to find the best ingredients and develop products to deliver results you can depend on. If you're not satisfied, I have not earned your trust or your money. Therefore, I offer you an unconditional money-back guarantee. That is my pledge and promise to you. Terry Lemerond, Founder and President of Terry Naturally
Concentrated for enhanced benefits Supercritical CO2 extract JC 34 91 + 3(5,6)EP BX37583.02
Formula
Terry Naturally’s Hemp Oil is produced via a clean, chemical-free, supercritical CO2 extraction process. The concentrated hemp oil comes from plants that have been specifically cultivated and carefully selected to contain a full spectrum of phytonutrients to support the body’s endocannabinoid system.
Additionally, the European hemp used in this product is non-GMO and farmed according to eco-friendly practices.
Suggested/Recommended/Usage/Directions
Recommendations: 1 softgel daily. May increase as desired.
Precautions
If pregnant or nursing, consult a healthcare practitioner before use.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease
General
JC 34 91 + 3(5,6)EP L37583.01
FDA Statement of Identity
Dietary Supplement
Formulation
No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.
Non-GMO
Terry Naturally’s Hemp Oil is produced via a clean, chemical-free, supercritical CO2 extraction process.
Seals/Symbols
Verdant Oasis Certified VO Genuine European Hemp
Brand IP Statement(s)
Terry Naturally EuroPharma
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hemp Oil by Terry Naturally label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hemp Oil by Terry Naturally
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Concentrated European Hemp (Cannabis sativa) stalk and seed Oil
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Concentrated European Hemp (Cannabis sativa) stalk and seed Oil monograph & interactionsOther (inactive) ingredients: Sunflower Oil, Gelatin, Glycerin, Purified Water, Annatto. These complete the product’s ingredient list but are not active constituents.
Hemp Oil by Terry Naturally Drug Interactions
HelloPharmacist Interaction Report
Terry Naturally Hemp Oil interacts with medications through its concentrated hemp stalk and seed oil content.
The most serious documented interaction is Moderate in severity: hemp may theoretically interfere with estrogen therapy (hormone replacement therapy) due to its own estrogenic effects, though the exact mechanism isn't fully understood.
Read the full breakdown — every affected drug type, severity by severity
Minor interactions are documented with blood pressure medications (antihypertensives and ACE inhibitors), where hemp seed protein may have additive blood-pressure-lowering effects. There's also a theoretical Minor risk of increased bleeding with blood thinners (anticoagulants/antiplatelets), though human research on the oil itself at typical doses hasn't shown this effect.
Additionally, hemp may theoretically decrease the effectiveness of certain medications metabolized through your liver's CYP1A2 and CYP3A4 pathways — these are enzymes that break down many common drugs.
Altogether, these interactions span 939 individual medications. Because the product contains only one ingredient and we have interaction data for it, check your exact medications with the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hemp Oil?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hemp Oil interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in Hemp Oil interact with drugs. Each result below shows which ingredient is responsible. concentrated European Hemp (Cannabis sativa) stalk and seed Oil
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with Hemp Oil — through 1 ingredient. Tap an ingredient for the detail:
Concentrated European Hemp (cannabis Sativa) Stalk And Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Concentrated European Hemp (cannabis Sativa) Stalk And Seed Oil + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hemp Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
concentrated European Hemp (Cannabis sativa) stalk and seed Oil
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Hemp Oil, from the product label.
Terry Naturally
See all Terry Naturally products- Name
- EuroPharma, Inc.
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- (866) 807-2731
- Web Address
- EuroPharmaUSA.com
Hemp Oil by Terry Naturally: Common Questions
Does Hemp Oil by Terry Naturally interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is this hemp oil made from?
Does it contain THC or CBD?
Are there side effects I should know about?
Is this safe during pregnancy or breastfeeding?
Will this help with eczema or high cholesterol?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hemp Oil is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hemp Oil’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hemp Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC