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Dietary supplement

Moringa 4:1 Ingredients & Drug Interactions

by WiseLife Naturals

Moringa 4:1 label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Moringa 4:1 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Moringa 4:1 is a dietary supplement by WiseLife Naturals with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement, blood sugar support, cholesterol support.Based on those ingredients, 869 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Moringa oleifera (leaf) powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Moringa 4:1 by WiseLife Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Moringa 4:1 by WiseLife Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Moringa 4:1 by WiseLife Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: moringa oleifera (leaf) powder, a dried and concentrated leaf extract presented in a 4:1 ratio, meaning four parts fresh leaf have been reduced to one part powder. The inactive ingredients are microcrystalline cellulose (a binder), magnesium stearate (a lubricant), silicon dioxide (an anti-caking agent), and a vegetable capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Moringa's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight loss for all body types.
  • We looked for evidence on: Obesity, weight management, metabolic support.
  • The closest evidence on file: Moringa is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence on moringa for most uses is insufficient to establish whether it actually works. We hold no reliable data supporting its use for iron deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, or high cholesterol (hyperlipidemia).

While moringa is popular in traditional medicine and contains various nutrients, human clinical trials haven't yet confirmed benefit for any of these conditions. Talk with your doctor about whether moringa makes sense for your specific health goal.

The evidence, ingredient by ingredient Moringa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Moringa leaf is generally well tolerated when used in food amounts, though high-quality safety data are limited. The most common side effect is transient diarrhea; in one clinical trial, about one in four participants taking 8 grams daily experienced it.

Rare serious reactions—including allergic reactions and anaphylaxis—have been reported, and a handful of cases of Stevens-Johnson syndrome (a severe skin and mucous-membrane reaction) have been linked to moringa leaf consumption. Avoid medicinal amounts because the root and bark may stimulate the uterus, and safety data for these parts are lacking.

Moringa is traditionally used to boost milk supply, but safety in lactation hasn't been well studied, so use caution if you're breastfeeding.

Side effects, ingredient by ingredient Moringa

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Moringa.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 870 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any drugs metabolized by the CYP3A4 enzyme pathway (Moderate severity)—moringa's effect on these is unpredictable and may reduce their effectiveness or allow them to build up. Also double-check if you take levothyroxine (Synthroid, others) for thyroid replacement, P-glycoprotein substrate medications, antidiabetes drugs, or drugs broken down by the CYP1A2 enzyme, as documented interactions exist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Moringa leaf powder is marketed for several chronic health conditions, but evidence of effectiveness is not established in the data we hold. If you take thyroid medication, any CYP3A4 substrate drug, or blood-sugar medication, check with your doctor or pharmacist before adding this supplement—documented interactions could affect how those medications work.

Diarrhea is common at higher doses, and rare serious allergic or skin reactions have been reported.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Moringa 4:1, straight from the product label.

Brand WiseLife Naturals
Barcode (UPC) 0852659365685
Net contents 120 Cap(s)
Market status On market
Date entered into DSLD Jan 22, 2022
DSLD ID 258694
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Moringa 4:1 by WiseLife Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s), 4 Capsule(s)
Maximum serving Sizes:
2 Capsule(s), 4 Capsule(s)
Servings per container
30
UPC/BARCODE
0852659365685
IngredientAmount% DV
Moringa oleifera (leaf) powder1200 mg, 2400 mg--

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

100% natural

Learn more about Moringa Super Concentrate: Visit: WiseLifeNaturals.com Facebook Twitter Instagram

Servings per Container: 60 30

Formulation

Weight-loss for all body types

100% pure & natural Safe fat reduction

Non-stimulant No-caffeine

Super concentrated

Made In USA

Precautions

Caution: Do not exceed recommended dose.

Please consult your healthcare provider before using this product if you are pregnant, breastfeeding, or are currently taking any prescription medications.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

The statements on this product have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Certified Made In An FDA Registered Facility

Formula

2400 mg

30 day supply

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 capsules daily or as directed by a health care professional. Max Support Dosage: Take 2 capsules twice daily or as directed by a health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Moringa 4:1 by WiseLife Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Moringa 4:1 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Moringa 4:1 by WiseLife Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Moringa oleifera (leaf) powder

Interacts with
869 drugs
1200 mg per serving

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....

Moringa oleifera (leaf) powder monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Moringa 4:1 by WiseLife Naturals Drug Interactions

Want to check YOUR meds against Moringa 4:1?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
869Drugs
717 Moderate 152 Minor

Ingredients driving the most interactions

Moringa oleifera (leaf) powder 869

Individual Drug Interactions

The ingredients in Moringa 4:1 interact with 869 drugs. Click any drug to see the details.

1 of the 1 ingredient in Moringa 4:1 interact with drugs. Each result below shows which ingredient is responsible. Moringa oleifera (leaf) powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Moringa 4:1 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Moringa oleifera (leaf) powder6 drug types · 869 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Possible Evidence D
Levothyroxine (Synthroid, Others)

Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Nevirapine (Viramune)

Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Unlikely Evidence B
Moringa oleifera (leaf) powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Moringa 4:1, from the product label.

WiseLife Naturals

See all WiseLife Naturals products
Name
WiseLifeNaturals Inc
City
Ashland
State
OR
ZipCode
97520
Web Address
WiseLifeNaturals.com
Pharmacist Counseling Corner

Moringa 4:1 by WiseLife Naturals: Common Questions

Does Moringa 4:1 by WiseLife Naturals interact with any medications?
Yes. Based on its ingredients, Moringa 4:1 has a known interaction with 869 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Moringa 4:1 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is moringa safe while breastfeeding?
Moringa is traditionally used to support milk supply, and we have a 'Possibly Safe' rating for lactation, but safety hasn't been well studied. Talk with your doctor or pharmacist about whether it's appropriate for you, since individual risk and benefit can vary.
Is moringa safe during pregnancy?
Our data show conflicting ratings—'Possibly Safe' and 'Possibly Unsafe'—which reflects genuine uncertainty about safety in pregnancy. Because the root and bark may stimulate the uterus and safety data are limited, avoid medicinal amounts, and discuss use with your doctor or pharmacist before starting.
What's the most common side effect?
Diarrhea is the most common side effect when taken orally, and it's usually temporary. In one trial, about one in four people taking 8 grams daily experienced it. Rare serious reactions, including severe allergic reactions and skin syndromes, have also been reported.
Does moringa actually help with diabetes or high cholesterol?
We hold insufficient reliable evidence to say whether moringa helps either condition. While it's used traditionally for both, human clinical trials haven't confirmed benefit yet, so talk with your doctor about whether it's right for your situation.
What is this 4:1 ratio?
A 4:1 ratio means four parts fresh moringa leaf have been concentrated down to one part powder, making it more potent by weight than a simple dried powder. It's a way to standardize the ingredient's strength.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Moringa 4:1 label
Go deeper

The Full Monographs Behind Moringa 4:1’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Moringa

Interacts with 869 drugs

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common. Early research hints at possible benefi...

Read the full Moringa monograph →
Sources

Sources & How We Checked

Moringa 4:1's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Moringa 23 references
  1. Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
  2. Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000;41:319-23. PubMed
  3. Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
  4. Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
  5. Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
  6. Monera TG, Wolfe AR, Maponga CC, et al. Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2008;2:379-83.
  7. Estrella M, Mantaring J, David G, Taup M. A double blind, randomised controlled trial on the use of malunggay (Moringa oleifera) for augmentation of the volume of breastmilk among non-nursing mothers of preterm infants. Philipp J Pediatr 2000;49:3-6.
  8. Morton, J. F. The Horseradish Tree, Moringa Pterygosperma (Moringaceae) - a boon to arid lands? Economic Botany 1991;45:318-333. DOI
  9. Espinosa-Kuo CL. A Randomized Controlled Trial on the Use of Malunggay (Moringa oleifera) for Augmentation of the Volume of Breastmilk Among Mothers of Term Infants. Filipino Family Physician. 2005;43(1):26-33.
  10. King JS, Raguindin PFN, Dans LF. Moringa oleifera (Malunggay) as a Galactagogue for Breastfeeding Mothers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Philipp J Pediatr 2013;61(2):34-42.
  11. Singh D, Choudhury S, Singh TU, Garg SK. Pharmacodynamics of uterotonic effect of Moringa oleifera flowers extract. J Vet Pharmcol Toxicol 2008;7(1-2):12-15.
  12. William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
  13. Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017;14:12. doi: 10.1186/s1 PubMed
  14. Witharana EWRA, Wijetunga WMGASTB, Wijesinghe SKJ. Stevens - Johnson syndrome (SJS) following murunga leaf (Moringa oleifera) consumption. Ceylon Med J 2018;63(4):188-9.
  15. Nur R, Demak IPK, Radhiah S, Rusydi M, Mantao E, Larasati RD. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women. Enferm Clin. 2020;30 Suppl 4:79-82. DOI
  16. Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M
  17. Sumiaty, Tahir A, Burhanuddin B, Nurhaedar J, Veni H. The effect of moringa leaves on pregnancy on growth and morbidity of 6-11 month. Enferm Clin. 2020;30 Suppl 4:104-108. DOI
  18. Ulmy MN, Tahir A, Arsunan AA, Burhanuddin B, Veni H. Effect of moringa leaves during pregnancy on growth and morbidity in 0-5 months. Enferm Clin. 2020;30 Suppl 4:61-65. DOI
  19. Amaeze O, Marques ES, Wei W, et al. Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction. Curr Drug Metab. 2021;22(14):1103-1113. PubMed
  20. Ebhohon E, Miller D. Moringa Oleifera leaf extract induced pulmonary embolism-a case report. Int J Emerg Med 2022;15(1):16. PubMed
  21. Basri H, Hadju V, Zulkifli A, Syam A, Indriasari R. Effect of Moringa oleifera supplementation during pregnancy on the prevention of stunted growth in children between the ages of 36 to 42 months. J Public Health Res 2021;10(2):2207.
  22. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  23. Amsler E, Mahevas T, Soria A, Barbaud A. Fixed food eruption to Moringa oleifera. Contact Dermatitis 2023;89(4):301-302.

See these in context on the Moringa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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