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Dietary supplement

Shilajit Churna 17 Ingredients & Drug Interactions

by Ayurvedic Rasayanas

Shilajit Churna 17 label
See full label image
Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Shilajit Churna 17 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Shilajit Churna 17 is a dietary supplement by Ayurvedic Rasayanas with 4 active ingredients.Based on those ingredients, 1,629 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Shilajit Churna 17 by Ayurvedic Rasayanas

Ask about any prescription or over-the-counter medication and we check it for interactions with Shilajit Churna 17 by Ayurvedic Rasayanas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Shilajit Churna 17 by Ayurvedic Rasayanas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 21 active ingredients.
  • “Dietary Ingredients” is listed as a grouped ingredient — the label gives one combined amount (3 Gram(s)) without saying how much of each component you get.
  • “Proprietary Blend of Standardized Extracts and Powdered Herbs” is a proprietary blend — the label doesn't break down how much of each component you get.

Shilajit Churna 17 contains 21 ingredients, of which the main active ones are traditional Ayurvedic plant extracts and powders: shilajit, gymnema, bitter melon, gotu kola, guduchi (Tinospora cordifolia), guggulu, pippali (Indian long pepper), neem, amalaki (Indian gooseberry), tulasi (holy basil), barberry, turmeric, fenugreek, dandelion, ginger, black pepper, and cinnamon. The product also lists inactive ingredients in the form of fillers and binders, though none are detailed on the label.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Pancreas, digestion and metabolism support.
  • We looked for evidence on: Digestive health, Metabolic function, Pancreatic health, Blood sugar regulation.
  • The closest evidence on file: Neem is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome (Natural Medicines).
  • Also on file: Turmeric is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome.
  • Also on file: Fenugreek is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome.

For most conditions this formula targets, the evidence we hold is mixed or limited. Turmeric shows Possibly Effective evidence for depression, high cholesterol (hyperlipidemia), and allergic rhinitis.

Ginger is Possibly Effective for pregnancy-related nausea and vomiting and menstrual pain (dysmenorrhea). Neem, guduchi, and fenugreek are Possibly Effective for diabetes.

Gotu kola is Possibly Effective for poor circulation (venous insufficiency) and burns. Gokshura (tribulus) is Possibly Effective for sexual dysfunction.

For many other uses—athletic performance, cognitive function, osteoporosis, weight loss, and others—the evidence in our data is insufficient to rate these ingredients. Claims about this product's other benefits cannot be confirmed from the data we hold.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 17 of the 18 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 18 of 18.
  • General safety write-ups exist for 18 of 18.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in this formula are generally well tolerated short-term in typical doses, though quality and long-term safety data vary. Ginger, in particular, is generally well tolerated at food and moderate supplement amounts.

However, several ingredients carry important caveats. Shilajit must be from a purified, tested brand because unpurified products may contain heavy metals or contaminants.

Neem oil and seeds are toxic if swallowed; only leaf preparations are appropriate. Gotu kola has four reported case reports of liver injury, though a clinical trial at 120 mg daily for 6 months showed no liver changes.

Guduchi (Tinospora cordifolia) has been linked to liver injury in 49 cases over a median of 42–90 days of use, with 2 requiring transplant and 4 resulting in death. Turmeric has at least 70 reports of liver damage, most resolving after stopping the supplement.

Guggulu and fenugreek may cause digestive upset and skin reactions. Most common side effects across the formula are gastrointestinal—nausea, diarrhea, heartburn, bloating—and occur in small numbers of users.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 18 of the 18 matched ingredients can interact with medications — Tribulus, Ceylon Cinnamon, Indian Long Pepper, European Barberry, Neem, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; diabetes medications; lithium.
  • For scale: 1,630 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take antidiabetes drugs (Moderate risk of low blood sugar across multiple ingredients), blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate risk of bleeding), drugs metabolized by your liver's cytochrome P450 enzymes—especially CYP3A4, CYP2C9, CYP2D6, CYP1A2, or CYP2C19 (Moderate risk of level changes), blood pressure medications (Moderate risk), lithium (Moderate risk), theophylline (Moderate risk), or immunosuppressants (Moderate risk). Other Moderate interactions include propranolol, diltiazem, specific cancer drugs, tacrolimus, and several others listed in the full breakdown.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a traditional Ayurvedic blend used for various purposes, with some ingredients showing limited evidence for specific conditions like diabetes, nausea, and poor circulation. If you take blood sugar medications, blood thinners, heart drugs, or any prescription medication, you'll want to check your exact drugs with the tool on this page because multiple ingredients interact with many common classes of medication.

Anyone with liver disease, a history of liver problems, or those taking immunosuppressants or cancer medications should discuss this product with their doctor or pharmacist before starting it. Talk it over with your own doctor or pharmacist to see if it's right for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 18 of 21 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Shilajit Churna 17, straight from the product label.

Brand Ayurvedic Rasayanas
Net contents 5.3 Ounce(s); 150 Gram(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 246265
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Shilajit Churna 17 by Ayurvedic Rasayanas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Teaspoon(s)
Maximum serving Sizes:
3 Teaspoon(s)
Servings per container
50
IngredientAmount% DV
Calories11 Calorie(s)--
Total Carbohydrates2 Gram(s)--
Sugar0 Gram(s)--
Protein0 Gram(s)--
Saturated Fat0 Gram(s)--
Fat0 Gram(s)--
Dietary Ingredients3 Gram(s)--
Proprietary Blend of Standardized Extracts and Powdered Herbs0 NP--
Shilajit extract powder0 NP--
Gymnema leaf extract powder0 NP--
Bitter Melon fruit extract powder0 NP--
Gokshura fruit extract powder0 NP--
Gotu Kola leaf extract powder0 NP--
Guduchi leaf extract powder0 NP--
Guggulu resin extract powder0 NP--
Pippali fruit extract powder0 NP--
Neem leaf extract powder0 NP--
Amalaki fruit extract powder0 NP--
Haritaki fruit extract powder0 NP--
Tulasi root extract powder0 NP--
Barberry root extract powder0 NP--
Turmeric root extract powder0 NP--
Fenugreek seed extract powder0 NP--
Dandelion root extract powder0 NP--
Triphala extract powder0 NP--
Ginger root extract powder0 NP--
Black Pepper fruit extract powder0 NP--
Cinnamon bark extract powder0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Shilajit churna is a combination of dried powdered extracts, raw powdered herbs and spices. This combination of herbs creates a perfect symphony of natural chemistry that supports the whole body.

Formulation

Herbs and spices have been used for centuries as a natural preventive to fight disease, improve digestion and help maintain a healthy mind, body and soul.

Recommendations: Pancreas, Digestion, Metabolism. Kapha or Earth balancing

GF Certified Gluten-free

Pancreas Support

Suggested/Recommended/Usage/Directions

Dosage: one teaspoon per 50lbs of weight Dissolve 1 to 3 tsp. in hot water 30 min. before meals.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GF Certified Gluten-free

FDA Statement of Identity

Dietary Supplement

General Statements

Not a significant source of vitamin A, vitamin C, calcium and iron

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Shilajit Churna 17 by Ayurvedic Rasayanas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Shilajit Churna 17 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Shilajit Churna 17 by Ayurvedic Rasayanas

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Teaspoon(s) Dosage formOther (e.g. Tea Bag) Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Protein

0 Gram(s) per serving

Fat

0 Gram(s) per serving

Dietary Ingredients

3 Gram(s) per serving
  • › Proprietary Blend of Standardized Extracts and Powdered Herbs
Interaction report

Shilajit Churna 17 by Ayurvedic Rasayanas Drug Interactions

Want to check YOUR meds against Shilajit Churna 17?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,629Drugs
1,623 Moderate 6 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Shilajit Churna 17 interact with 1,629 drugs. Click any drug to see the details.

0 of the 4 ingredients in Shilajit Churna 17 interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Shilajit Churna 17 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Shilajit Churna 17, from the product label.

Ayurvedic Rasayanas

See all Ayurvedic Rasayanas products
Name
Ayurvedic Rasayanas
Street Address
P.O. Box 719
City
Ashland
State
OR
ZipCode
97520
Phone Number
541-944-7243
Web Address
www.ayurveda-herbs.com
Pharmacist Counseling Corner

Shilajit Churna 17 by Ayurvedic Rasayanas: Common Questions

Does Shilajit Churna 17 by Ayurvedic Rasayanas interact with any medications?
Yes. Based on its ingredients, Shilajit Churna 17 has a known interaction with 1,629 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Shilajit Churna 17 contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
Most ingredients in this formula should be avoided during pregnancy due to insufficient safety data or active warnings. Shilajit in particular is not recommended because unpurified products may contain harmful contaminants. Turmeric at supplement doses is also rated Likely Unsafe in pregnancy. Ginger is an exception and is Likely Safe for morning sickness, but keep amounts modest and check with your doctor first. For breastfeeding, safety data is limited for nearly all ingredients, so talk with your doctor or pharmacist before starting.
Can this product cause liver damage?
Several ingredients in this formula—notably guduchi, turmeric, and gotu kola—have been linked to liver injury in case reports. Guduchi has 49 reported cases over 42–90 days of use, and turmeric has at least 70 reports, though most resolved after stopping. Gotu kola has four cases on record. If you have liver disease or take medications that stress the liver, discuss this product with your doctor before use.
Will this lower my blood sugar or interact with diabetes medications?
Yes—multiple ingredients (shilajit, gymnema, bitter melon, guduchi, neem, amalaki, tulasi, fenugreek, and cinnamon) have been shown to lower blood glucose levels. Taking this with antidiabetes drugs carries a Moderate risk of hypoglycemia (low blood sugar). If you use diabetes medications, check your exact drugs with our tool and discuss this product with your doctor or pharmacist before starting.
What are the most common side effects?
The most common side effects are gastrointestinal—nausea, diarrhea, heartburn, bloating, stomach discomfort, and flatulence—reported by a small number of users. Headache has also been reported. These are generally mild and often dose-dependent. If you experience severe or persistent symptoms, stop and talk to your doctor.
Does this really work for diabetes, digestion, or other health claims?
Evidence varies. Turmeric, ginger, guduchi, and fenugreek show some evidence for diabetes support, though it's often limited. Ginger has more solid evidence for nausea and menstrual pain. For most other uses—weight loss, digestion, general wellness—the evidence in our data is insufficient to confirm benefit. This is a traditional formula, but modern proof is incomplete.
Should I worry about heavy metals or contaminants in this product?
Shilajit specifically carries a risk of heavy metal contamination if the product is not purified and tested. The label does not specify whether this batch has been tested. Choose only purified, tested brands of shilajit. For the other herbs in the formula, quality standards vary, so buy from a reputable manufacturer and look for third-party testing if available.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Shilajit Churna 17 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Shilajit Churna 17 label
Sources

Sources & How We Checked

Shilajit Churna 17's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 446 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Shilajit 8 references
  1. Sadeghi SMH, Hosseini Khameneh SM, Khodadoost M, et al. Efficacy of momiai in tibia fracture repair: A randomized double-blinded placebo-controlled clinical trial. J Altern Complement Med 2020;26(6):521-528.
  2. Losa F, Deidda M, Firinu D, Martino MLD, Barca MP, Giacco SD. Exercise-induced anaphylaxis with an Ayurvedic drug as cofactor: A case report. World J Clin Cases 2019;7(5):623-627. PubMed
  3. Biswas TK, Pandit S, Mondal S, et al. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia 2010;42(1):48-56. PubMed
  4. Stavropoulos K, Sotiriadis A, Patoulias D, et al. Pseudohyperaldosteronism due to mumijo consumption during pregnancy: a licorice-like syndrome. Gynecol Endocrinol 2018;34(12):1019-1021. PubMed
  5. Ghezelbash B, Shahrokhi N, Khaksari M, Ghaderi-Pakdel F, Asadikaram G. Hepatoprotective effects of shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats. Horm Mol Biol Clin Investig 2020;41(1):/j/hmbci. PubMed
  6. Ghezelbash B, Shahrokhi N, Khaksari M, Asadikaram G, Shahrokhi M, Shirazpour S. Protective roles of shilajit in modulating resistin, adiponectin, and cytokines in rats with non-alcoholic fatty liver disease. Chin J Integr Med 2022;28(6):531-537. PubMed
  7. Jafari M, Forootanfar H, Ameri A, et al. Antioxidant, cytotoxic and hyperalgesia-suppressing activity of a native Shilajit obtained from Bahr Aseman mountains. Pak J Pharm Sci 2019;32(5):2167-2173. DOI
  8. Trivedi NA, Mazumdar B, Bhatt JD, Hemavathi KG. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats. Ind. J. Pharmacol. 2004; 36(6):373-376.

See these in context on the Shilajit monograph →

Gymnema 12 references
  1. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. PubMed
  2. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300.
  3. Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Effects of Gymnema sylvestre extract on the pharmacokinetics and pharmacodynamics of glimepiride in streptozotocin induced diabetic rats. Chem Biol Interact. 2016;245:30-8. PubMed
  4. Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285.
  5. Fabio GD, Romanucci V, De Marco A, Zarrelli A. Triterpenoids from Gymnema sylvestre and their pharmacological activities. Molecules. 2014;19(8):10956-81. PubMed
  6. Shiyovich A, Sztarkier I, Nesher L. Toxic hepatitis induced by Gymnema sylvestre, a natural remedy for type 2 diabetes mellitus. Am J Med Sci. 2010;340(6):514-7. PubMed
  7. Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of gymnema sylvestre administration on metabolic syndrome, insulin sensitivity, and insulin secretion. J Med Food. 2017 Aug;20(8):750-54.
  8. Rammohan B, Samit K, Chinmoy D, et al. Human cytochrome P450 enzyme modulation by gymnema sylvestre: a predictive safety evaluation by LC-MS/MS. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S389-S394.
  9. Vaghela M, Sahu N, Kharkar P, Pandita N. In vivo pharmacokinetic interaction by ethanolic extract of gymnema sylvestre with CYP2C9 (tolbutamide), CYP3A4 (amlodipine) and CYP1A2 (phenacetin) in rats. Chem Biol Interact. 2017 Dec 25;278:141-151. PubMed
  10. Vaghela M, Iyer K, Pandita N. In vitro inhibitory effect of gymnema sylvestre extracts and total gymnemic acids fraction on select cytochrome P450 activities in rat liver microsomes. Eur J Drug Metab Pharmacokinet. 2017 Oct 10. PubMed
  11. Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021;
  12. Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed

See these in context on the Gymnema monograph →

Bitter Melon 18 references
  1. Leatherdale B, Panesar RK, Singh G, et al. Improvement in glucose tolerance due to Momordica charantia. Br Med J (Clin Res Ed) 1981;282:1823-4.
  2. Welihinda J, et al. Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. J Ethnopharmacol 1986;17:277-82. PubMed
  3. Srivastava Y, Venkatakrishna-Bhatt H, Verma Y, et al. Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother Res 1993;7:285-9.
  4. Baldwa VS, Bhandari CM, Pangaria A, Goyal RK. Clinical trial in patients with diabetes mellitus of an insulin-like compound obtained from plant sources. Ups J Med Sci 1977;82:39-41. PubMed
  5. Aslam M, Stockley IH. Interaction between curry ingredient (karela) and drug (chlorpropamide). Lancet 1979:1:607. PubMed
  6. Ahmad N, Hassan MR, Halder H, Bennoor KS. Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients (abstract). Bangladesh Med Res Counc Bull 1999;25:11-3.
  7. Basch E, Gabardi S, Ulbricht C. Bitter melon (Momordica charantia): a review of efficacy and safety. Am J Health Syst Pharm 2003;60:356-9. PubMed
  8. Yin RV, Lee NC, Hirpara H, Phung OJ. T. The effect of bitter melon (Mormordica charantia) in patients with diabetes mellitus: s systematic review and meta-analysis. Nutr Diabetes. 2014;4:e145.
  9. Rahman IU, Khan RU, Rahman KU, Bashir M. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients. Nutr J. 2015;14:13. PubMed
  10. Alam MA, Uddin R, Subhan N, Rahman MM, Jain P, Reza HM. Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome. J Lipids. 2015;2015:496169. PubMed
  11. Konishi T, Satsu H, Hatsugai Y, et al. Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. Br J Pharmacol. 2004;143(3):379-87. PubMed
  12. Peter EL, Kasali FM, Deyno S, et al. Momordica charantia L. lowers elevated glycaemia in type 2 diabetes mellitus patients: Systematic review and meta-analysis. J Ethnopharmacol. 2019;231:311-24. doi: 10.1016/j.jep.2018.10.033. PubMed
  13. Cortez-Navarrete M, Martínez-Abundis E, Pérez-Rubio KG, González-Ortiz M, Méndez-Del Villar M. Momordica charantia administration improves insulin secretion in type 2 diabetes mellitus. J Med Food. 2018;21(7):672-7. doi: 10.108
  14. Kim SK, Jung J, Jung JH, et al. Hypoglycemic efficacy and safety of Momordica charantia (bitter melon) in patients with type 2 diabetes mellitus. Complement Ther Med. 2020 Aug;52:102524. doi: 10.1016/j.ctim.2020.102524. PubMed
  15. Unsal O, Sütcüoglu O, Yazici O. Dangerous interaction of bitter melon (Momordica charantia) with pazopanib: a case of acute pancreatitis. J Oncol Pharm Pract 2022;28(2):486-8.
  16. Bae W, Kim S, Choi J, et al. Acute interstitial nephritis associated with ingesting a Momordica charantia extract: a case report. Medicine (Baltimore) 2021;100(27):e26606. PubMed
  17. Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
  18. Kim B, Lee HS, Kim HJ, et al. Momordica charantia (bitter melon) efficacy and safety on glucose metabolism in Korean prediabetes participants: a 12-week, randomized clinical study. Food Sci Biotechnol 2022;32(5):697-704. PubMed

See these in context on the Bitter Melon monograph →

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Gotu Kola 18 references
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Tinospora Cordifolia 16 references
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Guggul 21 references
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Indian Long Pepper 12 references
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Neem 28 references
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Indian Gooseberry 6 references
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Holy Basil 8 references
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European Barberry 15 references
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Turmeric 102 references
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See these in context on the Turmeric monograph →

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Black Pepper 29 references
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Ceylon Cinnamon 22 references
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  8. Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
  9. Ranasinghe P, Jayawardena R, Galappaththy P, et al. Response to Akilen et al. Efficacy and safety of 'true' cinnamon (Cinnamomum zeylanicum) as a pharmaceutical agent in diabetes: a systematic review and meta-analysis. Diabet Med 2013 Apr;30(4):506-7.
  10. Oliveira JdA, da Silva IC, Trindade LA, et al. Safety and tolerability of essential oil from Cinnamomum zeylanicum blume leaves with action on oral candidosis and its effect on the physical properties of the acylic resin. Evid Based Complement Alternat Me
  11. Ranasinghe P, Pigera S, Premakumara GA, et al. Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review. BMC Complement Altern Med 2013;13:275. PubMed
  12. Ranasinghe P, Galappaththy P. Health benefits of Ceylon cinnamon (Cinnamomum zeylanicum): a summary of the current evidence. Ceylon Med J 2016;61(1):1-5. PubMed
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  14. Wansi SL, Nyadjeu P, Ngamga D, et al. Blood pressure lowering effect of the ethanol extract from the stembark of Cinnamomum zeylanicum (lauraceae) in rats. Pharmacol online 2007;3:166-76.
  15. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
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  21. Zobeiri M, Parvizi F, Shahpiri Z, et al. Evaluation of the effectiveness of cinnamon oil soft capsule in patients with functional dyspepsia: A randomized double-blind placebo-controlled clinical trial. Evid Based Complement Alternat Med 2021;2021:6634115. PubMed
  22. Chase C, Doyle A, John SS, Laurent T, Griffith S. Post-operative haemorrhage secondary to cinnamon use. A case report. Int J Surg Case Rep 2022;95:107179. PubMed

See these in context on the Ceylon Cinnamon monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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