Major interaction on record — check this product against your medications before combining. Based on 1 of 7 ingredients. Check your meds →
Dietary supplement

Surge XMP Fruit Punch Ingredients & Drug Interactions

by ANS

Surge XMP Fruit Punch label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Surge XMP Fruit Punch against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Surge XMP Fruit Punch is a dietary supplement by ANS with 7 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,172 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dietary Fiber. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Surge XMP Fruit Punch by ANS

Ask about any prescription or over-the-counter medication and we check it for interactions with Surge XMP Fruit Punch by ANS — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Surge XMP Fruit Punch by ANS

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 27 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (21,079 mg) without saying how much of each component you get.
  • “Nitrovascular Blend” is a proprietary blend — the label gives one combined amount (5,020 mg) without saying how much of each component you get.
  • “ATP Volumizing Blend” is a proprietary blend — the label gives one combined amount (3,010 mg) without saying how much of each component you get.

Surge XMP Fruit Punch contains 26 ingredients, with 10 active compounds. The main amino acids are L-glutamine (for muscle recovery and immune support), L-leucine, L-isoleucine, L-valine (branched-chain amino acids for muscle protein synthesis), L-histidine, and arginine (for blood flow and nitrogen transport).

It also includes taurine (an amino-acid-like compound), creatine and creatine HCl (for muscle strength and energy), beta-alanine (CarnoSyn), ornithine, and citrulline malate for athletic performance and blood flow. The blend also contains caffeine anhydrous for mental alertness, methylsynephrine as a stimulant, N-acetyl-L-tyrosine (a form of the amino acid tyrosine), phenethylamine (R-beta-methylphenylethylamine), amla extract (Indian gooseberry), and kola nut.

Supporting ingredients include maltodextrin and waxy maize as carbohydrate sources. Inactive ingredients are listed as citric acid, artificial and natural fruit flavors, sucralose, acesulfame-potassium, silicon dioxide, and beet juice powder.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: explosive pre-workout for energy focus pump strength.
  • We looked for evidence on: Athletic performance, Cognitive function, muscle endurance, exercise capacity, workout intensity, muscle pump.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Ornithine is rated "Possibly Effective" for Athletic performance.
  • Also on file: Creatine is rated "Possibly Effective" for Athletic performance.

Caffeine is likely effective for mental alertness and athletic performance, and is effective for neonatal apnea and postoperative headache. Creatine (both monohydrate and HCl) is possibly effective for muscle strength, athletic performance, sarcopenia (age-related muscle loss), and cerebral creatine deficiency syndromes.

Beta-alanine is possibly effective for athletic and physical performance. Taurine is possibly effective for congestive heart failure and hepatitis, though possibly ineffective for weight loss.

Glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, critical illness, and recovery after surgery. L-histidine's evidence is limited: there's some support for cholera, but evidence for eczema, kidney failure, and rheumatoid arthritis is insufficient.

Ornithine is possibly effective for athletic performance. The effectiveness of phenethylamine, methylsynephrine, and amla extract for the claims made on sports products is not well established in our data.

The evidence, ingredient by ingredient Black Psyllium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 12 of the 14 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 14 of 14.
  • General safety write-ups exist for 14 of 14.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in this product are generally well tolerated in healthy adults at typical doses. Glutamine commonly causes gastrointestinal upset (belching, bloating, diarrhea, nausea), and rare cases of dizziness and mood changes (mania) have been reported in people with bipolar disorder.

Creatine may cause dehydration, diarrhea, muscle cramps, and water retention; people with kidney disease should be cautious. Caffeine can cause anxiety, insomnia, jitteriness, tremors, and headache, especially at high doses.

Beta-alanine typically causes harmless skin tingling and flushing that usually lasts about an hour. Methylsynephrine is a stimulant that has been linked to elevated blood pressure, heart palpitations, and arrhythmias—the supplement dexaprine (which contained methylsynephrine) was removed from the market in the Netherlands because of serious cardiac events.

Taurine is generally well tolerated but may cause constipation or diarrhea. Amla extract rarely caused gastrointestinal discomfort, fatigue, or muscle pain in clinical trials.

Side effects, ingredient by ingredient Black Psyllium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 10 of the 14 matched ingredients can interact with medications — Black Psyllium, Indian Gooseberry, Glutamine, Cola Nut, Caffeine, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 2,173 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this if you take ephedrine or other stimulants (Major risk), anticonvulsants like phenobarbital or carbamazepine, blood pressure medications, lithium, blood thinners or aspirin, diabetes drugs, the antipsychotic clozapine, sleep aids like pentobarbital, heart medications like dipyridamole, or MAOIs. The product contains caffeine and methylsynephrine—both stimulants—so combining them with other stimulant drugs or high-dose caffeine elsewhere could pose real risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Surge XMP is a multi-ingredient performance powder aimed at athletes wanting muscle support and endurance. If you take any prescription medications—especially blood pressure drugs, anticonvulsants, blood thinners, diabetes medications, antipsychotics, or MAOIs—you need to check this product with your pharmacist first, because several ingredients interact.

People with kidney disease should also talk to their doctor before using it, since creatine requires careful monitoring. Pregnant and breastfeeding women should skip this product, as safety hasn't been established for several key ingredients.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 16 of 27 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Surge XMP Fruit Punch, straight from the product label.

Brand ANS
Barcode (UPC) 859582001826
Net contents 690 Gram(s); 1.52 lbs
Market status On market
Date entered into DSLD Feb 26, 2014
DSLD ID 30731
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Surge XMP Fruit Punch by ANS, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
23 Scoop(s)
Maximum serving Sizes:
23 Scoop(s)
Servings per container
30
UPC/BARCODE
859582001826
IngredientAmount% DV
Calories28 {Calories}--
Total Carbohydrates9 Gram(s)4%
L-Glutamine0 NP--
Sugar6 Gram(s)--
Calories from Fat0 {Calories}--
Dietary Fiber0 Gram(s)--
Protein0 Gram(s)--
Saturated Fat0 Gram(s)--
Trans Fat0 Gram(s)--
Cholesterol0 mg--
Total Fat0 Gram(s)--
Maltodextrin0 NP--
L-Leucine0 NP--
Waxy Maize0 NP--
L-Isoleucine0 NP--
Taurine0 NP--
Creatine HCl0 NP--
L-Valine0 NP--
L-Histidine0 NP--
Caffeine Anhydrous295 mg--
Proprietary Blend21079 mg--
N-Acetyl-L-Tyrosine0 NP--
CarnoSyn0 NP--
Arginine0 NP--
L-Norvaline0 NP--
Methylsynephrine0 NP--
Kola Nut0 NP--
Arginine AKG0 NP--
Amla extract0 NP--
Ornithine AKG0 NP--
Creatine0 NP--
R-Beta-Methylphenylethylamine0 NP--
DiArginine Malate0 NP--
Citrulline Malate 1:10 NP--
Nitrovascular Blend5020 mg--
ATP Volumizing Blend3010 mg--
Magnesium Creatine-Chelate0 NP--
Creatine Mono0 NP--
Extreme Energy Blend1976 mg--
Mucuna Pruriens0 NP--
Amino Recovery Blend11073 mg--

Other ingredients: Citric Acid, Artificial and Natural Fruit Flavors, Sucralose, Acesulfame-Potassium, Silicon Dioxide, Beet juice powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

SURGE XMP Xtreme Muscle Performance *ANS SURGE is an Explosive Pre-Workout Formula designed for Energy, Focus, Pump, Strength, and Intensity. *The Hydrosoluble ATP Volumizing Blend is delivered into your system quickly, allowing for Maxximum absorption and ATP-supporting actions.

ANS

ULTRA GROWTH PRE-WORKOUT

*Add in the Amino Recovery Complex with L-Glutamine, Taurine, and Glycine and you have the most comprehensive Pre-Workout Supplement available!

{QR Code}

Settling may occur.

EXPLOSIVE ENERGY & FOCUS POWERFUL NITRIC OXIDE DELIVERY

Formula

*Our Nitric Oxide blend promotes a dramatic "pump" with L-Arginine AKG combined with the Waxy Maize Nutrient Delivery System by transporting blood flow into the muscle for Maxximum Cell Volumization, Vascularity and Size.

ENHANCED CREATINE VOLUMIZING BLEND

Caution: This product contains caffeine.

FDA Statement of Identity

DIETARY SUPPLEMENT

Brand IP Statement(s)

*The patented CarnoSyn(R) Beta-Alanine helps increase the working capacity of muscle to delay fatigue during workouts for Maxximum endurance.

Kre-Alkalyn(R) is a registered trademark of All American(R) Pharmaceutical and Natural Foods Corp. Kre-Alkalyn(R) is a US-patented product registered to All American(R) Pharmaceutical (US patent #6,399,661). International and additional US patents pending. All rights reserved. Creatine Magna-Power(R) is a registered trademark of Albion Laboratories, Inc., covered by U.S. patent 6,114,379. CarnoSyn(R) is a registered trademark of Natural Alternatives International (NAI), covered by U.S. patents 5,965,596, 6,172,098, 6,426,361, 6,680,294.

Seals/Symbols

f {Facebook}

t {Twitter}

CREATINE MagnaPOWER(R)

Kre-Alkalyn(R) + pH-Correct Creatine(TM)

CarnoSyn(R) Carnsosine Synthesizer

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 serving of SURGE daily with 4 to 8 ounces of water or your favorite juice (30 minutes before workout). For enhanced results, SURGE may be taken with PowerMaxx, Post BCAA, DAA Test 5, or Test D-Aspartic.

Precautions

WARNING: Not intended for use by persons under age 18.

Do not exceed recommended dose.

Do not consume synephrine or caffeine from other sources, including but not limited to, coffee, tea, soda and other dietary supplements or medications containing phenylephrine or caffeine. Contains caffeine. Do not use for more than 8 weeks. Consult with your physician prior to use if you are pregnant or nursing, or if you are taking medication, including but not limited to MAOI inhibitors, antidepressants, aspirin, nonsteroidal anti-inflammatory drugs or products containing phylephrine, ephedrine, pseudoephedrine, or other stimulants.

Consult your physician prior to use if you have a medical condition, including but not limited to, heart, liver, kidney, or thyroid disease, psychiatric or epileptic disorders, difficulty urinating, diabetes, high blood pressure, cardiac arrhythmia, recurrent headaches, enlarged prostate or glaucoma. Discontinue 2 weeks prior to surgery or if you experience rapid heart beat, dizziness, severe headache or shortness of breath. Not intended for use by those with a medical condition.

Use only as directed. Do not exceed recommended daily intake. This product is intended for use by healthy individuals only.

Do not use this product if you are pregnant or nursing or have any medical condition.

KEEP OUT OF REACH OF CHILDREN.

Allergen Warning: Manufactured on equipment which processes products containing milk, eggs, soybeans, wheat, shellfish, fish oil, tree nuts, and peanut flavor.

Caution: This product contains caffeine. Use caution when using with any other caffeinated products or if you are caffeine-sensitive.

This product is not recommended for anyone under the age of 18.

Also see warning below.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Surge XMP Fruit Punch by ANS label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Surge XMP Fruit Punch label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Surge XMP Fruit Punch by ANS

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size23 Scoop(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

6 Gram(s) per serving

Dietary Fiber

Interacts with
2,025 drugs
0 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

0 Gram(s) per serving

Proprietary Blend

21079 mg per serving
  • › Nitrovascular Blend
  • › ATP Volumizing Blend
  • › Extreme Energy Blend
  • › Amino Recovery Blend

Other (inactive) ingredients: Citric Acid, Artificial and Natural Fruit Flavors, Sucralose, Acesulfame-Potassium, Silicon Dioxide, Beet juice powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Surge XMP Fruit Punch by ANS Drug Interactions

Want to check YOUR meds against Surge XMP Fruit Punch?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,172Drugs
26 Major 1,003 Moderate 1,143 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025

Individual Drug Interactions

The ingredients in Surge XMP Fruit Punch interact with 2,172 drugs. Click any drug to see the details.

1 of the 7 ingredients in Surge XMP Fruit Punch interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber

Each ingredient & the kinds of drugs it affects

For each ingredient in Surge XMP Fruit Punch with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Surge XMP Fruit Punch, from the product label.

ANS

See all ANS products
Name
ANS(R) ADVANCED NUTRITION SYSTEMS, LLC
City
Greenville
State
SC
ZipCode
29607
Phone Number
1.888.247.5326
Web Address
www.advanced247.com
Pharmacist Counseling Corner

Surge XMP Fruit Punch by ANS: Common Questions

Does Surge XMP Fruit Punch by ANS interact with any medications?
Yes. Based on its ingredients, Surge XMP Fruit Punch has a known interaction with 2,172 medications, including 26 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Surge XMP Fruit Punch contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me build muscle?
It contains several ingredients studied for muscle: creatine and beta-alanine are possibly effective for muscle strength and athletic performance, and branched-chain amino acids (leucine, isoleucine, valine) and glutamine are used for muscle recovery. The evidence is solid for some of these, but results also depend on training and diet.
Why does it make my skin tingle?
That's likely the beta-alanine (CarnoSyn). It commonly causes a harmless pins-and-needles feeling (paresthesia) on the scalp and skin that usually starts within 20 minutes and lasts about an hour. It's more noticeable at higher doses but isn't dangerous.
Is it safe if I'm pregnant or nursing?
No. Safety hasn't been established for creatine, beta-alanine, methylsynephrine, phenethylamine, ornithine, and amla extract during pregnancy and breastfeeding. Glutamine, taurine, and L-histidine are rated likely safe, but because the product as a whole hasn't been studied in pregnancy or lactation, you should avoid it and talk to your doctor or midwife.
How much caffeine is in one serving?
The facts we have don't list the amount of caffeine anhydrous per serving, only that it's included. You'll want to check the label on your package or contact ANS directly to know your total caffeine intake, especially if you consume other caffeine sources.
Will it make me jittery or anxious?
Possibly. The product contains caffeine and methylsynephrine, both stimulants. Common side effects include anxiety, restlessness, jitteriness, insomnia, and tremors. If you're sensitive to caffeine or stimulants, start with a smaller dose and see how you feel.
Could it upset my stomach?
Yes. Glutamine commonly causes belching, bloating, constipation, diarrhea, and nausea. Creatine may also cause diarrhea and gastrointestinal upset. Taking it with food and staying well hydrated may help reduce these effects.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Surge XMP Fruit Punch is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Surge XMP Fruit Punch label
Go deeper

The Full Monographs Behind Surge XMP Fruit Punch’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph →
Sources

Sources & How We Checked

Surge XMP Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 658 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
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Indian Gooseberry 6 references
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Ornithine 1 reference
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