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Dietary supplement

ZanthoSyn 12 mg Ingredients & Drug Interactions

by Cardax

ZanthoSyn 12 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ZanthoSyn 12 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ZanthoSyn 12 mg is a dietary supplement by Cardax with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 673 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against ZanthoSyn 12 mg by Cardax

Ask about any prescription or over-the-counter medication and we check it for interactions with ZanthoSyn 12 mg by Cardax — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of ZanthoSyn 12 mg by Cardax

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

ZanthoSyn 12 mg is a single-ingredient supplement: astaxanthin, a carotenoid (a type of plant pigment) with antioxidant properties. The capsule itself and the inactive ingredients — modified food starch, tapioca, microcrystalline cellulose, corn starch, glucose syrup, sodium ascorbate, and DL-alpha-tocopherol — are excipients used to deliver and stabilize the active ingredient.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: anti-inflammatory support for joint, cardiovascular, liver and metabolic health.
  • We looked for evidence on: Osteoarthritis, Rheumatoid arthritis (RA), Heart failure, Hypertension, Hyperlipidemia, Stroke — and 4 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD) (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Heart failure, Diabetes, Hyperlipidemia, Hypertension, and more.

The evidence for astaxanthin's effectiveness is currently insufficient to rate. The data we hold doesn't support reliable claims for age-related cognitive decline, macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

If you're considering this supplement for one of these purposes, the science isn't there yet to say it'll help.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are mild — abdominal pain, diarrhea, and red-colored stools (the pigment can tint your stool).

At the 12 mg dose in this product, serious side effects are uncommon, but a much higher dose (40 mg daily) has caused severe stomach pain in a small number of users. Regarding pregnancy and breastfeeding: there isn't enough safety data to recommend astaxanthin during either.

Talk with your doctor or pharmacist about whether it's right for you in these situations.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 674 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Cardax ZanthoSyn, check with your doctor or pharmacist about any medications you're on that are metabolized by CYP3A4 or CYP2B6 liver enzymes — astaxanthin may theoretically lower their blood levels. Use the medication search tool on this page to confirm your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

ZanthoSyn 12 mg is a single-ingredient astaxanthin supplement that's generally well tolerated at this dose. The main concern is whether it might lower the effectiveness of drugs your liver metabolizes — something to check with your own doctor or pharmacist before you start.

The evidence for its benefits isn't strong yet, so be clear on why you're taking it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ZanthoSyn 12 mg, straight from the product label.

Brand Cardax
Barcode (UPC) 861098000309
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243986
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ZanthoSyn 12 mg by Cardax, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
861098000309
IngredientAmount% DV
Astaxanthin12 mg--

Other ingredients: modified Food Starch, Tapioca Capsule, Microcrystalline Cellulose, Corn Starch, Glucose Syrup, Sodium Ascorbate, DL-Alpha-Tocopherol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

ZanthoSyn is a pure and highly absorbed form of astaxanthin recommended by doctors. Astaxanthin is a clinically studied ingredient with safe anti-inflammatory activity that supports: Joint health Cardiovascular health Liver health Metabolic health

60 Capsules / 12 mg

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 capsule daily or as directed by a healthcare professional. For optimal absorption, take after a meal containing healthy fats.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Safe anti-inflammatory for health & longevity

Vegan friendly

Non-GMO

FDA Statement of Identity

Astaxanthin Supplement

Seals/Symbols

Physician Endorsed

Precautions

Do not use if safety seal is broken or missing.

Consult your physician before use if you are pregnant, nursing, taking medication, or have a medical condition.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ZanthoSyn 12 mg by Cardax label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ZanthoSyn 12 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ZanthoSyn 12 mg by Cardax

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Astaxanthin

Interacts with
673 drugs
12 mg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Modified Food Starch, Tapioca Capsule, Microcrystalline Cellulose, Corn Starch, Glucose Syrup, Sodium Ascorbate, DL-Alpha-Tocopherol. These complete the product’s ingredient list but are not active constituents.

Interaction report

ZanthoSyn 12 mg by Cardax Drug Interactions

Want to check YOUR meds against ZanthoSyn 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
673Drugs
673 Moderate

Ingredients driving the most interactions

Astaxanthin 673

Individual Drug Interactions

The ingredients in ZanthoSyn 12 mg interact with 673 drugs. Click any drug to see the details.

1 of the 1 ingredient in ZanthoSyn 12 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in ZanthoSyn 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 673 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ZanthoSyn 12 mg, from the product label.

Cardax

See all Cardax products
Name
Cardax, Inc.
City
Honolulu
State
HI
ZipCode
96822
Phone Number
1-800-618-3050
Web Address
zanthosyn.com
Pharmacist Counseling Corner

ZanthoSyn 12 mg by Cardax: Common Questions

Does ZanthoSyn 12 mg by Cardax interact with any medications?
Yes. Based on its ingredients, ZanthoSyn 12 mg has a known interaction with 673 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ZanthoSyn 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take ZanthoSyn while I'm pregnant or breastfeeding?
There isn't enough safety data on astaxanthin in pregnancy or breastfeeding. The safety data advises against use in both situations. Talk with your doctor or pharmacist about your individual circumstances.
Will ZanthoSyn help with brain fog or memory problems?
The evidence for astaxanthin in age-related cognitive decline or Alzheimer disease is insufficient to rate. We can't say from the data we hold whether it will or won't help.
What side effects should I expect?
Most people tolerate astaxanthin well. You might notice abdominal pain, diarrhea, or red-colored stools — the pigment can tint your stool. Serious side effects are uncommon at the 12 mg dose.
Is this supplement safe to take long-term?
Astaxanthin is generally well tolerated in studies, but long-term safety data are limited. If you're planning to take it for months or years, check in with your doctor or pharmacist.
What is astaxanthin?
Astaxanthin is a carotenoid — a naturally occurring pigment from certain plants and algae — with antioxidant properties. It's what gives salmon and flamingos their pink color.
Will this interact with my blood pressure or cholesterol medication?
Many blood pressure and cholesterol drugs are processed through the liver enzymes CYP3A4 or CYP2B6, which astaxanthin may theoretically affect. Use the medication search tool on this page to check your specific drugs, and then talk with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ZanthoSyn 12 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ZanthoSyn 12 mg label
Go deeper

The Full Monographs Behind ZanthoSyn 12 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 673 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

ZanthoSyn 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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